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REVIEW

Prenatal and Perinatal Anesthesia and the Long-Term Cognitive Sequelae: A Review

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REFERENCES

  • Anand , K. J. S. , & Soriano , S. G. ( 2004 ). Anesthetic agents and the immature brain: Are these toxic or therapeutic? , Anesthesiology , 101 , 527 – 530 .
  • Bartels , M. , Alhoff , R. R. , Boosma , D. I. ( 2009 ). Anesthesia and cognitive performance in children: No evidence for a causal relationship . Twin Research and Human Genetics , 12 ( 3 ), 246 – 253 .
  • Bellinger , D. C. , Jonas , R. A. , Rappaport , L. A. , Wypij , D. , Wernovsky , G. , Kuban , K. C. K. , … Newburger , J. W. ( 1995 ). Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass , The New England Journal of Medicine , 332 , 549 – 555 .
  • Bellinger , D. C. , Wypij , D. , du Plessis , A. J. , Rappaport , L. A. , Jonas , R. A. , Wernovsky , G. , & Newburger , J. W. ( 2003 ). Neurodevelopmental status at eight years in children with dextra-transposition of the great arteries: The Boston Circulatory Arrest Trial , The Journal of Thoracic and Cardiovascular Surgery , 126 , 1385 – 2003 .
  • Bellinger , D. C. , Wypij , D. , Kuban , K. C. K. , Rappaport , L. A. , Hickey , P. R. , Wernovsky , G. , … Newburger , J. W. ( 1999 ). Developmental and neurological status of children at 4 years of age after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass , Circulation , 100 , 526 – 532 .
  • Blair , V. W. , Hollenbeck , A. R. , Smith , R. F. , & Scanlon , J. W. ( 1984 ). Neonatal preference for visual patterns: Modification by prenatal anesthetic exposure? , Developmental & Medical Child Neurology , 26 , 476 – 483 .
  • Blakely , M. L. , Tyson , J. E. , Lally , K. P. , McDonald , S. , Stoll , B. J. , Stevenson , D. K. , … Higgins , R. D. ( 2006 ). Laparotomy versus peritoneal drainage for necrotizing enterocolitis or isolated intestinal perforation in extremely low birth weight infants: Outcomes through 18 months adjusted age , Pediatrics , 117 , 680 – 687 .
  • Brodsky , J. B. ( 1983 ). Anesthesia and surgery during early pregnancy and fetal outcome , Clinical Obstetrics and Gynecology , 26 , 449 – 457 .
  • Chacko , J. , Ford , W. D. , & Haslam , R. ( 1999 ). Growth and neurodevelopmental outcome in extremely-low-birth-weight infants after laparotomy , Pediatric Surgery International , 15 , 496 – 499 .
  • Dietrich , K. ( 2010 ). Environmental toxicants . In K. O. Yeates , M. D. Ris , H. G. Taylor , & B. F. Pennington (Eds.), Pediatric neuropsychology (pp. 211 – 264 ). New York , NY : Guilford Press .
  • Duncan , P. G. , Pope , W. D. B. , Cohen , M. , & Greer , N. ( 1986 ). The safety of anesthesia and surgery during pregnancy , Anesthesiology , 64 , 790 – 794 .
  • Eishima , K. ( 1992 ). The effects of obstetric conditions on neonatal behaviour in Japanese infants , Early Human Development , 28 , 253 – 263 .
  • Fanzago , E. ( 2003 ). Anesthesia for non-obstetric surgery in pregnant patients , Minerva Anestesiologica , 69 , 416 – 427 .
  • Flick , R. P. , Katusic , S. K. , Colligan , R. C. , Wilder , R. T. , Voigt , R. G. , Olson , M. D. , … Warner , D. O. ( 2011 ). Cognitive and behavioral outcomes after early exposure to anesthesia and surgery , Pediatrics , 128 , 1053 – 1061 .
  • Goodman , S. ( 2002 ). Anesthesia for non-obstetric surgery in the pregnant patient , Seminars in Perinatology , 26 , 136 – 145 .
