2,472
Views
8
CrossRef citations to date
0
Altmetric
Review Article

How to assess for the full economic value of vaccines? From past to present, drawing lessons for the future

Article: 1719588 | Received 27 Jun 2019, Accepted 15 Jan 2020, Published online: 31 Jan 2020

References

  • Drummond M, Sculpher MJ, Claxton K, et al. Methods for the economics evaluation of health care programmes. 4th ed. Oxford University Press, Oxford, MS,USA; 2015.
  • Neumann P, Sanders G, Russel L, et al. Cost-effectiveness in health and medicine. 2nd ed. Oxford University Press, Oxford, MS,USA; 2017.
  • Eckermann S, Pekarsky B. Can the real opportunity cost stand up: displaced services, the straw man outside the room. Pharmacoeconomics. 2014;32(4):319–15.
  • Bonanni P, Picazo JJ, Remy V. The intangible benefits of vaccination - what is the true economic value of vaccination? J Mark Access Health Policy. 2015;3: 26964
  • Szucs T, Quilici S, Panfilo M. From population to public institutions: what needs to be changed to benefit from the full value of vaccination. J Mark Access Health Policy. 2015;3: 26965
  • Standaert B, Rappuoli R. 3. How comprehensive can we be in the economic assessment of vaccines? J Mark Access Health Policy. 2017;5(1):1336044.
  • Gessner BD, Kaslow D, Louis J, et al. Estimating the full public health value of vaccination. Vaccine. 2017;35(46):6255–6263.
  • Lam E, Schluter WW, Masresha BG, et al. Development of a district-level programmatic assessment tool for risk of measles virus transmission. Risk Anal. 2017;37(6):1052–1062.
  • Standaert B, Rappuoli R. Towards a more comprehensive approach for a total economic assessment of vaccines?: 1. The building blocks for a health economic assessment of vaccination. J Mark Access Health Policy. 2017;5(1):1335162.
  • Bruijning-Verhagen P, van Dongen JAP, Verberk JDM, et al. Updated cost-effectiveness and risk-benefit analysis of two infant rotavirus vaccination strategies in a high-income, low-endemic setting. BMC Med. 2018;16(1):168.
  • Cutting WA. Cost-benefit evaluations of vaccination programmes. Lancet. 1980;2(8195 pt 1):634–635.
  • Mauskopf J, Standaert B, Connolly MP, et al. Economic analysis of vaccination programs. Value Health. 2018;21(10):1133–1149.
  • Standaert B. Are changes occurring in the perceived value of vaccines? Belg Paeds. 2016;18:321–323.
  • Bloom DE, Canning D, Jamison DT. Health, wealth, and welfare. Finance Dev. 2004;41:10–15.
  • Jit M, Hutubessy R, Png ME, et al. The broader economic impact of vaccination: reviewing and appraising the strength of evidence. BMC Med. 2015;13:209.
  • van der Putten IM, Evers SM, Deogaonkar R, et al. Stakeholders’ perception on including broader economic impact of vaccines in economic evaluations in low and middle income countries: a mixed methods study. BMC Public Health. 2015;15:356.
  • Saadatian-Elahi M, Horstick O, Breiman RF, et al. Beyond efficacy: the full public health impact of vaccines. Vaccine. 2016;34(9):1139–1147.
  • Standaert B, Rappuoli R. 2. How is the economic assessment of vaccines performed today? J Mark Access Health Policy. 2017;5(1):1335163.
  • Sanders JL. Quantitative guidelines for communicable disease control programs. Biometrics. 1971;27(4):883–893.
  • Sethi SP. Quantitative guidelines for communicable disease control program: a complete synthesis. Biometrics. 1974;30(4):681–691.
  • Grab B, Cvjetanovic B. Simple method for rough determination of the cost-benefit balance point of immunization programmes. Bull World Health Organ. 1971;45(4):536–541.
  • Zerbe RD. Benefit-cost analysis. New York, NY: HarperCollins College Publishers; 1994. p. 551.
  • Blume S. The erosion of public sector vaccine production: the case of the Netherlands. In: Holmberg C, Blume S, Greenough P, editors. The politics of vaccination. Manchester University Press, Manchester, UK; 2017. p. 148–173.
  • Barnum HN, Tarantola D, Setiady IF. Cost-effectiveness of an immunization programme in Indonisia. Bull World Health Organ. 1980;58(3):499–503.
