References

• Aguilera, M., Arias, B., Wichers, M., Barrantes-Vidal, N., Moya, J., Villa, H., … Fañanás, L. (2009). Early adversity and 5-HTT/BDNF genes: New evidence of gene-environment interactions on depressive symptoms in a general population. Psychological Medicine, 39(9), 1425–11.
   Web of Science ®Google Scholar
• Aktekin, M., Karaman, T., Senol, Y. Y., Erdem, S., Erengin, H., & Akaydin, M. (2001). Anxiety, depression and stressful life events among medical students: A prospective study in Antalya, Turkey. Medical Education, 35, 12–17.
   PubMed Web of Science ®Google Scholar
• Al-Hadethe, A., Hunt, N., Thomas, S., & Al-Qaysi, A. (2014). Prevalence of traumatic events and PTSD symptoms among secondary school students in Baghdad. European Journal of Psychotraumatology, 5, 1–5.
   Web of Science ®Google Scholar
• Altınbaş, G., Altınbaş, K., Gülöksüz, S. A., Gülöksüz, S., Aydemir, Ö., & Özgen, G. (2015). Temperament characteristics in patients with panic disorder and their first-degree relatives. Comprehensive Psychiatry. doi:10.1016/j.comppsych.2015.03.008
   Web of Science ®Google Scholar
• Angelucci, F., Ricci, V., Gelfo, F., Martinotti, G., Brunetti, M., Sepede, G., … Caltagirone, C. (2014). BDNF serum levels in subjects developing or not post-traumatic stress disorder after trauma exposure. Brain and Cognition, 84(1), 118–122.
   Web of Science ®Google Scholar
• Arias, B., Aguilera, M., Moya, J., Sáiz, P. A., Villa, H., Ibáñez, M. I., … Fañanás, L. (2012). The role of genetic variability in the SLC6A4, BDNF and GABRA6 genes in anxiety-related traits. Acta Psychiatrica Scandinavica, 125(3), 194–202.
   Web of Science ®Google Scholar
• Bath, K. G., & Lee, F. S. (2006). Variant BDNF (Val66Met) impact on brain structure and function. Cognitive, Affective & Behavioral Neuroscience, 6(1), 79–85. Retrieved from http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2735856&tool=pmcentrez&rendertype=abstract
   PubMed Web of Science ®Google Scholar
• Baumann, C., Klauke, B., Weber, H., Domschke, K., Zwanzger, P., Pauli, P., … Reif, A. (2013). The interaction of early life experiences with COMT val158met affects anxiety sensitivity. Genes, Brain, and Behavior, 12(8), 821–829.
   PubMed Web of Science ®Google Scholar
• Beevers, C. G., Wells, T. T., & McGeary, J. E. (2009). The BDNF Val66Met polymorphism is associated with rumination in healthy adults. Emotion, 9(4), 579–584.
   Web of Science ®Google Scholar
• Bernstein, D., & Fink, L. (1998). Childhood trauma questionnaire: A retrospective self-report manual. San Antonio, TX: The Psychological Corporation.
   Google Scholar
• Bernstein, D. P., Stein, J. A., Newcomb, M. D., Walker, E., Pogge, D., Ahluvalia, T., … Zule, W. (2003). Development and validation of a brief screening version of the childhood trauma questionnaire. Child Abuse & Neglect, 27(2), 169–190.
   PubMed Web of Science ®Google Scholar
• Broekman, B. F. P. (2011). Stress, vulnerability and resilience, a developmental approach. European Journal of Psychotraumatology, 2, 7229.
   Web of Science ®Google Scholar
• Carver, C. S., Johnson, S. L., Joormann, J., Lemoult, J., & Cuccaro, M. L. (2011). Childhood adversity interacts separately with 5-HTTLPR and BDNF to predict lifetime depression diagnosis. Journal of Affective Disorders, 132(1–2), 89–93.
   Web of Science ®Google Scholar
• Casey, B. J., Glatt, C. E., Tottenham, N., Soliman, F., Bath, K., Amso, D., … Lee, F. S. (2009). Brain-derived neurotrophic factor as a model system for examining gene by environment interactions across development. Neuroscience, 164(1), 108–120.
