5,509
Views
54
CrossRef citations to date
0
Altmetric
Short Communication

Raman spectroscopy as a quick tool to assess purity of extracellular vesicle preparations and predict their functionality

ORCID Icon, , ORCID Icon, ORCID Icon, ORCID Icon, & ORCID Icon show all
Article: 1568780 | Received 10 Aug 2018, Accepted 09 Jan 2019, Published online: 27 Jan 2019

References

  • Herrera Sanchez MB, Bruno S, Grange C, et al. Human liver stem cells and derived extracellular vesicles improve recovery in a murine model of acute kidney injury. Stem Cell Res Ther. 2014;5(6):124.
  • Bruno S, Grange C, Collino F, et al. Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury. Plos One. 2012;7:3.
  • Adamiak M, Sahoo S. Exosomes in myocardial repair: advances and challenges in the development of next-generation therapeutics. Mol ther. 2018. DOI:10.1016/j.ymthe.2018.04.024
  • Lai RC, Arslan F, Lee MM, et al. Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury. Stem Cell Res. 2010;4(3):214–12.
  • De Bari C, Roelofs AJ. Stem cell-based therapeutic strategies for cartilage defects and osteoarthritis. Curr Opin Pharmacol. 2018;40:74–80.
  • Vonk LA, van Dooremalen SFJ, Liv N, et al. Mesenchymal stromal/stem cell-derived extracellular vesicles promote human cartilage regeneration in vitro. Theranostics. 2018;8(4):906–920.
  • Drommelschmidt K, Serdar M, Bendix I, et al. Mesenchymal stem cell-derived extracellular vesicles ameliorate inflammation-induced preterm brain injury. Brain Behav Immun. 2017;60:220–232.
  • Herrera MB, Fonsato V, Gatti S, et al. Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats. J Cell Mol Med. 2010;14(6B):1605–1618.
  • Tomasoni S, Longaretti L, Rota C, et al. Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells. Stem Cells Dev. 2013;22:5.
  • Gatti S, Bruno S, Deregibus MC, et al. Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury. Nephrol Dialysis Transplantation. 2011;26(5):1474–1483.
  • Rigo F, De Stefano N, Navarro-Tableros V, et al. Extracellular vesicles from human liver stem cells reduce injury in an Ex vivo normothermic hypoxic rat liver perfusion model. Transplantation. 2018;102(5):E205–E210.
  • Silva AM, Teixeira JH, Almeida MI, et al. Extracellular vesicles: immunomodulatory messengers in the context of tissue repair/regeneration. Eur J Pharm Sci. 2017;98:86–95.
  • Nooshabadi VT, Mardpour S, Yousefi-Ahmadipour A, et al. The extracellular vesicles-derived from mesenchymal stromal cells: A new therapeutic option in regenerative medicine. J Cell Biochem. 2018. DOI:10.1002/jcb.26726.
  • Tkach M, Kowal J, Thery C. Why the need and how to approach the functional diversity of extracellular vesicles. Philos Trans R Soc London, Ser B. 2018;372:1737.
  • Vizoso FJ, Eiro N, Cid S, et al. Mesenchymal stem cell secretome: toward cell-free therapeutic strategies in regenerative medicine. Int J Mol Sci. 2017;18:9.
  • Muraca M, Piccoli M, Franzin C, et al. Diverging concepts and novel perspectives in regenerative medicine. Int J Mol Sci. 2017;18(5):17.
  • Gardiner C, Di Vizio D, Sahoo S, et al. Techniques used for the isolation and characterization of extracellular vesicles: results of a worldwide survey. J Extracell Vesicles. 2016;5. DOI:10.3402/jev.v5.32945.
  • Webber J, Clayton A. How pure are your vesicles? J Extracell Vesicles. 2013;(2). Epub 2013/ 09/07. DOI:10.3402/jev.v2i0.19861
  • Mol EA, Goumans MJ, Doevendans PA, et al. Higher functionality of extracellular vesicles isolated using size-exclusion chromatography compared to ultracentrifugation. Nanomed Nanotechnol Biol Med. 2017;13(6):2061–2065.
  • Lotvall J, Hill AF, Hochberg F, et al. Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the international society for extracellular vesicles. J Extracell Vesicles. 2014;3:26913.
