Evaluation of possible biomarkers for caries risk in children 6 to 12 years of age

References

• Biomarkers Definitions Working Group. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther. 2001;69(3): 89–9. .
   PubMed Web of Science ®Google Scholar
• Aronson JK, Ferner RE. Biomarkers-A General Review. Curr Protoc Pharmacol. 2017;17(76):9.23.1–9.23.17.
   Google Scholar
• Califf RM. Biomarker definitions and their applications. Exp Biol Med. 2018;243(3):213–221.
   PubMed Web of Science ®Google Scholar
• Kianoush N, Adler CJ, Nguyen KA, et al. Bacterial profile of dentine caries and the impact of pH on bacterial population diversity. PLoS One. 2014;9(3):e92940.
   PubMed Web of Science ®Google Scholar
• Twetman S. Prevention of dental caries as a non-communicable disease. Eur J Oral Sci. 2018;126(1):19–25.
   Google Scholar
• Di Pierro F, Zanvit A, Nobili P, et al. Cariogram outcome after 90 days of oral treatment with Streptococcus salivarius M18 in children at high risk fordental caries: results of a randomized, controlled study. Clin Cosmet Investig Dent. 2015;2015(7):107–113.
   Google Scholar
• Mira A, Artacho A, Camelo-Castillo A, et al. Salivary Immune and Metabolic Marker Analysis (SIMMA): a Diagnostic Test to Predict Caries Risk. Diagnostics (Basel). 2017;7(3):38.
   Google Scholar
• Hemadi AS, Huang R, Zhou Y, et al. Salivary proteins and microbiota as biomarkers for early childhood caries risk assessment. Int J Oral Sci. 2017;9(11):e1.
   PubMedGoogle Scholar
• Paqué PN, Herz C, Wiedemeier DB, et al. Salivary Biomarkers for Dental Caries Detection and Personalized Monitoring. J Pers Med. 2021;11(3):235.
   Web of Science ®Google Scholar
• Divaris K. Predicting Dental Caries Outcomes in Children: a “Risky” Concept. J Dent Res. 2016;95(3):248–254.
   Web of Science ®Google Scholar
• Piekoszewska-Ziętek P, Turska-Szybka A, Olczak-Kowalczyk D. Salivary proteins and peptides in the aetiology of caries in children: systematic literature review. Oral Dis. 2019;25(4):1048–1056.
   PubMed Web of Science ®Google Scholar
• Tao R, Jurevic RJ, Coulton KK, et al. Salivary antimicrobial peptide expression and dental caries experience in children. Antimicrob Agents Chemother. 2005;49(9):3883–3888.
   PubMed Web of Science ®Google Scholar
• Khurshid Z, Naseem M, Yahya I, et al. Significance and Diagnostic Role of Antimicrobial Cathelicidins (LL-37) Peptides in Oral Health. Biomolecules 2017;7(4):80.
   Web of Science ®Google Scholar
• Soesilawati P, Notopuro H, Yuliati Y, et al. The role of salivary sIgA as protection for dental caries activity in Indonesian children. Clinical Cosmet and Investigational Dentistry. 2019;11:291–295.
   PubMed Web of Science ®Google Scholar
• Speziale P, Arciola CR, Pietrocola G. Fibronectin and its role in human infective diseases. Cells. 2019;8(12):1516.
   PubMed Web of Science ®Google Scholar
• Llena-Puy MC, Montañana-Llorens C, Forner-Navarro L. Fibronectin levels in stimulated whole-saliva and their relationship with cariogenic oral bacteria. Int Dent J. 2000;50(1):57–59.
   Web of Science ®Google Scholar
• Park Y-D, Jang J-H, Oh Y-J, et al. Analyses of organic acids and inorganic anions and their relationship in human saliva before and after glucose intake. Arch Oral Biol. 2014;59(1):1–11.
   Web of Science ®Google Scholar
• Poureslami R, Re S, Poureslami. Concentration of Calcium, Phosphate and Fluoride Ions in Microbial Plaque and Saliva after Using CPP-ACP Paste in 6-9 year-old Children. J Dent Biomater. 2016;3(2):214–219.
   Google Scholar
• Margolis HC, Moreno EC. Composition and cariogenic potential of dental plaque fluid. Crit Rev Oral Biol Med. 1994;5(1):1–25.
   Google Scholar
• Chawda JG, Chaduvula N, Patel HR, et al. Salivary SIgA and dental caries activity. Indian Pediatr. 2011;48(9):719–721.
   Web of Science ®Google Scholar
• Omar OM, Khattab NM, Rashed LA. Glucosyltransferase B, immunoglobulin A, and caries experience among a group of Egyptian preschool children. J. Pediatr. Dent. 2012;79(2):63–68.
