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Original Articles

Exploring a regional pharmaceutical innovation network as a possible solution to the market failure in the innovation of essential medicines for tropical diseases in sub-Saharan Africa

References

  • African Union (2007), ‘Africa Health Strategy: 2007 - 2015’, Third Session of the African Union Conference of Ministers of Health, 9–13 April 2007, Johannesburg, South Africa, CAMH/MIN/5(III), Addis Ababa: African Union.
  • Ali, A.A.G. and Thorbecke, E. (2000), ‘The State and Path of Poverty in Sub-Saharan Africa: Some Preliminary Results’, Journal of African Economies, 9(Suppl. 1): 41–44.
  • ANDI (African Network for Drugs and Diagnostics Innovation) (2009), ‘Strategic and Business Plan for the African Network for Drugs and Diagnostics Innovation’, TDR/ ANDI/BP/09.1, Geneva: World Health Organization and the Special Programme for Research and Training in Tropical Diseases.
  • Ashiya M. and Jindal, A. (2007), ‘Medical Research and Development Treaty: a New R&D Framework’, ICFAI Journal of Systems Management, 5(1): 23–31.
  • Berger, M., Murugi, J., Buch, E., Ijsselmuiden, C., Moran, M. Guzman, J., Devlin, M. and Kubata, B. (2010), Strengthening Pharmaceutical Innovation in Africa, s.l.: Council on Health Research for Development (COHRED) and New Partnership for Africa’s Development (NEPAD).
  • Bloom, G., Lucas, H., Edun, A., Lenneiye, M. and Milimo, J. (2000), ‘Health and Poverty in Sub-Saharan Africa’, IDS Working Paper no. 103. Brighton: Institute of Development Studies.
  • Bozeman B. and Lee, S. (2005), ‘The Impact of Research Collaboration on Scientific Productivity’, Social Science Studies, 35(5): 673–702. doi: 10.1177/0306312705052359
  • Calderón, C. and Servén, L. (2008), ‘Infrastructure and Economic Development in Sub-Saharan Africa’, Policy Research Working Paper 4712, Washington, D.C.: The World Bank.
  • Commission on Health Research for Development (1990), Health Research: Essential Link to Equity in Development, Oxford: Oxford University Press.
  • Commission on Intellectual Property Rights, Innovation and Public Health (2006), ‘Public Health, Innovation and Intellectual Property Rights’, Report of the Commission on Intellectual Property Rights, Innovation and Public Health, Geneva: WHO.
  • Committee of Experts on Public Administration (2004), ‘Developing Institutions of Governance and Public Administration in Africa’, Third session, 29 March–2 April 2004, Agenda item 3, E/C.16/2004/6, New York: United Nations Economic and Social Council.
  • Correa, C. (2002), Implications of the Doha Declaration on the TRIPS Agreement and Public Health, Geneva: World Health Organization.
  • Correa, C. (2007), Trade Related Aspects of Intellectual Property Rights: a Commentary on the TRIPS Agreement, Oxford: Oxford University Press.
  • Denning, S. (2002), ‘Technical Cooperation and Knowledge Network’, in Fukuda-Parr, S., Lopes C. and Malik K. (eds), Capacity for Development: New Solutions to Old Problems, London/New York: Earthscan Publications/United Nations Development Programme, pp. 229–246.
  • Dobson, W. and Safariana, E. (2008), ‘The Transition from Imitation to Innovation: an Enquiry into China’s Evolving Institutions and Firm Capabilities’, Journal of Asian Economics, 19(4): 301–311. doi: 10.1016/j.asieco.2008.05.007
  • Drahos, P. and Braithwaite, J. (2002), Information Feudalism: Who Owns the Knowledge Economy, London: Earthscan Publications.
  • Dreher A., & Gaston, N., “Has Globalization Increased Inequality?” (2008) 16 Review of International Economics, 3, 516-536.
  • Easterly, W. and Kraay, A. (2000), ‘Small States, Small Problems? Income, Growth, and Volatility in Small States’, World Development, 28(11): 2013–2027. doi: 10.1016/S0305-750X(00)00068-1
  • Evans, G.E. (1994), ‘Intellectual Property as a Trade Issue: the Making of the Agreement on Trade-Related Aspects of Intellectual Property Rights’, World Competition, Law and Economics Review, 8(2): 137–180.