   Web of Science ®Google Scholar
• Chen, J., Li, X., & McGue, M. (2013). The interacting effect of the BDNF Val66Met polymorphism and stressful life events on adolescent depression is not an artifact of gene-environment correlation: Evidence from a longitudinal twin study. Journal of Child Psychology and Psychiatry and Allied Disciplines, 54(10), 1066–1073.
   Web of Science ®Google Scholar
• Chen, J., Yu, J., Liu, Y., Zhang, L., & Zhang, J. (2015). BDNF Val66Met, stress, and positive mothering: Differential susceptibility model of adolescent trait anxiety. Journal of Anxiety Disorders, 34, 68–75.
   Web of Science ®Google Scholar
• Chen, Z.-Y., Jing, D., Bath, K. G., Ieraci, A., Khan, T., Siao, C.-J., … Lee, F. S. (2006). Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science, 314(5796), 140–143.
   PubMed Web of Science ®Google Scholar
• Collishaw, S., Pickles, A., Messer, J., Rutter, M., Shearer, C., & Maughan, B. (2007). Resilience to adult psychopathology following childhood maltreatment: Evidence from a community sample. Child Abuse & Neglect, 31(3), 211–229.
   PubMed Web of Science ®Google Scholar
• Dalvie, S., Stein, D. J., Koenen, K., Cardenas, V., Cuzen, N. L., Ramesar, R., … Brooks, S. J. (2014). The BDNF p.Val66Met polymorphism, childhood trauma, and brain volumes in adolescents with alcohol abuse. BMC Psychiatry, 14(1), 1–8.
   Google Scholar
• De Bellis, M. D., Woolley, D. P., & Hooper, S. R. (2013). Neuropsychological findings in pediatric maltreatment: Relationship of PTSD, dissociative symptoms, and abuse/neglect indices to neurocognitive outcomes. Child Maltreatment, 18(3), 171–183.
   PubMed Web of Science ®Google Scholar
• Duncan, L. E., & Keller, M. C. (2011). A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry. American Journal of Psychiatry, 168(10), 1041–1049.
   PubMed Web of Science ®Google Scholar
• Dvir, Y., Ford, J. D., Hill, M., & Frazier, J. A. (2014). Childhood maltreatment, emotional dysregulation, and psychiatric comorbidities. Harvard Review of Psychiatry, 22(3), 149–161.
   PubMed Web of Science ®Google Scholar
• Egan, M. F., Kojima, M., Callicott, J. H., Goldberg, T. E., Kolachana, B. S., Bertolino, A., … Weinberger, D. R. (2003). The BDNF Val66Met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell, 112(2), 257–269. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/12553913
   PubMed Web of Science ®Google Scholar
• Eley, T. C., Gregory, A. M., Clark, D. M., & Ehlers, A. (2007). Feeling anxious: A twin study of panic/somatic ratings, anxiety sensitivity and heartbeat perception in children. Journal of Child Psychology and Psychiatry, 48(12), 1184–1191.
   Web of Science ®Google Scholar
• Elzinga, B. M., Molendijk, M. L., Oude Voshaar, R. C., Bus, B. A. A., Prickaerts, J., Spinhoven, P., & Penninx, B. J. W. H. (2011). The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val 66Met. Psychopharmacology, 214(1), 319–328.
   Web of Science ®Google Scholar
• Eysenck, M. (1992). Anxiety: The cognitive perspective. Hove: Lawrence Erbaum.
   Google Scholar
• Figurov, A., Pozzo-Miller, L. D., Olafsson, P., Wang, T., & Lu, B. (1996). Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature, 381(6584), 706–709.
   PubMed Web of Science ®Google Scholar
• Frustaci, A., Pozzi, G., Gianfagna, F., Manzoli, L., & Boccia, S. (2008). Meta-analysis of the brain-derived neurotrophic factor gene (BDNF) Val66Met polymorphism in anxiety disorders and anxiety-related personality traits. Neuropsychobiology, 58(3–4), 163–170.
   PubMed Web of Science ®Google Scholar
• Garcia, S. E., Tully, E. C., Tarantino, N., South, S., Jacono, W. G., & McGue, M. (2013). Changes in genetic and environmental influences on trait anxiety from middle adolescence to early adulthood. Journal of Affective Disorders, 151(1), 46–53.
   Web of Science ®Google Scholar
• Gatt, J. M., Nemeroff, C. B., Dobson-Stone, C., Paul, R. H., Bryant, R. A., Schofield, P. R., … Williams, L. M. (2009). Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety. Molecular Psychiatry, 14(7), 681–695.