  • Lener T, Gimona M, Aigner L, et al. Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper. J Extracell Vesicles. 2015;4. DOI:10.3402/jev.v4.30087.
  • Tatischeff I, Larquet E, Falcon-Perez JM, et al. Fast characterisation of cell-derived extracellular vesicles by nanoparticles tracking analysis, cryo-electron microscopy, and Raman tweezers microspectroscopy. J Extracell Vesicles. 2012;1. DOI:10.3402/jev.v1i0.19179
  • Smith ZJ, Lee C, Rojalin T, et al. Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane content. J Extracell Vesicles. 2015;4. DOI:10.3402/jev.v4.28533.
  • Krafft C, Wilhelm K, Eremin A, et al. A specific spectral signature of serum and plasma-derived extracellular vesicles for cancer screening. Nanomedicine. 2016. Epub 2016/ 12/15. DOI:10.1016/j.nano.2016.11.016.
  • Tirinato L, Gentile F, Di Mascolo D, et al. SERS analysis on exosomes using super-hydrophobic surfaces. Microelectron Eng. 2012;97:337–340.
  • Lee C, Carney RP, Hazari S, et al. 3D plasmonic nanobowl platform for the study of exosomes in solution. Nanoscale. 2015;7(20):9290–9297.
  • Lee C, Carney R, Lam K, et al. SERS analysis of selectively captured exosomes using an integrin-specific peptide ligand. J Raman Spectroscopy. 2017;48(12):1771–1776.
  • Gualerzi A, Niada S, Giannasi C, et al. Raman spectroscopy uncovers biochemical tissue-related features of extracellular vesicles from mesenchymal stromal cells. Sci Rep. 2017;7. DOI:10.1038/s41598-017-10448-1.
  • Nordin JZ, Lee Y, Vader P, et al. Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties. Nanomed Nanotechnol Biol Med. 2015;11(4):879–883.
  • Van Deun J, Mestdagh P, Agostinis P, et al. EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research. Nat Methods. 2017;14(3):228–232.
  • Bruno S, Grange C, Tapparo M, et al. Human liver stem cells suppress T-Cell Proliferation, NK activity, and dendritic cell differentiation. Stem Cells Int. 2016. DOI:10.1155/2016/8468549.
  • Maiolo D, Paolini L, Di Noto G, et al. Colorimetric nanoplasmonic assay to determine purity and titrate extracellular vesicles. Anal Chem. 2015;87(8):4168–4176.
  • Mihaly J, Deak R, Szigyarto IC, et al. Characterization of extracellular vesicles by IR spectroscopy: fast and simple classification based on amide and C-H stretching vibrations. Biochim Biophys Acta, Biomembr. 2017;1859(3):459–466.
  • Rygula A, Majzner K, Marzec KM, et al. Raman spectroscopy of proteins: a review. J Raman Spectroscopy. 2013;44(8):1061–1076.
  • Czamara K, Majzner K, Pacia MZ, et al. Raman spectroscopy of lipids: a review. J Raman Spectroscopy. 2015;46(1):4–20.
  • Théry C, Witwer KW, Aikawa E, et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the international society for extracellular vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2019;8(1):1535750.
  • Paolini L, Zendrini A, Di Noto G, et al. Residual matrix from different separation techniques impacts exosome biological activity. Sci Rep. 2016;6. DOI:10.1038/srep23550.
  • Lehrich BM, Liang Y, Khosravi P, et al. Fetal bovine serum-derived extracellular vesicles persist within vesicle-depleted culture media. Int J Mol Sci. 2018;19:11.
  • Wei ZY, Batagov AO, Carter DRF, et al. Fetal bovine serum RNA interferes with the cell culture derived extracellular RNA. Sci Rep. 2016;6. DOI:10.1038/srep31175
  • Niada S, Giannasi C, Gualerzi A, et al. Differential proteomic analysis predicts appropriate applications for the secretome of adipose-derived mesenchymal stem/stromal cells and dermal fibroblasts. Stem Cell Int. 2018. Article ID 7309031. DOI:10.1155/2018/7309031
  • Qin Y, Wang L, Gao Z, et al. Bone marrow stromal/stem cell-derived extracellular vesicles regulate osteoblast activity and differentiation in vitro and promote bone regeneration in vivo. Sci Rep. 2016;6. DOI:10.1038/srep21961