Obesity-induced remodeling of the adipose tissue elastin network is independent of the metalloelastase MMP-12

References

• Divoux A, Tordjman J, Lacasa D, Veyrie N, Hugol D, Aissat A, Basdevant A, Guerre-Millo M, Poitou C, Zucker JD, et al. Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass loss. Diabetes 2010; 59:2817-25; PMID:20713683; http://dx.doi.org/10.2337/db10-0585
   PubMed Web of Science ®Google Scholar
• Chun TH. Peri-adipocyte ECM remodeling in obesity and adipose tissue fibrosis. Adipocyte 2012; 1:89-95; PMID:23700517; http://dx.doi.org/10.4161/adip.19752
   PubMedGoogle Scholar
• Chun TH, Hotary KB, Sabeh F, Saltiel AR, Allen ED, Weiss SJ. A pericellular collagenase directs the 3-dimensional development of white adipose tissue. Cell 2006; 125:577-91; PMID:16678100; http://dx.doi.org/10.1016/j.cell.2006.02.050
   PubMed Web of Science ®Google Scholar
• Sun K, Tordjman J, Clement K, Scherer PE. Fibrosis and adipose tissue dysfunction. Cell Metab 2013; 18:470-7; PMID:23954640; http://dx.doi.org/10.1016/j.cmet.2013.06.016
   PubMed Web of Science ®Google Scholar
• Kielty CM, Sherratt MJ, Shuttleworth CA. Elastic fibres. J Cell Sci 2002; 115:2817-28; PMID:12082143
   PubMed Web of Science ®Google Scholar
• Holst J, Watson S, Lord MS, Eamegdool SS, Bax DV, Nivison-Smith LB, Kondyurin A, Ma L, Oberhauser AF, Weiss AS, et al. Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells. Nat Biotechnol 2010; 28:1123-8; PMID:20890282; http://dx.doi.org/10.1038/nbt.1687
   PubMed Web of Science ®Google Scholar
• Spencer M, Unal R, Zhu B, Rasouli N, McGehee RE Jr, Peterson CA, Kern PA. Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance. J Clin Endocrinol Metab 2011; 96:E1990-8; PMID:21994960; http://dx.doi.org/10.1210/jc.2011-1567
   PubMed Web of Science ®Google Scholar
• Khan T, Muise ES, Iyengar P, Wang ZV, Chandalia M, Abate N, Zhang BB, Bonaldo P, Chua S, Scherer PE. Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI. Mol Cell Biol 2009; 29:1575-91; PMID:19114551; http://dx.doi.org/10.1128/MCB.01300-08
   PubMed Web of Science ®Google Scholar
• Maki JM, Sormunen R, Lippo S, Kaarteenaho-Wiik R, Soininen R, Myllyharju J. Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues. Am J Pathol 2005; 167:927-36; PMID:16192629; http://dx.doi.org/10.1016/S0002-9440(10)61183-2
   PubMed Web of Science ®Google Scholar
• Halberg N, Khan T, Trujillo ME, Wernstedt-Asterholm I, Attie AD, Sherwani S, Wang ZV, Landskroner-Eiger S, Dineen S, Magalang UJ, et al. Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue. Mol Cell Biol 2009; 29:4467-83; PMID:19546236; http://dx.doi.org/10.1128/MCB.00192-09
   PubMed Web of Science ®Google Scholar
• Blaise S, Romier B, Kawecki C, Ghirardi M, Rabenoelina F, Baud S, Duca L, Maurice P, Heinz A, Schmelzer CE, et al. Elastin-derived peptides, new regulators of insulin resistance development in mice. Diabetes 2013; PMID:23919962
   PubMedGoogle Scholar
• Lijnen HR, Maquoi E, Hansen LB, Van Hoef B, Frederix L, Collen D. Matrix metalloproteinase inhibition impairs adipose tissue development in mice. Atertio Thromb Vasc Biol 2002; 22:374-9; http://dx.doi.org/10.1161/hq0302.104522
   PubMed Web of Science ®Google Scholar
• Maquoi E, Munaut C, Colige A, Collen D, Lijnen HR. Modulation of adipose tissue expression of murine matrix metalloproteinases and their tissue inhibitors with obesity. Diabetes 2002; 51:1093-101; PMID:11916931; http://dx.doi.org/10.2337/diabetes.51.4.1093
