Human and novel coronavirus infections in children: a review

References

• Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–733.
   Google Scholar
• Zhou P, Yang X-L, Wang X-G, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579:270–273.
   Google Scholar
• World Health Organization. Summary of probable SARS cases with onset of illness from 1 November 2002 to 31 July 2003. Geneva: WHO. [cited 2020 Mar 21]. Available from: https://www.who.int/csr/sars/country/table2004_04_21/en/
   Google Scholar
• Fung WK, Yu PLH. SARS case-fatality rates. CMAJ. 2003;169:277–278.
   Google Scholar
• Stockman LJ, Massoudi MS, Helfand R, et al. Severe acute respiratory syndrome in children. Pediatr Infect Dis J. 2007;26:68–74.
   Google Scholar
• Zaki AM, van Boheemen S, Bestebroer TM, et al. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med. 2012;367:1814–1820.
   Google Scholar
• World Health Organization. Middle East respiratory syndrome coronavirus (MERS-CoV) [Internet]. Geneva: WHO [cited 2020 Mar 29]. Available from: http://www.who.int/emergencies/mers-cov/en/
   Google Scholar
• Bartenfeld M, Griese S, Uyeki T, et al. Middle East respiratory syndrome coronavirus and children. Clin Pediatr (Phila). 2017;56:187–189.
   Google Scholar
• Thabet F, Chehab M, Bafaqih H, et al. Middle East respiratory syndrome coronavirus in children. Saudi Med J. 2015;36:484–486.
   Google Scholar
• Memish ZA, Al-Tawfiq JA, Assiri A, et al. Middle East respiratory syndrome coronavirus disease in children. Pediatr Infect Dis J. 2014;33:904–906.
   Google Scholar
• Alfaraj SH, Al-Tawfiq JA, Altuwaijri TA, et al. Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia. Front Med. 2019;13:126–130.
   Google Scholar
• McIntosh K, Dees JH, Becker WB, et al. Recovery in tracheal organ cultures of novel viruses from patients with respiratory disease. Proc Natl Acad Sci USA. 1967;57:933–940.
   Google Scholar
• Coronaviruses, Including SARS and MERS. Red book 2018. red book online. AAP point-of-care-solutions. [cited 2020 Mar 29]. Available from: https://redbook.solutions.aap.org/chapter.aspx?sectionid=189640073&bookid=2205
   Google Scholar
• Poon LLM, Chu DKW, Chan KH, et al. Identification of a novel coronavirus in bats. J Virol. 2005;79:2001–2009.
   Google Scholar
• Lau SKP, Woo PCY, Li KSM, et al. Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats. Proc Natl Acad Sci USA. 2005;102:14040–14045.
   Google Scholar
• Li W, Shi Z, Yu M, et al. Bats are natural reservoirs of SARS-like coronaviruses. Science. 2005;310:676–679.
   Google Scholar
• Hui DS, Memish ZA, Zumla A. Severe acute respiratory syndrome vs the Middle East respiratory syndrome. Curr Opin Pulm Med. 2014;20:233–241.
   Google Scholar
• Zhang T, Wu Q, Zhang Z. Probable pangolin origin of SARS-CoV-2 associated with the COVID-19 outbreak. Curr Biol. 2020;30:1346–1351.
   Google Scholar
• Gorbalenya AE, Baker SC, Baric RS, et al. The species severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nat Microbiol. 2020;5:536–544.
   Google Scholar
• Li W, Moore MJ, Vasilieva N, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature. 2003;426:450–454.
   Google Scholar
• Jia HP, Look DC, Shi L, et al. ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. J Virol. 2005;79:14614–14621.
   Google Scholar
• Hamming I, Timens W, Bulthuis MLC, et al. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol. 2004;203:631–637.
   Google Scholar
• Li Y, Zhou W, Yang L, et al. Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor. Pharmacol Res. 2020;157:104833.
   Google Scholar
• Wilson ME, Chen LH. Travellers give wings to novel coronavirus (2019-nCoV). J Travel Med. 2020;27:taaa15.
   Google Scholar
• Jin Y, Yang H, Ji W, et al. Virology, epidemiology, pathogenesis, and control of COVID-19. Viruses. 2020;12:372.
   Google Scholar
• Chen Y, Li L. SARS-CoV-2: virus dynamics and host response. Lancet Infect Dis. 2020;20:515–516.
   Google Scholar
• Pedersen SF, Ho Y-C. SARS-CoV-2: a storm is raging. J Clin Invest. 2020;130:2202–2205.
   Google Scholar
• Hara M, Takao S. Coronavirus infections in pediatric outpatients with febrile respiratory tract infections in Hiroshima, Japan, over a 3-year period. Jpn J Infect Dis. 2015;68:523–525.
   Google Scholar
• Gaunt ER, Hardie A, Claas ECJ, et al. Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method. J Clin Microbiol. 2010;48:2940–2947.
   Google Scholar
• Zeng Z-Q, Chen D-H, Tan W-P, et al. Epidemiology and clinical characteristics of human coronaviruses OC43, 229E, NL63, and HKU1: a study of hospitalized children with acute respiratory tract infection in Guangzhou, China. Eur J Clin Microbiol Infect Dis. 2018;37:363–369.
   Google Scholar
• Heimdal I, Moe N, Krokstad S, et al. Human coronavirus in hospitalized children with respiratory tract infections: a 9-year population-based study from Norway. J Infect Dis. 2019;219:1198–1206.
   Google Scholar
• Prill MM, Iwane MK, Edwards KM, et al. Human coronavirus in young children hospitalized for acute respiratory illness and asymptomatic controls. Pediatr Infect Dis J. 2012;31:235–240.
   Google Scholar
• Morikawa S, Hiroi S, Kase T. Detection of respiratory viruses in gargle specimens of healthy children. J Clin Virol. 2015;64:59–63.
   Google Scholar
• Chonmaitree T, Revai K, Grady JJ, et al. Viral upper respiratory tract infection and otitis media complication in young children. Clin Infect Dis. 2008;46:815–823.
   Google Scholar
• Ogimi C, Englund JA, Bradford MC, et al. Characteristics and outcomes of coronavirus infection in children: the role of viral factors and an immunocompromised state. J Pediatr Infect Dis. 2019;8:21–28.
   Google Scholar
• Varghese L, Zachariah P, Vargas C, et al. Epidemiology and clinical features of human coronaviruses in the pediatric population. J Pediatr Infect Dis. 2018;7:151–158.
   Google Scholar
• Lee J, Storch GA. Characterization of human coronavirus OC43 and human coronavirus NL63 infections among hospitalized children <5 years of age. Pediatr Infect Dis J. 2014;33:814–820.
