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Journal of Plastic Surgery and Hand Surgery Volume 53, 2019 - Issue 5
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Articles

The beneficial effects of subcutaneous Allium cepa injection on random flap survival in rats

Dinçer AltınelDepartment of Plastic and Reconstructive Surgery, Istanbul Training and Research Hospital, University of Health Sciences, Istanbul, Turkey;
,
Merdan SerinDepartment of Plastic and Reconstructive Surgery, Istanbul Training and Research Hospital, University of Health Sciences, Istanbul, Turkey; Correspondence[email protected]
,
Havva ErdemDepartment of Pathology, Ordu University Training and Research Hospital, Ordu, Turkey;
,
Burcu BiltekinDepartment of Histology and Embryology, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey;
,
Mert CeliktenAnimal Research Laboratory, Bezmialem University Medical School, Istanbul, Turkey;
,
Sevgi Kurt YazarDepartment of Plastic and Reconstructive Surgery, Istanbul Training and Research Hospital, University of Health Sciences, Istanbul, Turkey;
,
Gaye TopluDepartment of Plastic and Reconstructive Surgery, Istanbul Training and Research Hospital, University of Health Sciences, Istanbul, Turkey;
&
Eymen OrucDepartment of Otorhinolaryngology, Istanbul State Hospital, Catalca, Turkey
 show all
Pages 260-264 | Received 16 Nov 2018, Accepted 12 Mar 2019, Published online: 23 Apr 2019

References

  • Kaur G, Gupta V, Christopher AF, et al. Kitchen phytochemicals from Allium cepa - their role in multidrug resistance. Pak J Pharm Sci. 2017;30:789–792.
  • Block E. The chemistry of garlic and onions. Sci Am. 1985;252:114–119.
  • Dorsch W, Schneider E, Bayer T, et al. Anti-inflammatory effects of onions: inhibition of chemotaxis of human polymorphonuclear leukocytes by thiosulfinates and cepaenes. Int Arch Allergy Immunol. 1990;92:39–42.
  • Zohri AN, Abdel-Gawad K, Saber S. Antibacterial, antidermatophytic and antitoxigenic activities of onion (Allium cepa L.) oil. Microbiol Res. 1995;150:167–172.
  • Nicastro HL, Ross SA, Milner JA. Garlic and onions: their cancer prevention properties. Cancer Prev Res (Phila). 2015;8:181–189.
  • Farbman KS, Barnett ED, Bolduc GR, et al. Antibacterial activity of garlic and onions a historical perspective. Pediatr Infect Dis J. 1993;12:613–614.
  • Draelos ZD. The ability of onion extract gel to improve the cosmetic appearance of postsurgical scars. J Cosmet Dermatol. 2008;7:101–104.
  • Naseri MK, Arabian M, Badavi M, et al. Vasorelaxant and hypotensive effects of Allium cepa peel hydroalcoholic extract in rat. Pak J Biol Sci. 2008;11:1569–1575.
  • Hammond DC, Brooksher RD, Mann RJ, et al. The dorsal skin-flap model in the rat: factors influencing survival. Plast Reconstr Surg. 1993;91:316–321.
  • McFarlane RM, Deyoung G, Henry RA. The design of a pedicle flap in the rat to study necrosis and its prevention. Plast Reconstr Surg. 1965;35:177–182.
  • Quinodoz P, Quinodoz M, Nussbaum JL, et al. Barium sulphate and soft-tissue radiology: allying the old and the new for the investigation of animal cutaneous microcirculation. Br J Plast Surg. 2002;55:664–667.
  • Choi EY, Lee H, Woo JS, et al. Effect of onion peel extract on endothelial function and endothelial progenitor cells in overweight and obese individuals. Nutrition. 2015;31:1131–1135.
  • Williams RJ, Spencer JP, Rice-Evans C. Flavonoids: antioxidants or signalling molecules? Free Radic Biol Med. 2004;36:838–849.
  • Bagdas D, Cam Etoz B, Inan Ozturkoglu S, et al. Effects of systemic chlorogenic acid on random-pattern dorsal skin flap survival in diabetic rats. Biol Pharm Bull. 2014;37:361–370.
  • Bagdas D, Etoz BC, Gul Z, et al. Chlorogenic acid enhances abdominal skin flap survival based on epigastric artery in nondiabetic and diabetic rats. Ann Plast Surg. 2016;77:e21–e25.
  • Belman S, Solomon J, Segal A, et al. Inhibition of soybean lipoxygenase and mouse skin tumor promotion by onion and garlic components. J Biochem Toxicol. 1989;4:151–160.
  • Ali M. Mechanism by which garlic (Allium sativum) inhibits cyclooxygenase activity. Effect of raw versus boiled garlic extract on the synthesis of prostanoids. Prostaglandins Leukot Essent Fatty Acids. 1995;53:397–400.
  • Skolleborg KC, Samdal F. Effect of preoperative inflammation of the wound bed on survival of skin flaps in rats. Scand J Plast Reconstr Surg Hand Surg. 1993;27:167–171.
  • Liston SL. Nonbacterial inflammation as a means of enhancing skin flap survival. Laryngoscope. 1984;94:1075–1085.
  • Colic M, Savic M. Garlic extracts stimulate proliferation of rat lymphocytes in vitro by increasing IL-2 and IL-4 production. Immunopharmacol Immunotoxicol. 2000;22:163–181.

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