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Original Article

Prevalence of Her3 in gastric cancer and its association with molecular prognostic markers: a Saudi cohort based study

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Article: 1574532 | Received 10 Jun 2018, Accepted 16 Jan 2019, Published online: 27 Mar 2019

References

  • Sukawa Y, Yamamoto H, Nosho K, et al. HER2 expression and PI3K-Akt pathway alterations in gastric cancer. Digestion. 2014;89(1):1–7.
  • Amann J, Kalyankrishna S, Massion PP, et al. Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer. Cancer Res. 2005 Jan 1;65(1):226–235.
  • Cao GD, Chen K, Xiong MM, et al. HER3, but not HER4, plays an essential role in the clinicopathology and prognosis of gastric cancer: a meta-analysis. PloS one. 2016 Aug 18;11(8):e0161219.
  • Berger MB, Mendrola JM, Lemmon MA. ErbB3/HER3 does not homodimerize upon neuregulin binding at the cell surface. FEBS Lett. 2004 Jul 2;569(1–3):332–336.
  • Le Wilks ST. Potential of overcoming resistance to HER2-targeted therapies through the PI3K/Akt/mTOR pathway. Breast. 2015 Oct;24(5):548–555.
  • Mishra R, Patel H, Alanazi S, et al. HER3 signaling and targeted therapy in cancer. Oncol Rev. 2018 May 16;12(1):355.
  • Wang L, Yuan H, Li Y, et al. The role of HER3 in gastric cancer. Biomed Pharmacother. 2014 Jul;68(6):809–812.
  • Jaiswal BS, Kljavin NM, Stawiski EW, et al. Oncogenic ERBB3 mutations in human cancers. Cancer Cell. 2013 May 13;23(5):603–617.
  • Cancer Incidence Report Saudi Arabia, Kingdom of Saudi Arabia, Council of Health Services. Saudi cancer registry, April 2014. [cited 2018 Jun 4]. Available from: www.scr.org.sa
  • Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand. 1965;64:31–49.
  • Zhang XL, Yang YS, Xu DP, et al. Comparative study on overexpression of HER2/neu and HER3 in gastric cancer. World J Surg. 2009 Oct;33(10):2112–2118.
  • Busuttil RA, Zapparoli GV, Haupt S, et al. Role of p53 in the progression of gastric cancer. Oncotarget. 2014 Dec 15;5(23):12016–12026.
  • Saricanbaz I, Karahacioglu E, Ekinci O, et al. Prognostic significance of expression of CD133 and Ki-67 in gastric cancer. Asian Pac J Cancer Prev. 2014;15(19):8215–8219.
  • Hayashi M, Inokuchi M, Takagi Y, et al. High expression of HER3 is associated with a decreased survival in gastric cancer. Clin Cancer Res. 2008 Dec 1;14(23):7843–7849.
  • Wu X, Chen Y, Li G, et al. Her3 is associated with poor survival of gastric adenocarcinoma: her3 promotes proliferation,survival and migration of human gastric cancer mediated by PI3K/AKT signaling pathway. Med Oncol. 2014 Apr;31(4):903.
  • Tang D, Liu CY, Shen D, et al. Assessment and prognostic analysis of EGFR, HER2, and HER3 protein expression in surgically resected gastric adenocarcinomas. Onco Targets Ther. 2014 Dec 16;8:7–14.
  • He XX, Ding L, Lin Y, et al. Protein expression of HER2, 3, 4 in gastric cancer: correlation with clinical features and survival. J Clin Pathol. 2015;68:374–380.
  • Alshomimi S, Alsaleem H. Comparing the treatment of gastric cancer between Korea and Saudi Arabia. Transl Gastroenterol Hepatol. 2017;2:32.
  • Sanidas EE, Filipe MI, Linehan J, et al. Expression of the c-erbB-3 gene product in gastric cancer. Int J Cancer. 1993 Jul 30;54(6):935–940.
  • Kobayashi M, Iwamatsu A, Shinohara-Kanda A, et al. Activation of ErbB3-PI3-kinase pathway is correlated with malignant phenotypes of adenocarcinomas. Oncogene. 2003 Mar 6;22(9):1294–1301.
  • Srini Srinivasan R, Leverton KE, Sheldon H, et al. Intracellular expression of the truncated extracellular domain of c-erbB-3/HER3. Cell Signal. 2001 May;13(5):321–330.
  • Jácome AA, Wohnrath DR, Scapulatempo NC, et al. Prognostic value of epidermal growth factor receptors in gastric cancer: a survival analysis by Weibull model incorporating long-term survivors. Gastric Cancer. 2014 Jan;17(1):76–86.
  • Ocana A, Vera-Badillo F, Seruga B, et al. HER3 overexpression and survival in solid tumors: a meta-analysis. J Natl Cancer Inst. 2013 Feb 20;105(4):266–273.
  • Ko GH, Go SI, Lee WS, et al. Prognostic impact of Ki-67 in patients with gastric cancer-the importance of depth of invasion and histologic differentiation. Medicine (Baltimore). 2017 Jun;96(25):e7181.
  • Al-Moundhri MS, Nirmala V, Al-Hadabi I, et al. The prognostic significance of p53, p27 kip1, p21, waf1, HER-2/neu, and Ki67 proteins expression in gastric cancer: a clinicopathological and immunohistochemical study of 121 Arab patients. J Surg Oncol. 2005 Sep 15;91(4):243–252.
  • Yallowitz AR, Li D, Lobko A, et al. Mutant p53 amplifies epidermal growth factor receptor family signaling to promote mammary tumorigenesis. Mol Cancer Res. 2015 Apr;13(4):743–754.