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Pathogens and Global Health Volume 110, 2016 - Issue 7-8
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Short Communication

Para-kala-azar dermal Leishmaniasis cases in Indian subcontinent – A case series

Rakesh KumarDepartment of Clinical Medicine, Rajendra Memorial Research Institute of Medical Sciences (Indian Council of Medical Research), Patna, India
,
Vidya Nand Rabi DasDepartment of Clinical Medicine, Rajendra Memorial Research Institute of Medical Sciences (Indian Council of Medical Research), Patna, India
,
Roshan Kamal TopnoDepartment of Epidemiology, Rajendra Memorial Research Institute of Medical Sciences (Indian Council of Medical Research), Patna, India
,
Biplab PalDepartment of Pharmacy Practice, National Institute of Pharmaceutical Education and Research, Hajipur, India
,
Adnan ImamDepartment of Clinical Medicine, Rajendra Memorial Research Institute of Medical Sciences (Indian Council of Medical Research), Patna, India
,
Kanhaiya AgrawalDepartment of Clinical Medicine, Rajendra Memorial Research Institute of Medical Sciences (Indian Council of Medical Research), Patna, India
,
Anima SinghDepartment of Clinical Medicine, Rajendra Memorial Research Institute of Medical Sciences (Indian Council of Medical Research), Patna, India
,
Krishna MurtiDepartment of Pharmacy Practice, National Institute of Pharmaceutical Education and Research, Hajipur, India
,
Chandra Shekhar LalDepartment of Clinical Biochemistry, Rajendra Memorial Research Institute of Medical Sciences (Indian Council of Medical Research), Patna, India
,
Neena VermaDepartment of Pathology, Rajendra Memorial Research Institute of Medical Sciences (Indian Council of Medical Research), Patna, India
,
Pradeep DasDepartment of Molecular Biology, Rajendra Memorial Research Institute of Medical Sciences (Indian Council of Medical Research), Patna, India
&
Krishna PandeyDepartment of Clinical Medicine, Rajendra Memorial Research Institute of Medical Sciences (Indian Council of Medical Research), Patna, IndiaCorrespondence[email protected]
 show all
Pages 326-329 | Published online: 22 Nov 2016

