Pilot study on selective antimicrobial effect of a halitosis mouthrinse: monospecies and saliva-derived microbiome in an in vitro model system

References

• Renvert S, Noack MJ, Lequart C, et al. The underestimated poblem of intra-oral halitosis in dental practice: an expert consensus review. Clin Cosmet Investig Dent. 2020;12:251–9.
   PubMed Web of Science ®Google Scholar
• Bollen CM, Beikler T. Halitosis: the multidisciplinary approach. Int J Oral Sci. 2012;4(2):55–63.
   PubMed Web of Science ®Google Scholar
• Kapoor U, Sharma G, Juneja M, et al. Halitosis: current concepts on etiology, diagnosis and management. Eur J Dent. 2016;10(2):292–300.
   Google Scholar
• Silva MF, Leite FRM, Ferreira LB, et al. Estimated prevalence of halitosis: a systematic review and meta-regression analysis. Clin Oral Investig. 2018;22(1):47–55.
   PubMed Web of Science ®Google Scholar
• Campisi G, Musciotto A, Di Fede O, et al. Halitosis: could it be more than mere bad breath? Intern Emerg Med. 2011;6(4):315–319.
   PubMed Web of Science ®Google Scholar
• Koshimune S, Awano S, Gohara K, et al. Low salivary flow and volatile sulfur compounds in mouth air. Oral Surg Oral Med O. 2003;96(1):38–41.
   Web of Science ®Google Scholar
• Morita M, Wang HL. Association between oral malodor and adult periodontitis: a review. J Clin Periodontol. 2001;28(9):813–819.
   PubMed Web of Science ®Google Scholar
• Dewhirst FE, Chen T, Izard J, et al. The human oral microbiome. J Bacteriol. 2010;192(19):5002–5017.
   PubMed Web of Science ®Google Scholar
• Amou T, Hinode D, Yoshioka M, et al. Relationship between halitosis and periodontal disease - associated oral bacteria in tongue coatings. Int J Dent Hyg. 2014;12(2):145–151.
   Web of Science ®Google Scholar
• Grover HS, Blaggana A, Jain Y, et al. Detection and measurement of oral malodor in chronic periodontitis patients and its correlation with levels of select oral anaerobes in subgingival plaque. Contemp Clin Dent. 2015;6(1):S181–7.
   Google Scholar
• Chukkapalli SS, Rivera-Kweh MF, Velsko IM, et al. Chronic oral infection with major periodontal bacteria Tannerella forsythia modulates systemic atherosclerosis risk factors and inflammatory markers. Patho Dis. 2015;73(3):3.
   Google Scholar
• Porter SR, Scully C. Oral malodour (halitosis). Bmj-Brit Med J. 2006;333(7569):632–635.
   Web of Science ®Google Scholar
• Donaldson AC, McKenzie D, Riggio MP, et al. Microbiological culture analysis of the tongue anaerobic microflora in subjects with and without halitosis. Oral Dis. 2005;11(Suppl 1):61–63.
   PubMedGoogle Scholar
• Awano S, Gohara K, Kurihara E, et al. The relationship between the presence of periodontopathogenic bacteria in saliva and halitosis. Int Dent J. 2002;52(5):212–216.
   Google Scholar
• Apatzidou AD, Bakirtzoglou E, Vouros I, et al. Association between oral malodour and periodontal disease-related parameters in the general population. Acta Odontol Scand. 2013;71(1):189–195.
   PubMed Web of Science ®Google Scholar
• Persson S, Edlund MB, Claesson R, et al. The formation of hydrogen-sulfide and methyl mercaptan by oral bacteria. Oral Microbiol Immun. 1990;5(4):195–201.
   PubMedGoogle Scholar
• Takeshita T, Suzuki N, Nakano Y, et al.Discrimination of the oral microbiota associated with high hydrogen sulfide and methyl mercaptan production. Sci Rep. 2012;2:215.
   Google Scholar
• Hampelska K, Jaworska MM, Babalska ZL, et al. The role of oral microbiota in intra-oral halitosis. J Clin Med. 2020;9(8):8.
   Web of Science ®Google Scholar
• Foo LH, Balan P, Pang LM, et al. Role of the oral microbiome, metabolic pathways, and novel diagnostic tools in intra-oral halitosis: a comprehensive update. Crit Rev Microbiol. 2021;47(3):359–375.
   PubMed Web of Science ®Google Scholar
• Fine DH. Listerine: past, present and future - A test of thyme. J Dent. 2010;38:S2–S5.
   Web of Science ®Google Scholar
• Bescos R, Ashworth A, Cutler C, et al. Effects of Chlorhexidine mouthwash on the oral microbiome. Sci Rep. 2020;10(1):5254.
