References

• Binder, E. B. (2017). Dissecting the molecular mechanisms of gene x environment interactions: Implications for diagnosis and treatment of stress-related psychiatric disorders. European Journal of Psychotraumatology, 8, 1412745.
   PubMed Web of Science ®Google Scholar
• Cirulli, E. T., & Goldstein, D. B. (2010). Uncovering the roles of rare variants in common disease through whole-genome sequencing. Nature Reviews Genetics, 11(6), 415–9.
   PubMed Web of Science ®Google Scholar
• Cirulli, E. T., Singh, A., Shianna, K. V., Ge, D., Smith, J. P., Maia, J. M., … Goldstein, D. B. (2010). Screening the human exome: A comparison of whole genome and whole transcriptome sequencing. Genome Biology, 11(5), R57.
   Web of Science ®Google Scholar
• Duncan, L. E., Cooper, B. N., & Shen, H. (2018). Robust findings from 25 years of PTSD genetics research. Current Psychiatry Reports, 20(12), 115.
   Web of Science ®Google Scholar
• Duncan, L. E., Ratanatharathorn, A., Aiello, A. E., Almli, L. M., Amstadter, A. B., Ashley-Koch, A. E., … Koenen, K. C. (2018). Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability. Molecular Psychiatry, 23(3), 666–673.
   PubMed Web of Science ®Google Scholar
• Furr, J. M., Comer, J. S., Edmunds, J. M., & Kendall, P. C. (2010). Disasters and youth: A meta-analytic examination of posttraumatic stress. Journal of Consulting and Clinical Psychology, 78(6), 765–780.
   PubMed Web of Science ®Google Scholar
• Grove, M. L., Yu, B., Cochran, B. J., Haritunians, T., Bis, J. C., Taylor, K. D., … Boerwinkle, E. (2013). Best practices and joint calling of the HumanExome BeadChip: The CHARGE consortium. PloS One, 8(7), e68095.
   PubMed Web of Science ®Google Scholar
• Guo, X., Liu, Z., Wang, X., & Zhang, H. (2013). Genetic association test for multiple traits at gene level. Genetic Epidemiology, 37(1), 122–129.
   Web of Science ®Google Scholar
• Jia, P., Zheng, S., Long, J., Zheng, W., & Zhao, Z. (2011). dmGWAS: Dense module searching for genome-wide association studies in protein-protein interaction networks. Bioinformatics, 27(1), 95–102.
   PubMed Web of Science ®Google Scholar
• Johnson, J. L., Jones, M. B., Ryan, S. O., & Cobb, B. A. (2013). The regulatory power of glycans and their binding partners in immunity. Trends in Immunology, 34(6), 290–298.
   PubMed Web of Science ®Google Scholar
• Kermani, B. (2008). Artificial intelligence and global normalization methods for genotyping. United States, Patent no. US7035740B2. Retrieved from Artificial intelligence and global normalization methods for genotyping.
   Google Scholar
• Kilpatrick, D. G., Ruggiero, K. J., Acierno, R., Saunders, B. E., Resnick, H. S., & Best, C. L. (2003). Violence and risk of PTSD, major depression, substance abuse/dependence, and comorbidity: Results from the National Survey of Adolescents. Journal of Consulting and Clinical Psychology, 71(4), 692–700.
   PubMed Web of Science ®Google Scholar
• Lanius, R. A., & Olff, M. (2017). The neurobiology of PTSD. European Journal of Psychotraumatology, 8(1), 1314165.
   PubMed Web of Science ®Google Scholar
• Lescai, F., Als, T. D., Li, Q., Nyegaard, M., Andorsdottir, G., Biskopsto, M., … Borglum, A. D. (2017). Whole-exome sequencing of individuals from an isolated population implicates rare risk variants in bipolar disorder. Translational Psychiatry, 7(2), e1034.
   Web of Science ®Google Scholar
• Lind, M. J., Marraccini, M. E., Sheerin, C. M., Bountress, K., Bacanu, S. A., Amstadter, A. B., & Nugent, N. R. (2017). Association of posttraumatic stress disorder with rs2267735 in the ADCYAP1R1 gene: A meta-analysis. Journal of Traumatic Stress, 30(4), 389–398.
   Web of Science ®Google Scholar
• Liu, H., Nakazawa, T., Tezuka, T., & Yamamoto, T. (2006). Physical and functional interaction of Fyn tyrosine kinase with a brain-enriched Rho GTPase-activating protein TCGAP. The Journal of Biological Chemistry, 281(33), 23611–23619.
   Web of Science ®Google Scholar
• Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J., … Visscher, P. M. (2009). Finding the missing heritability of complex diseases. Nature, 461(7265), 747–753.
   PubMed Web of Science ®Google Scholar
• Matsuba, R., Imamura, M., Tanaka, Y., Iwata, M., Hirose, H., Kaku, K., … Maeda, S. (2016). Replication study in a Japanese population of six susceptibility loci for type 2 diabetes originally identified by a transethnic meta-analysis of genome-wide association studies. PloS One, 11(4), e0154093.
   Web of Science ®Google Scholar
• McCarthy, N. S., Melton, P. E., Ward, S. V., Allan, S. M., Dragovic, M., Clark, M. L., … Jablensky, A. (2016). Exome array analysis suggests an increased variant burden in families with schizophrenia. Schizophrenia Research. doi:10.1016/j.schres.2016.12.007
   Web of Science ®Google Scholar
• McLaren, W., Pritchard, B., Rios, D., Chen, Y., Flicek, P., & Cunningham, F. (2010). Deriving the consequences of genomic variants with the Ensembl API and SNP effect predictor. Bioinformatics, 26(16), 2069–2070.
