2,561
Views
31
CrossRef citations to date
0
Altmetric
Original Research Article

Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions

, , , , , , , , , & show all
Article: 1314073 | Received 22 Dec 2016, Accepted 24 Mar 2017, Published online: 21 Apr 2017

References

  • Heijnen HF, Schiel AE, Fijnheer R, et al. Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. Blood. 1999;94(11):1–13.
  • Lotvall J, Hill AF, Hochberg F, et al. Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International society for extracellular vesicles. J Extracell Vesicles. 2014;3:26913.
  • Thery C, Duban L, Segura E, et al. Indirect activation of naive CD4+ T cells by dendritic cell-derived exosomes. Nat Immunol. 2002;3(12):1156–1162.
  • Hedlund M, Nagaeva O, Kargl D, et al. Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells. Plos One. 2011;6(2):e16899.
  • King HW, Michael MZ, Gleadle JM. Hypoxic enhancement of exosome release by breast cancer cells. BMC Cancer. 2012;12:421.
  • Lin J, Li J, Huang B, et al. Exosomes: novel biomarkers for clinical diagnosis. ScientificWorldJournal. 2015;2015:657086.
  • Properzi F, Logozzi M, Exosomes: FS. the future of biomarkers in medicine. Biomark Med. 2013;7(5):769–778.
  • Kwon S-H, Liu KD, Mostov KE. Intercellular transfer of GPRC5B via exosomes drives HGF-mediated outward growth. Curr Biol. 2014;24(2):199–204.
  • Street JM, Birkhoff W, Menzies RI, et al. Exosomal transmission of functional aquaporin 2 in kidney cortical collecting duct cells. J Physiol. 2011;589(Pt 24):6119–6127.
  • Grange C, Collino F, Tapparo M, et al. Oncogenic micro-RNAs and renal cell carcinoma. Front Oncol. 2014;4:49.
  • Borges FT, Melo SA, Ozdemir BC, et al. TGF-beta1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis. J Am Soc Nephrol. 2013;24(3):385–392.
  • Chen HH, Lai PF, Lan YF, et al. Exosomal ATF3 RNA attenuates pro-inflammatory gene MCP-1 transcription in renal ischemia-reperfusion. J Cell Physiol. 2014;229(9):1202–1211.
  • Schlondorff DO. Overview of factors contributing to the pathophysiology of progressive renal disease. Kidney Int. 2008;74(7):860–866.
  • Sampangi S, Wang X, Beagley KW, et al. Human proximal tubule epithelial cells modulate autologous B-cell function. Nephrol Dial Transplant. 2015;30(10):1674–1683.
  • Wilkinson R, Wang X, Roper KE, et al. Activated human renal tubular cells inhibit autologous immune responses. Nephrol Dial Transplant. 2011;26(5):1483–1492.
  • Kassianos AJ, Wang X, Sampangi S, et al. Fractalkine-CX3CR1-dependent recruitment and retention of human CD1c+ myeloid dendritic cells by in vitro-activated proximal tubular epithelial cells. Kidney Int. 2015;87(6):1153–1163.
  • Wilkinson R, Wang X, Kassianos AJ, et al. Laser capture microdissection and multiplex-tandem PCR analysis of proximal tubular epithelial cell signaling in human kidney disease. Plos One. 2014;9(1):e87345.
  • Peng L, Yang J, Ning C, et al. Rhein inhibits integrin-linked kinase expression and regulates matrix metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio in high glucose-induced epithelial-mesenchymal transition of renal tubular cell. Biol Pharm Bull. 2012;35(10):1676–1685.
  • Glynne PA, Evans TJ. Inflammatory cytokines induce apoptotic and necrotic cell shedding from human proximal tubular epithelial cell monolayers. Kidney Int. 1999;55(6):2573–2597.
  • Kassianos AJ, Sampangi S, Wang X, et al. Human proximal tubule epithelial cells modulate autologous dendritic cell function. Nephrol Dial Transplant. 2013;28(2):303–312.
  • Lobb RJ, Becker M, Wen SW, et al. Optimized exosome isolation protocol for cell culture supernatant and human plasma. J Extracell Vesicles. 2015;4:27031.
  • Potriquet J, Laohaviroj M, Bethony J, et al. A modified FASP protocol for high-throughput preparation of protein samples for mass spectrometry. Biorxiv. 2016; Available from: http://biorxiv.org/content/early/2016/10/31/084533
  • Guo T, Kouvonen P, Koh CC, et al. Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps. Nat Med. 2015;21(4):407–413.
  • Ponce D, Brinkman DL, Potriquet J, et al. Venom proteome of the pacific sea nettle, chrysaora fuscescens (Cnidaria: scyphozoa). Toxins. 2016;8(4):102.
