1,597
Views
14
CrossRef citations to date
0
Altmetric
Commentaries

Molecular clock integration of brown adipose tissue formation and function

, &
Pages 243-250 | Received 07 Jul 2015, Accepted 06 Aug 2015, Published online: 21 Feb 2016

References

  • Dibner C, Schibler U, Albrecht U. The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annu Rev Physiol 2010; 72:517-49; PMID:20148687; http://dx.doi.org/10.1146/annurev-physiol-021909-135821
  • Reppert SM, Weaver DR. Coordination of circadian timing in mammals. Nature 2002; 418:935-41; PMID:12198538; http://dx.doi.org/10.1038/nature00965
  • Schibler U, Sassone-Corsi P. A web of circadian pacemakers. Cell 2002; 111:919-22; PMID:12507418; http://dx.doi.org/10.1016/S0092-8674(02)01225-4
  • Rey G, Cesbron F, Rougemont J, Reinke H, Brunner M, Naef F. Genome-Wide and Phase-Specific DNA-Binding Rhythms of BMAL1 Control Circadian Output Functions in Mouse Liver. PLoS Biol 2011; 9:e1000595; PMID:21364973; http://dx.doi.org/10.1371/journal.pbio.1000595
  • Stratmann M, Schibler U. REV-ERBs: more than the sum of the individual parts. Cell Metab 2012; 15:791-3; PMID:22682217; http://dx.doi.org/10.1016/j.cmet.2012.05.006
  • Preitner N, Damiola F, Lopez-Molina L, Zakany J, Duboule D, Albrecht U, Schibler U. The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator. Cell 2002; 110:251-60; PMID:12150932; http://dx.doi.org/10.1016/S0092-8674(02)00825-5
  • Cannon B, Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol Rev 2004; 84:277-359; PMID:14715917; http://dx.doi.org/10.1152/physrev.00015.2003
  • Yoneshiro T, Aita S, Matsushita M, Kayahara T, Kameya T, Kawai Y, Iwanaga T, Saito M. Recruited brown adipose tissue as an antiobesity agent in humans. J Clin Invest 2013; 123:3404-8; PMID:23867622; http://dx.doi.org/10.1172/JCI67803
  • Stanford KI, Middelbeek RJ, Townsend KL, An D, Nygaard EB, Hitchcox KM, Markan KR, Nakano K, Hirshman MF, Tseng YH, et al. Brown adipose tissue regulates glucose homeostasis and insulin sensitivity. J Clin Invest 2013; 123:215-23; PMID:23221344; http://dx.doi.org/10.1172/JCI62308
  • Bartelt A, Bruns OT, Reimer R, Hohenberg H, Ittrich H, Peldschus K, Kaul MG, Tromsdorf UI, Weller H, Waurisch C, et al. Brown adipose tissue activity controls triglyceride clearance. Nat Med 2011; 17:200-5; PMID:21258337; http://dx.doi.org/10.1038/nm.2297
  • Bass J, Takahashi JS. Circadian integration of metabolism and energetics. Science 2010; 330:1349-54; PMID:21127246; http://dx.doi.org/10.1126/science.1195027
  • Panda S, Antoch MP, Miller BH, Su AI, Schook AB, Straume M, Schultz PG, Kay SA, Takahashi JS, Hogenesch JB. Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 2002; 109:307-20; PMID:12015981; http://dx.doi.org/10.1016/S0092-8674(02)00722-5
  • Eckel-Mahan KL, Patel VR, Mohney RP, Vignola KS, Baldi P, Sassone-Corsi P. Coordination of the transcriptome and metabolome by the circadian clock. Proc Natl Acad Sci U S A 2012; 109:5541-6; PMID:22431615; http://dx.doi.org/10.1073/pnas.1118726109
  • Turek FW, Joshu C, Kohsaka A, Lin E, Ivanova G, McDearmon E, Laposky A, Losee-Olson S, Easton A, Jensen DR, et al. Obesity and metabolic syndrome in circadian Clock mutant mice. Science 2005; 308:1043-5; PMID:15845877; http://dx.doi.org/10.1126/science.1108750
  • Karatsoreos IN, Bhagat S, Bloss EB, Morrison JH, McEwen BS. Disruption of circadian clocks has ramifications for metabolism, brain, and behavior. Proc Natl Acad Sci U S A 2011; 108:1657-62; PMID:21220317; http://dx.doi.org/10.1073/pnas.1018375108