  • Evans, G.E. (2008), ‘Strategic Patent Licensing for Public Research Organizations: Deploying Restriction and Reservation Clauses to Promote Medical R&D in Developing Countries’, American Journal of Law and Medicine, 34(2–3): 175–223.
  • Falvey, R., Foster N. and Greenaway, D. (2006), ‘Intellectual Property Rights and Economic Growth’, Review of Development Economics, 10(4): 700–719. doi: 10.1111/j.1467-9361.2006.00343.x
  • Farnsworth, N.R. (1998), ‘Screening Plants for New Medicine’, in Wilson, E.O. and Peter, F.M. (eds), Biodiversity, Washington, D.C., National Academy Press, pp. 83–97.
  • Feldman, J. (2009), ‘Compulsory Licenses: the Dangers Behind the Current Practice’, Journal of International Business and Law, 1(6): 136–168.
  • Franco-Paredes, C. and Santos-Preciado, J.I. (2010), ‘The Introduction of Antimicrobial Agents in Resource-Constrained Countries: Impact on the Emergence on Resistance’, in Sosa, A. de J., Byarugaba, D.K., Amábile, C.F., Hsueh, P.-R., Kariuki, S. and Okeke, I.N. (eds), Antimicrobial Resistance in Developing Countries, Springer, pp. 59–71.
  • Frew, S., Liu, V. and Singer, P. (2009), ‘A Business Plan to Help the ‘Global South’ in its Fight Against Neglected Diseases’, Health Affairs, 28(6): 1760–1773. doi: 10.1377/hlthaff.28.6.1760
  • Hersher, R. (2012), ‘Pharma Backs Latest Attempt at a Global Health R&D Treaty’, Nature Medicine 18(6): 838. doi: 10.1038/nm0612-838a
  • IMF (International Monetary Fund) (2014), ‘IMF Conditionality’, International Monetary Fund Factsheet, Washington, D.C.: Communications Department, IMF. Available at http://www.imf.org/external/np/exr/facts/ conditio.htm [accessed 12 December 2013].
  • IGWG (Intergovernmental Working Group on Public Health, Innovation and Intellectual Property) (2007), ‘Report on developments since the first session of the Intergovernmental Working Group on Public Health, Innovation and Intellectual Property’ Second session, Provisional agenda item 2, A/PHI/IGWG/2/3, 24 October 2007, Geneva: World Health Organization.
  • Iyamu, E., Turner, E. and Asakura, T. (2002), ‘In vitro Effects of NIPRISAN, (Nix-0699): a Naturally Occurring, Potent Antisickling Agent’, British Journal of Haematology, 118(1): 337–343. doi: 10.1046/j.1365-2141.2002.03593.x
  • Kaplan W. and Laing, R. (2004), ‘Priority Medicines for Europe and the World’, WHO/EDM/PAR/2004.7, Geneva: WHO.
  • Loewenson, R. (1993), ‘Structural Adjustment and Health Policy in Africa’, International Journal of Health Services, 23(4): 717–730. doi: 10.2190/WBQL-B4JP-K1PP-J7Y3
  • Lundvall B. and Borras, S. (1997), ‘The Globalising Learning Economy: Implications for Innovation Policy’, DG XII, Commission of the European Union.
  • Oxfam International (2008), ‘Ending the R&D Crisis in Public Health’, Oxfam Briefing Paper 122, Oxford: Oxfam International.
  • Manu, T. (2012), ‘Book Review: Hiroko Yamane, Interpreting TRIPS: Globalisation of Intellectual Property Rights and Access to Medicines (Hart Publishing, 2011) 582 pp’, Queen Mary Journal of Intellectual Property, 2(1): 101–107. doi: 10.4337/qmjip.2012.01.10
  • Maskus, K. and Penubarti, M. (1995), ‘How Trade-related are Intellectual Property Rights?’, Journal of International Economics, 39(3): 227–248. doi: 10.1016/0022-1996(95)01377-8
  • Matthews, D., “Intellectual Property, Human Rights and Development: The Role of NGOs and Social Movement (Edward Elgar, 2011).