   PubMed Web of Science ®Google Scholar
• González, J. R., Armengol, L., Solé, X., Guinó, E., Mercader, J. M., Estivill, X., & Moreno, V. (2007). SNPassoc: An R package to perform whole genome association studies. Bioinformatics, 23(5), 644–645.
   PubMed Web of Science ®Google Scholar
• Greger, H. K., Myhre, A. K., Lydersen, S., & Jozefiak, T. (2015). Previous maltreatment and present mental health in a high-risk adolescent population. Child Abuse and Neglect, 45, 122–134.
   PubMed Web of Science ®Google Scholar
• Gunthert, K. C., Conner, T. S., Armeli, S., Tennen, H., Covault, J., & Kranzler, H. R. (2007). Serotonin transporter gene polymorphism (5-HTTLPR) and anxiety reactivity in daily life: A daily process approach to gene-environment interaction. Psychosomatic Medicine, 69(8), 762–768.
   Web of Science ®Google Scholar
• Gutiérrez, B., Bellón, J. Á., Rivera, M., Molina, E., King, M., Marston, L., … Cervilla, J. (2015). The risk for major depression conferred by childhood maltreatment is multiplied by BDNF and SERT genetic vulnerability: A replication study. Journal of Psychiatry and Neuroscience, 40(3), 187–196.
   Web of Science ®Google Scholar
• Hariri, A. R., Goldberg, T. E., Mattay, V. S., Kolachana, B. S., Callicott, J. H., Egan, M. F., & Weinberger, D. R. (2003). Brain-derived neurotrophic factor Val66Met polymorphism affects human memory-related hippocampal activity and predicts memory performance. The Journal of Neuroscience, 23(17), 6690–6694.
   PubMed Web of Science ®Google Scholar
• Hayward, C., Killen, J. D., Kraemer, H. C., & Taylor, C. B. (2000, March). Predictors of panic attacks in adolescents. Journal of the American Academy of Child and Adolescent Psychiatry. doi:10.1097/00004583-200002000-00021
   Web of Science ®Google Scholar
• Hemmings, S. M. J., Kinnear, C. J., van der Merwe, L., Lochner, C., Corfield, V. A., Moolman-Smook, J. C., & Stein, D. J. (2008). Investigating the role of the brain-derived neurotrophic factor (BDNF) Val66Met variant in obsessive-compulsive disorder (OCD). The World Journal of Biological Psychiatry, 9(2), 82–85.
   Web of Science ®Google Scholar
• Hemmings, S. M. J., Martin, L. I., van der Merwe, L., Benecke, R., Domschke, K., & Seedat, S. (2016). Serotonin transporter variants play a role in anxiety sensitivity in South African adolescents. The World Journal of Biological Psychiatry, 17(1), 66–75.
   PubMed Web of Science ®Google Scholar
• Hiio, K., Merenäkk, L., Nordquist, N., Parik, J., Oreland, L., Veidebaum, T., & Harro, J. (2011). Effects of serotonin transporter promoter and BDNF Val66Met genotype on personality traits in a population representative sample of adolescents. Psychiatric Genetics, 21(5), 261–264.
   Web of Science ®Google Scholar
• Hishinuma, E. S., Miyamoto, R. H., Nishimura, S. T., Goebert, D. A., Yuen, N. Y., Makini, G. K., … Carlton, B. S. (2001). Prediction of anxiety disorders using the state–trait anxiety inventory for multiethnic adolescents. Journal of Anxiety Disorders, 15(6), 511–533.
   Web of Science ®Google Scholar
• Hofer, M., Pagliusi, S. R., Hohn, A., Leibrock, J., & Barde, Y.-A. (1990). Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. EMBO Journal, 9(8), 2459–2464.
   PubMed Web of Science ®Google Scholar
• Hong, C. J., Liou, Y. J., & Tsai, S. J. (2012). Effects of BDNF polymorphisms on brain function and behavior in health and disease. Brain Research Bulletin, 88(5), 406–417.
   Web of Science ®Google Scholar
• Hosang, G. M., Shiles, C., Tansey, K. E., McGuffin, P., & Uher, R. (2014). Interaction between stress and the BDNF Val66Met polymorphism in depression: A systematic review and meta-analysis. BMC Medicine, 12(1), 7.