  • Hintz , S. R. , Kendrick , D. E. , Stoll , B. J. , Vohr , B. R. , Fanaroff , A. A. , Donovan , E. F. , … Higgins , R. ( 2005 ). Neurodevelopmental and growth outcomes of extremely low birth weight infants after necrotizing enterocolitis , Pediatrics , 115 , 696 – 703 .
  • Hollenbeck , A. R. , Grout , L. A. , Smith , R. F. , & Scanlon , J. W. ( 1986 ). Neonates prenatally exposed to anesthetics: Four-year follow-up , Child Psychiatry & Human Development , 17 , 66 – 70 .
  • Hollmen , A. I. , Jouppila , R. , Koivisto , M. , Maatta , L. , Pihlajaniemi , R. , Puukka , M. , & Rantakyla , P. ( 1978 ). Neurologic activity of infants following anesthesia for cesarean section , Anesthesiology , 48 , 350 – 356 .
  • Ikonomidou , C. , Bosch , F. , Miksa , M. , Bittigau , P. , Vockler , J. , Dikranian , K. , … Olney , J. W. (1999). Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain, Science , 283, 70–74.
  • Jevtovic-Todorovic , V. , Beals , J. , Benshoff , N. , & Olney , J. W. ( 2003 ). Prolonged exposure to inhalational anesthetic nitrous oxide kills neurons in adult rat brain , Neuroscience , 122 , 609 – 616 .
  • Jevtovic-Todorovic , V. , Hartman , R. E. , Izumi , Y. , Benshoff , N. D. , Dikranian , K. , Zorumski , C. F. , … Wozniak , D. F. ( 2003 ). Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits , Journal of Neuroscience , 23 , 876 – 882 .
  • Kabra , N. S. , Schmidt , B. , Roberts , R. S. , Doyle , L. W. , Papile , L. , & Fanaroff , A. ( 2007 ). Neurosensory impairment after surgical closure of patent ductus arteriosus in extremely low birth weight infants: Results from the Trial of Indomethacin Prophylaxis in Preterms , Journal of Pediatrics , 150 , 229 – 234 .
  • Kallen , B. , & Mazze , R. I. ( 1990 ). Neural tube defects and first trimester operations , Teratology , 41 , 717 – 720 .
  • Kuczkowski , K. M. ( 2004 ). Nonobstetric surgery during pregnancy: What are the risks of anesthesia? Obstetrical & Gynecological Survey , 59 , 52 – 56 . http://journals.lww.com/obgynsurvey/Abstract/2004/01000/Nonobstetric_Surgery_During_Pregnancy__What_Are.26.aspx
  • Lindahl , H. ( 1984 ). Long-term prognosis of successfully operated oesophageal atresia-with aspects on physical and psychological development . Zeitschrift für Kinderchirurgie (Surgery in Infancy and Childhood) , 39 , 6 – 10 .
  • Loepke , A. W. , & Soriano , S. G. ( 2008 ). An assessment of the effects of general anesthetics on developing brain structure and neurocognitive function , Anesthesia & Analgesia , 106 , 1681 – 1707 .
  • Mellon , R. D. , Simone , A. F. , & Rappaport , B. A. ( 2007 ). Use of anesthetic agents in neonates and young children , Anesthesia & Analgesia , 104 , 509 – 520 .
  • Middaugh , L. D. , Dow-Edwards , D. , Li , A. A. , Sandler , J. D. , Seed , J. , Sheets , L. P. , … Selwyn , M. R. ( 2003 ). Neurobehavioral assessment, a survey of use and value in safety assessment studies , Toxicology Science , 76 , 250 – 261 .
  • Olney , J. W. , Wozniak , D. F. , Jevtovic-Todorovic , V. , Farber , N. B. , Bittigau , P. , & Ikonomidou , C. ( 2002 ). Drug-induced apoptotic neurodegeneration in the developing brain , Brain Pathology , 12 , 488 – 498 .
  • Olney , J. W. , Young , C. , Wozniak , D. F. , Ikonomidou , C. , & Jevtovic-Todorovic , V. ( 2004 ). Anesthesia-induced development neuroapoptosis. Does it happen in humans? , Anesthesiology , 101 , 273 – 275 .