  • Mazzoleni R. and Nelson, R. (1998), ‘Economic Theories about the Benefits and Costs of Patents’, Journal of Economic Issues, 32(2): 1031–1052.
  • May, C. and Sell, S.K. (2006), Intellectual Property Rights: a Critical History, Boulder: Lynne Rienners Publishers.
  • McCoy, D., Kembhavi, G., Patel J. and Luintel, A. (2009), ‘The Bill & Melinda Gates Foundation’s Grant-Making Programme for Global Health’, The Lancet, 373(9675): 1645–1653. doi: 10.1016/S0140-6736(09)60571-7
  • Medécins Sans Frontières (2012), ‘Fighting Neglect’, Geneva: Medécins Sans Frontières. Available at http://www.msf.org. uk/sites/uk/files/Fighting_Neglect_May2012_201206081400. pdf [accessed 5 August 2014].
  • Mintzberg, H. (2006), ‘Patent Nonsense: Evidence Tells of an Industry out of Social Control’, Canadian Medical Association Journal, 175(4): 374–376. doi: 10.1503/cmaj.050575
  • Organization of African Unity (1991), Treaty Establishing the African Economic Community, 3 June 1991, 30 I.L.M. 1241 (entered into force on 12 May 1994).
  • Organization of African Unity (2000), Constitutive Act of the African Union, 11 July 2000, OAU Doc. CAB/LEG/23.15 (entered into force on 26 May 2001).
  • Oxfam International (2008), ‘Ending the R&D Crisis in Public Health’, Oxfam Briefing Paper 122, Oxford: Oxfam International.
  • Pedrique, B., Strub-Wourgaft, N., Some, C., Olliaro, P., Trouiller, P., Ford, N., Pécoul, B. and Bradol, J.-H. (2013), ‘The Drug and Vaccine Landscape for Neglected Diseases (2000–11): a Systematic Assessment’, Lancet Global Health, 1(6): 371–379. doi: 10.1016/S2214-109X(13)70078-0
  • Peters, D., Garg, A., Bloom, G., Walker, D., Brieger, W. and Rahman, H. (2008), ‘Poverty and Access to Health Care in Developing Countries’, Annals of the New York Academy of Sciences, 1136(1): 161–171. doi: 10.1196/annals.1425.011
  • Rawlins, M. (2004), ‘Cutting Costs of Drug Development?’, Nature Reviews Drug Discovery, 3(4): 360–364. doi: 10.1038/nrd1347
  • Rycroft, R. (2003), ‘Self-Organizing Innovation Networks: Implications for Globalization’, The GW Center for the Study of Globalization Occasional Paper Series CSGOP-03-07, Washington, D.C.: The GW Center for the Study of Globalization .
  • Spinello, R. (1992), ‘Ethics, Pricing and the Pharmaceutical Industry’, Journal of Business Ethics, 11(8): 617–626. doi: 10.1007/BF00872273
  • Stiglitz, J. and Jayadev, A. (2010), ‘Medicine for Tomorrow: Some Alternative Proposals to Promote Socially Beneficial Research and Development in Pharmaceuticals’, Journal of Generic Medicines, 7(3): 217–226. doi: 10.1057/jgm.2010.21
  • Subramanian A. and Wei, S. (2007), ‘The WTO Promotes Trade, Strongly but Unevenly’, International Economics 72(1): 151–175. doi: 10.1016/j.jinteco.2006.07.007
  • Taylor, D. (2003), ‘Fewer New Drugs from the Pharmaceutical Industry: a Better Understanding of the Economic Challenges Facing Research Based Companies is Needed’, British Medical Journal, 326(7386): 408–409. doi: 10.1136/bmj.326.7386.408
  • TDR/WHO (Special Programme for Research and Training in Tropical Diseases/World Health Organization) (2012), ‘Making a Difference: TDR Strategic Plan: 2012-2017’, TDR/STRA 12.2, Geneva: TDR/WHO.
  • Teng-Zeng, F.K. (2005), ‘The Same Story or New Directions? Science and Technology Within the Framework of the African Union and New Partnership for Africa’s Development’, Science and Public Policy, 32(3): 231–245. doi: 10.3152/147154305781779560
  • ’t Hoen, E. (2006), ‘Report of the Commission on Intellectual Property Rights, Innovation and Public Health: A Call to Governments’, Bulletin of the World Health Organisation, 84(5): 421–423.
