The relation between plasma apelin 36 and insulin resistance in obese type 2 diabetic Egyptian population

References

• Cheema A, Adeloye D, Sridhar D, et al. Urbanization and prevalence of type 2 diabetes in southern Asia: a systemic analysis. J Global Health. 2014 jun;4(1):016404.
   Web of Science ®Google Scholar
• International Diabetes Federation. One adult in ten will have diabetes by 2021. Diabetes atlas. 10 th ed.
   Google Scholar
• Bos M, Chareles A. Prevalence and complications of diabetes mellitus in north Africa; a systemic review. BMC Public Health. 2013;13(1):387. doi: 10.1186/1471-2458-13-387
   PubMedGoogle Scholar
• Unger RH, Orci L. Of islets and paracrinopathy of diabetes. Proc Nah Academy Sci USA. 2010 Sep 14;107(37):16009–16012.
   PubMed Web of Science ®Google Scholar
• Basha F, Lee S, Gungor N, et al. From prediabetes to type 2 diabetes in obese youth: diabetes care. Diabetes Care. 2010 Oct;33(10):2225–2231. doi: 10.2337/dc10-0004
   PubMed Web of Science ®Google Scholar
• Lee SH, Park SA, Yim HW, et al. Insulin resistance and inflammation. Metbolism. 2010 Feb;59(2):241–246.
   PubMedGoogle Scholar
• Brabant G, Muller G, Horn R, et al. Hepatic leptin signaling in obesity. FASEB J. 2005 Jan;19(8):1048–1050.
   PubMedGoogle Scholar
• Fuke Y, Fujita T, Satoomura A, et al. Alterations of insulin resistance and serum adiponectin. Diabetes Technol Ther. 2010 May;12(5):393–398. doi: 10.1089/dia.2009.0126
   PubMed Web of Science ®Google Scholar
• Florez H, Castillo-Florez S, Mendez A, et al. C reactive protein is elevated in obese patients with metabolic syndrome. Diabet Res Clin Pract. 2006 Jan;71(1):92–100.
   PubMed Web of Science ®Google Scholar
• Meyers JA, Liu AY. Serum leptin concentrations and markers of immune function in overwight. J Endocrinol. 2008;199(1):51–60. doi: 10.1677/JOE-07-0569
   PubMed Web of Science ®Google Scholar
• Matsuzawa Y. Adiponectin: identification, physiology and clinical relevance. Atherosclerosis Suppl. 2005;6(2):7–14. doi: 10.1016/j.atherosclerosissup.2005.02.003
   PubMed Web of Science ®Google Scholar
• Kunduzora O, Alet N, Delesque T, et al. Apelin/APJ signaling system: a potential link between adipose tissue and endothelial angiogenic processes. FASEB J. 2008;22(12):4146–4153. doi: 10.1096/fj.07-104018
   PubMed Web of Science ®Google Scholar
• Kleinz MJ, Davenport A. Emerging roles of apelinin biology and medicine. Pharmacol Ther. 2005;107(2):198–211. doi: 10.1016/j.pharmthera.2005.04.001
   PubMed Web of Science ®Google Scholar
• Soriguer F, Garrido L, Garcia-Serrano, S et al. Apelin levels are increased in morbidly obese subjects with T2DM. Obese Sur. 2005 Nov;19(11):1574–1580.
   Google Scholar
• Dray C, Knauf C, Davioud D, et al. Apelin stimulates glucose utilization in normal and obese insulin resistant mice. Cell Metab. 2008;8(5):437–454. doi: 10.1016/j.cmet.2008.10.003
   PubMed Web of Science ®Google Scholar
• Mohiti J, Doudi Q. Relation between leptin and insulin in patients with type 2 DM. Turk J Endocrinol Metab. 2005;2:55–58.
   Google Scholar
• Passaro A, Calzani F, Pier F, et al. Eur J Endocrinol. 2001;45:173–179. doi: 10.1530/eje.0.1450173
   Google Scholar
• Moller M, Peter O, Nair, KS et al. Disruption of the relationship between fat content and leptin levels with aging in humans. J Clin Endocrinol Metab. 1998;83(3):931–934. doi: 10.1210/jc.83.3.931
   PubMed Web of Science ®Google Scholar
• Williams I, Sivitiz S, Wayson M. Leptin and body fat in type 2 diabetes and monodrug therapy. J Clin Endocrinol Metab. 2003;88(4):1543–1553. doi: 10.1210/jc.2002-021193
   PubMed Web of Science ®Google Scholar
• Masoud Y, Adel A. Correlation between serum leptin levels BMI and obesity in omanis. Med J. 2006 Dec;6:27–31.
   Google Scholar
• Yukio A, Shinji K, Masahiko T, et al. Adiponectin in obesity. Bioch & Biophy Reas. 1999 April;127:79–83.
   Google Scholar
• Halleux CM, Takashi M, Detry MR, et al. Secretion of Adiponectin and regulation of apM1 gene expression in human visceral adipose tissue. Biochem Biophys Res Commun. 2001;11(5):1102–1107. doi: 10.1006/bbrc.2001.5904
   Google Scholar
• Yu S, Zhang Y, Li R, et al. Chemerin and apelin are positively correlated with inflammation in obese type2DM. Clin Med J (Engl). 2012;125(19):40–44.
   Web of Science ®Google Scholar
• Heinonen MV, Purhonin AK, Miettinen, P, et al. Apelin, orexin-A and leptin plasma levels in morbid obesity and effect of gastric banding. Regul Pept. 2005 Aug;130(1–2):7–13.
   PubMedGoogle Scholar
• Gisella M, Federico S, Slaric B. Altered glucose homeostasis is associated with increased serum apelin in T2DM. First Author Cavallo GM. 2012;7(12):e51236.
   Google Scholar
• Attane C, Daviaud D, Dray C, et al. Apelin stimulate glucose uptake. J Mol Endocrinol. 2011;26:21–28.
   Google Scholar
• Attane C, Foussal C, Le Gonidec S, et al. Apelin treatment increases fatty acid oxidation. Diabetes. 2012;61(2):310–320. doi: 10.2337/db11-0100
   PubMed Web of Science ®Google Scholar