   PubMedGoogle Scholar
• Huang, E. J., & Reichardt, L. F. (2001). Neurotrophins: Roles in neuronal development and function. Annual Review of Neuroscience, 24, 677–736.
   PubMed Web of Science ®Google Scholar
• Ibarra, P., Alemany, S., Fatjó-Vilas, M., Córdova-Palomera, A., Goldberg, X., Arias, B., … Fañanás, L. (2014). The BDNF-Val66Met polymorphism modulates parental rearing effects on adult psychiatric symptoms: A community twin-based study. European Psychiatry, 29(5), 293–300.
   Web of Science ®Google Scholar
• Irigaray, T. Q., Pacheco, J. B., Grassi-Oliveira, R., Fonseca, R. P., de Carvalho Leite, J. C., & Kristensen, C. H. (2013). Child maltreatment and later cognitive functioning: A systematic review. Psicologia: Reflexao E Critica, 26(2), 376–382. Retrieved from www.scielo.br/prc
   Web of Science ®Google Scholar
• Kaufman, J., Yang, B. Z., Douglas-Palumberi, H., Grasso, D., Lipschitz, D., Houshyar, S., … Gelernter, J. (2006). Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children. Biological Psychiatry, 59(8), 673–680.
   PubMed Web of Science ®Google Scholar
• Keeley, M. L., & Storch, E. A. (2009). Anxiety disorders in youth. Journal of Pediatric Nursing, 24(1), 26–40.
   PubMedGoogle Scholar
• Kessler, R. C., McLaughlin, K. A., Green, J. G., Gruber, M. J., Sampson, N. A., Zaslavsky, A. M., … Williams, D. R. (2010). Childhood adversities and adult psychopathology in the WHO world mental health surveys. British Journal of Psychiatry, 197(5), 378–385.
   PubMed Web of Science ®Google Scholar
• Kim, S. J., Cho, S. J., Jang, H. M., Shin, J., Park, P. W., Lee, Y. J., … Lee, H. J. (2009). Interaction between brain-derived neurotrophic factor Val66Met polymorphism and recent negative stressor in harm avoidance. Neuropsychobiology, 61(1), 19–26.
   Web of Science ®Google Scholar
• Klauke, B., Deckert, J., Reif, A., Pauli, P., Zwanzger, P., Baumann, C., … Domschke, K. (2011). Serotonin transporter gene and childhood trauma - A G × E effect on anxiety sensitivity. Depression and Anxiety, 28(12), 1048–1057.
   Web of Science ®Google Scholar
• Lam, P., Cheng, C.-Y., Hong, C. J., & Tsai, S.-J. (2004). Association study of a brain-derived neurotrophic factor (Val66Met) genetic polymorphism and panic disorder. Neuropsychobiology, 49(4), 178–181.
   Web of Science ®Google Scholar
• Lang, U. E., Hellweg, R., Kalus, P., Bajbouj, M., Lenzen, K. P., Sander, T., … Gallinat, J. (2005). Association of a functional BDNF polymorphism and anxiety-related personality traits. Psychopharmacology, 180(1), 95–99.
   PubMed Web of Science ®Google Scholar
• Lau, J. Y. F., Gregory, A. M., Goldwin, M. A., Pine, D. S., & Eley, T. (2007). Assessing gene-environment interactions on anxiety symptom subtypes across childhood and adolescence. Development and Psychopathology, 19(4), 1129–1146.
   Web of Science ®Google Scholar
• Laucht, M., Treutlein, J., Blomeyer, D., Buchmann, A. F., Schmid, B., Becker, K., … Banaschewski, T. (2009). Interaction between the 5-HTTLPR serotonin transporter polymorphism and environmental adversity for mood and anxiety psychopathology: Evidence from a high-risk community sample of young adults. The International Journal of Neuropsychopharmacology, 12(6), 737–747.
   Web of Science ®Google Scholar
• Lehto, K., Maestu, J., Kiive, E., Veidebaum, T., & Harro, J. (2016). BDNF Val66Met genotype and neuroticism predict life stress: A longitudinal study from childhood to adulthood. European Neuropsychopharmacology, 26(3), 562–569.
