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Primary Research

Crystal structure of porcine pancreatic phospholipase A2 in complex with 2-methoxycyclohexa-2-5-diene-1,4-dione

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Pages 135-139 | Received 22 Aug 2011, Accepted 20 Apr 2012, Published online: 06 Aug 2012

References

  • Anderson , K M , Roshak , A , Winkler , J D , McCord , M and Marshall , L A . 1997 . Cytosolic 85-kDa phospholipase A2-mediated release of arachidonic acid is critical for proliferation of vascular smooth muscle cells . J Biol Chem. 272:30504–30511. ,
  • Berg , O G , Gelb , M H , Tsai , M D and Jain , M K . 2001 . Interfacial enzymology: the secreted phospholipase A2-paradigm . Chem Rev. , 101 : 2613 – 2654 .
  • Brooks , B R , Bruccoleri , R E , Olafson , B D , States , D J , Swaminathan , S and Karplus , M . 1983 . CHARMM: a program for macromolecular energy minimization and dynamics calculations . J Comput Chem. , 4 : 187 – 217 .
  • Chainani-Wu , N . 2003 . Safety and anti-inflammatory activity of curcumin: a component of tumeric Curcuma longa . J Altern Complement Med. , 9 : 161 – 168 .
  • Chinthalapally , V R . 2007 . Regulation of cox and lox by curcumin: the molecular targets and therapeutic uses of curcumin in health and disease . Adv Exp Med Biol. , 595 : 213 – 226 .
  • Dileep , K V , Tintu , I and Sadasivan , C . 2011 . Molecular docking studies of curcumin analogs with phospholipase A2 . Interdiscip Sci. , 3 : 189 – 197 .
  • Dijkstra , B W , Renetseder , R , Kalk , K H , Hol , W G and Drenth , J . 1983 . Structure of porcine pancreatic phospholipase A2 at 2.6 A resolution and comparison with bovine phospholipase A2 . J Mol Biol. , 168 : 163 – 179 .
  • Emsley , P and Cowtan , K . 2004 . Coot: model-building tools for molecular graphics . Acta Crystallogr D. , 60 : 2126 – 2132 .
  • Ewa , S J , McCabe , P N , Steven , H S and Jankun , J . 2000 . Curcumin inhibits lipoxygenase by binding to its central cavity: theoretical and X-ray evidence . Int J Mol Med. , 6 : 521 – 526 .
  • Huang , M T , Newmark , H L and Frenkel , K . 1997 . Inhibitory effects of curcumin on tumorigenesis in mice . J Cell Biochem. , 27 : 26 – 34 .
  • Julie , A G , Glenn , M S , Richard , B , Richard , L , Ken , Y H , Ivan , A R and Kieran , F S . 1991 . Circulating phospholipase A2 activity associated with sepsis and septic shock is indistinguishable from that associated with rheumatoid arthritis . Inflammation. , 15 : 355 – 367 .
  • Kudo , I and Murakami , M . 2002 . Phospholipase A2 enzymes . Prostaglandins Other Lipid Mediat. , : 68 – 69:3–58 .
  • Leslie , AG W . 2006 . The integration of macromolecular diffraction data . Acta Crystallogr D. , 62:48–57
  • Menon , V and Sudheer , A R . 2007 . Antioxidant and anti-inflammatory properties of curcumin . Adv Exp Med Biol. 595:105–125. ,
  • Nirmal , N , Om Prabha , G and Velmurugan , D . 2008 . Modeling studies on phospholipase A2-inhibitor complexes . Indian J Biochem Biophys. , 45 : 256 – 262 .
  • Pruzanski , W , Vadas , P and Browning , J . 1993 . Secretory non-pancreatic group II phospholipase A2: role in physiologic and inflammatory processes . J Lipid Mediat. , 8 : 161 – 167 .
  • Srimal , R C and Dhawan , B N . 1973 . Pharamacology of diferuloyl methane: a non steroidal anti-inflammatory drug . J Pharm Pharmacol. , 25:447
  • Vagin , A and Teplyakov , A . 2000 . An approach to multi-copy search in molecular replacement . Acta Crystallogr D. , 56 : 1622 – 1624 .
  • Verheij , H M , Volwerk , J J , Jansen , EHJ M , Puyk , W C , Dijkstra , B W , Drenth , J and de Haas , G H . 1980 . Methylation of histidine-48 in pancreatic phospholipase A2. Role of histidine and calcium ion in the catalytic mechanism . Biochem. , 19 : 43 – 50 .

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