   Google Scholar
• Colombo NH, Ribas LF, Pereira JA, et al. Antimicrobial peptides in saliva of children with severe early childhood caries. Arch Oral Biol. 2016;69:40–46.
   PubMed Web of Science ®Google Scholar
• Lo Giudice G, Nicita F, Militi A, et al. Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children. Dent J. 2020;8(1):3.
   Google Scholar
• Lo Giudice G, Militi A, Nicita F, et al. Correlation between Oral Hygiene and IL-6 in Children. Dent J. 2020,8(3):91.
   Google Scholar
• Vitorino R, Lobo MJ, Duarte JR, et al. The role of salivary peptides in dental caries. Biomed Chromatogr. 2005;19(3):214–222.
   PubMed Web of Science ®Google Scholar
• Carpenter G, Cotroneo E, Moazzez R, et al. Composition of enamel pellicle from dental erosion patients. Caries Res. 2014;48(5):361–367.
   Web of Science ®Google Scholar
• Mutahar M, O’Toole S, Carpenter G, et al. Reduced statherin in acquired enamel pellicle on eroded teeth compared to healthy teeth in the same subjects: an in-vivo study. PLoS One. 2017;12(8):e0183660.
   Web of Science ®Google Scholar
• Yin A, Margolis HC, Yao Y, et al. Multi-component adsorption model for pellicle formation: the influence of salivary proteins and non-salivary phospho proteins on the binding of histatin 5 onto hydroxyapatite. Arch Oral Biol. 2006;51(2):102–110.
   Web of Science ®Google Scholar
• Rudney JD, Staikov RK, Johnson JD. Potential biomarkers of human salivary function: a modified proteomic approach. Archives of Oral Biolology. 2009;54(1):91–100.
   PubMed Web of Science ®Google Scholar
• Shimotoyodome A, Kobayashi H, Tokimitsu I, et al. Statherin and histatin 1 reduce parotid saliva-promoted Streptococcus mutans strain MT8148 adhesion to hydroxyapatite surfaces. Caries Res. 2006;40(5):403–411.
   Web of Science ®Google Scholar
• Razi MA, Qamar S, Singhal A, et al. Role of natural salivary defenses in the maintenance of healthy oral microbiota in children and adolescents. J Family Med Prim Care. 2020;9(3):1603–1607.
   Google Scholar
• Simón-Soro Á S-S, D’Auria G, Collado MC, et al. Revealing microbial recognition by specific antibodies. BMC Microbiol. 2015;15(1):132.
   Google Scholar
• Davidopoulou S, Diza E, Menexes G, et al. Salivary concentration of the antimicrobial peptide LL-37 in children. Arch Oral Biol. 2012;57(7):865–869.
   Web of Science ®Google Scholar
• Ribeiro TR, Dria KJ, de Carvalho CB, et al. Salivary peptide profile and its association with early childhood caries. Int J Paediatr Dent. 2013;23(3):225–234.
   PubMed Web of Science ®Google Scholar
• Hasty DL, Simpson WA. Effects of fibronectin and other salivary macromolecules on the adherence of Escherichia coli to buccal epithelial cells. Infect Immun. 1987;55(9):2103–2109.
   Web of Science ®Google Scholar
• Bagherian A, Asadikaram G. Comparison of some salivary characteristics between children with and without early childhood caries. Indian J Dent Res. 2012;23(5):628–632.
   Google Scholar
• Animireddy D, Reddy Bekkem VT, Vallala P, et al. Evaluation of pH, buffering capacity, viscosity and flow rate levels of saliva in caries-free, minimal caries and nursing caries children: an in vivo study. Contemp Clin Dent. 2014;5(3):324–328.
   Google Scholar
• Kuribayashi M, Kitasako Y, Matin K, et al. Intraoral pH measurement of carious lesions with qPCR of cariogenic bacteria to differentiate caries activity. J Dent. 2012;40(3):222–228.
   PubMed Web of Science ®Google Scholar
• Featherstone JD, Rodgers BE. Effect of acetic, lactic and other organic acids on the formation of artificial carious lesions. Caries Res. 1981;15(5):377–385.
   Web of Science ®Google Scholar
• Shahrabi MA, Nikfarjam JA, Alikhani AA, et al. A comparison of salivary calcium, phosphate, and alkaline phosphatase in children with severe, moderate caries, and caries free in Tehran’s kindergartens. J Indian Soc Pedod Prev Dent. 2008;26(2):74–77.
   Google Scholar
• Aruna S, Meenakshi B, Rama KV, et al. Salivary levels of calcium and phosphorus in children with and without early childhood caries: a pilot study. SRM J Res Dent Sci. 2020;11:72–75.
   Google Scholar
• Young DA, Featherstone JD. Caries management by risk assessment. Community Dent Oral Epidemiol. 2013;41(1):e53–63.
   Web of Science ®Google Scholar