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Articles

Management of venous flap insufficiency: the role of low molecular weight heparin in salvage

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Pages 285-290 | Received 14 Apr 2021, Accepted 09 Aug 2021, Published online: 25 Aug 2021

References

  • Largo RD, Selber JC, Garvey PB, et al. Outcome analysis of free flap salvage in outpatients presenting with microvascular compromise. Plast Reconstr Surg. 2018;141(1):20e–27e.
  • Jose M, Varghese J, Babu A. Salvage of venous congestion using medicinal leeches for traumatic nasal flap. J Maxillofac Oral Surg. 2015;14(Suppl 1):251–254.
  • Chang EI, Chang EI, Soto-Miranda MA, et al. Comprehensive evaluation of risk factors and management of impending flap loss in 2138 breast free flaps. Ann Plast Surg. 2016;77(1):67–71.
  • Fujiwara M, Nagata T, Matsushita Y, et al. Delayed distally based sural flap with temporary venous supercharging. Microsurgery. 2013;33(7):534–538.
  • Chang EI, Zhang H, Liu J, et al. Analysis of risk factors for flap loss and salvage in free flap head and neck reconstruction. Head Neck. 2016;38(S1):E771–E775.
  • Akan IM, Yildirim S, Giderog˘Lu K. Salvage of flaps with venous congestion. Ann Plast Surg. 2001;46:456.
  • Nguyen MQ, Crosby MA, Skoracki RJ, et al. Outcomes of flap salvage with medicinal leech therapy. Microsurgery. 2012;32(5):351–357.
  • Azzopardi EA, Whitaker IS, Rozen WM, et al. Chemical and mechanical alternatives to leech therapy: a systematic review and critical appraisal. J Reconstr Microsurg. 2011;27(8):481–486.
  • Gampper TJ, Zhang F, Mofakhami NF, et al. Beneficial effect of hyperbaric oxygen on island flaps subjected to secondary venous ischemia. Microsurgery. 2002;22(2):49–52.
  • Casey WJ, Craft RO, Rebecca AM, et al. Intra-arterial tissue plasminogen activator: an effective adjunct following microsurgical venous thrombosis. Ann Plast Surg. 2007;59(5):520–525.
  • Pérez M, Sancho J, Ferrer C, et al. Management of flap venous congestion: the role of heparin local subcutaneous injection. J Plast Reconstr Aesthet Surg. 2014;67(1):48–55.
  • Lineaweaver WC, Hill MK, Buncke GM, et al. Aeromonas hydrophila infections following use of medicinal leeches in replantation and flap surgery. Ann Plast Surg. 1992;29(3):238–244.
  • Lozano DD, Stephenson LL, Zamboni WA. Effect of hyperbaric oxygen and medicinal leeching on survival of axial skin flaps subjected to total venous occlusion. Plast Reconstr Surg. 1999;104(4):1029–1032.
  • Serletti JM, Moran SL, Orland GS, et al. Urokinase protocol for free-flap salvage following prolonged venous thrombosis. Plast Reconstr Surg. 1998;102(6):1947–1953.
  • Chang EI, Mehrara BJ, Festekjian JH, et al. Vascular complications and microvascular free flap salvage: the role of thrombolytic agents. Microsurgery. 2011;31(7):505–509.
  • Miyawaki T, Jackson IT, Elmazar H, et al. The effect of low-molecular-weight heparin in the survival of a rabbit congested skin flap. Plast Reconstr Surg. 2002;109:1994–1999.
  • Iglesias M, Butrón P. Local subcutaneous heparin as treatment for venous insufficiency in replanted digits. Plast Reconstr Surg. 1999;103(6):1719–1724.
  • Whitaker IS, Oboumarzouk O, Rozen WM, et al. The efficacy of medicinal leeches in plastic and reconstructive surgery: a systematic review of 277 reported clinical cases. Microsurgery. 2012;32(3):240–250.
  • Robinson C. Artificial leech technique. Plast Reconstr Surg. 1998;102(5):1787–1788.
  • Cornejo A, Shammas RL, Poveromo LP, et al. Institutional outcomes of leech therapy for venous congestion in 87 patients. J Reconstr Microsurg. 2017;33(9):612–618.
  • Zhao X, Higgins KM, Enepekides D, et al. Medicinal leech therapy for venous congested flaps: case series and review of the literature. J Otolaryngol Head Neck Surg. 2009;38(2):E61–E64.
  • Ribuffo D, Chiummariello S, Cigna E, et al. Salvage of a free flap after late total thrombosis of the flap and revascularisation. Scand J Plast Reconstr Surg Hand Surg. 2004;38(1):50–52.
  • Tuncali D, Terzioglu A, Cigsar B, et al. The value of medical leeches in the treatment of class IIC ring avulsion injuries: report of 2 cases. J Hand Surg Am. 2004;29(5):943–946.
  • Frodel JL, Jr, Barth P, Wagner J. Salvage of partial facial soft tissue avulsions with medicinal leeches. Otolaryngol Head Neck Surg. 2004;131(6):934–939.
  • Abbott SL, Cheung WK, Janda JM. The genus aeromonas: biochemical characteristics, atypical reactions, and phenotypic identification schemes. J Clin Microbiol. 2003;41(6):2348–2357.
  • Hermansdorfer J, Lineaweaver W, Follansbee S, et al. Antibiotic sensitivities of Aeromonas hydrophila cultured from medicinal leeches. Br J Plast Surg. 1988;41(6):649–651.
  • Whitaker IS, Josty IC, Hawkins S, et al. Medicinal leeches and the microsurgeon: a four-year study, clinical series and risk benefit review. Microsurgery. 2011;31(4):281–287.
  • Vishwanath G. Hyperbaric oxygen therapy in free flap surgery: is it meaningful? Med J Armed Forces India. 2011;67(3):253–256.
  • Yii NW, Evans GR, Miller MJ, et al. Thrombolytic therapy: what is its role in free flap salvage? Ann Plast Surg. 2001;46(6):601–604.
  • Barnett GR, Taylor GI, Mutimer KL. The “chemical leech”: intra-replant subcutaneous heparin as an alternative to venous anastomosis. Report of three cases. Br J Plast Surg. 1989;42(5):556–558.
  • Caplin DA, Nathan CR, Couper SG. Salvage of TRAM flaps with compromised venous outflow. Plas Reconstr Surg. 2000;106:400–401.
  • Chung TL, Holton LH, 3rd, Silverman RP. The effect of fondaparinux versus enoxaparin in the survival of a congested skin flap in a rabbit model. Ann Plast Surg. 2006;56:312–315.

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