Plasma extracellular vesicles detected by Single Molecule array technology as a liquid biopsy for colorectal cancer

References

• Cocucci E, Meldolesi J. Ectosomes and exosomes: shedding the confusion between extracellular vesicles. Trends Cell Biol. 2015;25(6):364–12.
   PubMed Web of Science ®Google Scholar
• Raposo G, Stoorvogel W. Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol. 2013;200:373–383.
   PubMed Web of Science ®Google Scholar
• Witwer KW, Buzas EI, Bemis LT, et al. Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J Extracell Vesicles. 2013;2. DOI:10.3402/jev.v2i0.20360
   PubMedGoogle Scholar
• Caby MP, Lankar D, Vincendeau-Scherrer C, et al. Exosomal-like vesicles are present in human blood plasma. Int Immunol. 2005;17:879–887.
   PubMed Web of Science ®Google Scholar
• Mathivanan S, Simpson RJ. ExoCarta: A compendium of exosomal proteins and RNA. Proteomics. 2009;9:4997–5000.
   PubMed Web of Science ®Google Scholar
• Yoshioka Y, Konishi Y, Kosaka N, et al. Comparative marker analysis of extracellular vesicles in different human cancer types. J Extracell Vesicles. 2013;2. DOI:10.3402/jev.v2i0.20424
   Google Scholar
• Raulf N, Lucarelli P, Thavaraj S, et al. Annexin A1 regulates EGFR activity and alters EGFR-containing tumour-derived exosomes in head and neck cancers. Eur J Cancer. 2018;102:52–68.
   Web of Science ®Google Scholar
• Zhao Z, Yang Y, Zeng Y, et al. A microfluidic ExoSearch chip for multiplexed exosome detection towards blood-based ovarian cancer diagnosis. Lab Chip. 2016;16:489–496.
   PubMed Web of Science ®Google Scholar
• McNamara RP, Dittmer DP. Modern techniques for the isolation of extracellular vesicles and viruses. J Neuroimmune Pharmacol. 2019. DOI:10.1007/s11481-019-09874-x
   Web of Science ®Google Scholar
• Rissin DM, Kan CW, Campbell TG, et al. Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations. Nat Biotechnol. 2010;28:595–599.
   PubMed Web of Science ®Google Scholar
• Schubert SM, Arendt LM, Zhou W, et al. Ultra-sensitive protein detection via Single Molecule arrays towards early stage cancer monitoring. Sci Rep. 2015;5:11034.
   PubMed Web of Science ®Google Scholar
• Chang L, Rissin DM, Fournier DR, et al. Single molecule enzyme-linked immunosorbent assays: theoretical considerations. J Immunol Methods. 2012;378:102–115.
   PubMed Web of Science ®Google Scholar
• Darlix A, Hirtz C, Thezenas S, et al. The prognostic value of the Tau protein serum level in metastatic breast cancer patients and its correlation with brain metastases. BMC Cancer. 2019;19:110.
   Web of Science ®Google Scholar
• Rissin DM, Fournier DR, Piech T, et al. Simultaneous detection of single molecules and singulated ensembles of molecules enables immunoassays with broad dynamic range. Anal Chem. 2011;83:2279–2285.
   PubMed Web of Science ®Google Scholar
• Thery C, Witwer E KW, Aikawa MJ, et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the international society for extracellular vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018;7:1535750.
   PubMed Web of Science ®Google Scholar
• Kowal J, Arras G, Colombo M, et al. Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes. Proc Natl Acad Sci USA. 2016;113:E968–977.
   PubMed Web of Science ®Google Scholar
• Liang J, Piao Y, Holmes L, et al. Neutrophils promote the malignant glioma phenotype through S100A4. Clin Cancer Res off J Am Assoc Cancer Res. 2014;20:187–198.
   PubMed Web of Science ®Google Scholar
• Koritzinsky EH, Street JM, Chari RR, et al. Circadian variation in the release of small extracellular vesicles can be normalized by vesicle number or TSG101. Am J Physiol Renal Physiol. 2019;317:F1098–F1110.
   PubMed Web of Science ®Google Scholar
• Ho DH, Yi S, Seo H, et al. Increased DJ-1 in urine exosome of Korean males with Parkinson’s disease. Biomed Res Int. 2014;704678:2014.
   Google Scholar
• Zakharchenko O, Greenwood C, Alldridge L, et al. Optimized protocol for protein extraction from the breast tissue that is compatible with two-dimensional gel electrophoresis. Breast Cancer. 2011;5:37–42.