   PubMed Web of Science ®Google Scholar
• Chavey C, Mari B, Monthouel MN, Bonnafous S, Anglard P, Van Obberghen E, Tartare-Deckert S. Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation. J Biol Chem 2003; 278:11888-96; PMID:12529376; http://dx.doi.org/10.1074/jbc.M209196200
   PubMed Web of Science ®Google Scholar
• Werb Z, Gordon S. Elastase secretion by stimulated macrophages. Characterization and regulation. J Exp Med 1975; 142:361-77; PMID:167096; http://dx.doi.org/10.1084/jem.142.2.361
   PubMed Web of Science ®Google Scholar
• Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 1997; 277:2002-4; PMID:9302297; http://dx.doi.org/10.1126/science.277.5334.2002
   PubMed Web of Science ®Google Scholar
• Hunninghake GM, Cho MH, Tesfaigzi Y, Soto-Quiros ME, Avila L, Lasky-Su J, Stidley C, Melen E, Soderhall C, Hallberg J, et al. MMP12, lung function, and COPD in high-risk populations. N Engl J Med 2009; 361:2599-608; PMID:20018959; http://dx.doi.org/10.1056/NEJMoa0904006
   PubMed Web of Science ®Google Scholar
• Shaul ME, Bennett G, Strissel KJ, Greenberg AS, Obin MS. Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet–induced obesity in mice. Diabetes 2010; 59:1171-81; PMID:20185806; http://dx.doi.org/10.2337/db09-1402
   PubMed Web of Science ®Google Scholar
• Huber J, Loffler M, Bilban M, Reimers M, Kadl A, Todoric J, Zeyda M, Geyeregger R, Schreiner M, Weichhart T, et al. Prevention of high-fat diet-induced adipose tissue remodeling in obese diabetic mice by n-3 polyunsaturated fatty acids. Int J Obes (Lond) 2007; 31:1004-13; PMID:17130847; http://dx.doi.org/10.1038/sj.ijo.0803511
   PubMed Web of Science ®Google Scholar
• Bauters D, Van Hul M, Lijnen HR. Macrophage elastase (MMP-12) in expanding murine adipose tissue. Biochim Biophys Acta 2013; 1830:2954-9; PMID:23295969; http://dx.doi.org/10.1016/j.bbagen.2012.12.024
   PubMed Web of Science ®Google Scholar
• Anyanwu AC, Bentley JK, Popova AP, Malas O, Alghanem H, Goldsmith AM, Hershenson MB, Pinsky DJ. Suppression of inflammatory cell trafficking and alveolar simplification by the heme oxygenase-1 product carbon monoxide. Am J Physiol Lung Cell Mol Physiol 2014; 306:L749-63; PMID:24532288; http://dx.doi.org/10.1152/ajplung.00236.2013
   PubMedGoogle Scholar
• Lumeng CN, Liu J, Geletka L, Delaney C, Delproposto J, Desai A, Oatmen K, Martinez-Santibanez G, Julius A, Garg S, et al. Aging is associated with an increase in T cells and inflammatory macrophages in visceral adipose tissue. J Immunol 2011; 187:6208-16; PMID:22075699; http://dx.doi.org/10.4049/jimmunol.1102188
   PubMedGoogle Scholar
• Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007; 117:175-84; PMID:17200717; http://dx.doi.org/10.1172/JCI29881
   PubMed Web of Science ®Google Scholar
• Kosteli A, Sugaru E, Haemmerle G, Martin JF, Lei J, Zechner R, Ferrante AW Jr. Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue. J Clin Invest 2010; 120:3466-79; PMID:20877011; http://dx.doi.org/10.1172/JCI42845
   PubMed Web of Science ®Google Scholar
• Alkhouli N, Mansfield J, Green E, Bell J, Knight B, Liversedge N, Tham JC, Welbourn R, Shore AC, Kos K, et al. The mechanical properties of human adipose tissues and their relationships to the structure and composition of the extracellular matrix. Am J Physiol Endocrinol Metab 2013; 305:E1427-35; PMID:24105412; http://dx.doi.org/10.1152/ajpendo.00111.2013