   PubMed Web of Science ®Google Scholar
• Mehta, D., Bruenig, D., Carrillo-Roa, T., Lawford, B., Harvey, W., Morris, C. P., … Voisey, J. (2017). Genomewide DNA methylation analysis in combat veterans reveals a novel locus for PTSD. Acta Psychiatrica Scandinavica, 136(5), 493–505.
   Web of Science ®Google Scholar
• Nievergelt, C. M., Maihofer, A. X., Mustapic, M., Yurgil, K. A., Schork, N. J., Miller, M. W., … Baker, D. G. (2015). Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene. Psychoneuroendocrinology, 51, 459–471.
   PubMed Web of Science ®Google Scholar
• Norris, F. H., Friedman, M. J., Watson, P. J., Byrne, C. M., Diaz, E., & Kaniasty, K. (2002). 60,000 disaster victims speak: Part I. An empirical review of the empirical literature, 1981-2001. Psychiatry, 65(3), 207–239.
   PubMed Web of Science ®Google Scholar
• North, C. S., & Pfefferbaum, B. (2013). Mental health response to community disasters: A systematic review. JAMA, 310, 507–518.
   PubMed Web of Science ®Google Scholar
• Page, C. M., Baranzini, S. E., Mevik, B. H., Bos, S. D., Harbo, H. F., & Andreassen, B. K. (2015). Assessing the power of exome chips. PloS One, 10(10), e0139642.
   Web of Science ®Google Scholar
• Perreault, L. P., Legault, M. A., Barhdadi, A., Provost, S., Normand, V., Tardif, J. C., & Dube, M. P. (2014). Comparison of genotype clustering tools with rare variants. BMC Bioinformatics, 15, 52.
   Web of Science ®Google Scholar
• Price, A. L., Kryukov, G. V., de Bakker, P. I., Purcell, S. M., Staples, J., Wei, L. J., & Sunyaev, S. R. (2010). Pooled association tests for rare variants in exon-resequencing studies. The American Journal of Human Genetics, 86(6), 832–838.
   Web of Science ®Google Scholar
• Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A., Bender, D., … Sham, P. C. (2007). PLINK: A tool set for whole-genome association and population-based linkage analyses. The American Journal of Human Genetics, 81(3), 559–575.
   PubMed Web of Science ®Google Scholar
• Richards, A. L., Leonenko, G., Walters, J. T., Kavanagh, D. H., Rees, E. G., Evans, A., … O’Donovan, M. C. (2016). Exome arrays capture polygenic rare variant contributions to schizophrenia. Human Molecular Genetics, 25(5), 1001–1007.
   Web of Science ®Google Scholar
• Ruggiero, K. J., Davidson, T. M., McCauley, J., Gros, K. S., Welsh, K., Price, M., … Amstadter, A. B. (2015). Bounce Back Now! Protocol of a population-based randomized controlled trial to examine the efficacy of a Web-based intervention with disaster-affected families. Contemporary Clinical Trials, 40, 138–149.
   PubMed Web of Science ®Google Scholar
• Sack, W. H., Clarke, G. N., & Seeley, J. (1995). Posttraumatic stress disorder across two generations of Cambodian refugees. Journal of the American Academy of Child & Adolescent Psychiatry, 34(9), 1160–1166.
   PubMed Web of Science ®Google Scholar
• Sheerin, C. M., Lind, M. J., Bountress, K., Nugent, N. R., & Amstadter, A. B. (2017). The genetics and epigenetics of PTSD: Overview, recent advances, and future directions. Current Opinion in Psychology, 14, 5–11.
   Web of Science ®Google Scholar
• Stein, M. B., Jang, K. L., Taylor, S., Vernon, P. A., & Livesley, W. J. (2002). Genetic and environmental influences on trauma exposure and posttraumatic stress disorder symptoms: A twin study. American Journal of Psychiatry, 159(10), 1675–1681.
   PubMed Web of Science ®Google Scholar
• Thorens, B. (2015). GLUT2, glucose sensing and glucose homeostasis. Diabetologia, 58(2), 221–232.
   PubMed Web of Science ®Google Scholar
• Uetake, R., Sakurai, T., Kamiyoshi, A., Ichikawa-Shindo, Y., Kawate, H., Iesato, Y., … Shindo, T. (2014). Adrenomedullin-RAMP2 system suppresses ER stress-induced tubule cell death and is involved in kidney protection. PloS One, 9(2), e87667.
   Web of Science ®Google Scholar
• Visscher, P. M., Brown, M. A., McCarthy, M. I., & Yang, J. (2012). Five years of GWAS discovery. The American Journal of Human Genetics, 90(1), 7–24.
   PubMed Web of Science ®Google Scholar
• Vrieze, S. I., Feng, S., Miller, M. B., Hicks, B. M., Pankratz, N., Abecasis, G. R., … McGue, M. (2014). Rare nonsynonymous exonic variants in addiction and behavioral disinhibition. Biological Psychiatry, 75(10), 783–789.
   Web of Science ®Google Scholar
• Wang, L., Matsushita, T., Madireddy, L., Mousavi, P., & Baranzini, S. E. (2015). PINBPA: Cytoscape app for network analysis of GWAS data. Bioinformatics, 31(2), 262–264.
   Web of Science ®Google Scholar
• Wu, M. C., Lee, S., Cai, T., Li, Y., Boehnke, M., & Lin, X. (2011). Rare-variant association testing for sequencing data with the sequence kernel association test. The American Journal of Human Genetics, 89(1), 82–93.
   PubMed Web of Science ®Google Scholar