   Google Scholar
• Arbour N, Ekandé S, Côté G, et al. Persistent infection of human oligodendrocytic and neuroglial cell lines by human coronavirus 229E. J Virol. 1999;73:3326–3337.
   Google Scholar
• Yeh EA, Collins A, Cohen ME, et al. Detection of coronavirus in the central nervous system of a child with acute disseminated encephalomyelitis. Pediatrics. 2004;113(1 Pt 1):e73–e76.
   Google Scholar
• Morfopoulou S, Brown JR, Davies EG, et al. Human coronavirus OC43 associated with fatal encephalitis. N Engl J Med. 2016;375:497–498.
   Google Scholar
• Turgay C, Emine T, Ozlem K, et al. A rare cause of acute flaccid paralysis: human coronaviruses. J Pediatr Neurosci. 2015;10:280–281.
   Google Scholar
• Leung TF, Chan PKS, Wong WKG, et al. Human coronavirus NL63 in children: epidemiology, disease spectrum, and genetic diversity. Hong Kong Med J. 2012;18(Suppl 2):27–30.
   Google Scholar
• Jevšnik M, Steyer A, Zrim T, et al. Detection of human coronaviruses in simultaneously collected stool samples and nasopharyngeal swabs from hospitalized children with acute gastroenteritis. Virol J. 2013;10:46.
   Google Scholar
• Risku M, Lappalainen S, Räsänen S, et al. Detection of human coronaviruses in children with acute gastroenteritis. J Clin Virol. 2010;48:27–30.
   Google Scholar
• Paloniemi M, Lappalainen S, Vesikari T. Commonly circulating human coronaviruses do not have a significant role in the etiology of gastrointestinal infections in hospitalized children. J Clin Virol. 2015;62:114–117.
   Google Scholar
• Esper F, Ou Z, Huang YT. Human coronaviruses are uncommon in patients with gastrointestinal illness. J Clin Virol. 2010;48:131–133.
   Google Scholar
• Shirato K, Imada Y, Kawase M, et al. Possible involvement of infection with human coronavirus 229E, but not NL63, in Kawasaki disease. J Med Virol. 2014;86:2146–2153.
   Google Scholar
• Lehmann C, Klar R, Lindner J, et al. Kawasaki disease lacks association with human coronavirus NL63 and human bocavirus. Pediatr Infect Dis J. 2009;28:553–554.
   Google Scholar
• Esper F, Shapiro ED, Weibel C, et al. Association between a novel human coronavirus and Kawasaki disease. J Infect Dis. 2005;191:499–502.
   Google Scholar
• Dominguez SR, Anderson MS, Glodé MP, et al. Blinded case-control study of the relationship between human coronavirus NL63 and Kawasaki syndrome. J Infect Dis. 2006;194:1697–1701.
   Google Scholar
• Chang L-Y, Chiang B-L, Kao C-L, et al. Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan. J Infect Dis. 2006;193:283–286.
   Google Scholar
• Leung CW, Chiu WK. Clinical picture, diagnosis, treatment and outcome of severe acute respiratory syndrome (SARS) in children. Paediatr Respir Rev. 2004;5:275–288.
   Google Scholar
• Cheng FWT, Ng PC, Chiu WK, et al. A case-control study of SARS versus community acquired pneumonia. Arch Dis Child. 2005;90:747–749.
   Google Scholar
• Centers for Disease Control and Prevention. Frequently asked questions about SARS. 2019 [cited 2020 Apr 9]. Available from: https://www.cdc.gov/sars/about/faq.html
   Google Scholar
• Leung C, Kwan Y, Ko P, et al. Severe acute respiratory syndrome among children. Pediatrics. 2004;113:e535–e543.
   Google Scholar
• Chiu W, Cheung PCH, Ng KL, et al. Severe acute respiratory syndrome in children: experience in a regional hospital in Hong Kong. Pediatr Crit Care Med J. 2003;4:279–283.
   Google Scholar
• Hon KLE, Leung CW, Cheng WTF, et al. Clinical presentations and outcome of severe acute respiratory syndrome in children. Lancet. 2003;361:1701–1703.
   Google Scholar
• Bitnun A, Allen U, Heurter H, et al. Children hospitalized with severe acute respiratory syndrome-related illness in Toronto. Pediatrics. 2003;112:e261.
   Google Scholar
• Babyn PS, Chu WCW, Tsou IYY, et al. Severe acute respiratory syndrome (SARS): chest radiographic features in children. Pediatr Radiol. 2004;34:47–58.
   Google Scholar
• Li A, Ng P. Severe acute respiratory syndrome (SARS) in neonates and children. Arch Dis Child Fetal Neonatal Ed. 2005;90:F461–F465.
   Google Scholar
• Denison MR. Severe acute respiratory syndrome coronavirus pathogenesis, disease and vaccines: an update. Pediatr Infect Dis J. 2004;23(11 Suppl):S207–S214.
   Google Scholar
• Keeler N, Lingappa J. Severe acute respiratory syndrome: public health response and clinical practice update for an emerging disease. Curr Opin Pediatr. 2004;16:61–69.
   Google Scholar
• World Health Organization. Update 49 – SARS case fatality ratio, incubation period. Geneva: WHO [cited 2020 May 25]. Available from: https://www.who.int/csr/sars/archive/2003_05_07a/en/
   Google Scholar
• World Health Organization. Weekly epidemiological record. 24 October 2003, vol. 78, 43 (pp 373–380). Geneva: WHO [cited 2020 Apr 6]. Available from: https://www.who.int/wer/2003/wer7843/en/
   Google Scholar
• Ng PC, Leung CW, Chiu WK, et al. SARS in newborns and children. Neonatology. 2004;85:293–298.
   Google Scholar
• Shek CC, Ng PC, Fung GPG, et al. Infants born to mothers with severe acute respiratory syndrome. Pediatrics. 2003;112:e254.
   Google Scholar
• Sit SC, Yau EKC, Lam YY, et al. A young infant with severe acute respiratory syndrome. Pediatrics. 2003;112:e257.
   Google Scholar
• Cheng FWT, Ng EKO, Li AM, et al. Clinical, virologic and immunologic profiles of a young infant with severe acute respiratory syndrome. Pediatr Infect Dis J. 2005;24:567–568.
   Google Scholar
• World Health Organization. Worldwide reduction in MERS cases and deaths since 2016. Geneva: WHO [cited 2020 Apr 6]. Available from: http://www.who.int/emergencies/mers-cov/worldwide-reduction-in-mers-cases-and-deaths-since-2016/en/
   Google Scholar
• Oh M, Park WB, Park S-W, et al. Middle East respiratory syndrome: what we learned from the 2015 outbreak in the Republic of Korea. Korean J Intern Med. 2018;33:233–246.
