Impact of body mass index on semen parameters and reproductive hormones among men undergoing microsurgical subinguinal varicocelectomy

References

• Clarke BG. Incidence of varicocele in normal men and among men of different ages. JAMA. 1966;198(10):1121–1122.
   PubMed Web of Science ®Google Scholar
• Arya D, Balasinor N, Singh D. Varicocele-associated male infertility: cellular and molecular perspectives of pathophysiology. Andrology. 2022;10(8):1463–1483.
   PubMed Web of Science ®Google Scholar
• Guo D, Wu W, Tang Q, et al. The impact of BMI on sperm parameters and the metabolite changes of seminal plasma concomitantly. Oncotarget. 2017;8(30):48619–48634. DOI:10.18632/oncotarget.14950
   PubMedGoogle Scholar
• Hammoud A, Wilde N, Gibson M, et al. Male obesity and alteration in sperm parameters. Fertil Steril. 2008;90(6):2222–2225. DOI:10.1016/j.fertnstert.2007.10.011
   PubMed Web of Science ®Google Scholar
• HI K, JB M, CW E, et al. Impact of body mass index values on sperm quantity and quality. J Androl. 2006;27(3):450–452.
   PubMedGoogle Scholar
• Leisegang K, Sengupta P, Agarwal A, et al. Obesity and male infertility: mechanisms and management. Andrologia. 2021;53(1):e13617. DOI:10.1111/and.13617
   PubMed Web of Science ®Google Scholar
• Jensen CFS, Østergren P, Dupree JM, et al. Varicocele and male infertility. Nat Rev Urol. 2017;14(9):523–533. DOI:10.1038/nrurol.2017.98
   PubMed Web of Science ®Google Scholar
• Agarwal A, Cannarella R, Saleh R, et al. Impact of varicocele repair on semen parameters in infertile men: a systematic review and meta-analysis. World J Mens Health. 2022. DOI:10.5534/wjmh.220142
   Google Scholar
• Majzoub A, ElBardisi H, Covarrubias S, et al. Effect of microsurgical varicocelectomy on fertility outcome and treatment plans of patients with severe oligozoospermia: an original report and meta-analysis. Andrologia. 2021;53(6):e14059. DOI:10.1111/and.14059
   PubMed Web of Science ®Google Scholar
• Birowo P, Tendi W, Widyahening IS, et al. The benefits of varicocele repair for achieving pregnancy in male infertility: a systematic review and meta-analysis. Heliyon. 2020;6(11):e05439. DOI:10.1016/j.heliyon.2020.e05439
   PubMed Web of Science ®Google Scholar
• Kandevani NY, Namdari F, Hamidi M, et al. Developing a novel prediction model for the impact of varicocelectomy on postoperative fertility. Eur J Trans Myol. 2022;32(2):10411. DOI:10.4081/ejtm.2022.10411
   PubMed Web of Science ®Google Scholar
• Ates E, Ucar U, Keskin MZ, et al. Preoperative neutrophil-to-lymphocyte ratio as a new prognostic predictor after microsurgical subinguinal varicocelectomy. Andrologia. 2019;51(2):e13188. DOI:10.1111/and.13188
   PubMed Web of Science ®Google Scholar
• Shabana W, Teleb M, Dawod T, et al. Predictors of improvement in semen parameters after varicocelectomy for male subfertility: a prospective study. Can Urol Assoc J. 2015;9(9–10):E579–582. DOI:10.5489/cuaj.2808
   PubMed Web of Science ®Google Scholar
• Chen S-S, Chen L. Predictive factors of successful varicocelectomy in infertile patients. Urol Int. 2011;86(3):320–324.
   PubMed Web of Science ®Google Scholar
• Pham KN, Sandlow J. The effect of body mass index on the outcomes of varicocelectomy. J Urol. 2012;187(1):219–221.
   PubMed Web of Science ®Google Scholar
• Abou Ghayda R, El-Doueihi RZ, Lee JY, et al. Anthropometric variables as predictors of semen parameters and fertility outcomes after varicocelectomy. J Clin Med. 2020;9(4):1160. DOI:10.3390/jcm9041160
   PubMed Web of Science ®Google Scholar
• El-Dighidy MA, Sherief MH, Shamaa MA, et al. Smoking and obesity negatively affect the favorable outcome of varicocelectomy in sub-fertile men. Andrologia. 2021;53(8):e14131. DOI:10.1111/and.14131
   PubMed Web of Science ®Google Scholar
• Ahmad R, Haque M. Obesity: a doorway to a molecular path leading to infertility. Cureus. 2022;14(10):e30770. DOI:10.7759/cureus.30770.
