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Original Articles

Steps Toward Gene Therapy: 1. The Initial Trials

Pages 33-40 | Published online: 24 Jun 2015

Selected Reading

  • Anderson WF: Prospects for Human Gene Therapy. Science 226:401, 1984
  • Blaese RM: Development of gene therapy for immunodeficiency: Adenosine deaminase deficiency. Pediatr Res 33 (1 Suppl): S49, 1993
  • Culver K et al: Lymphocytes as cellular vehicles for gene therapy in mouse and man. Proc Natl Acad Sci(USA) 88:3155, 1991
  • Kantoff PW et al: Correction of adenosine deaminase deficiency in cultured human T and B cells by retrovirus-mediated gene transfer. Proc Natl Acad Sci(USA) 83:6563, 1986
  • Kohn DB et al: Gene therapy for neonates with ADA-deficient SCID by retroviral-mediated transfer of the human ADA cDNA into umbilical cord CD34+ cells. J Cell Biochem Suppl 18A: 238, 1994
  • Nienhuis AW, McDonagh KT, Bodine DM: Gene transfer Into hematopoietic stem cells. Cancer 67 (10 Suppl): 2700, 1991
  • Wijnaendts L et al: Development of immunologic functions after bone marrow transplantation In 33 patients with severe combined immunodeficiency. Blood 74:2212, 1989

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