1,699
Views
3
CrossRef citations to date
0
Altmetric
Original Article

Campylobacter concisus upregulates PD-L1 mRNA expression in IFN-γ sensitized intestinal epithelial cells and induces cell death in esophageal epithelial cells

, , , , , , & show all
Article: 1978732 | Received 08 Jun 2021, Accepted 06 Sep 2021, Published online: 14 Sep 2021

References

  • Lastovica AJ, On S, Zhang L. The family Campylobacteraceae. Springer-, Berlin, Heidelberg. 2014.
  • Zhang L. Campylobacter concisus and inflammatory bowel disease. World J Gastroenterol. 2014;20(5):1259.
  • Liu F, Ma R, Wang Y, et al. The clinical importance of Campylobacter concisus and other human hosted Campylobacter species. Front Cell Infect Microbiol. 2018;8:243.
  • Bernstein CN, Blanchard JF, Kliewer E, et al. Cancer risk in patients with inflammatory bowel disease: a population‐based study. Cancer. 2001;91(4):854–10.
  • Jensen AB, Larsen M, Gislum M, et al. Survival after colorectal cancer in patients with ulcerative colitis: a nationwide population-based Danish study. Am J Gastroenterol. 2006;101(6):1283–1287.
  • Taylor CC, Millien VO, Hou JK, et al. Association Between Inflammatory Bowel Disease and Colorectal Cancer Stage of Disease and Survival. J Surg Res. 2020;247:77–85.
  • Kaplan GG. The global burden of IBD: from 2015 to 2025. Nat Rev Gastroenterol Hepatol. 2015;12(12):720–727.
  • On SLW, Zhang J, Cornelius AJ, et al. Markers for discriminating Campylobacter concisus genomospecies using MALDI-TOF analysis. Curr Res Microb Sci. 2021;2:100019.
  • Liu F, Ma R, Tay CYA, et al. Genomic analysis of oral Campylobacter concisus strains identified a potential bacterial molecular marker associated with active Crohn’s disease. Emerg Microbes Infect. 2018;7:1–14.
  • Wang Y, Liu F, Zhang X, et al. Campylobacter concisus genomospecies 2 is better adapted to the human gastrointestinal tract as compared with Campylobacter concisus genomospecies 1. Front Physiol. 2017;8:543.
  • Liu F, Chen S, Luu LDW, et al. Analysis of complete Campylobacter concisus genomes identifies genomospecies features, secretion systems and novel plasmids and their association with severe ulcerative colitis. Microb Genom. 2020;6(11).
  • Macfarlane S, Furrie E, Macfarlane GT, et al. Microbial colonization of the upper gastrointestinal tract in patients with Barrett’s esophagus. Clin Infect Dis. 2007;45(1):29–38.
  • Blackett KL, Siddhi SS, Cleary S, et al. Oesophageal bacterial biofilm changes in gastro-oesophageal reflux disease, Barrett’s and oesophageal carcinoma: association or causality? Aliment Pharmacol Ther. 2013;37(11):1084–1092.
  • Mozaffari Namin B, Soltan Dallal MM, Ebrahimi Daryani N. The Effect of Campylobacter concisus on Expression of IL-18, TNF-α and p53 in Barrett’s Cell Lines. Jundishapur J Microbiol. 2015;8(12):e26393–e93.
  • Barrett NR. The lower esophagus lined by columnar epithelium. Surgery. 1957;41:881–894.
  • Shaheen NJ, Richter JE. Barrett’s oesophagus. Lancet. 2009;373(9666):850–861.
  • Runge TM, Abrams JA, Shaheen NJ. Epidemiology of Barrett’s Esophagus and Esophageal Adenocarcinoma. Gastrointest Endosc Clin N Am. 2015;44(2):203–231.
  • Cook MB, Wild CP, Forman D. A Systematic Review and Meta-Analysis of the Sex Ratio for Barrett’s Esophagus, Erosive Reflux Disease, and Nonerosive Reflux Disease. Am J Epidemiol. 2005;162(11):1050–1061.