   Google Scholar
• Ratón ML, Álvarez MXR, Suárez CC, et al. OptimalCutpoints: an R package for selecting optimal cutpoints in diagnostic tests. J Stat Softw. 2014;61(8):1–36.
   Web of Science ®Google Scholar
• Grambsch PM, Therneau TM. Proportional hazards tests and diagnostics based on weighted residuals. Biometrika. 1994;81(3):515–526.
   Web of Science ®Google Scholar
• FIRTH D. Bias reduction of maximum likelihood estimates. Biometrika. 1993;80(1):27–38.
   Web of Science ®Google Scholar
• Ploner M, Heinze G. coxphf: cox regression with Firth’s penalized likelihood. 2018. R package version 1.13. https://CRAN.R-project.org/package=coxphf
   Google Scholar
• R Core Team. R: A language and environment for statistical computing. 2017
   Google Scholar
• Carter L, Metcalf R, Blackhall FH, et al. Biology and clinical relevance of circulating tumour cells. J Thorac Dis. 2012;4:453–455.
   Web of Science ®Google Scholar
• Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424.
   PubMed Web of Science ®Google Scholar
• Taylor DD, Gercel-Taylor C. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol Oncol. 2008;110:13–21.
   PubMed Web of Science ®Google Scholar
• Jakobsen KR, Paulsen BS, Baek R, et al. Exosomal proteins as potential diagnostic markers in advanced non-small cell lung carcinoma. J Extracell Vesicles. 2015;4:26659.
   PubMed Web of Science ®Google Scholar
• Silva J, Garcia V, Rodriguez M, et al. Analysis of exosome release and its prognostic value in human colorectal cancer. Genes Chromosomes Cancer. 2012;51:409–418.
   PubMed Web of Science ®Google Scholar
• Matsumoto Y, Kano M, Akutsu Y, et al. Quantification of plasma exosome is a potential prognostic marker for esophageal squamous cell carcinoma. Oncol Rep. 2016;36:2535–2543.
   PubMed Web of Science ®Google Scholar
• Savina A, Vidal M, Colombo MI. The exosome pathway in K562 cells is regulated by Rab11. J Cell Sci. 2002;115:2505–2515.
   PubMed Web of Science ®Google Scholar
• Kosaka N, Iguchi H, Ochiya T. Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis. Cancer Sci. 2010;101:2087–2092.
   PubMed Web of Science ®Google Scholar
• Karanikiotis C, Skiadas I, Karina M, et al. A novel chromatographic method for Ep-CAM mRNA detection in peripheral blood and bone marrow of patients with metastatic colorectal cancer. Anticancer Res. 2005;25:319–323.
   PubMed Web of Science ®Google Scholar
• Kuhn S, Koch M, Nubel T, et al. A complex of EpCAM, claudin-7, CD44 variant isoforms, and tetraspanins promotes colorectal cancer progression. Mol Cancer Res. 2007;5:553–567.
   PubMed Web of Science ®Google Scholar
• Chai XB, Song RF, Xu F. Expression changes in epithelial cell adhesion molecule during colorectal cancer tumorigenesis. Genet Mol Res: GMR. 2015;14:7624–7629.
   Web of Science ®Google Scholar
• Zhou FQ, Qi YM, Xu H, et al. Expression of EpCAM and Wnt/beta-catenin in human colon cancer. Genet Mol Res: GMR. 2015;14:4485–4494.
   Web of Science ®Google Scholar
• Gosens MJ, van Kempen LC, van de Velde CJ, et al. Loss of membranous Ep-CAM in budding colorectal carcinoma cells. Mod Pathol. 2007;20:221–232.
   Web of Science ®Google Scholar
• Mora EM, Alvarez-Cubela S, Oltra E. Biobanking of exosomes in the era of precision medicine: are we there yet? Int J Mol Sci. 2015;17. DOI:10.3390/ijms17010013
   Web of Science ®Google Scholar
• Wolf P. The nature and significance of platelet products in human plasma. Br J Haematol. 1967;13:269–288.
   PubMed Web of Science ®Google Scholar
• Baek R, Sondergaard EK, Varming K, et al. The impact of various preanalytical treatments on the phenotype of small extracellular vesicles in blood analyzed by protein microarray. J Immunol Methods. 2016;438:11–20.
   PubMed Web of Science ®Google Scholar
• Eitan E, Green J, Bodogai M, et al. Age-related changes in plasma extracellular vesicle characteristics and internalization by leukocytes. Sci Rep. 2017;7:1342.
   Web of Science ®Google Scholar