  • Grimaldi B, Bellet MM, Katada S, Astarita G, Hirayama J, Amin RH, Granneman JG, Piomelli D, Leff T, Sassone-Corsi P. PER2 controls lipid metabolism by direct regulation of PPARgamma. Cell Metab 2010; 12:509-20; PMID:21035761; http://dx.doi.org/10.1016/j.cmet.2010.10.005
  • Pan A, Schernhammer ES, Sun Q, Hu FB. Rotating night shift work and risk of type 2 diabetes: two prospective cohort studies in women. PLoS Med 2011; 8:e1001141; PMID:22162955; http://dx.doi.org/10.1371/journal.pmed.1001141
  • Parkes KR. Shift work and age as interactive predictors of body mass index among offshore workers. Scand J Work Environ Health 2002; 28:64-71; PMID:11871855; http://dx.doi.org/10.5271/sjweh.648
  • Scheer FA, Hilton MF, Mantzoros CS, Shea SA. Adverse metabolic and cardiovascular consequences of circadian misalignment. Proc Natl Acad Sci U S A 2009; 106:4453-8; PMID:19255424; http://dx.doi.org/10.1073/pnas.0808180106
  • Lamia KA, Storch KF, Weitz CJ. Physiological significance of a peripheral tissue circadian clock. Proc Natl Acad Sci U S A 2008; 105:15172-7; PMID:18779586; http://dx.doi.org/10.1073/pnas.0806717105
  • Guo B, Chatterjee S, Li L, Kim JM, Lee J, Yechoor VK, Minze LJ, Hsueh W, Ma K. The clock gene, brain and muscle Arnt-like 1, regulates adipogenesis via Wnt signaling pathway. FASEB J 2012; 26:3453-63; PMID:22611086; http://dx.doi.org/10.1096/fj.12-205781
  • Lee J, Kim MS, Li R, Liu VY, Fu L, Moore DD, Ma K, Yechoor VK. Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in β-cells. Islets 2011; 3:381-8; PMID:22045262; http://dx.doi.org/10.4161/isl.3.6.18157
  • Goumidi L, Grechez A, Dumont J, Cottel D, Kafatos A, Moreno LA, Molnar D, Moschonis G, Gottrand F, Huybrechts I, et al. Impact of REV-ERB α gene polymorphisms on obesity phenotypes in adult and adolescent samples. Int J Obes (Lond) 2014; 37:666-72; http://dx.doi.org/10.1038/ijo.2012.117
  • Fontaine C, Dubois G, Duguay Y, Helledie T, Vu-Dac N, Gervois P, Soncin F, Mandrup S, Fruchart JC, Fruchart-Najib J, et al. The orphan nuclear receptor Rev-Erbalpha is a peroxisome proliferator-activated receptor (PPAR) gamma target gene and promotes PPARgamma-induced adipocyte differentiation. J Biol Chem 2003; 278:37672-80; PMID:12821652; http://dx.doi.org/10.1074/jbc.M304664200
  • Roenneberg T, Allebrandt KV, Merrow M, Vetter C. Social jetlag and obesity. Curr Biol 2012; 22:939-43; PMID:22578422; http://dx.doi.org/10.1016/j.cub.2012.03.038
  • Coomans CP, van den Berg SA, Houben T, van Klinken JB, van den Berg R, Pronk AC, Havekes LM, Romijn JA, van Dijk KW, Biermasz NR, et al. Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity. FASEB J 2013; 27:1721-32; PMID:23303208; http://dx.doi.org/10.1096/fj.12-210898
  • Fonken LK, Aubrecht TG, Melendez-Fernandez OH, Weil ZM, Nelson RJ. Dim light at night disrupts molecular circadian rhythms and increases body weight. J Biol Rhythms 2013; 28:262-71; PMID:23929553; http://dx.doi.org/10.1177/0748730413493862
  • Kooijman S, van den Berg R, Ramkisoensing A, Boon MR, Kuipers EN, Loef M, Zonneveld TC, Lucassen EA, Sips HC, Chatzispyrou IA, et al. Prolonged daily light exposure increases body fat mass through attenuation of brown adipose tissue activity. Proc Natl Acad Sci U S A 2015; 112: 6748-53; PMID:25964318; http://dx.doi.org/10.1073/pnas.1504239112.