   PubMed Web of Science ®Google Scholar
• Chaudhuri GR, Das A, Kesh SB, et al. Obesity and male infertility: multifaceted reproductive disruption. Middle East Fertil Soc J. 2022;27(1):8. DOI:10.1186/s43043-022-00099-2
   Web of Science ®Google Scholar
• WHO. Physical status: the use and interpretation of anthropometry: report of a World Health Organization (WHO) expert committee. Geneva, Switzerland: World Health Organization; 1995.
   Google Scholar
• Cooper TG, Noonan E, von Eckardstein S, et al. World Health Organization reference values for human semen characteristics*‡. Human Reproduction Update. 2010;16(3):231–245. DOI:10.1093/humupd/dmp048
   PubMed Web of Science ®Google Scholar
• Fernandez JL, Muriel L, Rivero MT, et al. The sperm chromatin dispersion test: a simple method for the determination of sperm DNA fragmentation. J Androl. 2003;24(1):59–66.
   PubMedGoogle Scholar
• Agarwal A, Roychoudhury S, Sharma R, et al. Diagnostic application of oxidation-reduction potential assay for measurement of oxidative stress: clinical utility in male factor infertility. Reprod Biomed Online. 2017;34(1):48–57. DOI:10.1016/j.rbmo.2016.10.008
   PubMed Web of Science ®Google Scholar
• Agarwal A, Arafa M, Chandrakumar R, et al. A multicenter study to evaluate oxidative stress by oxidation-reduction potential, a reliable and reproducible method. Andrology. 2017;5(5):939–945. DOI:10.1111/andr.12395
   PubMed Web of Science ®Google Scholar
• Majzoub A, Elbardisi H, Arafa M, et al. Does the number of veins ligated during varicocele surgery influence post-operative semen and hormone results? Andrology. 2016;4(5):939–943. DOI:10.1111/andr.12226
   PubMed Web of Science ®Google Scholar
• Hassanzadeh-Nokashty K, Yavarikia,P, C, Hazhir, S, Hassanzadeh, M. Effect of age on semen parameters in infertile men after varicocelectomy. Ther Clin Risk Manag. 2011;7:333–6. DOI:10.2147/TCRM.S17027. Epub 2011 Aug 9. PMID: 21941438; PMCID: PMC3176165
   PubMedGoogle Scholar
• Bolat MS, Kocamanoglu F, Gulsen M, Sengul, M, Asci, R. The impact of age on fertility rate in patients who underwent microsurgical varicocelectomy. Andrologia. 2019;51(4):e13234. DOI:10.1111/and.13234. Epub 2019 Jan 28. PMID: 30689241
   PubMed Web of Science ®Google Scholar
• Zhang H, Liu X-P, Yang X-J, et al. Loupe-assisted versus microscopic varicocelectomy: is there an intraoperative anatomic difference? Asian J Androl. 2014;16(1):112–114. DOI:10.4103/1008-682X.122189
   PubMed Web of Science ®Google Scholar
• Asafu-Adjei D, Judge C, Deibert CM, et al. Systematic review of the impact of varicocele grade on response to surgical management. J Urol. 2020;203(1):48–56. DOI:10.1097/JU.0000000000000311
   PubMed Web of Science ®Google Scholar
• Zohdy W, Ghazi S, Arafa M. Impact of varicocelectomy on gonadal and erectile functions in men with hypogonadism and infertility. J Sex Med. 2011;8(3):885–893.
   PubMed Web of Science ®Google Scholar
• Ghaed MA, Makian SA, Moradi A, Maghsoudi, R, Gandomi-, Mohammadabadi A, et al. Best time to wait for the improvement of the sperm parameter after varicocelectomy: 3 or 6 months? Arch Ital Urol Androl. 2020;92(3). DOI:10.4081/aiua.2020.3.259. PMID: 33016058
   PubMedGoogle Scholar
• Machen GL, Johnson D, Nissen MA, et al. Time to improvement of semen parameters after microscopic varicocelectomy: when it occurs and its effects on fertility. Andrologia. 2020;52(2):e13500. DOI:10.1111/and.13500
   PubMed Web of Science ®Google Scholar
• Jorgensen N, Auger J, Giwercman A, et al. Semen analysis performed by different laboratory teams: an intervariation study. Int J Androl. 1997;20(4):201–208. DOI:10.1046/j.1365-2605.1997.00052.x
   PubMedGoogle Scholar
• Mehta A, Goldstein M. Microsurgical varicocelectomy: a review. Asian J Androl. 2013;15(1):56–60.
   PubMed Web of Science ®Google Scholar