   Google Scholar
• Drosten C, Meyer B, Müller MA, et al. Transmission of MERS-coronavirus in household contacts. N Engl J Med. 2014;371:828–835.
   Google Scholar
• Centers for Disease Control and Prevention. MERS clinical features. 2019 [cited 2020 Mar 29]. Available from: https://www.cdc.gov/coronavirus/mers/clinical-features.html
   Google Scholar
• Majumder MS, Rivers C, Lofgren E, et al. Estimation of MERS-coronavirus reproductive number and case fatality rate for the spring 2014 Saudi Arabia outbreak: insights from publicly available data. PLoS Curr. 2014;6:ecurrents.outbreaks.
   Google Scholar
• Centers for Disease Control and Prevention. Coronavirus disease 2019 (COVID-19). 2020 [cited 2020 Apr 4]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/pregnancy-breastfeeding.html
   Google Scholar
• Anfinrud P, Stadnytskyi V, Bax CE, et al. Visualizing speech-generated oral fluid droplets with laser light scattering. N Engl J Med. 2020;382:2061–2063.
   Google Scholar
• Wei WE Presymptomatic transmission of SARS-CoV-2 – singapore, January 23–March 16, 2020. MMWR. 2020 [cited 2020 Apr 8]. Available from: https://www.cdc.gov/mmwr/volumes/69/wr/mm6914e1.htm
   Google Scholar
• Report of the WHO–China Joint Mission on Coronavirus Disease 2019 (COVID-19). [cited 2020 Mar 31]. Available from: https://www.who.int/publications-detail/report-of-the-who-china-joint-mission-on-coronavirus-disease-2019-(covid-19)
   Google Scholar
• World Health Organization. Technical guidance. [cited 2020 Apr 10]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance
   Google Scholar
• Tran K, Cimon K, Severn M, et al. Aerosol generating procedures and risk of transmission of acute respiratory infections to healthcare workers: a systematic review. PLoS One. 2012;7:e35797.
   Google Scholar
• World Health Organization. Infection prevention and control during health care when novel coronavirus (nCoV) infection is suspected. [cited 2020 Apr 8]. Available from: https://www.who.int/publications-detail/infection-prevention-and-control-during-health-care-when-novel-coronavirus-(ncov)-infection-is-suspected-20200125
   Google Scholar
• van Doremalen N, Bushmaker T, Morris DH, et al. Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N Engl J Med. 2020;382:1564–1567.
   Google Scholar
• Tang A, Tong Z, Wang H, et al. Detection of novel coronavirus by RT-PCR in stool specimen from asymptomatic child, China. Emerg Infect Dis J. 2020;26:1377–1339.
   Google Scholar
• Wang W, Xu Y, Gao R, et al. Detection of SARS-CoV-2 in different types of clinical specimens. JAMA. 2020;323:1843–1844.
   Google Scholar
• Chen W, Lan Y, Yuan X, et al. Detectable 2019-nCoV viral RNA in blood is a strong indicator for the further clinical severity. Emerg Microbes Infect. 2020;9:469–473.
   Google Scholar
• Wu P, Duan F, Luo C, et al. Characteristics of ocular findings of patients with coronavirus disease 2019 (COVID-19) in Hubei Province, China. JAMA Ophthalmol. 2020;138:575–578.
   Google Scholar
• Cai J, Xu J, Lin D, et al. A case series of children with 2019 novel coronavirus infection: clinical and epidemiological features. Clin Infect Dis. 2020;ciaa198. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa198/5766430 
   Google Scholar
• Xiao F, Tang M, Zheng X. Evidence for gastrointestinal infection of SARS-CoV-2. Gastroenterology. 2020;158(6):1831–1833.e3.
   Google Scholar
• Xing Y-H, Ni W, Wu Q, et al. Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019. J Microbiol Immunol Infect. 2020;53(3):S1684-1182920030081-5.
   Google Scholar
• Hindson J. COVID-19: faecal–oral transmission? Nat Rev Gastroenterol Hepatol. 2020;17:259.
   Google Scholar
• Barth RE, Regt MJAD. Persistence of viral RNA in stool samples from patients recovering from covid-19. Br Med J. 2020;369:m1724.
   Google Scholar
• Nishiura H, Linton NM, Akhmetzhanov AR. Serial interval of novel coronavirus (COVID-19) infections. Int J Infect Dis. 2020;93:284–286.
   Google Scholar
• Kimball A Asymptomatic and presymptomatic SARS-CoV-2 infections in residents of a long-term care skilled nursing facility – king County, Washington, March 2020. MMWR. 2020;69 [cited 2020 Apr 8]. Available from: https://www.cdc.gov/mmwr/volumes/69/wr/mm6913e1.htm
   Google Scholar
• Du Z, Xu X, Wu Y, et al. Serial interval of COVID-19 among publicly reported confirmed cases. Emerg Infect Dis. 2020;26:1341–1343.
   Google Scholar
• Zou L, Ruan F, Huang M, et al. SARS-CoV-2 viral load in upper respiratory specimens of infected patients. N Engl J Med. 2020;382:1177–1179.
   Google Scholar
• Day M. Covid-19: identifying and isolating asymptomatic people helped eliminate virus in Italian village. Br Med J. 2020;368:m1165.
   Google Scholar
• Day M. Covid-19: four fifths of cases are asymptomatic, China figures indicate. Br Med J. 2020;369:m1375.
   Google Scholar
• Bai Y, Yao L, Wei T, et al. Presumed asymptomatic carrier transmission of COVID-19. JAMA. 2020;323:1406–1407.
   Google Scholar
• Hu Z, Song C, Xu C, et al. Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China. Sci China Life Sci. 2020;63:706–711.
   Google Scholar
• Qian G, Yang N, Ma AHY, et al. A COVID-19 Transmission within a family cluster by presymptomatic infectors in China. Clin Infect Dis. 2020;ciaa316. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa316/5810900
   Google Scholar
• Lu Y, Li Y, Deng W, et al. Symptomatic infection is associated with prolonged duration of viral shedding in mild coronavirus disease 2019: a retrospective study of 110 children in Wuhan. Pediatr Infect Dis J. 2020. Online ahead of print. DOI:10.1097/INF.0000000000002729
   Google Scholar
• Song R, Han B, Song M, et al. Clinical and epidemiological features of COVID-19 family clusters in Beijing, China. J Infect. 2020;SO163-4453(20):30229.
