Telling the Truth About Pain: Informed Consent and the Role of Expectation in Pain Intensity

REFERENCES

• Ader, R. 2000. Classical conditioning in the treatment of psoriasis. Cutis 66(5): 370–372.
   PubMed Web of Science ®Google Scholar
• Alfano, M. 2015. Placebo effects and informed consent. American Journal of Bioethics 15(10): 3–12. doi:10.1080/15265161.2015.1074302
   PubMed Web of Science ®Google Scholar
• Annoni, M., and F. G. Miller. 2016. Placebo effects and the ethics of therapeutic communication: A pragmatic perspective. Kennedy Institute of Ethics Journal 26(1): 79–103.
   PubMed Web of Science ®Google Scholar
• Arntz, A., and L. Claassens. 2004. The meaning of pain influences its experienced intensity. Pain 109(1): 20–25. doi:10.1016/j.pain.2003.12.030
   PubMed Web of Science ®Google Scholar
• Beauchamp, T. L., and J. F. Childress. 2009. Principles of biomedical ethics. (6th ed.). New York: Oxford University Press.
   Google Scholar
• Bingel, U., V. Wanigasekera, K. Wiech, et al. 2011. The effect of treatment expectation on drug efficacy: Imaging the analgesic benefit of the opioid remifentanil. Science Translational Medicine 3(70): 70ra14. doi:10.1126/scitranslmed.3001244
   PubMed Web of Science ®Google Scholar
• Boerner, K. E., K. A. Birnie, C. T. Chambers, et al. 2015. Simple psychological interventions for reducing pain from common needle procedures in adults: Systematic review of randomized and quasi-randomized controlled trials. The Clinical Journal of Pain 31(Suppl 10): S90.
   PubMedGoogle Scholar
• Bostick, N. A., R. Sade, M. A. Levine, and D. M. Stewart. 2008. Placebo use in clinical practice: Report of the american medical association council on ethical and judicial affairs. Journal of Clinical Ethics 19(1): 58–61.
   PubMedGoogle Scholar
• Carvalho, C.,. J. M. Caetano, L. Cunha, et al. 2016. Open-label placebo treatment in chronic low back pain: A randomized controlled trial. Pain 157(12): 2766–2772. doi:10.1097/j.pain.0000000000000700
   PubMed Web of Science ®Google Scholar
• Coghill, R. C., J. G. McHaffie, and Y. F. Yen. 2003. Neural correlates of interindividual differences in the subjective experience of pain. Proceedings of the National Academy of Sciences 100(14): 8538–8542. doi:10.1073/pnas.1430684100
   PubMed Web of Science ®Google Scholar
• Cohen, S. 2014. The nocebo effect of informed consent. Bioethics 28(3): 147–154.
   PubMed Web of Science ®Google Scholar
• Cohen, S., and H. Shapiro. 2013. “Comparable placebo treatment” and the ethics of deception. Journal of Medicine and Philosophy 38(6): 696–709.
   PubMed Web of Science ®Google Scholar
• de Craen, A. J. M., P. J. Roos, A. L. de Vries, and J. Kleijnen. 1996. Effect of colour of drugs: Systematic review of perceived effect of drugs and of their effectiveness. BMJ: British Medical Journal 313(7072): 1624–1626.
   Google Scholar
• Derbyshire, S. W., M. G. Whalley, V. A. Stenger, and D. A. Oakley. 2004. Cerebral activation during hypnotically induced and imagined pain. Neuroimage 23(1): 392–401. doi:10.1016/j.neuroimage.2004.04.033
   PubMed Web of Science ®Google Scholar
• Eccleston, C., G. Crombez, S. Aldrich, and C. Stannard. 1997. Attention and somatic awareness in chronic pain. Pain 72(1): 209–215. doi:10.1016/S0304-3959(97)00030-4
   PubMed Web of Science ®Google Scholar
• Eippert, F., J. Finsterbusch, U. Bingel, and C. Buchel. 2009. Direct evidence for spinal cord involvement in placebo analgesia. Science 326(5951): 404. doi:10.1126/science.1180142
   PubMed Web of Science ®Google Scholar
• Foddy, B. 2009. A duty to deceive: Placebos in clinical practice. The American Journal of Bioethics 9(12): 4–12. doi:10.1080/15265160903318350
   PubMed Web of Science ®Google Scholar
• Fortunato, J. T., J. A. Wasserman, and D. L. Menkes. 2017. When respecting autonomy is harmful: A clinically useful approach to the nocebo effect. The American Journal of Bioethics 17(6): 36–42. doi:10.1080/15265161.2017.1314042
   PubMed Web of Science ®Google Scholar
• Gligorov, N. 2016. Objectifying pain. In Neuroethics and the Scientific Revision of Common Sense, 117–137: Dordrecht, The Netherlands: Springer.
   Google Scholar
• Gligorov, N. 2017. Don’t worry, this will only hurt a bit: The role of expectation and attention in pain intensity. The Monist 100(4): 501–513.
