608
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Chloromethylisothiazolinone induces ER stress-induced stress granule formation in human keratinocytes

, ORCID Icon &
Pages 171-179 | Received 13 Mar 2023, Accepted 18 Aug 2023, Published online: 23 Aug 2023

References

  • Adomavicius T, Guaita M, Zhou Y, Jennings MD, Latif Z, Roseman AM, Pavitt GD. 2019. The structural basis of translational control by eIF2 phosphorylation. Nat Commun. 10:2136. doi:10.1038/s41467-019-10167-3.
  • Cambronero-Urena A, Choi S, Choi S, Kim KK, Kim EM. 2021. Polyhexamethylene guanidine phosphate, chloromethylisothiazolinone, and particulate matter are dispensable for stress granule formation in human airway epithelial cells. Anim Cells Syst. 25:146–151. doi:10.1080/19768354.2021.1931442.
  • Campos-Melo D, Hawley ZCE, Droppelmann CA, Strong MJ. 2021. The integral role of RNA in stress granule formation and function. Front Cell Dev Biol. 9:621779. doi:10.3389/fcell.2021.621779.
  • Chambers ES, Vukmanovic-Stejic M. 2020. Skin barrier immunity and ageing. Immunology. 160:116–125. doi:10.1111/imm.13152.
  • Corbet GA, Burke JM, Bublitz GR, Tay JW, Parker R. 2022. dsRNA-induced condensation of antiviral proteins modulates PKR activity. Proc Natl Acad Sci USA. 119:e2204235119. doi:10.1073/pnas.2204235119.
  • De K, Jayabalan AK, Mariappan R, Ramasamy VS, Ohn T. 2022. Dihydrocapsaicin induces translational repression and stress granule through HRI-eIF2alpha phosphorylation axis. Biochem Biophys Res Commun. 588:125–132. doi:10.1016/j.bbrc.2021.12.049.
  • Dimasi P, Quintiero A, Shelkovnikova TA, Buchman VL. 2017. Modulation of p-eIF2alpha cellular levels and stress granule assembly/disassembly by trehalose. Sci Rep. 7:44088. doi:10.1038/srep44088.
  • Donnelly N, Gorman AM, Gupta S, Samali A. 2013. The eIF2alpha kinases: their structures and functions. Cell Mol Life Sci. 70:3493–3511. doi:10.1007/s00018-012-1252-6.
  • Fay MM, Columbo D, Cotter C, Friend C, Henry S, Hoppe M, Karabelas P, Lamy C, Lawell M, Monteith S, et al. 2021. Bisphenol A promotes stress granule assembly and modulates the integrated stress response. Biol Open. 10:bio057539. doi:10.1242/bio.057539.
  • Glass L, Wente SR. 2019. Gle1 mediates stress granule-dependent survival during chemotoxic stress. Adv Biol Regul. 71:156–171. doi:10.1016/j.jbior.2018.09.007.
  • Go HN, Lee SH, Cho HJ, Ahn JR, Kang MJ, Lee SY, Hong SJ. 2020. Effects of chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) on Th2/Th17-related immune modulation in an atopic dermatitis mouse model. Sci Rep. 10:4099. doi:10.1038/s41598-020-60966-8.
  • Han J, Back SH, Hur J, Lin YH, Gildersleeve R, Shan J, Yuan CL, Krokowski D, Wang S, Hatzoglou M, et al. 2013. ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. Nat Cell Biol. 15:481–490. doi:10.1038/ncb2738.
  • Hofmann S, Kedersha N, Anderson P, Ivanov P. 2021. Molecular mechanisms of stress granule assembly and disassembly. Biochim Biophys Acta Mol Cell Res. 1868:118876. doi:10.1016/j.bbamcr.2020.118876.
  • Hwang JH, Jeong H, Jung YO, Nam KT, Lim KM. 2021. Skin irritation and inhalation toxicity of biocides evaluated with reconstructed human epidermis and airway models. Food Chem Toxicol. 150:112064. doi:10.1016/j.fct.2021.112064.
  • Jennings MD, Zhou Y, Mohammad-Qureshi SS, Bennett D, Pavitt GD. 2013. eIF2B promotes eIF5 dissociation from eIF2*GDP to facilitate guanine nucleotide exchange for translation initiation. Genes Dev. 27:2696–2707. doi:10.1101/gad.231514.113.
  • Jung H, Jung D, Lee J, Ki W, Lee JM, Kim EM, Nam MS, Kim KK. 2022. Bioactive peptides in the pancreatin-hydrolysates of whey protein support cell proliferation and scavenge reactive oxygen species. Anim Cells Syst. 26:232–242. doi:10.1080/19768354.2022.2130425.