  • UNESCO Institute for Statistics (2007), ‘A Global Perspective on Research and Development’, Fact Sheet no. 5, UIS/ FS/07/05, Montreal: UNESCO.
  • United Nations (2012), Population and Vital Statistics Report, United Nations Statistical Papers Series A, vol. LXIV, New York: United Nations, Department of Economic and Social Affairs.
  • United Nations General Assembly (2000), ‘United Nations Millennium Declaration’, Resolution: A/RES/55/2, Fifty-fifth session, Agenda item 60 (b), 8th plenary meeting: 18 September 2000, New York: United Nations.
  • Wade, R.H. (2004), ‘Is Globalization Reducing Poverty and Inequality?’, World Development 32(4): 567–589. doi: 10.1016/j.worlddev.2003.10.007
  • Whiteside, A. (2002), ‘Poverty and HIV/AIDS in Africa’, Third World Quarterly, 23(2): 313–332. doi: 10.1080/01436590220126667
  • WHO (1981), ‘Global Strategy for Health for All by 2000’, “Health for All” Series no. 3, Geneva: WHO.
  • WHO (1995), Tropical Disease Research: Progress 1975-1994, 12th Programme Report, Geneva: WHO.
  • WHO (1998), Control and Surveillance of African Trypanosomiasis, WHO Technical Report Series 881, Geneva: WHO.
  • WHO (2000), ‘WHO Medicines Strategy: Framework for Action in Essential Drugs and Medicines Policy 2002-2003’, Document WHO/EDM/2000.1, Geneva: WHO.
  • WHO (2001), Investing in Health for Economic Development: Report of the Commission on Macroeconomics and Health, Geneva: WHO.
  • WHO (2003a), ‘Intellectual Property Rights, Innovation and Public Health’, Fifty-sixth World Health Assembly, Provisional agenda item 14.9, Document A56/17, 12 May 2003, Geneva: WHO.
  • WHO (2003b), ‘Resolution WHA56.27: Intellectual Property Rights, Innovation and Public Health’, Fifty-sixth World Health Assembly, Tenth plenary meeting, Agenda item 14.9, Document A56/VR/10, 28 May 2003, Geneva: WHO.
  • WHO (2004), ‘The World Medicines Situation’, WHO/EDM/ PAR/2004.5, Geneva: WHO.
  • WHO (2006a), ‘[Global Framework on] Essential Health Research and Development’, Fifty-ninth World Health Assembly, Executive Board 117th session, Agenda item 4.10, EB117.R13, 27 January 2006, Geneva: WHO.
  • WHO (2006b), ‘Resolution WHA59.24: Public health, innovation, essential health research and intellectual property rights: towards a global strategy and plan of action’, Fifty-ninth World Health Assembly, Ninth plenary meeting, 27 May 2006, WHA59/2006/REC/1, Geneva: WHO, pp. 32–35.
  • WHO (2007a), ‘Neglected Diseases: a Human Rights Analysis’, TDR/SDR/SEB/ST/07.2, Geneva: WHO.
  • WHO (2007b), ‘Executive Board, Summary Records, 119th session, 6–8 November 2006, and 120th session, 22–29 January 2007’, EB119/2006-EB120/2007/REC/2, Geneva: WHO.
  • WHO (2008), ‘Global Strategy and Plan of Action on Public Health, Innovation and Intellectual Property’, Sixty-first World Health Assembly, Eighth plenary meeting, Agenda item 11.6, Resolution 61.21, A61/VR/8, 24 May 2008, Geneva: WHO.
  • WHO (2009a), ‘WHO’s Role and Responsibilities in Health Research: ‘the Bamako Global Ministerial Forum on Research for Health’, 124th Session, Provisional agenda item 4.9, EB124/12 Add.2, Geneva: WHO.
  • WHO (2009b), ‘Resolution WHA62.16: Global Strategy and Plan of Action on Public Health, Innovation and Intellectual Property’, Sixty-second World Health Assembly, Eighth plenary meeting, 22 May 2009, Geneva: WHO.