   Google Scholar
• Dong Y, Mo X, Hu Y, et al. Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China. Pediatrics. 2020;e20200702. https://pediatrics.aappublications.org/content/early/2020/03/16/peds.2020-0702/tab-article-info?versioned=true 
   Google Scholar
• Yung CF, Kam K-Q, Wong MSY, et al. Environment and personal protective equipment tests for SARS-CoV-2 in the isolation room of an infant with infection. Ann Intern Med. 2020;M20–0942. https://pubmed.ncbi.nlm.nih.gov/32236490/
   Google Scholar
• Lescure F-X, Bouadma L, Nguyen D, et al. Clinical and virological data of the first cases of COVID-19 in Europe: a case series. Lancet Infect Dis. 2020;S1473-3099(20):30200–0.
   Google Scholar
• Kam K, Yung CF, Cui L, et al. A well infant with coronavirus disease 2019 with high viral load. Clin Infect Dis. 2020;ciaa201. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa201/5766416 https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa201/5766416
   Google Scholar
• Wu Y, Guo C, Tang L, et al. Prolonged presence of SARS-CoV-2 viral RNA in faecal samples. Lancet Gastroenterol Hepatol. 2020;5:434–435.
   Google Scholar
• Danis K, Epaulard O, Bénet T, et al. Cluster of coronavirus disease 2019 (Covid-19) in the French Alps, 2020. Clin Infect Dis. 2020;ciaa424. https://doi.org/10.1093/cid/ciaa424
   Google Scholar
• Beldomenico PM. Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19. Int J Infect Dis. 2020;S1201-9712(20):30332.
   Google Scholar
• Liu Y, Eggo RM, Kucharski AJ. Secondary attack rate and superspreading events for SARS-CoV-2. Lancet. 2020;395:e47.
   Google Scholar
• Hamner L High SARS-CoV-2 attack rate following exposure at a choir practice – Skagit County, Washington, March 2020. MMWR. 2020;69 [cited 2020 May 25]. Available from: https://www.cdc.gov/mmwr/volumes/69/wr/mm6919e6.htm
   Google Scholar
• Correa-Martínez CL, Kampmeier S, Kümpers P, et al. A pandemic in times of global tourism: superspreading and exportation of COVID-19 cases from a ski area in Austria. J Clin Microbiol. 2020;58:e00588–20.
   Google Scholar
• Bi Q, Wu Y, Mei S, et al. Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study. Lancet Infect Dis. 2020;S1473-3099(20):30287–5. https://doi.org/10.1093/cid/ciaa424
   Google Scholar
• Gudbjartsson DF, Helgason A, Jonsson H, et al. Spread of SARS-CoV-2 in the Icelandic population. N Engl J Med. 2020;382: 2302–2315. NEJMoa2006100.
   Google Scholar
• He D, Zhao S, Lin Q, et al. The relative transmissibility of asymptomatic COVID-19 infections among close contacts. Int J Infect Dis. 2020;94:145–147.
   Google Scholar
• Furukawa NW, Brooks JT, Sobel J. Early release – evidence supporting transmission of severe acute respiratory syndrome coronavirus 2 while presymptomatic or asymptomatic. Emerg Infect Dis J. 26. [cited 2020 May 23]. Available from: https://wwwnc.cdc.gov/eid/article/26/7/20-1595_article
   Google Scholar
• Klompas M, Morris CA, Sinclair J, et al. Universal masking in hospitals in the Covid-19 era. N Engl J Med. 2020;382:e63.
   Google Scholar
• Lauer SA, Grantz KH, Bi Q, et al. The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application. Ann Intern Med. 2020;172:577–582.
   Google Scholar
• Backer JA, Klinkenberg D, Wallinga J. Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20–28 January 2020. Euro Surveill. 2020;25:2000062.
   Google Scholar
• Linton NM, Kobayashi T, Yang Y, et al. Incubation period and other epidemiological characteristics of 2019 novel coronavirus infections with right truncation: a statistical analysis of publicly available case data. J Clin Med. 2020;9:538.
   Google Scholar
• Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506.
   Google Scholar
• Varia M, Wilson S, Sarwal S, et al. Investigation of a nosocomial outbreak of severe acute respiratory syndrome (SARS) in Toronto, Canada. Can Med Assoc J. 2003;169:285–292.
   Google Scholar
• Virlogeux V, Fang VJ, Park M, et al. Comparison of incubation period distribution of human infections with MERS-CoV in South Korea and Saudi Arabia. Sci Rep. 2016;6:35839.
   Google Scholar
• Jiang X, Rayner S, Luo M-H. Does SARS-CoV-2 has a longer incubation period than SARS and MERS? J Med Virol. 2020;92:476–478.
   Google Scholar
• Chan JF-W, Yuan S, Kok K-H, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020;395:514–523.
   Google Scholar
• Ji L-N, Chao S, Wang Y-J, et al. Clinical features of pediatric patients with COVID-19: a report of two family cluster cases. World J Pediatr. 2020 [cited 2020 Apr 8]. DOI:10.1007/s12519-020-00356-2
   Google Scholar
• Wei M, Yuan J, Liu Y, et al. Novel coronavirus infection in hospitalized infants under 1 year of age in China. JAMA. 2020;323:1313–1314.
   Google Scholar
• Wu Z, McGoogan JM, Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72,314 cases from the Chinese Center for Disease Control and Prevention. JAMA 2020;323:1239. [cited 2020 Mar 21]. Available from: https://jamanetwork.com/journals/jama/fullarticle/2762130
   Google Scholar
• Ludvigsson JF. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr. 2020;109:1088–1095.
   Google Scholar
• Centers for Disease Control and Prevention. Coronavirus disease 2019 in children — United States, February 12–April 2, 2020. MMWR. 2020;69 [cited 2020 Apr 6]. Available from: https://www.cdc.gov/mmwr/volumes/69/wr/mm6914e4.htm
   Google Scholar
• Guan W, Ni Z, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382:1861–1862.
   Google Scholar
• Lu X, Zhang L, Du H, et al. SARS-CoV-2 infection in children. N Engl J Med. 2020;382:1663–1665.
   Google Scholar
• Cruz AT, Zeichner SL. COVID-19 in children: initial characterization of the pediatric disease. Pediatrics. 2020;e20200834. https://pediatrics.aappublications.org/content/145/6/e20200834.full
   Google Scholar
• Shekerdemian LS, Mahmood NR, Wolfe KK, et al. Characteristics and outcomes of children with coronavirus disease 2019 (COVID-19) infection admitted to US and Canadian pediatric intensive care units. JAMA Pediatr. 2020 [cited 2020 May 23]. Available from: https://jamanetwork.com/journals/jamapediatrics/fullarticle/2766037
   Google Scholar
• Lazzerini M, Putoto G. COVID-19 in Italy: momentous decisions and many uncertainties. Lancet Glob Health. 2020;8:E641–E642.