  • Herrero L, Valcarcel L, da Silva CA, Albert N, Diez-Noguera A, Cambras T, Serra D. Altered circadian rhythm and metabolic gene profile in rats subjected to advanced light phase shifts. PLoS One 2015; 10:e0122570; PMID:25837425; http://dx.doi.org/10.1371/journal.pone.0122570
  • Millar AJ. Input signals to the plant circadian clock. J Exp Bot 2004; 55:277-83; PMID:14695902; http://dx.doi.org/10.1093/jxb/erh034
  • Buhr ED, Yoo SH, Takahashi JS. Temperature as a universal resetting cue for mammalian circadian oscillators. Science 2010; 330:379-85; PMID:20947768; http://dx.doi.org/10.1126/science.1195262
  • Romanovsky AA. Thermoregulation: some concepts have changed. Functional architecture of the thermoregulatory system. Am J Physiol Regul Integr Comp Physiol 2007; 292:R37-46; PMID:17008453; http://dx.doi.org/10.1152/ajpregu.00668.2006
  • Refinetti R. The circadian rhythm of body temperature. Front Biosci (Landmark Ed) 2010; 15:564-94; PMID:20036834; http://dx.doi.org/10.2741/3634
  • van der Veen DR, Shao J, Chapman S, Leevy WM, Duffield GE. A Diurnal Rhythm in Glucose Uptake in Brown Adipose Tissue Revealed by In Vivo PET-FDG Imaging. Obesity (Silver Spring) 2012; 20:1527-9; PMID:22447290
  • Bartness TJ, Song CK, Demas GE. SCN efferents to peripheral tissues: implications for biological rhythms. J Biol Rhythms 2001; 16:196-204; PMID:11407779; http://dx.doi.org/10.1177/074873040101600302
  • Amir S. Retinohypothalamic tract stimulation activates thermogenesis in brown adipose tissue in the rat. Brain Res 1989; 503:163-6; PMID:2611651; http://dx.doi.org/10.1016/0006-8993(89)91720-4
  • Zvonic S, Ptitsyn AA, Conrad SA, Scott LK, Floyd ZE, Kilroy G, Wu X, Goh BC, Mynatt RL, Gimble JM. Characterization of peripheral circadian clocks in adipose tissues. Diabetes 2006; 55:962-70; PMID:16567517; http://dx.doi.org/10.2337/diabetes.55.04.06.db05-0873
  • Li S, Yu Q, Wang GX, Lin JD. The biological clock is regulated by adrenergic signaling in brown fat but is dispensable for cold-induced thermogenesis. PLoS One 2013; 8:e70109; PMID:23990898; http://dx.doi.org/10.1371/journal.pone.0070109
  • Chappuis S, Ripperger JA, Schnell A, Rando G, Jud C, Wahli W, Albrecht U. Role of the circadian clock gene Per2 in adaptation to cold temperature. Mol Metab 2013; 2:184-93; PMID:24049733; http://dx.doi.org/10.1016/j.molmet.2013.05.002
  • Vesala L, Salminen TS, Kankare M, Hoikkala A. Photoperiodic regulation of cold tolerance and expression levels of regucalcin gene in Drosophila montana. J Insect Physiol 2012; 58:704-9; PMID:22360999; http://dx.doi.org/10.1016/j.jinsphys.2012.02.004