  • Hvid-Jensen F, Pedersen L, Drewes AM, et al. Incidence of adenocarcinoma among patients with Barrett’s esophagus. N Engl J Med. 2011;365(15):1375–1383.
  • Mueller SN, Vanguri VK, Ha S-J, et al. PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice. J Clin Investig. 2010;120(7):2508–2515.
  • Guan J, Lim KS, Mekhail T, et al. Programmed Death Ligand-1 (PD-L1) Expression in the Programmed Death Receptor-1 (PD-1)/PD-L1 Blockade: a Key Player Against Various Cancers. Arch Pathol Lab Med. 2017;141(6):851–861.
  • Dong H, Chen L. B7-H1 pathway and its role in the evasion of tumor immunity. J Mol Med (Berl). 2003;81:281–287.
  • Keir ME, Butte MJ, Freeman GJ, et al. PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol. 2008;26(1):677–704.
  • Butte MJ, Keir ME, Phamduy TB, et al. Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity. 2007;27(1):111–122.
  • Dong H, Strome SE, Salomao DR, et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med. 2002;8(8):793–800.
  • Mühlbauer M, Fleck M, Schütz C, et al. PD-L1 is induced in hepatocytes by viral infection and by interferon-alpha and -gamma and mediates T cell apoptosis. J Hepatol. 2006;45(4):520–528.
  • Brown JA, Dorfman DM, Ma FR, et al. Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production. J Immunol. 2003;170(3):1257–1266.
  • Rajabian Z, Kalani F, Taghiloo S, et al. Over-Expression of Immunosuppressive Molecules, PD-L1 and PD-L2, in Ulcerative Colitis Patients. Iran J Immunol. 2019;16:62–70.
  • Van Der Kraak L, Goel G, Ramanan K, et al. 5-Fluorouracil upregulates cell surface B7-H1 (PD-L1) expression in gastrointestinal cancers. J Immunother Cancer. 2016;4(1):65.
  • Derks S, Nason KS, Liao X, et al. Epithelial PD-L2 Expression Marks Barrett’s Esophagus and Esophageal Adenocarcinoma. Cancer Immunol Res. 2015;3(10):1123–1129.
  • Ishida M, Iwai Y, Tanaka Y, et al. Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues. Immunol Lett. 2002;84(1):57–62.
  • Curiel TJ, Wei S, Dong H, et al. Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity. Nat Med. 2003;9(5):562–567.
  • Chen S, Crabill GA, Pritchard TS, et al. Mechanisms regulating PD-L1 expression on tumor and immune cells. J Immunother Cancer. 2019;7(1):305.
  • Yamazaki T, Akiba H, Iwai H, et al. Expression of programmed death 1 ligands by murine T cells and APC. J Immunol. 2002;169(10):5538–5545.
  • Chen L. Co-inhibitory molecules of the B7–CD28 family in the control of T-cell immunity. Nat Rev Immunol. 2004;4(5):336–347.
  • Ou J-N, Wiedeman AE, Stevens AM. TNF-α and TGF-β counter-regulate PD-L1 expression on monocytes in systemic lupus erythematosus. Sci Rep. 2012;2(1):295.
  • Kondo A, Yamashita T, Tamura H, et al. Interferon-γ and tumor necrosis factor-α induce an immunoinhibitory molecule, B7-H1, via nuclear factor-κB activation in blasts in myelodysplastic syndromes. Blood. 2010;116(7):1124–1131.
  • Wang X, Yang L, Huang F, et al. Inflammatory cytokines IL-17 and TNF-α up-regulate PD-L1 expression in human prostate and colon cancer cells. Immunol Lett. 2017;184:7–14.
  • Chulkina M, Beswick EJ, Pinchuk IV. Role of PD-L1 in Gut Mucosa Tolerance and Chronic Inflammation. Int J Mol Sci. 2020;21(23):9165.