   Google Scholar
• Remuzzi A, Remuzzi G. COVID-19 and Italy: what next? Lancet. 2020;395:1225–1228.
   Google Scholar
• Livingston E, Bucher K Coronavirus disease 2019 (COVID-19) in Italy. JAMA. 2020 [cited 2020 Mar 29]. Available from: https://jamanetwork.com/journals/jama/fullarticle/2763401
   Google Scholar
• Tagarro A, Epalza C, Santos M, et al. Screening and severity of coronavirus disease 2019 (COVID-19) in children in Madrid, Spain. JAMA Pediatr. 2020;e201346. https://pubmed.ncbi.nlm.nih.gov/32267485/
   Google Scholar
• COVID-19 Alberta Statistics. [cited 2020 May 25]. Available from: https://www.alberta.ca/stats/covid-19-alberta-statistics.htm
   Google Scholar
• Government of Canada. Epidemiological summary of COVID-19 cases in Canada. 2020 [cited 2020 Apr 9]. Available from: https://www.canada.ca/en/public-health/services/diseases/2019-novel-coronavirus-infection/health-professionals/epidemiological-summary-covid-19-cases.html
   Google Scholar
• Shim E, Tariq A, Choi W, et al. Transmission potential and severity of COVID-19 in South Korea. Int J Infect Dis. 2020;93:339–344.
   Google Scholar
• Mahajan UV, Larkins-Pettigrew M. Racial demographics and COVID-19 confirmed cases and deaths: a correlational analysis of 2886 US counties. J Public Health. 2020;fdaa070. https://academic.oup.com/jpubhealth/advance-article/doi/10.1093/pubmed/fdaa070/5841318
   Google Scholar
• Garg S Hospitalization rates and characteristics of patients hospitalized with laboratory-confirmed coronavirus disease 2019 – COVID-NET, 14 States, March 1–30, 2020. MMWR. 2020;69 [cited 2020 May 25]. Available from: https://www.cdc.gov/mmwr/volumes/69/wr/mm6915e3.htm
   Google Scholar
• Shah M, Sachdeva M, Dodiuk-Gad RP. COVID-19 and racial disparities. J Am Acad Dermatol. 2020;SO190-9622(20):30659–9.
   Google Scholar
• Hooper MW, Nápoles AM, Pérez-Stable EJ. COVID-19 and racial/ethnic disparities. JAMA. 2020;SO190-9622(20):30659–9.
   Google Scholar
• Liu W, Zhang Q, Chen J, et al. Detection of Covid-19 in children in early January 2020 in Wuhan, China. N Engl J Med. 2020;382:1370–1371.
   Google Scholar
• Xu Y, Li X, Zhu B, et al. Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding. Nat Med. 2020;26:502–505.
   Google Scholar
• Tian Y, Rong L, Nian W, et al. Review article: gastrointestinal features in COVID-19 and the possibility of faecal transmission. Aliment Pharmacol Ther. 2020;51:843–851.
   Google Scholar
• Han Y, Feng Z, Sun L, et al. A comparative-descriptive analysis of clinical characteristics in 2019-Coronavirus-infected children and adults. J Med Virol. 2020. Online ahead of print. DOI:10.1097/INF.0000000000002729
   Google Scholar
• Cai X, Ma Y, Li S, et al. Clinical characteristics of 5 COVID-19 cases with non-respiratory symptoms as the first manifestation in children. Front Pediatr. 2020;8 [cited 2020 May 25]. Available from: https://www.frontiersin.org/articles/10.3389/fped.2020.00258/full
   Google Scholar
• Shen K-L, Yang Y-H. Diagnosis and treatment of 2019 novel coronavirus infection in children: a pressing issue. World J Pediatr;2020. Online ahead of print. DOI:10.1007/s12519-020-00344-6
   Google Scholar
• Gane SB, Kelly C, Hopkins C. Isolated sudden onset anosmia in COVID-19 infection. A novel syndrome? Rhinology;2020. Online ahead of print. DOI:10.4193/Rhin20.114
   Google Scholar
• Vaira LA, Salzano G, Deiana G, et al. Anosmia and ageusia: common findings in COVID-19 patients. Laryngoscope. 2020. Online ahead of print. DOI:10.4193/Rhin20.114
   Google Scholar
• Eliezer M, Hautefort C, Hamel A-L, et al. Sudden and complete olfactory loss function as a possible symptom of COVID-19. JAMA Otolaryngol Neck Surg. 2020. Online ahead of print. DOI:10.1001/jamaoto.2020.0832
   Google Scholar
• Klopfenstein T, Kadiane-Oussou NJ, Toko L, et al. Features of anosmia in COVID-19. Méd Mal Infect. 2020;SO399-077X(20):30110–4.
   Google Scholar
• Lechien JR, Barillari MR, Jouffe L, Saussez, S. Anosmia is a key symptom of COVID-19 infection and should be used as a diagnostic tool. Ear Nose Throat J. 2020;145561320925191. https://doi.org/10.1177/0145561320925191
   Google Scholar
• Vonck K, Garrez I, Herdt VD, et al. Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2. Eur J Neurol. 2020. Online ahead of print. DOI:10.1111/ene.14329
   Google Scholar
• Zhao H, Shen D, Zhou H, et al. Guillain-Barré syndrome associated with SARS-CoV-2 infection: causality or coincidence? Lancet Neurol. 2020;19:383–384.
   Google Scholar
• Leonardi M, Padovani A, McArthur JC. Neurological manifestations associated with COVID-19: a review and a call for action. J Neurol. 2020. [cited 2020 May 25]. DOI:10.1007/s00415-020-09896-z
   Google Scholar
• Klok FA, Kruip MJHA, van der Meer NJM, et al. Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: an updated analysis. Thromb Res. 2020 [cited 2020 May 23]. Available from: http://www.sciencedirect.com/science/article/pii/S0049384820301572
   Google Scholar
• Middeldorp S, Coppens M, van Haaps TF, et al. Incidence of venous thromboembolism in hospitalized patients with COVID-19. J Thromb Haemost. 2020. Online ahead of print. DOI:10.1111/jth.14888
   Google Scholar
• Poissy J, Goutay J, Caplan M, et al. Pulmonary embolism in COVID-19 patients: awareness of an increased prevalence. Circulation. 2020. Online ahead of print. DOI:10.1161/CIRCULATIONAHA.120.047430
   Google Scholar
• Kashi M, Jacquin A, Dakhil B, et al. Severe arterial thrombosis associated with Covid-19 infection. Thromb Res. 2020;192:75–77.
   Google Scholar
• Connors JM, Levy JH. COVID-19 and its implications for thrombosis and anticoagulation. Blood. 2020;135:2033–2040.