  • Willems JS, Sanders CR, Riddiough MA, et al. Cost effectiveness of vaccination against pneumococcal pneumonia. N Engl J Med. 1980;303(10):553–559.
  • Jonsson B, Horisberger B, Bruguera M, et al. Cost-benefit analysis of hepatitis-B vaccination: A computerized decision model for Spain. Int J Technol Assess Health Care. 1991;7(3):379–402.
  • Dienstag JL, Silverstein MD, Mulley AG. The cost-effectiveness of hepatitis B vaccine. J Infect. 1983;7(Suppl 1):81–84.
  • Vanderslott S, Dadonaite B, Roser M. Vaccination; 2018. Available from: https://ourworldindata.org/vaccination
  • Anderson RM, May R. Infectious diseases of humans. Oxford: Oxford University Press; 1991.
  • Lieu TA, Ray GT, Black SB, et al. Projected cost-effectiveness of pneumococcal conjugate vaccination of healthy infants and young children. JAMA. 2000;283(11):1460–1468.
  • Melegaro A, Edmunds WJ. Cost-effectiveness analysis of pneumococcal conjugate vaccination in England and Wales. Vaccine. 2004;22(31–32):4203–4214.
  • Brisson M, Edmunds WJ. The cost-effectiveness of varicella vaccination in Canada. Vaccine. 2002;20(7–8):1113–1125.
  • Insinga RP, Dasbach EJ, Elbasha EH. Epidemiologic natural history and clinical management of Human Papillomavirus (HPV) Disease: a critical and systematic review of the literature in the development of an HPV dynamic transmission model. BMC Infect Dis. 2009;9:119.
  • Brisson M, Melkonyan G, Drolet M, et al. Modeling the impact of one- and two-dose varicella vaccination on the epidemiology of varicella and zoster. Vaccine. 2010;28(19):3385–3397.
  • Atkins KE, Shim E, Pitzer VE, et al. Impact of rotavirus vaccination on epidemiological dynamics in England and Wales. Vaccine. 2012;30(3):552–564.
  • Edmunds WJ, Brisson M, Melegaro A, et al. The potential cost-effectiveness of acellular pertussis booster vaccination in England and Wales. Vaccine. 2002;20(9–10):1316–1330.
  • Barnighausen T, Berkley S, Bhutta ZA, et al. Reassessing the value of vaccines. Lancet Glob Health. 2014;2(5):e251–2.
  • Deogaonkar R, Hutubessy R, van der Putten I, et al. Systematic review of studies evaluating the broader economic impact of vaccination in low and middle income countries. BMC Public Health. 2012;12:878.
  • Jit M, Hutubessy R. Methodological challenges to economic evaluations of vaccines: is a common approach still possible? Appl Health Econ Health Policy. 2016;14(3):245–252.
  • Demarteau N, Breuer T, Standaert B. Selecting a mix of prevention strategies against cervical cancer for maximum efficiency with an optimization program. Pharmacoeconomics. 2012;30(4):337–353.
  • Standaert BA, Curran D, Postma MJ. Budget constraint and vaccine dosing: a mathematical modelling exercise. Cost Eff Resour Alloc. 2014;12(1):3.
  • Sauboin C, Van Vlaenderen I, Van Bellinghen LA, et al. Reducing malaria mortality at the lowest budget: an optimization tool for selecting malaria preventative interventions applied to Ghana. MDM Policy Pract. 2019;4(2):2381468319861346.
  • Standaert B, Van Vlaenderen I, Van Bellinghen L-A, et al. Constrained optimization for the selection of influenza vaccines to maximize the population benefit: a demonstration project. Appl Health Econ Health Policy. 2019. doi:10.1007/s40258-019-00534-y. [Epub ahead of print]
  • Standaert B, Schecroun N, Ethgen O, et al. Optimising the introduction of multiple childhood vaccines in Japan: A model proposing the introduction sequence achieving the highest health gains. Health Policy. 2017;121(12):1303–1312.
  • Connolly MP, Topachevskyi O, Standaert B, et al. The impact of rotavirus vaccination on discounted net tax revenue in Egypt: a government perspective analysis. Pharmacoeconomics. 2012;30(8):681–695.