  • Wu -Y-Y, Lin C-W, Cheng K-S, et al. Increased programmed death-ligand-1 expression in human gastric epithelial cells in Helicobacter pylori infection. Clin Exp Immunol. 2010;161(3):551–559.
  • Holokai L, Chakrabarti J, Broda T, et al. Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection. PLoS Pathog. 2019;15(1):e1007468.
  • Lee SA, Wang Y, Liu F, et al. Escherichia coli K12 Upregulates Programmed Cell Death Ligand 1 (PD-L1) Expression in Gamma Interferon-Sensitized Intestinal Epithelial Cells via the NF-κB Pathway. Infect Immun. 2020;89(1):e00618-20.
  • Zhang L, Budiman V, Day AS, Zhang L, Budiman V, Day AS, Mitchell H, Lemberg DA, Riordan SM, et al. Isolation and Detection of Campylobacter concisus from Saliva of Healthy Individuals and Patients with Inflammatory Bowel Disease. J Clin Microbiol. 2010;48(8):2965–2967.
  • Ismail Y, Mahendran V, Octavia S, Day AS, Riordan SM, Grimm MC, et al. Investigation of the enteric pathogenic potential of oral Campylobacter concisus strains isolated from patients with inflammatory bowel disease. PloS One. 2012;7:e38217.
  • Chung HKL, Tay A, Octavia S, et al. Genome analysis of Campylobacter concisus strains from patients with inflammatory bowel disease and gastroenteritis provides new insights into pathogenicity. Sci Rep. 2016;6(1):1–14.
  • Bankevich A, Nurk S, Antipov D, et al. SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing. J Comput Biol. 2012;19(5):455–477.
  • Tatusova T, DiCuccio M, Badretdin A, et al. NCBI prokaryotic genome annotation pipeline. Nucleic Acids Res. 2016;44(14):6614–6624.
  • Aziz RK, Bartels D, Best AA, et al. The RAST Server: rapid annotations using subsystems technology. BMC Genomics. 2008;9(1):75.
  • Zhang L, Man SM, Day AS, et al. Detection and Isolation of Campylobacter Species Other than C. jejuni from Children with Crohn’s Disease. J Clin Microbiol. 2009;47(2):453–455.
  • Mahendran V, Riordan SM, Grimm MC, et al. Prevalence of Campylobacter Species in Adult Crohn’s Disease and the Preferential Colonization Sites of Campylobacter Species in the Human Intestine. PloS One. 2011;6(9):e25417.
  • Mahendran V, Octavia S, Demirbas OF, et al. Delineation of genetic relatedness and population structure of oral and enteric Campylobacter concisus strains by analysis of housekeeping genes. Microbiology. 2015;161(8):1600–1612.
  • Konishi J, Yamazaki K, Azuma M, et al. B7-H1 Expression on Non-Small Cell Lung Cancer Cells and Its Relationship with Tumor-Infiltrating Lymphocytes and Their PD-1 Expression. Clin Cancer Res. 2004;10(15):5094–5100.
  • Livak KJ, Schmittgen TD. Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method. Methods. 2001;25(4):402–408.
  • Belmokhtar CA, Hillion J, Ségal-Bendirdjian E. Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms. Oncogene. 2001;20(26):3354–3362.
  • Qiao L, Koutsos M, Tsai LL, et al. Staurosporine inhibits the proliferation, alters the cell cycle distribution and induces apoptosis in HT-29 human colon adenocarcinoma cells. Cancer Lett. 1996;107(1):83–89.
  • Man SM, Kaakoush NO, Leach ST, et al. Host Attachment, Invasion, and Stimulation of Proinflammatory Cytokines by Campylobacter concisus and Other Non– campylobacter jejuni Campylobacter Species. J Infect Dis. 2010;202(12):1855–1865.
  • Remick DG. Interleukin-8. Crit Care Med. 2005;33(12):S466-S467.
  • Suzuki M, Hisamatsu T, Podolsky DK. Gamma interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular Toll-like receptor 4-MD-2 complex. Infect Immun. 2003;71(6):3503–3511.