   PubMed Web of Science ®Google Scholar
• Roldan S, Winkel EG, Herrera D, et al. The effects of a new mouthrinse containing chlorhexidine, cetylpyridinium chloride and zinc lactate on the microflora of oral halitosis patients: a dual-centre, double-blind placebo-controlled study. J Clin Periodontol. 2003;30(5):427–434.
   PubMed Web of Science ®Google Scholar
• Agnello M, Cen L, Tran NC, et al. Arginine improves pH homeostasis via metabolism and microbiome modulation. J Dent Res. 2017;96(8):924–930.
   PubMed Web of Science ®Google Scholar
• Tian Y, He X, Torralba M, et al. Using DGGE profiling to develop a novel culture medium suitable for oral microbial communities. Mol Oral Microbiol. 2010;25(5):357–367.
   Web of Science ®Google Scholar
• Caporaso JG, Kuczynski J, Stombaugh J, et al. QIIME allows analysis of high-throughput community sequencing data. Nat Methods. 2010;7(5):335–336.
   PubMed Web of Science ®Google Scholar
• Edgar RC. Search and clustering orders of magnitude faster than BLAST. Bioinformatics. 2010;26(19):2460–2461.
   PubMed Web of Science ®Google Scholar
• Chen T, Yu W-H, Izard J, et al. The human oral microbiome database: a web accessible resource for investigating oral microbe taxonomic and genomic information. Database. 2010;baq013.
   Google Scholar
• Edlund A, Yang Y, Hall AP, et al. An in vitro biofilm model system maintaining a highly reproducible species and metabolic diversity approaching that of the human oral microbiome. Microbiome. 2013;1(1):25.
   Google Scholar
• Baker JL, Bor B, Agnello M, et al. Ecology of the oral microbiome: beyond bacteria. Trends Microbiol. 2017;25(5):362–374.
   PubMed Web of Science ®Google Scholar
• ADA Council on Scientif Affairs. Oral malodor. J Am Dent Assoc. 2003;134(2):209–214.
   Web of Science ®Google Scholar
• Slot DE, De Geest S, Van Der Weijden FA, et al. Treatment of oral malodour. Medium-term efficacy of mechanical and/or chemical agents: a systematic review. J Clin Periodontol. 2015;42(Suppl 16):S303–16.
   Google Scholar
• Abranches J, Zeng L, Kajfasz JK, et al. Biology of oral Streptococci. Microbiol Spectr. 2018;6(5):5.
   Web of Science ®Google Scholar
• Zhu B, Macleod LC, Kitten T, et al. Streptococcus sanguinis biofilm formation & interaction with oral pathogens. Future Microbiol. 2018;13(8):915–932.
   PubMed Web of Science ®Google Scholar
• Sterer N, Rosenberg M. Streptococcus salivarius promotes mucin putrefaction and malodor production by Porphyromonas gingivalis. J Dent Res. 2006;85(10):910–914.
   PubMed Web of Science ®Google Scholar
• Mineoka T, Awano S, Rikimaru T, et al. Site-specific development of periodontal disease is associated with increased levels of Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia in subgingival plaque. J Periodontol. 2008;79(4):670–676.
   Web of Science ®Google Scholar
• Feres M, Figueiredo LC, Faveri M, et al. The efficacy of two oral hygiene regimens in reducing oral malodour: a randomised clinical trial. Int Dent J. 2015;65(6):292–302.
   Web of Science ®Google Scholar
• Henry LG, McKenzie RM, Robles A, et al. Oxidative stress resistance in Porphyromonas gingivalis. Future Microbiol. 2012;7(4):497–512.
   PubMed Web of Science ®Google Scholar
• Yamamoto Y, Higuchi M, Poole LB, et al. Role of the dpr product in oxygen tolerance in Streptococcus mutans. J Bacteriol. 2000;182(13):3740–3747.
   Web of Science ®Google Scholar
• Frohner IE, Bourgeois C, Yatsyk K, et al. Candida albicans cell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance. Mol Microbiol. 2009;71(1):240–252.
   PubMed Web of Science ®Google Scholar
• Suzuki N, Yoneda M, Takeshita T, et al. Induction and inhibition of oral malodor. Mol Oral Microbiol. 2019;34(3):85–96.
   Web of Science ®Google Scholar
• Loesche WJ. Role of Streptococcus mutans in human dental decay. Microbiolo Rev. 1986;50(4):353–380.
   PubMedGoogle Scholar
• Barbeau J, Séguin J, Goulet JP, et al. Reassessing the presence of Candida albicans in denture-related stomatitis. Oral Surg Oral Med OralPathol Oral Radiol Endod. 2003;95(1):51–59.
   PubMed Web of Science ®Google Scholar