  • Kotsopoulos N, Haitsma G, Connolly MP, et al. Estimating the money flow in the economy attributed to rotavirus disease and vaccination in the Netherlands using a Social Accounting Matrix (SAM) framework. Expert Rev Pharmacoecon Outcomes Res. 2019. doi: 10.1080/14737167.2020.1693269. [Epub ahead of print]
  • Passarella R. Handbook on social accounting matrices and labour accounts. 2003; Available from: http://forum.europa.eu.int/Members/inc/dsis/employ/home
  • Garber AM, Phelps CE. Economic foundations of cost-effectiveness analysis. J Health Econ. 1997;16(1):1–31.
  • Beutels P, Scuffham PA, MacIntyre CR. Funding of drugs: do vaccines warrant a different approach? Lancet Infect Dis. 2008;8(11):727–733.
  • Standaert B, Alwan A, Strens D, et al. Improvement in hospital Quality of Care (QoC) after the introduction of rotavirus vaccination: an evaluation study in Belgium. Hum Vaccin Immunother. 2015;11(9):2266–2273.
  • Ganiats TG. Prevention, policy, and paradox: what is the value of future health? Am J Prev Med. 1997;13(1):12–17.
  • Brouwer WB, Niessen LW, Postma MJ, et al. Need for differential discounting of costs and health effects in cost effectiveness analyses. BMJ. 2005;331(7514):446–448.
  • Standaert B, Ethgen O, Emerson R, et al. Comparing cost-effectiveness results for a vaccine across different countries worldwide: what can we learn? Adv Ther. 2014;31(10):1095–1108.
  • Newall AT, Jit M, Hutubessy R. Are current cost-effectiveness thresholds for low- and middle-income countries useful? Examples from the world of vaccines. Pharmacoeconomics. 2014;32(6):525–531.
  • Robinson LA, Hammitt JK, Chang AY, et al. Understanding and improving the one and three times GDP per capita cost-effectiveness thresholds. Health Policy Plan. 2017;32(1):141–145.
  • Ferko N, Postma M, Gallivan S, et al. Evolution of the health economics of cervical cancer vaccination. Vaccine. 2008;26(Suppl 5):F3–15.
  • Hanquet G, Valenciano M, Simondon F, et al. Vaccine effects and impact of vaccination programmes in post-licensure studies. Vaccine. 2013;31(48):5634–5642.
  • Vallejo-Torres L, García-Lorenzo B, Castilla I, et al. On the estimation of the cost-effectiveness threshold: why, what, how? Value Health. 2016;19(5):558–566.
  • Berkley S. Improving access to vaccines through tiered pricing. Lancet. 2014;383(9936):2265–2267.
  • Dort T, Schecroun N, Standaert B. Improving the hospital quality of care during winter periods by optimizing budget allocation between rotavirus vaccination and bed expansion. Appl Health Econ Health Policy. 2018;16(1):123–132.
  • Halloran ME, Struchiner CJ, Longini IM Jr. Study designs for evaluating different efficacy and effectiveness aspects of vaccines. Am J Epidemiol. 1997;146(10):789–803.
  • Gessner BD, Feikin DR. Vaccine preventable disease incidence as a complement to vaccine efficacy for setting vaccine policy. Vaccine. 2014;32(26):3133–3138.
  • Wilder-Smith A, Longini I, Zuber PL, et al. The public health value of vaccines beyond efficacy: methods, measures and outcomes. BMC Med. 2017;15(1):138.
  • Cleemput I, Neyt M, Thiry N, et al. Using threshold values for cost per quality-adjusted life-year gained in health care decisions. Int J Technol Assess Health Care. 2011;27(1):5.
  • Garrison LP Jr., Kamal-Bahl S, Towse A. Toward a broader concept of value: identifying and defining elements for an expanded cost-effectiveness analysis. Value Health. 2017;20(2):213–216.
  • Marchionatti RMF. Considerations on the fundamental principles of pure political economy. New York, NY: Rotledge; 2007.
  • Largeron N, Lévy P, Wasem J, et al. Role of vaccination in the sustainability of healthcare systems. J Mark Access Health Policy. 2015;3:27043.
  • Nelson AL, Cohen JT, Greenberg D, et al. Much cheaper, almost as good: decrementally cost-effective medical innovation. Ann Intern Med. 2009;151(9):662–667.
  • Verguet S, Kim JJ, Jamison DT. Extended cost-effectiveness analysis for health policy assessment: a tutorial. Pharmacoeconomics. 2016;34(9):913–923.