   Web of Science ®Google Scholar
• Li, M., Chang, H., & Xiao, X. (2016). BDNF Val66Met polymorphism and bipolar disorder in European populations: A risk association in case-control, family-based and GWAS studies. Neuroscience & Biobehavioral Reviews, 68, 218–233.
   PubMed Web of Science ®Google Scholar
• Mandelman, S. D., & Grigorenko, E. L. (2012). BDNF Val66Met and cognition: All, none, or some? A meta-analysis of the genetic association. Genes, Brain and Behavior, 11(2), 127–136.
   PubMed Web of Science ®Google Scholar
• Martin, L, Viljoen, M, Kidd, M, & Seedat, S. (2014). Are Childhood Trauma Exposures Predictive Of Anxiety Sensitivity in School Attending Youth? Journal Of Affective Disorders, 168, 5-12.
   Google Scholar
• Martinowich, K., & Lu, B. (2008). Interaction between BDNF and serotonin: Role in mood disorders. Neuropsychopharmacology, 33(1), 73–83.
   PubMed Web of Science ®Google Scholar
• Martinowich, K., Manji, H., & Lu, B. (2007). New insights into BDNF function in depression and anxiety. Nature Neuroscience, 10(9), 1089–1093.
   PubMed Web of Science ®Google Scholar
• McLaughlin, E. N., Stewart, S. H., & Taylor, S. (2007). Childhood anxiety sensitivity index factors predict unique variance in DSM-IV anxiety disorder symptoms. Cognitive Behaviour Therapy, 36(4), 210–219.
   PubMedGoogle Scholar
• McLaughlin, K. A., Green, J. G., Gruber, M. J., Sampson, N. A., Zaslavsky, A. M., & Kessler, R. C. (2012). Childhood adversities and first onset of psychiatric disorders in a national sample of US adolescents. JAMA Psychiatry, 69(11), 1151–1160. Retrieved from http://libezproxy.open.ac.uk/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=psyh&AN=2013-03085-007&site=ehost-live&scope=site&scope=cite
   Google Scholar
• McLaughlin, K. A., & Hatzenbuehler, M. L. (2009). Stressful life events, anxiety sensitivity, and internalizing symptoms in adolescents. Journal of Abnormal Psychology, 118(3), 659–669.
   PubMed Web of Science ®Google Scholar
• Min, J. A., Lee, H. J., Lee, S. H., Park, Y. M., Kang, S. G., & Chae, J. H. (2013). Gender-specific effects of brain-derived neurotrophic factor Val66Met polymorphism and childhood maltreatment on anxiety. Neuropsychobiology, 67(1), 6–13.
   Web of Science ®Google Scholar
• Minelli, A., Zanardini, R., Bonvicini, C., Sartori, R., Pedrini, L., Gennarelli, M., & Bocchio-Chiavetto, L. (2011). BDNF serum levels, but not BDNF Val66Met genotype, are correlated with personality traits in healthy subjects. European Archives of Psychiatry and Clinical Neuroscience, 261(5), 323–329.
   Web of Science ®Google Scholar
• Mitoma, M., Yoshimura, R., Sugita, A., Umene, W., Hori, H., Nakano, H., … Nakamura, J. (2008). Stress at work alters serum brain-derived neurotrophic factor (BDNF) levels and plasma 3-methoxy-4-hydroxyphenylglycol (MHPG) levels in healthy volunteers: BDNF and MHPG as possible biological markers of mental stress? Progress in Neuro-Psychopharmacology and Biological Psychiatry, 32(3), 679–685.
   Web of Science ®Google Scholar
• Molendijk, M. L., Spinhoven, P., Polak, M., Bus, B. A. A., Penninx, B. W. J. H., & Elzinga, B. M. (2014). Serum BDNF concentrations as peripheral manifestations of depression: Evidence from a systematic review and meta-analyses on 179 associations (N=9484). Molecular Psychiatry, 19(7), 791–800.
   PubMed Web of Science ®Google Scholar
• Montag, C., Basten, U., Stelzel, C., Fiebach, C. J., & Reuter, M. (2010). The BDNF Val66Met polymorphism and anxiety: Support for animal knock-in studies from a genetic association study in humans. Psychiatry Research, 179(1), 86–90.
   Web of Science ®Google Scholar
• Murakami, S., Imbe, H., Morikawa, Y., Kubo, C., & Senba, E. (2005). Chronic stress, as well as acute stress, reduces BDNF mRNA expression in the rat hippocampus but less robustly. Neuroscience Research, 53(2), 129–139.