   PubMed Web of Science ®Google Scholar
• Blaauboer ME, Boeijen FR, Emson CL, Turner SM, Zandieh-Doulabi B, Hanemaaijer R, Smit TH, Stoop R, Everts V. Extracellular matrix proteins: a positive feedback loop in lung fibrosis? Matrix Biol 2014; 34:170-8; PMID:24291458; http://dx.doi.org/10.1016/j.matbio.2013.11.002
   PubMed Web of Science ®Google Scholar
• Wagenseil JE, Mecham RP. Elastin in large artery stiffness and hypertension. J Cardiovasc Transl Res 2012; 5:264-73; PMID:22290157; http://dx.doi.org/10.1007/s12265-012-9349-8
   PubMed Web of Science ®Google Scholar
• Kamisato S, Uemura Y, Takami N, Okamoto K. Involvement of intracellular cyclic GMP and cyclic GMP-dependent protein kinase in alpha-elastin-induced macrophage chemotaxis. J Biochem 1997; 121:862-7; PMID:9192726; http://dx.doi.org/10.1093/oxfordjournals.jbchem.a021666
   PubMedGoogle Scholar
• Hunninghake GW, Davidson JM, Rennard S, Szapiel S, Gadek JE, Crystal RG. Elastin fragments attract macrophage precursors to diseased sites in pulmonary emphysema. Science 1981; 212:925-7; PMID:7233186; http://dx.doi.org/10.1126/science.7233186
   PubMed Web of Science ®Google Scholar
• Lee JT, Pamir N, Liu NC, Kirk EA, Averill MM, Becker L, Larson I, Hagman DK, Foster-Schubert KE, van Yserloo B, et al. Macrophage metalloelastase (MMP12) regulates adipose tissue expansion, insulin sensitivity, and expression of inducible nitric oxide synthase. Endocrinology 2014; 155:3409-20; PMID:24914938; http://dx.doi.org/10.1210/en.2014-1037
   PubMed Web of Science ®Google Scholar
• Talukdar S, Oh da Y, Bandyopadhyay G, Li D, Xu J, McNelis J, Lu M, Li P, Yan Q, Zhu Y, et al. Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. Nat Med 2012; 18:1407-12; PMID:22863787; http://dx.doi.org/10.1038/nm.2885
   PubMed Web of Science ®Google Scholar
• Yang M, Sun J, Zhang T, Liu J, Zhang J, Shi MA, Darakhshan F, Guerre-Millo M, Clement K, Gelb BD, et al. Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice. Arterioscler Thromb Vac Biol 2008; 28:2202-8; http://dx.doi.org/10.1161/ATVBAHA.108.172320
   PubMed Web of Science ®Google Scholar
• Lumeng CN, DelProposto JB, Westcott DJ, Saltiel AR. Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes. Diabetes 2008; 57:3239-46; PMID:18829989; http://dx.doi.org/10.2337/db08-0872
   PubMed Web of Science ®Google Scholar
• Knudsen L, Weibel ER, Gundersen HJ, Weinstein FV, Ochs M. Assessment of air space size characteristics by intercept (chord) measurement: an accurate and efficient stereological approach. J Appl Physiol (1985) 2010; 108:412-21; PMID:19959763; http://dx.doi.org/10.1152/japplphysiol.01100.2009
   PubMed Web of Science ®Google Scholar
• Morris DL, Oatmen KE, Wang T, DelProposto JL, Lumeng CN. CX3CR1 deficiency does not influence trafficking of adipose tissue macrophages in mice with diet-induced obesity. Obesity 2012; 20:1189-99; PMID:22252034; http://dx.doi.org/10.1038/oby.2012.7
   PubMedGoogle Scholar
• Morris DL, Cho KW, Delproposto JL, Oatmen KE, Geletka LM, Martinez-Santibanez G, Singer K, Lumeng CN. Adipose tissue macrophages function as antigen presenting cells and regulate adipose tissue CD4+ T cells in mice. Diabetes 2013; 62:2762-72; PMID:23493569; http://dx.doi.org/10.2337/db12-1404
   PubMedGoogle Scholar