   Web of Science ®Google Scholar
• Harkins, S. W., D. D. Price, and J. Braith. 1989. Effects of extraversion and neuroticism on experimental pain, clinical pain, and illness behavior. Pain 36(2): 209–218. doi:10.1016/0304-3959(89)90025-0
   PubMed Web of Science ®Google Scholar
• Hawker, G. A., S. Mian, T. Kendzerska, and M. French. 2011. Measures of adult pain: Visual analog scale for pain (VAS pain), numeric rating scale for pain (NRS pain), McGill pain questionnaire (MPQ), short-Form McGill pain questionnaire (SF-MPQ), chronic pain grade scale (CPGS), short form-36 bodily pain scale (SF-36 BPS), and measure of intermittent and constant osteoarthritis pain (ICOAP). Arthritis Care & Research 63(S11): S240–S252. doi:10.1002/acr.20543
   PubMed Web of Science ®Google Scholar
• International Association for the Study of Pain. 2017. IASP Taxonomy. Retrieved from https://www.iasp-pain.org/Taxonomy
   Google Scholar
• Kaptchuk, T. J., E. Friedlander, J. M. Kelley, et al. 2010. Placebos without deception: A randomized controlled trial in irritable bowel syndrome. PLOS One 5(12): e15591. doi:10.1371/journal.pone.0015591
   PubMed Web of Science ®Google Scholar
• Kessner, S., K. Wiech, K. Forkmann, M. Ploner, and U. Bingel. 2013. The effect of treatment history on therapeutic outcome: An experimental approach. JAMA Internal Medicine 173(15): 1468–1469. doi:10.1001/jamainternmed.2013.6705
   PubMed Web of Science ®Google Scholar
• Kong, J., R. Spaeth, A. Cook, et al. 2013. Are all placebo effects equal? placebo pills, sham acupuncture, cue conditioning and their association. PLOS One 8(7): e67485
   PubMed Web of Science ®Google Scholar
• Melzack, R., and K. L. Casey. 1968. Sensory, motivational and central control determinants of pain: A new conceptual model. In The skin senses. ed. D. R. Kenshalo, Vol. 1, 423–439. Springfield, IL: C.C.Thomas.
   Google Scholar
• Melzack, R., and P. D. Wall. 1965. Pain mechanisms - a new theory. Science 150(3699): 971–979. doi:10.1126/science.150.3699.971
   PubMed Web of Science ®Google Scholar
• Moayedi, M., and K. D. Davis. 2013. Theories of pain: From specificity to gate control. Journal of Neurophysiology 109(1): 5–12. doi:10.1152/jn.00457.2012
   PubMed Web of Science ®Google Scholar
• Moerman, D. E., and W. B. Jonas. 2002. Deconstructing the placebo effect and finding the meaning response. Annals of Internal Medicine 136(6): 471–476.
   PubMed Web of Science ®Google Scholar
• Petrovic, P., K. M. Petersson, P. H. Ghatan, S. Stone-Elander, and M. Ingvar. 2000. Pain-related cerebral activation is altered by a distracting cognitive task. Pain 85(1): 19–30. doi:10.1016/S0304-3959(99)00232-8
   PubMed Web of Science ®Google Scholar
• Ramirez-Maestre, C., R. Esteve, and A. E. Lopez. 2008. Cognitive appraisal and coping in chronic pain patients. European Journal of Pain 12(6): 749–756. doi:10.1016/j.ejpain.2007.11.004
   PubMed Web of Science ®Google Scholar
• Sandler, A. D., and J. W. Bodfish. 2007. Open-label use of placebos in the treatment of ADHD: A pilot study. Child: Care, Health and Development 34(1): 104–110. doi:10.1111/j.1365-22142007.00797.x
   Web of Science ®Google Scholar
• Tracey, I., A. Ploghaus, J. S. Gati, et al. 2002. Imaging attentional modulation of pain in the periaqueductal gray in humans. The Journal of Neuroscience 22(7): 2748–2752.
   PubMed Web of Science ®Google Scholar
• Tracey, I., and P. W. Mantyh. 2007. The cerebral signature and its modulation for pain perception. Neuron 55(3): 377–391. doi:10.1016/j.neuron.2007.07.012
   PubMed Web of Science ®Google Scholar
• Wells, R. E., and T. J. Kaptchuk. 2012. To tell the truth, the whole truth, may do patients harm: The problem of the nocebo effect for informed consent. American Journal of Bioethics 12(3): 22–29. doi:10.1080/15265161.2011.652798
   PubMed Web of Science ®Google Scholar
• Wiech, K., J. Vandekerckhove, J. Zaman, et al. 2014. Influence of prior information on pain involves biased perceptual decision-making. Current Biology 24(15): R679–R681. doi:10.1016/j.cub.2014.06.022
   PubMed Web of Science ®Google Scholar
• Wiech, K., M. Ploner, and I. Tracey. 2008. Neurocognitive aspects of pain perception. Trends in Cognitive Sciences 12(8): 306–313. doi:10.1016/j.tics.2008.05.005
   PubMed Web of Science ®Google Scholar