   Google Scholar
• Colonna C, Monzani N, Rocchi A, et al. Chilblains-like lesions in children following suspected Covid-19 infection. Pediatr Dermatol. 2020. Online ahead of print. DOI:10.1111/pde.14210
   Google Scholar
• Casas CG, Català A, Hernández GC, et al. Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases. Br J Dermatol. [cited 2020 May 24]. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/bjd.19163
   Google Scholar
• Andina D, Noguera‐Morel L, Bascuas‐Arribas M, et al. Chilblains in children in the setting of COVID-19 pandemic. Pediatr Dermatol. 2020 [cited 2020 May 24]. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/pde.14215
   Google Scholar
• Cordoro KM, Reynolds SD, Wattier R, et al. Clustered cases of acral perniosis: clinical features, histopathology and relationship to COVID-19. Pediatr Dermatol. 2020. Online ahead of print. DOI:10.1111/pde.14227
   Google Scholar
• Landa N, Mendieta‐Eckert M, Fonda‐Pascual P, et al. Chilblain-like lesions on feet and hands during the COVID-19 pandemic. Int J Dermatol. 2020;59:739–743.
   Google Scholar
• López‐Robles J, de la Hera I, Pardo J, et al. Chilblain-like lesions: a case series of 41 patients during the COVID-19 pandemic. Clin Exp Dermatol. 2020. Online ahead of print. DOI:10.1111/ced.14275
   Google Scholar
• Garcia‐Lara G, Linares‐González L, Ródenas‐Herranz T, et al. Chilblain-like lesions in pediatrics dermatological outpatients during the COVID-19 outbreak. Dermatol Ther. 2020;e13516. https://onlinelibrary.wiley.com/doi/10.1111/jdv.16526
   Google Scholar
• Piccolo V, Neri I, Filippeschi C, et al. Chilblain-like lesions during COVID-19 epidemic: a preliminary study on 63 patients. J Eur Acad Dermatol Venereol. 2020. DOI:10.1111/jdv.16526
   Google Scholar
• García‐Gil MF, García MG, Serrano JM, et al. Acral purpuric lesions (Erythema multiforme type) associated with thrombotic vasculopathy in a child during the COVID-19 pandemic. J Eur Acad Dermatol Venereol. 2020. Online ahead of print. DOI:10.1111/jdv.16644
   Google Scholar
• Guarneri C, Rullo EV, Pavone P, et al. Silent COVID-19: what your skin can reveal. Lancet Infect Dis. 2020;S1473-3099(20):30402–3.
   Google Scholar
• Loffredo L, Pacella F, Pacella E, et al. Conjunctivitis and COVID-19: a meta-analysis. J Med Virol. 2020. Online ahead of print. DOI:10.1002/jmv.25938
   Google Scholar
• Wu P, Liang L, Chen C, et al. A child confirmed COVID-19 with only symptoms of conjunctivitis and eyelid dermatitis. Graefes Arch Clin Exp Ophthalmol. 2020. DOI:10.1007/s00417-020-04708-6
   Google Scholar
• Wang J, Wang D, Chen G-C, et al. SARS-CoV-2 infection with gastrointestinal symptoms as the first manifestation in a neonate. Chin J Contemp Pediatr. 2020;22:211–214.
   Google Scholar
• Kan MJ, Grant LMC, Muña MA, et al. Fever without a source in an infant due to severe acute respiratory syndrome coronavirus-2. J Pediatr Infect Dis. [cited 2020 May 25]. Available from: https://academic.oup.com/jpids/advance-article/doi/10.1093/jpids/piaa044/5823619
   Google Scholar
• Paret M, Lighter J, Pellett Madan R, et al. SARS-CoV-2 infection (COVID-19) in febrile infants without respiratory distress. Clin Infect Dis. 2020;ciaa452. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa452/5821305
   Google Scholar
• Ng KF, Bandi S, Bird PW, et al. COVID-19 in neonates and infants: progression and recovery. Pediatr Infect Dis J. 2020. Online publication ahead of print. DOI:10.1097/INF.0000000000002738
   Google Scholar
• Bunyavanich S, Do A, Vicencio A. Nasal gene expression of angiotensin-converting enzyme 2 in children and adults. JAMA. 2020; 323(23): 2427–2449.
   Google Scholar
• Patel AB, Verma A. Nasal ACE2 levels and COVID-19 in children. JAMA. 2020. Online publication ahead of print. DOI:10.1001/jama.2020.8946
   Google Scholar
• Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054–1062.
   Google Scholar
• Wu C, Chen X, Cai Y, et al. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA Intern Med. 2020;e200994. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2763184
   Google Scholar
• Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020;395:507–513.
   Google Scholar
• Henry BM, Lippi G, Plebani M. Laboratory abnormalities in children with novel coronavirus disease 2019. Clin Chem Lab Med. 2020;58:1135–1138. Online publication ahead of print.
   Google Scholar
• Wong HYF, Lam HYS, Fong AH-T, et al. Frequency and distribution of chest radiographic findings in COVID-19 positive patients. Radiology2019;201160. DOI:10.1148/radiol.2020201160
   Google Scholar
• Li W, Cui H, Li K, et al. Chest computed tomography in children with COVID-19 respiratory infection. Pediatr Radiol. 2020;50:796–799.
   Google Scholar
• Xia W, Shao J, Guo Y, et al. Clinical and CT features in pediatric patients with COVID-19 infection: different points from adults. Pediatr Pulmonol. 2020;55:1169–1174.
   Google Scholar
• Liu H, Liu F, Li J, et al. Clinical and CT imaging features of the COVID-19 pneumonia: focus on pregnant women and children. J Infect. 2020;80:e7–e13.
   Google Scholar
• Han X, Cao Y, Jiang N, et al. Novel coronavirus pneumonia (COVID-19) progression course in 17 discharged patients: comparison of clinical and thin-section CT features during recovery. Clin Infect Dis. 2020;ciaa271. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa271/5813539
   Google Scholar
• Ong JSM, Tosoni A, Kim Y, et al. Coronavirus disease 2019 in critically ill children: a narrative review of the literature. Pediatr Crit Care Med. 2020. DOI:10.1097/PCC.0000000000002376
   Google Scholar
• Murthy S, Gomersall CD, Fowler RA. Care for critically ill patients with COVID-19. JAMA. 2020;323:1499. Online publication ahead of print.
   Google Scholar
• Caputo ND, Strayer RJ, Levitan R. Early self-proning in awake, non-intubated patients in the emergency department: a single ED’s experience during the COVID-19 pandemic. Acad Emerg Med. 2020;27:375–378.
