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Research Article

The suppressor of cytokine signaling-1 (SOCS1) gene polymorphism and promoter methylation correlate with the course of COVID-19

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References

  • https://covid19.who.int/ (last cited: [date:28.11.2022])
  • Wu C, Chen X, Cai Y, et al. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA Intern Med. 2020 Jul 1;180(7):934–943. DOI:10.1001/jamainternmed.2020.0994.
  • Guan WJ, Ni ZY, Hu Y, et al. China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020 Apr 30;382(18):1708–1720. DOI:10.1056/NEJMoa2002032.
  • Cai Q, Chen F, Wang T, et al. Obesity and COVID-19 severity in a designated hospital in Shenzhen, China. Diabetes Care. 2020 Jul;43(7):1392–1398.
  • Centers for Disease Control and Prevention. People who are at higher risk for severe illness. 2020 [cited 2020 April 8]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/need-extraprecautions/people-at-higher-risk.html
  • Guedes RA, Planello AC, Andia DC, et al. Association of SOCS1 (- 820) (rs33977706) gene polymorphism with chronic periodontitis: a case‒control study in Brazilians. Meta Gene. 2015 Jul 9;5:124–128. DOI:10.1016/j.mgene.2015.06.005.
  • Harada M, Nakashima K, Hirota T, et al. Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma. Am J Respir Cell Mol Biol. 2007 Apr;36(4):491–496.
  • Brand S, Zitzmann K, Dambacher J, et al. SOCS-1 inhibits expression of the antiviral proteins 2‘,5’-OAS and MxA induced by the novel interferon-lambdas IL-28A and IL-29. Biochem Biophys Res Commun. 2005 Jun 3;331(2):543–548. DOI:10.1016/j.bbrc.2005.04.004.
  • Duncan BK, Miller JH. Mutagenic deamination of cytosine residues in DNA. Nature. 1980;287(5782):560–561.
  • Fazzari MJ, Greally JM. Epigenomics: beyond CpG islands. Nat Rev Genet. 2004 Jun;5(6):446–455. DOI:10.1038/nrg1349.
  • Cross SH, Bird AP. CpG islands and genes. Curr Opin Genet Dev. 1995 Jun;5(3):309–314. DOI:10.1016/0959-437x(95)80044-1.
  • Chan MW, Chu ES, To KF, et al. Quantitative detection of methylated SOCS-1, a tumor suppressor gene, by a modified protocol of quantitative real time methylation-specific PCR using SYBR green and its use in early gastric cancer detection. Biotechnol Lett. 2004 Aug;26(16):1289–1293. DOI:10.1023/B:BILE.0000044922.43572.2d.
  • Ozen Oz G, Soner C, Cuma B, et al. Cytokine signal suppressor (SOCS) 1-1478 CA/del gene polymorphism in Turkish patients with polycystic ovary syndrome. J Obstet Gynaecol. 2017. DOI:10.1080/01443615.2017.1309011)
  • Li B, Chen X, Jiang Y, et al. CCL2 promoter hypomethylation is associated with gout risk in Chinese Han male population. Immunol Lett. 2017;190:15–19.
  • Ma H, Chen X, Hu H, et al. Hypermethylation of MDFI promoter with NSCLC is specific for females, nonsmokers and people younger than 65. Oncol Lett. 2018 Jun;15(6):9017–9024. DOI:10.3892/ol.2018.8535.
  • Sarabi MM, Naghibalhossaini F. Association of DNA methyltransferases expression with global and gene-specific DNA methylation in colorectal cancer cells. Cell Biochem Funct. 2015 Oct;33(7):427–433. DOI:10.1002/cbf.3126.
  • Duncan SA, Baganizi DR, Sahu R, et al. SOCS proteins as regulators of inflammatory responses induced by bacterial infections: a review. Front Microbiol. 2017 Dec 12;8:2431. DOI:10.3389/fmicb.2017.02431.
  • Ward AC, Touw I, Yoshimura A. The Jak-Stat pathway in normal and perturbed hematopoiesis. Blood. 2000 Jan 1;95(1):19–29.
  • Galm O, Yoshikawa H, Esteller M, et al. SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma. Blood. 2003 Apr 1;101(7):2784–2788.
  • Akhtar L, Benveniste E. Viral exploitation of host SOCS protein functions. J Virol. 2010;85(5):1912‐1921.
  • Zheng J, Yang P, Tang Y, et al. Respiratory syncytial virus nonstructural proteins upregulate SOCS1 and SOCS3 in the different manner from endogenous IFN signaling. J Immunol Res. 2015;2015:1‐11.
  • Xu X, Zheng J, Zheng K, et al. Respiratory syncytial virus NS1 protein degrades STAT2 by inducing SOCS1 expression. Intervirology. 2014;57(2):65‐73.
  • Seong R, Lee J, Shin O. Zika virus‐induction of the suppressor of cytokine signaling 1/3 contributes to the modulation of viral replication. Pathogens. 2020;9(3):163.
  • Low ZY, Wen Yip AJ, Chow VTK, et al. The suppressor of cytokine signaling family of proteins and their potential impact on COVID-19 disease progression. Rev Med Virol. 2021 Sep 21;32(3):e2300.
  • Xu G, Yang F, Ding CL, et al. MiR-221 accentuates IFN׳s anti-HCV effect by downregulating SOCS1 and SOCS3. Virology. 2014 Aug;462-463:343–350. DOI:10.1016/j.virol.2014.06.024.
  • Frey KG, Ahmed CM, Dabelic R, et al. HSV-1-induced SOCS-1 expression in keratinocytes: use of a SOCS-1 antagonist to block a novel mechanism of viral immune evasion. J Immunol. 2009 Jul 15;183(2):1253–1262. DOI:10.4049/jimmunol.0900570.
  • Johnson HM, Lewin AS, Ahmed CM. SOCS, intrinsic virulence factors, and treatment of COVID-19. Front Immunol. 2020 Oct 23;11:582102. DOI:10.3389/fimmu.2020.582102.
  • Satarker S, Tom AA, Shaji RA, et al. JAK-STAT pathway inhibition and their implications in COVID-19 therapy. Postgrad Med. 2021 Jun;133(5):489–507. DOI:10.1080/00325481.2020.1855921.
  • Soy M, Keser G, Atagündüz P, et al. Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment. Clin Rheumatol. 2020 Jul;39(7):2085–2094. DOI:10.1007/s10067-020-05190-5.
  • Jorgensen SCJ, Tse CLY, Burry L, et al. Baricitinib: a review of pharmacology, safety, and emerging clinical experience in COVID-19. Pharmacotherapy. 2020 Aug;40(8):843–856. DOI:10.1002/phar.2438.

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