References

  • Akhoundi M, Kuhls K, Cannet A, Votýpka J, Marty P, Delaunay P, et al. A historical overview of the classification, evolution, and dispersion of Leishmania parasites and sandflies. PLOS Neglected Trop Dis. 2016;10(3):e0004349. doi:10.1371/journal.pntd.0004349.
  • Ramirez, JD, Hernandez, C, Cielo M, Ayala, MS, Florez, C, Camila Gonzalez. Taxonomy, diversity, temporal and geographical distribution of Cutaneous Leishmaniasis in Colombia: a retrospective study. Sci Rep. 2016;6. doi:10.1038/srep28266
  • Ramesh V, Mukherjee A. Post-kala-azar dermal leishmaniasis. Int J Dermatol. 1995;34(2):85–91.10.1111/ijd.1995.34.issue-2
  • Mukhopadhyay D, Dalton JE, Kaye PM, Chatterjee M. Post kala-azar dermal Leishmaniasis: an unresolved mystery. Trends Parasitol. 2014;30(2):65–74.10.1016/j.pt.2013.12.004
  • Nandy A, Addy M, Maji AK, Guha SK, Banerjee D, Chaudhuri D. Recurrence of kala-azar after PKDL: role of co-factors. Trop Med Int Health. 1998;3(1):76–78.10.1046/j.1365-3156.1998.00176.x
  • Zijlstra EE, Musa AM, Khalil EA, el-Hassan IM, el-Hassan AM. Post-kala-azar dermal leishmaniasis. Lancet Infect Dis. 2003;3(2):87–98.10.1016/S1473-3099(03)00517-6
  • Das VNR, Pandey K, Verma N, Lal CS, Bimal S, Topno RK, et al. Short report: development of post-kala-azar dermal Leishmaniasis (PKDL) in miltefosine- treated visceral Leishmaniasis. Am J Trop Med Hyg. 2009;80(3):336–338.
  • Islam S, Kenah E, Bhuiyan MAA, Rahman KM, Goodhew B, Ghalib CM, et al. Clinical and immunological aspects of post-kala-azar dermal Leishmaniasis in Bangladesh. Am J Trop Med Hyg. 2013;89(2):345–353.10.4269/ajtmh.12-0711
  • Ansari NA, Ramesh V, Salotra P. Interferone(IFN)-γ, tumor necrosis factor- α, interleukin-6, and INF-γ receptor 1 are the major immunological determinants associated with post -kala-azar dermal Leishmaniasis. J Infect Dis. 2006;194(7):958–965.10.1086/jid.2006.194.issue-7
  • Gasim S, El Hassan AM, Khalil EAG, Ismail A, Kadaru A, Kharazmi A, et al. High-levels of plasma interleukin-10 and expression of interleukin-10 by keratinocytes during visceral Leishmaniasis predict subsequent development of PKDL. Clin Exp Immunol. 1998;111(1):64–69.10.1046/j.1365-2249.1998.00468.x
  • Ganguly S, Mukhopadhyay D, Das NK, Chaduvula M, Sadhu S, Chatterjee U, et al. Enhanced lesional Foxp3 expression and peripheral anergic lymphocytes indicate a role for regulatory T cells in Indian post-kala-azar dermal Leishmaniasis. J Invest Dermatol. 2010;130(4):1013–1022.10.1038/jid.2009.393
  • Ganguly S, Das NK, Panja M, Pal S, Modak D, Rahaman M, et al. Increased levels of Interleukin-10 and IgG3 are hallmark of Indian postkalazar dermal Leishmaniasis. J Infect Dis. 2008;197(12):1762–1771.10.1086/590464
  • Zijlstra, EE. PKDL and other dermal lesion in HIV co-infected patient with Leishmaniasis: review of clinical presentation in relation to immune responses. PLOS Neglected Trop Dis. 2014. 8(11):e3258. doi:10.1371/journal.pntd.0003258
  • French MA, Price P, Stone SF. Immune restoration disease after antiretroviral therapy. AIDS. 2004;18(12):1615–1627.10.1097/01.aids.0000131375.21070.06
  • Gelanew T, Hurissa Z, Diro E, Kassahun A, Kuhls K, Schonian G, et al. Disseminated Cutaneous Leishmaniasis resembling PKDL caused by leishmania donavani in three patients co-infected with VL and human immunodeficiency virus/AIDS in Ethiopia. Am J Trop Med Hyg. 2011;84(6):906–912.10.4269/ajtmh.2011.11-0055
  • Shamsuzzaman AKM, Mahmud MC, Akhter S, Musa AKM, Hossain, A. LD bodies from blood buffy coat: an easy approach for definitive diagnosis of Visceral Leishmaniasis. Bangladesh J Med Microbiol. 2007;1(2):43–47.
  • Sharma MC, Gupta AK, Verma N, Das VN, Saran R, Kar SK. Demonstration of Leishmania Parasites in skin lesions of Indian post-kala-azar dermal leishmaniasis (PKDL) cases. J Commun Dis. 2000;32:67–68.
  • Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J. Harrison’s principle of internal medicine. 2015. p. 1387–1393.
  • Salotra P, Duncan RC, Singh R, Subha Raju BV, Sreenivas G, Nakhasi HL. Upregulation of surface proteins in Leishmania donovani isolated from patients of post kala-azar dermal leishmaniasis. Microbes Infect. 2006;8(3):637–644.10.1016/j.micinf.2005.08.018
  • Van Griensven J, Boelaert M. Combination therapy of visceral Leishmaniasis. Lancet. 2011;377(9764):443–444.10.1016/S0140-6736(10)62237-4
  • Mubi RR, Lodenyo H, Nyakundi P, Kipmutai R, Mutuma G, Kirigi G, et al. Visceral leishmaniasis with concomittant post kala-azar dermal leishmaniasis responds to oral sitamaquine: case report. East Afr Med J. 2003;80(3):440–443.
  • Chulay JD, Bryceson AD. Quantitation of amastigotes of Leishmania donovani in smears of splenic aspirates from patients with visceral leishmaniasis. Am J Trop Med Hyg. 1983;32:475–479.

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