  • Kedersha N, Chen S, Gilks N, Li W, Miller IJ, Stahl J, Anderson P. 2002. Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules. Mol Biol Cell. 13:195–210. doi:10.1091/mbc.01-05-0221.
  • Kershaw CJ, Jennings MD, Cortopassi F, Guaita M, Al-Ghafli H, Pavitt GD. 2021. GTP binding to translation factor eIF2B stimulates its guanine nucleotide exchange activity. iScience. 24:103454. doi:10.1016/j.isci.2021.103454.
  • Kim S, Seo M, Na M, Kim J. 2021. Investigation on combined inhalation exposure scenarios to biocidal mixtures: biocidal and household chemical products in South Korea. Toxics. 9:32. doi:10.3390/toxics9020032.
  • Lee AK, Klein J, Fon Tacer K, Lord T, Oatley MJ, Oatley JM, Porter SN, Pruett-Miller SM, Tikhonova EB, Karamyshev AL, et al. 2020. Translational repression of G3BP in cancer and germ cells suppresses stress granules and enhances stress tolerance. Mol Cell. 79:645–659 e649. doi:10.1016/j.molcel.2020.06.037.
  • Lee SY, Park DU, Do KH, Jang SJ, Hong SJ. 2019. The pathological findings of chloromethylisothiazolinone and methylisothiazolinone-associated lung injury. J Korean Med Sci. 34:e102. doi:10.3346/jkms.2019.34.e102.
  • Malvezzi AM, Arico M, Souza-Melo N, Dos Santos GP, Bittencourt-Cunha P, Holetz FB, Schenkman S. 2020. GCN2-like kinase modulates stress granule formation during nutritional stress in Trypanosoma cruzi. Front Cell Infect Microbiol. 10:149. doi:10.3389/fcimb.2020.00149.
  • McInerney GM, Kedersha NL, Kaufman RJ, Anderson P, Liljestrom P. 2005. Importance of eIF2alpha phosphorylation and stress granule assembly in alphavirus translation regulation. Mol Biol Cell. 16:3753–3763. doi:10.1091/mbc.e05-02-0124.
  • Namkoong S, Ho A, Woo YM, Kwak H, Lee JH. 2018. Systematic characterization of stress-induced RNA granulation. Mol Cell. 70:175–187 e178. doi:10.1016/j.molcel.2018.02.025.
  • Obed C, Wu M, Chen Y, An R, Cai H, Luo Q, Yu L, Wang J, Liu F, Shen J, et al. 2022. Toxoplasma gondii dense granule protein 3 promotes endoplasmic reticulum stress-induced apoptosis by activating the PERK pathway. Parasit Vectors. 15:276. doi:10.1186/s13071-022-05394-5.
  • Park DU, Park SK, Kim J, Park J, Ryu SH, Park JH, Lee SY, Oh HB, Kim S, Zoh KE, et al. 2020. Characteristics of exposure to chloromethylisothiazolinone (CMIT) and methylisothiazolinone (MIT) among humidifier disinfectant-associated lung injury (HDLI) patients in South Korea. Molecules. 25:5284. doi:10.3390/molecules25225284.
  • Reineke LC, Dougherty JD, Pierre P, Lloyd RE. 2012. Large G3BP-induced granules trigger eIF2alpha phosphorylation. Mol Biol Cell. 23:3499–3510. doi:10.1091/mbc.E12-05-0385.
  • Reineke LC, Neilson JR. 2019. Differences between acute and chronic stress granules, and how these differences may impact function in human disease. Biochem Pharmacol. 162:123–131. doi:10.1016/j.bcp.2018.10.009.
  • Sundaram A, Appathurai S, Plumb R, Mariappan M. 2018. Dynamic changes in complexes of IRE1alpha, PERK, and ATF6alpha during endoplasmic reticulum stress. Mol Biol Cell. 29:1376–1388. doi:10.1091/mbc.E17-10-0594.
  • Tyagi R, Shahani N, Gorgen L, Ferretti M, Pryor W, Chen PY, Swarnkar S, Worley PF, Karbstein K, Snyder SH, et al. 2015. Rheb inhibits protein synthesis by activating the PERK-eIF2alpha signaling cascade. Cell Rep. 10:684–693. doi:10.1016/j.celrep.2015.01.014.
  • Wang F, Li J, Fan S, Jin Z, Huang C. 2020. Targeting stress granules: A novel therapeutic strategy for human diseases. Pharmacol Res. 161:105143. doi:10.1016/j.phrs.2020.105143.
  • Wheeler JR, Matheny T, Jain S, Abrisch R, Parker R. 2016. Distinct stages in stress granule assembly and disassembly. Elife. 5:e18413. doi:10.7554/eLife.18413.
  • Zhang C, Merana GR, Harris-Tryon T, Scharschmidt TC. 2022. Skin immunity: dissecting the complex biology of our body's outer barrier. Mucosal Immunol. 15:551–561. doi:10.1038/s41385-022-00505-y.