   Google Scholar
• Elkattawy S, Noori M. A case of improved oxygenation in SARS-CoV-2 positive patient on nasal cannula undergoing prone positioning. Respir Med Case Rep. 2020;30:101070.
   Google Scholar
• Ghelichkhani P, Esmaeili M. Prone position in management of COVID-19 patients; a commentary. Arch Acad Emerg Med. 2020;8:e48.
   Google Scholar
• ClinicalTrials.gov. Adaptive COVID-19 treatment trial. [cited 2020 Apr 10]. Available from: https://clinicaltrials.gov/ct2/results?cond=COVID
   Google Scholar
• Bhimraj A, Morgan RL, Shumaker AH, et al. Infectious diseases society of America guidelines on the treatment and management of patients with COVID-19. Clin Infect Dis. 2020;ciaa478. https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/
   Google Scholar
• World Health Organization. Off-label use of medicines for COVID-19. [cited 2020 Apr 10]. Available from: https://www.who.int/news-room/commentaries/detail/off-label-use-of-medicines-for-covid-19
   Google Scholar
• World Health Organization. Draft landscape of COVID-19 candidate vaccines. [cited 2020 May 25]. Available from: https://www.who.int/who-documents-detail/draft-landscape-of-covid-19-candidate-vaccines
   Google Scholar
• Miyasaka M. Is BCG vaccination causally related to reduced COVID-19 mortality? EMBO Mol Med. 2020;e12661. https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/
   Google Scholar
• Riccò M, Gualerzi G, Ranzieri S, et al. Stop playing with data: there is no sound evidence that Bacille Calmette–Guérin may avoid SARS-CoV-2 infection (for now). Acta Bio Medica Atenei Parm. 2020;91:207–213.
   Google Scholar
• Redelman-Sidi G. Could BCG be used to protect against COVID-19? Nat Rev Urol. 2020;17:316–317. Online publication ahead of print.
   Google Scholar
• Jones VG, Mills M, Suarez D, et al. COVID-19 and Kawasaki disease: novel virus and novel case. Hosp Pediatr. 2020;hpeds.2020-0123. https://hosppeds.aappublications.org/content/hosppeds/early/2020/04/06/hpeds.2020-0123.full.pdf
   Google Scholar
• Royal College of Paediatrics and Child Health. Guidance. Paediatric multisystem inflammatory syndrome temporally associated with COVID-19. [cited 2020 May 23]. Available from: https://www.rcpch.ac.uk/resources/guidance-paediatric-multisystem-inflammatory-syndrome-temporally-associated-covid-19
   Google Scholar
• Verdoni L, Mazza A, Gervasoni A, et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet. 2020;395:1771–1778. Online publication ahead of print.
   Google Scholar
• World Health Organization. Multisystem inflammatory syndrome in children and adolescents with COVID-19. [cited 2020 May 23]. Available from: https://www.who.int/publications-detail/multisystem-inflammatory-syndrome-in-children-and-adolescents-with-covid-19
   Google Scholar
• Centers for Disease Control and Prevention, Health Alert Network. Multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 (COVID-19). 2020 [cited 2020 May 23]. Available from: https://emergency.cdc.gov/han/2020/han00432.asp
   Google Scholar
• Riphagen S, Gomez X, Gonzalez-Martinez C, et al. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet. 2020;395:1607–1608.
   Google Scholar
• Belhadjer Z, Méot M, Bajolle F, et al. Acute heart failure in multisystem inflammatory syndrome in children (MIS-C) in the context of global SARS-CoV-2 pandemic. Circulation. 2020. DOI:CIRCULATIONAHA.120.048360
   Google Scholar
• Rasmussen SA, Smulian JC, Lednicky JA, et al. Coronavirus disease 2019 (COVID-19) and pregnancy: what obstetricians need to know. Am J Obstet Gynecol. 2020;222:415–426.
   Google Scholar
• Zeng L, Xia S, Yuan W, et al. Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China. JAMA Pediatr. 2020;e200878. https://jamanetwork.com/journals/jamapediatrics/fullarticle/2763787
   Google Scholar
• Chen H, Guo J, Wang C, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;395:809–815.
   Google Scholar
• Zhu H, Wang L, Fang C, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020;9:51–60.
   Google Scholar
• Yu N, Li W, Kang Q, et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet Infect Dis. 2020;20:559–564. [cited 2020 Apr 8]. Available from: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30176-6/abstract
   Google Scholar
• Li N, Han L, Peng M, et al. Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study. Clin Infect Dis. 2020;ciaa352. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa352/5813589
   Google Scholar
• Zaigham M, Andersson O. Maternal and perinatal outcomes with COVID-19: a systematic review of 108 pregnancies. Acta Obstet Gynecol Scand. 2020. DOI:10.1111/aogs.13867
   Google Scholar
• Qiancheng X, Jian S, Lingling P, et al. Coronavirus disease 2019 in pregnancy. Int J Infect Dis. 2020;95:376–383.
   Google Scholar
• Panahi L, Amiri M, Pouy S. Risks of novel coronavirus disease (COVID-19) in pregnancy; a narrative review. Arch Acad Emerg Med. 2020;8:e34.
   Google Scholar
• Baud D, Greub G, Favre G, et al. Second-trimester miscarriage in a pregnant woman with SARS-CoV-2 infection. JAMA. 2020; 323(21): 2198–2200 .
   Google Scholar
• Memoli MJ, Harvey H, Morens DM, et al. Influenza in pregnancy. Influenza Other Respir Viruses. 2013;7:1033–1039.
   Google Scholar
• Chen D, Yang H, Cao Y, et al. Expert consensus for managing pregnant women and neonates born to mothers with suspected or confirmed novel coronavirus (COVID-19) infection. Int J Gynaecol Obstet. 2020;149:130–136.
   Google Scholar
• Schwartz DA. An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: maternal coronavirus infections and pregnancy outcomes. Arch Pathol Lab Med. 2020;149:130–136.
   Google Scholar
• Kirtsman M, Diambomba Y, Poutanen SM, et al. Probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection. Can Med Assoc J. 2020. DOI:10.1503/cmaj.200821
   Google Scholar
• Dong L, Tian J, He S, et al. Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn. JAMA. 2020;323: 1846–148.
   Google Scholar
• Zeng H, Xu C, Fan J, et al. Antibodies in infants born to mothers with COVID-19 pneumonia. JAMA. 2020;323:1848–1849.