   PubMed Web of Science ®Google Scholar
• Muris, P., Schmidt, H., Merckelbach, H., & Schouten, E. (2001). Anxiety sensitivity in adolescents: Factor structure and relationships to trait anxiety and symptoms of anxiety disorders and depression. Behaviour Research and Therapy, 39(1), 89–100. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/11125726
   PubMed Web of Science ®Google Scholar
• Nedic, G., Nikolac Perkovic, M., Nenadic Sviglin, K., Muck-Seler, D., Borovecki, F., & Pivac, N. (2013). Brain-derived neurotrophic factor Val66Met polymorphism and alcohol-related phenotypes. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 40(1), 193–198.
   Google Scholar
• Nordanger, D. O., Breivik, K., Haugland, B. S., Lehman, S., Mæhle, M., Braarud, H. C., & Hysing, M. (2014). Prior adversities predict posttraumatic stress reactions in adolescents following the Oslo Terror events 2011. European Journal of Psychotraumatology, 5, 23159.
   Web of Science ®Google Scholar
• Notaras, M., Hill, R., & van den Buuse, M. (2015). The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: Progress and controversy. Molecular Psychiatry, 20(8), 916–930.
   PubMed Web of Science ®Google Scholar
• Petryshen, T. L., Sabeti, P. C., Aldinger, K. A., Fry, B., Fan, J. B., Schaffner, S. F., … Sklar, P. (2009). Population genetic study of the brain-derived neurotrophic factor (BDNF) gene. Molecular Psychiatry, 15(8), 1–6.
   Web of Science ®Google Scholar
• Pezawas, L., Meyer-Lindenberg, A., Goldman, A. L., Verchinski, B. A., Chen, G., Kolachana, B. S., … Weinberger, D. R. (2008). Evidence of biologic epistasis between BDNF and SLC6A4 and implications for depression. Molecular Psychiatry, 13(7), 709–716.
   PubMed Web of Science ®Google Scholar
• Pivac, N., Kim, B., Nedić, G., Joo, Y. H., Kozarić-Kovacić, D., Hong, J. P., & Muck-Seler, D. (2009). Ethnic differences in brain-derived neurotrophic factor Val66Met polymorphism in Croatian and Korean healthy participants. Croatian Medical Journal, 50(1), 43–48.
   Web of Science ®Google Scholar
• Reiss, S., & McNally, R. (1985). Expectancy model of fear. In S. Reiss & R. R. Bootzin (Eds.), Theoretical issues in behavior therapy (pp. 107–121). San Diego, CA: Academic Press.
   Google Scholar
• Reiss, S., Peterson, R. A., Gursky, D. M., & McNally, R. J. (1986). Anxiety sensitivity, anxiety frequency and the prediction of fearfulness. Behaviour Research and Therapy, 24(1), 1–8. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/3947307
   PubMed Web of Science ®Google Scholar
• Scher, C. D., & Stein, M. B. (2003). Developmental antecedents of anxiety sensitivity. Journal of Anxiety Disorders, 17(3), 253–269. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/12727121
   PubMed Web of Science ®Google Scholar
• Schiele, M. A., Ziegler, C., Holitschke, K., Schartner, C., Schmidt, B., Weber, H., … Domschke, K. (2016). Influence of 5-HTT variation, childhood trauma and self-efficacy on anxiety traits: A gene-environment-coping interaction study. Journal of Neural Transmission, 123(8), 895–904.
   PubMed Web of Science ®Google Scholar
• Schmidt, N., Zvolensky, M., & Maner, J. (2006). Anxiety sensitivity: Prospective prediction of panic attacks and Axis I pathology. Journal of Psychiatric Research, 40(8), 691–699.
   PubMed Web of Science ®Google Scholar
• Schmidt, N. B., Keough, M. E., Mitchell, M. A., Reynolds, E. K., Macpherson, L., Zvolensky, M. J., & Lejuez, C. W. (2010). Anxiety sensitivity: Prospective prediction of anxiety among early adolescents. Journal of Anxiety Disorders, 24(5), 503–508.
   PubMed Web of Science ®Google Scholar
• Sen, S., Nesse, R. M., Stoltenberg, S. F., Li, S., Gleiberman, L., Chakravarti, A., … Burmeister, M. (2003). A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression. Neuropsychopharmacology, 28(2), 397–401.