  • Olney , J. W. , Young , C. , Wozniak , D. F. , Jevtovic-Todorovic , V. , & Ikonomidou , C. ( 2004 ). Do pediatric drugs cause developing neurons to commit suicide? , Trends in Pharmacology Science , 25 , 135 – 139 .
  • Paule , M. G. , Li , M. , Allen , R. R. , Liu , F. , Zou , X. , Hotchkiss , C. , … Wang , C. ( 2011 ). Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys , Neurotoxicology and Teratology , 33 , 220 – 230 .
  • Rice , D. , & Barone , S. , Jr. ( 2000 ). Critical periods of venerability for the developing nervous system: Evidence from humans and animal models . Environmental Health Perspective , 108 ( Suppl. 3 ), 511 – 533 .
  • Rizzi , S. , Carter , L. B. , Ori , C. , & Jevtovic-Todorovic , V. ( 2008 ). Clinical anesthesia causes permanent damage to the fetal guinea pig brain . Brain Pathology , 18 ( 2 ), 198 – 210 .
  • Rosen , M. A. ( 1999 ). Management of anesthesia for the pregnant patient , Anesthesiology , 91 , 1159 – 1163 .
  • Satomoto , M. , Satoh , Y. , Terui , K. , Miyao , H. , Takishima , K. , Ito , M. , & Imaki , J. ( 2009 ). Neonatal exposure to sevoflurane induces abnormal social behaviors and deficits in fear conditioning in mice , Anesthesiology , 110 , 628 – 637 .
  • Scallet , A. C. , Kowalke , P. K. , Roundtree , R. L. , Thorn , B. T. , & Binienda , Z. K. ( 2004 ). Electroencephalographic, behavioral, and c-fos responses to acute domoic acid exposure , Neurotoxical Teratology , 26 , 331 – 342 .
  • Simon , N. P. , Brady , N. R. , Stafford , R. L. , & Powell , R. W. ( 1993 ). The effect of abdominal incisions on early motor development of infants with necrotizing enterocolitis , Developmental and Medical Child Neurology , 35 , 49 – 53 .
  • Slikker , W. , Jr., Zou , X. , Hotchkiss , C. E. , Divine , R. L. , Sadvova , N. , Twaddle , N. C. , … Hanig , J. P. ( 2007 ). Developmental neurotoxicity of ketamine: Morphometric confirmation, exposure parameters, and multiple fluorescent labeling of apoptotic neurons , Toxicological Sciences , 81 , 364 – 370 .
  • Sylvester , K. G. , Khoury , M. J. , Lu , X. , & Erickson , J. D. ( 1994 ). First trimester anesthesia and the risk of central nervous system defects: A population based case control study , American Journal of Public Health , 84 , 1757 – 1760 .
  • Tobiansky , R. , Lui , K. , Roberts , S. , & Veddovi , M. ( 1995 ). Neurodevelopmental outcome in very low birthweight infants with necrotizing enterocolitis requiring surgery , Journal of Paediatric Child Health , 31 , 233 – 236 .
  • Uemura , E. , & Bowman , R. E. ( 1980 ). Effects of halothane on cerebral synaptic density . Experimental Neurology , 69 , 135 – 142 . http://www.sciencedirect.com/science/article/pii/0014488680901491
  • Wang , C. , Sadovova , N. , Fu , X. , Schmued , L. , Scallet , A. , Hanig , J. , & Slikker , W. ( 2005 ). The role of the N-methyl-D-aspartate receptor in ketamine-induced apoptosis in rat forebrain culture , Neuroscience , 132 , 967 – 977 .
  • Wilder , R. T. , Flick , R. P. , Prung , J. , Katusic , S. K. , Barbaresi , W. J. , Michelson , C. , … Warner , D. O. ( 2009 ). Early exposure to anesthesia and learning disabilities in a population-based birth cohort , Anesthesiology , 110 , 796 – 804 .
  • Yon , J. H. , Daniel-Johnson , J. , Carter , L. B. , & Jevtovic-Todorovic , V. ( 2005 ). Anesthesia induces neuronal cell death in the developing rat brain via the intrinsic and extrinsic apoptotic pathways , Neuroscience , 135 , 815 – 827 .

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