  • Asaria M, Griffin S, Cookson R. Distributional cost-effectiveness analysis: a tutorial. Med Decis Making. 2016;36(1):8–19.
  • Marsh K, IJzerman M, Thokala P, et al. Multiple criteria decision analysis for health care decision making–emerging good practices: report 2 of the ISPOR MCDA emerging good practices task force. Value Health. 2016;19(2):125–137.
  • Thokala P, Devlin N, Marsh K, et al. Multiple criteria decision analysis for health care decision making–an introduction: report 1 of the ISPOR MCDA emerging good practices task force. Value Health. 2016;19(1):1–13.
  • Lahdelma R, Salminen P. Stochastic Multicriteria Acceptability Analysis (SMAA). In: Ehrgott M, Figueira JR, Greco S, editors. Trends in multiple criteria decision analysis. Boston, MA: Springer US; 2010. p. 285–315.
  • Mauskopf JA, Paul JE, Grant DM, et al. The role of cost-consequence analysis in healthcare decision-making. Pharmacoeconomics. 1998;13(3):277–288.
  • Mauskopf J, Earnshaw S. Budget-impact analysis of health care interventions, a practical guide. Adis, Cham, Switzerland; 2017.
  • Prue G, Baker P, Graham D, et al. It is time for universal HPV vaccination. Lancet. 2018;392(10151):913–914.
  • Crown W, Buyukkaramikli N, Thokala P, et al. Constrained optimization methods in health services research-an introduction: report 1 of the ISPOR optimization methods emerging good practices task force. Value Health. 2017;20(3):310–319.
  • Crown W, Buyukkaramikli N, Sir MY, et al. Application of constrained optimization methods in health services research: report 2 of the ISPOR optimization methods emerging good practices task force. Value Health. 2018;21(9):1019–1028.
  • Sarker R, Newton C. Optimization Modelling, a practical approach. CRC Press, Taylor & Francis Group, Boca Raton, FL, USA; 2008.
  • Connolly MP, Kotsopoulos N, Postma MJ, et al. The fiscal consequences attributed to changes in morbidity and mortality linked to investments in health care: a government perspective analytic framework. Value Health. 2017;20(2):273–277.
  • Rodriguez GN. Social accounting matrix and analysis of productive sectors in Mexico. Contaduria y Administracion. 2018;63(1):1–28.
  • Kotsopoulos N, Connolly MP, Postma MJ, et al. Fiscal consequences of changes in morbidity and mortality attributed to rotavirus immunisation. Vaccine. 2013;31(46):5430–5434.
  • Masters R, Anwar E, Collins B, et al. Return on investment of public health interventions: a systematic review. J Epidemiol Community Health. 2017;71(8):827–834.
  • Adler MD, Fleurbaey M. The Oxford Handbook of well-being and public policy. 1st ed. Oxford University Press, Oxford, MS, USA; 2016.
  • Attema AE. Incorporating sign-dependence in health-related social welfare functions. Expert Rev Pharmacoecon Outcomes Res. 2015;15(2):223–228.
  • Doherty M, Buchy P, Standaert B, et al. Vaccine impact: benefits for human health. Vaccine. 2016;34(52):6707–6714.
  • Poulos C, Standaert B, Sloesen B, et al. Preferences for vaccines against children’s diarrheal illness among mothers in Poland and Hungary. Vaccine. 2018;36(40):6022–6029.
  • Yerushalmi E, Hunt P, Hoorens S, et al. Exploring the use of a general equilibrium method to assess the value of a malaria vaccine: an application to Ghana. Med Decis Making Policy Pract. 2019;4(2):2381468319894345.
  • Standaert B, Strens D, Alwan A, et al. Medium- to long-term impact of rotavirus vaccination on hospital care in Belgium: A 7-year follow-up of the Rotavirus Belgium Impact Study (RotaBIS). Infect Dis Ther. 2016;5(1):31–44.
  • Sauboin C, Mihajlović J, Geets R, et al. A new way to inform decision-maker and enhance vaccination programs in countries with limited budgets - the case of Serbia. Presented at ISPOR Europe; 2019 November; Copenhagen, Denmark.
  • World Health Organization. WHO guide for standardization of economic evaluations of immunization programmes; 2019 [ 2019 Oct 1 2019 Dec 9]. Available from: https://www.who.int/immunization/newsroom/news_guidance_stadard_economic_eval_imm_programmes/en/