   PubMed Web of Science ®Google Scholar
• Silverman, W. K, Fleisig, W, Rabian, B, & Peterson, R. A. (1991). Childhood anxiety sensitivity index. Journal of Clinical Child and adolescent Psychology, 20(2), 162–168. doi:
   Web of Science ®Google Scholar
• Simmons, A., Strigo, I., Matthews, S. C., Paulus, M. P., & Stein, M. B. (2006). Anticipation of aversive visual stimuli is associated with increased insula activation in anxiety-prone subjects. Biological Psychiatry, 60(4), 402–409.
   PubMed Web of Science ®Google Scholar
• Şimşek, Ş., Yüksel, T., Kaplan, I., Uysal, C., & Alaca, R. (2015). Examining the levels of BDNF and cortisol in children and adolescent victims of sexual abuse - a preliminary study. Comprehensive Psychiatry, 61(2015), 23–27.
   Google Scholar
• StatSoftInc. (2015). STATISTICA version 13. Tulsa, OK: StatSoftInc.
   Google Scholar
• Stein, M. B., Jang, K. L., & Livesley, W. J. (1999). Heritability of anxiety sensitivity: A twin study. The American Journal of Psychiatry, 156(2), 246–251. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/9989561
   PubMed Web of Science ®Google Scholar
• Stein, M. B., Schork, N. J., & Gelernter, J. (2008). Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders. Neuropsychopharmacology, 33(2), 312–319.
   PubMed Web of Science ®Google Scholar
• Suliman, S., Hemmings, S. M. J., & Seedat, S. (2013). Brain-derived neurotrophic factor (BDNF) protein levels in anxiety disorders: Systematic review and meta-regression analysis. Frontiers in Integrative Neuroscience, 7(July), 55.
   Google Scholar
• Surtees, P., Wainwright, N., Willis-Owen, S., Sandhu, M., Luben, R., Day, N., & Flint, J. (2007). No association between the BDNF Val66Met polymorphism and mood status in a non-clinical community sample of 7389 older adults. Journal of Psychiatric Research, 41(5), 404–409.
   Web of Science ®Google Scholar
• Suzuki, G., Tokuno, S., Nibuya, M., Ishida, T., Yamamoto, T., Mukai, Y., … Shimizu, K. (2014). Decreased plasma brain-derived neurotrophic factor and vascular endothelial growth factor concentrations during military training. PLoS ONE, 9(2), 1–9.
   Web of Science ®Google Scholar
• Szentágotai-Tətar, A., Chis, A., Vulturar, R., Dobrean, A., Cândea, D. M., & Miu, A. C. (2015). Shame and guilt-proneness in adolescents: Gene-environment interactions. PLoS One, 10(7), 1–16.
   Web of Science ®Google Scholar
• Taillieu, T. L., Brownridge, D. A., Sareen, J., & Afifi, T. O. (2016). Childhood emotional maltreatment and mental disorders: Results from a nationally representative adult sample from the United States. Child Abuse and Neglect, 59, 1–12.
   PubMed Web of Science ®Google Scholar
• Teicher, M., Ohashi, K., Lowen, S., Polcari, A., & Fitzmaurice, G. (2015). Mood dysregulation and affective instability in emerging adults with childhood maltreatment: An ecological momentary assessment study. Journal of Psychiatric Research, 70, 1–8.
   PubMed Web of Science ®Google Scholar
• Terracciano, A., Tanaka, T., Sutin, A. R., Deiana, B., Balaci, L., Sanna, S., … Costa, P. T. (2010). BDNF Val66Met is associated with introversion and interacts with 5-HTTLPR to influence neuroticism. Neuropsychopharmacology, 35(5), 1083–1089.
   PubMed Web of Science ®Google Scholar
• Tishkoff, S. A., Reed, F. A., Friedlaender, F. R., Ranciaro, A., Froment, A., Hirbo, J. B., … Williams, S. M. (2009). The genetic structure and history of Africans and African Americans. Science, 324(5930), 1035–1044.
   PubMed Web of Science ®Google Scholar
• Tocchetto, A., Salum, G. A., Blaya, C., Teche, S., Isolan, L., Bortoluzzi, A., … Manfro, G. G. (2011). Evidence of association between Val66Met polymorphism at BDNF gene and anxiety disorders in a community sample of children and adolescents. Neuroscience Letters, 502(3), 197–200.