  • Schubert OT, Gillet LC, Collins BC, et al. Building high-quality assay libraries for targeted analysis of SWATH MS data. Nat Protoc. 2015;10(3):426–441.
  • Blattmann P, Heusel M, Aebersold R. SWATH2stats: an R/bioconductor package to process and convert quantitative SWATH-MS proteomics data for downstream analysis tools. Plos One. 2016;11(4):e0153160.
  • Choi M, Chang CY, Clough T, et al. MSstats: an R package for statistical analysis of quantitative mass spectrometry-based proteomic experiments. Bioinformatics. 2014;30(17):2524–2526.
  • Salomon C, Ryan J, Sobrevia L, et al. Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Plos One. 2013;8(7):e68451.
  • Yoo JK, Jung HY, Kim C-H, et al. miR-7641 modulates the expression of CXCL1 during endothelial differentiation derived from human embryonic stem cells. Arch Pharm Res. 2013;36(3):353–358.
  • De Filippo K, Dudeck A, Hasenberg M, et al. Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation. Blood. 2013;121(24):4930–4937.
  • Hung CC, Chang CT, Chen KH, et al. Upregulation of chemokine CXCL1/KC by leptospiral membrane lipoprotein preparation in renal tubule epithelial cells. Kidney Int. 2006;69(10):1814–1822.
  • Chiabotto G, Bruno S, Collino F, et al. Mesenchymal stromal cells epithelial transition induced by renal tubular cells-derived extracellular vesicles. Plos One. 2016;11(7):e0159163.
  • Wang B, Koh P, Winbanks C, et al. miR-200a Prevents renal fibrogenesis through repression of TGF-beta2 expression. Diabetes. 2011;60(1):280–287.
  • Wang G, Kwan BC, Lai FM, et al. Intrarenal expression of miRNAs in patients with hypertensive nephrosclerosis. Am J Hypertens. 2010;23(1):78–84.
  • Guan J, Wang G, Tam LS, et al. Urinary sediment ICAM-1 level in lupus nephritis. Lupus. 2012;21(11):1190–1195.
  • Rudnicki M, Perco P, D Haene B, et al. Renal microRNA- and RNA-profiles in progressive chronic kidney disease. Eur J Clin Invest. 2016;46(3):213–226.
  • Scian MJ, Maluf DG, David KG, et al. MicroRNA profiles in allograft tissues and paired urines associate with chronic allograft dysfunction with IF/TA. Am J Transplant. 2011;11(10):2110–2122.
  • Muller S, Nowak K. Exploring the miRNA-mRNA regulatory network in clear cell renal cell carcinomas by next-generation sequencing expression profiles. Biomed Res Int. 2014;2014:948408.
  • Maluf DG, Dumur CI, Suh JL, et al. The urine microRNA profile may help monitor post-transplant renal graft function. Kidney Int. 2014;85(2):439–449.
  • Wang N, Bu R, Duan Z, et al. Profiling and initial validation of urinary microRNAs as biomarkers in IgA nephropathy. PeerJ. 2015;3:e990.
  • Jura J, Skalniak L, Koj A. Monocyte chemotactic protein-1-induced protein-1 (MCPIP1) is a novel multifunctional modulator of inflammatory reactions. Biochim Biophys Acta. 2012;1823(10):1905–1913.
  • Gerritsma JS, Gerritsen AF, Van Kooten C, et al. Interleukin-1 alpha enhances the biosynthesis of complement C3 and factor B by human kidney proximal tubular epithelial cells in vitro. Mol Immunol. 1996;33(10):847–854.
  • Pagano MB, Zhou HF, Ennis TL, et al. Complement-dependent neutrophil recruitment is critical for the development of elastase-induced abdominal aortic aneurysm. Circulation. 2009;119(13):1805–1813.
  • Elsner J, Oppermann M, Czech W, et al. C3a activates the respiratory burst in human polymorphonuclear neutrophilic leukocytes via pertussis toxin-sensitive G-proteins. Blood. 1994;83(11):3324–3331.
  • Mongiat M, Fu J, Oldershaw R, et al. Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis. J Biol Chem. 2003;278(19):17491–17499.
  • Oskarsson T, Acharyya S, Zhang XH, et al. Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs. Nat Med. 2011;17(7):867–874.
  • Von Holst A. Tenascin C in stem cell niches: redundant, permissive or instructive? Cells Tissues Organs. 2008;188(1–2):170–177.
  • Sasaki T, Brakebusch C, Engel J, et al. Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin. EMBO J. 1998;17(6):1606–1613.
  • Ullrich A, Sures I, D’Egidio M, et al. The secreted tumor-associated antigen 90K is a potent immune stimulator. J Biol Chem. 1994;269(28):18401–18407.
  • Gonzales PA, Pisitkun T, Hoffert JD, et al. Large-scale proteomics and phosphoproteomics of urinary exosomes. J Am Soc Nephrol. 2009;20(2):363–379.