  • WHO (2009c), ‘Public Health, Innovation and Intellectual Property: Global Strategy and Plan of Action’, Executive Board, 126th session, Provisional agenda item 4.3, EB126/6, 3 December 2009, Geneva: WHO.
  • WHO (2009d), ‘Public Health, Innovation and Intellectual Property: Report of the Expert Working Group on Research and Development Financing’, Executive Board 126th session, Provisional agenda item 4.3, EB126/6 Add.1, 23 December 2009, Geneva: WHO.
  • WHO (2010a), ‘Public Health, Innovation and Intellectual Property: Global Strategy and Plan of Action’, Sixty-third World Health Assembly, Provisional agenda item 11.3, Document A63/6 Add.1, 8 April 2010, Geneva: WHO.
  • WHO (2010b), ‘Public Health, Innovation and Intellectual Property: Global Strategy and Plan of Action’, Sixty-third World Health Assembly, Provisional agenda item 11.3, Document A63/6 Add.2, 17 May 2010, Geneva: WHO.
  • WHO (2010c), ‘Research and Development Coordination and Financing: Report of the Expert Working Group’, WHO/ PHI/10/1, Geneva: WHO.
  • WHO (2013a), ‘Accelerating Work to Overcome the Global Impact of Neglected Tropical Diseases – a Roadmap for Implementation’, WHO/HTM/NTD/2012.1, Geneva: WHO.
  • WHO (2013b), Fact sheets relating to neglected tropical diseases. Available at http://www.who.int/neglected_diseases/ mediacentre/factsheet/en/ [accessed 5 August 2014].
  • WHO (2013c), ‘Neglected Tropical Diseases: Prevention, Control, Elimination and Eradication’, Sixty-sixth World Health Assembly, Provisional agenda item 16.2, Report A66/20, 15 March 2013, Geneva: WHO.
  • WHO (2014), ‘Access to Essential Medicines’, Executive Board 134th session, Provisional agenda item 9.7, EB134/31, Geneva: WHO.
  • WHO Regional Committee for Africa (2008a), ‘Adoption of the Ouagadougou Declaration on Primary Health Care and Health Systems in Africa: Achieving Better Health for Africa in the New Millennium’, Fifty-eighth session, Yaounde, Republic of Cameroon, 1–5 September 2008, AFR/RC58/R3, Brazzaville: WHO Regional Office for Africa.
  • WHO Regional Committee for Africa (2008b), ‘Adoption of the Algiers Declaration on Research for Health in the African Region’, Fifty-eighth Session, Provisional agenda item 10, AFR/RC58/12, 23–26 June 2008, Geneva: WHO.
  • WHO Regional Committee for Africa (2009), ‘Tackling Neglected Tropical Diseases in the Africa Region’, Fifty-ninth session, Kigali, Republic of Rwanda, 31 August–4 September 2009, provisional agenda item 8(8), AFR/RC59/10, Brazzaville: WHO Regional Office for Africa.
  • WTO (World Trade Organization) (1994), ‘Agreement on Trade Related Aspects of Intellectual Property Rights, 15 April 1994, Final Act Embodying the Results of the Uruguay Round of Multilateral Trade Negotiations, Legal Instruments—Results of the Uruguay Round, Annex 1C, vol. 31, 13 I.L.M. 1197, Geneva: WTO.
  • WTO (2001a), Africa Group Statement on TRIPS and Public Health: Informal Session of the TRIPS Council, 25 July 2001, IP/C/W/296, Geneva: WTO.
  • WTO (2001b), Document IP/C/W/312 (TRIPS Council), WT/ GC/W/450 (General Council), 4 October 2001, Geneva: WTO.
  • WTO (2002), ‘Ministerial Declaration on the TRIPS Agreement and Public Health’, WT/MIN(01)/DEC/2, 20 November 2001, 41 I.L.M. 755, Geneva: WTO.
  • Yu, P. (2002), ‘Toward a Nonzero-sum Approach to Resolving Global Intellectual Property Disputes: What We Can Learn from Mediators, Business Strategists, and International Relations Theorists’, University of Cincinnati Law Review, 70(2): 569–650.

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