   Web of Science ®Google Scholar
• Tollenaar, M. S., Molendijk, M. L., Penninx, B. W. J. H., Milaneschi, Y., & Antypa, N. (2017). The association of childhood maltreatment with depression and anxiety is not moderated by the oxytocin receptor gene. European Archives of Psychiatry and Clinical Neurosciences, 267, 517–526.
   Web of Science ®Google Scholar
• Vendlinski, M. K., Lemery-Chalfant, K., Essex, M. J., & Goldsmith, H. H. (2011). Genetic risk by experience interaction for childhood internalizing problems: Converging evidence across multiple methods. Journal of Child Psychology and Psychiatry and Allied Disciplines, 52(5), 607–618.
   Web of Science ®Google Scholar
• Wang, Y., Zhang, H., Li, Y., Wang, Z., Fan, Q., Yu, S., … Xiao, Z. (2015). BDNF Val66Met polymorphism and plasma levels in Chinese Han population with obsessive-compulsive disorder and generalized anxiety disorder. Journal of Affective Disorders, 186(2015), 7–12.
   Google Scholar
• Weems, C. F., Pina, A. A., Costa, N. M., Watts, S. E., Taylor, L. K., & Cannon, M. F. (2007). Predisaster trait anxiety and negative affect predict posttraumatic stress in youths after hurricane Katrina. Journal of Consulting and Clinical Psychology, 75(1), 154–159.
   PubMed Web of Science ®Google Scholar
• Weems, C. F., & Stickle, T. R. (2005). Anxiety disorders in childhood: Casting a nomological net. Clinical Child and Family Psychology Review, 8(2), 107–134.
   PubMed Web of Science ®Google Scholar
• Willis-Owen, S. A. G., Fullerton, J., Surtees, P. G., Wainwright, N. W. J., Miller, S., & Flint, J. (2005). The Val66Met coding variant of the brain-derived neurotrophic factor (BDNF) gene does not contribute toward variation in the personality trait neuroticism. Biological Psychiatry, 58(9), 738–742.
   Web of Science ®Google Scholar
• Wright, G. E., Niehaus, D. J., Koen, L., Drögemöller, B. I., & Warnich, L. (2011). Psychiatric genetics in South Africa: Cutting a rough diamond. African Journal of Psychiatry, 14(5), 355–366.
   Google Scholar
• Yamada, K., Mizuno, M., & Nabeshima, T. (2002). Role for brain-derived neurotrophic factor in learning and memory. Life Sciences, 70(7), 735–744.
   PubMed Web of Science ®Google Scholar
• Zavos, H. M. S., Gregory, A. M., & Eley, T. C. (2012). Longitudinal genetic analysis of anxiety sensitivity. Developmental Psychology, 48(1), 204–212.
   PubMed Web of Science ®Google Scholar
• Zavos, H. M. S., Rijsdijk, F. V., & Eley, T. C. (2012). A longitudinal, genetically informative, study of associations between anxiety sensitivity, anxiety and depression. Behavior Genetics, 42(4), 592–602.
   Web of Science ®Google Scholar
• Zavos, H. M. S., Rijsdijk, F. V., Gregory, A. M., & Eley, T. C. (2010). Genetic influences on the cognitive biases associated with anxiety and depression symptoms in adolescents. Journal of Affective Disorders, 124(1–2), 45–53.
   Web of Science ®Google Scholar
• Zavos, H. M. S., Wong, C. C. Y., Barclay, N. L., Keers, R., Mill, J., Rijsdijk, F. V., … Eley, T. C. (2012). Anxiety sensitivity in adolescence and young adulthood: The role of stressful life events, 5HTTLPR and their interaction. Depression and Anxiety, 29(5), 400–408.
   PubMed Web of Science ®Google Scholar
• Zeni, C. P., Tramontina, S., Zeni, T. A., Coelho, R., Pheula, G., Bernardi, J., … Rohde, L. A. (2013). The Val66Met polymorphism at the BDNF gene does not influence Wisconsin Card Sorting test results in children and adolescents with bipolar disorder. Revista Brasileira De Psiquiatria, 35(1), 44–50.
   PubMed Web of Science ®Google Scholar