   Google Scholar
• Kimberlin DW, Stagno S. Can SARS-CoV-2 infection be acquired in utero? More definitive evidence is needed. JAMA. 2020. DOI:10.1001/jama.2020.4868
   Google Scholar
• World Health Organization. Q&A on COVID-19, pregnancy, childbirth and breastfeeding. [cited 2020 Apr 4]. Available from: https://www.who.int/news-room/q-a-detail/q-a-on-covid-19-pregnancy-childbirth-and-breastfeeding
   Google Scholar
• FAQs: management of infants born to mothers with suspected or confirmed COVID-19. [cited 2020 May 25]. Available from: http://services.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections/faqs-management-of-infants-born-to-covid-19-mothers/
   Google Scholar
• Zhi C, Hao X, Jianxin L, et al. COVID-19 with post-chemotherapy agranulocytosis in childhood acute leukemia: a case report. Chin J Hematol. 2020;41:341–343.
   Google Scholar
• Sieni E, Pegoraro F, Casini T, et al. Favourable outcome of coronavirus disease 2019 in a 1-year-old girl with acute myeloid leukaemia and severe treatment-induced immunosuppression. Br J Haematol. 2020. Online publication ahead of print. DOI:10.1111/bjh.16781
   Google Scholar
• Balduzzi A, Brivio E, Rovelli A, et al. Lessons after the early management of the COVID-19 outbreak in a pediatric transplant and hemato-oncology center embedded within a COVID-19 dedicated hospital in Lombardia, Italy. Estote parati. Bone Marrow Transplant. 2020;1–6. DOI:10.1038/s41409-020-0895-4
   Google Scholar
• Hrusak O, Kalina T, Wolf J, et al. Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment. Eur J Cancer. 2020;132:11–16.
   Google Scholar
• Boulad F, Kamboj M, Bouvier N, et al. COVID-19 in children with cancer in New York City. JAMA Oncol. 2020;e202028. https://jamanetwork.com/journals/jamaoncology/fullarticle/2766112
   Google Scholar
• de Rojas T, Pérez‐Martínez A, Cela E, et al. COVID-19 infection in children and adolescents with cancer in Madrid. Pediatr Blood Cancer. 2020;e28397. https://pubmed.ncbi.nlm.nih.gov/32383819/
   Google Scholar
• D’Antiga L. Coronaviruses and immunosuppressed patients: the facts during the third epidemic. Liver Transpl. 2020;26:832–834.
   Google Scholar
• Zhong Z, Zhang Q, Xia H, et al. Clinical characteristics and immunosuppressant management of coronavirus disease 2019 in solid organ transplant recipients. Am J Transplant. 2020. Online publication ahead of print. DOI:10.1111/ajt.15928
   Google Scholar
• Minotti C, Tirelli F, Barbieri E, et al. How is immunosuppressive status affecting children and adults in SARS-CoV-2 infection? A systematic review. J Infect. 2020;S0163-4453(20):30237–1.
   Google Scholar
• André N, Rouger‐Gaudichon J, Brethon B, et al. COVID-19 in pediatric oncology from French pediatric oncology and hematology centers: high risk of severe forms? Pediatr Blood Cancer. 2020;67:e28392.
   Google Scholar
• Bouffet E, Challinor J, Sullivan M, et al. Early advice on managing children with cancer during the COVID-19 pandemic and a call for sharing experiences. Pediatr Blood Cancer. 2020;67:e28327.
   Google Scholar
• Bayham J, Fenichel EP. Impact of school closures for COVID-19 on the US health-care workforce and net mortality: a modelling study. Lancet Public Health. 2020;5:e271–e278.
   Google Scholar
• Viner RM, Russell SJ, Croker H, et al. School closure and management practices during coronavirus outbreaks including COVID-19: a rapid systematic review. Lancet Child Adolesc Health. 2020;4:397–404.
   Google Scholar
• Centers for Disease Control and Prevention. SARS response timeline. 2018 [cited 2020 Apr 9]. Available from: https://www.cdc.gov/about/history/sars/timeline.htm
   Google Scholar
• Peiris JSM, Chu CM, Cheng VCC, et al. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767–1772.
   Google Scholar
• Lipsitch M, Cohen T, Cooper B, et al. Transmission dynamics and control of severe acute respiratory syndrome. Science. 2003;300:1966–1970.
   Google Scholar
• Esposito S, Principi N. To mask or not to mask children to overcome COVID-19. Eur J Pediatr. 2020;1–4. DOI:10.1007/s00431-020-03674-9
   Google Scholar
• Rasmussen SA, Thompson LA. Coronavirus disease 2019 and children: what pediatric health care clinicians need to know. JAMA Pediatr;2020. Online publication ahead of print. DOI:10.1001/jamapediatrics.2020.1224
   Google Scholar
• Bradbury‐Jones C, Isham L. The pandemic paradox: the consequences of COVID-19 on domestic violence. J Clin Nurs;2020. Online publication ahead of print. DOI:10.1111/jocn.15296
   Google Scholar
• Mahase E. Covid-19: EU states report 60% rise in emergency calls about domestic violence. Br Med J. 2020;369:m1872.
   Google Scholar
• Mazza M, Marano G, Lai C, et al. Danger in danger: interpersonal violence during COVID-19 quarantine. Psychiatry Res. 2020;289:113046.
   Google Scholar
• Liu JJ, Bao Y, Huang X, et al. Mental health considerations for children quarantined because of COVID-19. Lancet Child Adolesc Health. 2020;4:347–349.
   Google Scholar
• Fegert JM, Vitiello B, Plener PL, et al. Challenges and burden of the Coronavirus 2019 (COVID-19) pandemic for child and adolescent mental health: a narrative review to highlight clinical and research needs in the acute phase and the long return to normality. Child Adolesc Psychiatry Ment Health. 2020;14:20.
   Google Scholar
• Golberstein E, Wen H, Miller BF. Coronavirus disease 2019 (COVID-19) and mental health for children and adolescents. JAMA Pediatr;2020. Online publication ahead of print. DOI:10.1001/jamapediatrics.2020.1456
   Google Scholar
• COVID-19 Clinical Guidance Q & A. [cited 2020 Apr 10]. Available from: http://services.aap.org/en/pages/covid-19-clinical-guidance-q-a/
   Google Scholar
• Santoli JM. Effects of the COVID-19 pandemic on routine pediatric vaccine ordering and administration – United States 2020. MMWR. 2020 [cited 2020 May 23]. Available from: https://www.cdc.gov/mmwr/volumes/69/wr/mm6919e2.htm
   Google Scholar
• World Health Organization. Healthy parenting. [cited 2020 Apr 9]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/advice-for-public/healthy-parenting
   Google Scholar
• Positive parenting & COVID-19: 10 tips to help keep the calm at home. HealthyChildren.org. [cited 2020 Apr 9]. Available from: https://www.healthychildren.org/English/family-life/family-dynamics/communication-discipline/Pages/Positive-Parenting-and-COVID-19_10-Tips.aspx
   Google Scholar