  • Demas GE, Bowers RR, Bartness TJ, Gettys TW. Photoperiodic regulation of gene expression in brown and white adipose tissue of Siberian hamsters (Phodopus sungorus). Am J Physiol Regul Integr Comp Physiol 2002; 282:R114-121; PMID:11742829
  • Au-Yong IT, Thorn N, Ganatra R, Perkins AC, Symonds ME. Brown adipose tissue and seasonal variation in humans. Diabetes 2009; 58:2583-7; PMID:19696186; http://dx.doi.org/10.2337/db09-0833
  • Gerhart-Hines Z, Feng D, Emmett MJ, Everett LJ, Loro E, Briggs ER, Bugge A, Hou C, Ferrara C, Seale P, et al. The nuclear receptor Rev-erbalpha controls circadian thermogenic plasticity. Nature 2013; 503:410-3; PMID:24162845; http://dx.doi.org/10.1038/nature12642
  • Nam D, Guo B, Chatterjee S, Chen MH, Nelson D, Yechoor VK, Ma K. The adipocyte clock controls brown adipogenesis through the TGF-β and BMP signaling pathways. J Cell Sci 2015; 128:1835-47; PMID:25749863; http://dx.doi.org/10.1242/jcs.167643
  • Nam D, Chatterjee S, Yin H, Liu R, Lee J, Yechoor VK, Ma K. Novel Function of Rev-erbalpha in Promoting Brown Adipogenesis. Sci Rep 2015; 5:11239; PMID:26058812; http://dx.doi.org/10.1038/srep11239
  • Wang GX, Zhao XY, Lin JD. The brown fat secretome: metabolic functions beyond thermogenesis. Trends Endocrinol Metab 2015; 26:231-7; PMID:25843910; http://dx.doi.org/10.1016/j.tem.2015.03.002
  • Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, Ivanova G, Omura C, Mo S, Vitaterna MH, et al. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature 2010; 466:627-31; PMID:20562852; http://dx.doi.org/10.1038/nature09253
  • Chatterjee S, Nam D, Guo B, Kim JM, Winnier GE, Lee J, Berdeaux R, Yechoor VK, Ma K. Brain and muscle Arnt-like 1 is a key regulator of myogenesis. J Cell Sci 2013; 126:2213-24; PMID:23525013; http://dx.doi.org/10.1242/jcs.120519
  • Koncarevic A, Kajimura S, Cornwall-Brady M, Andreucci A, Pullen A, Sako D, Kumar R, Grinberg AV, Liharska K, Ucran JA, et al. A novel therapeutic approach to treating obesity through modulation of TGFbeta signaling. Endocrinology 2012; 153:3133-46; PMID:22549226; http://dx.doi.org/10.1210/en.2012-1016
  • Yadav H, Quijano C, Kamaraju AK, Gavrilova O, Malek R, Chen W, Zerfas P, Zhigang D, Wright EC, Stuelten C, et al. Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling. Cell Metab 2011; 14:67-79; PMID:21723505; http://dx.doi.org/10.1016/j.cmet.2011.04.013
  • Janich P, Pascual G, Merlos-Suarez A, Batlle E, Ripperger J, Albrecht U, Obrietan K, Di Croce L, Benitah SA. The circadian molecular clock creates epidermal stem cell heterogeneity. Nature 2011; 480: 209-14.
  • Chatterjee S, Yin H, Nam D, Li Y, Ma K. Brain and muscle Arnt-like 1 promotes skeletal muscle regeneration through satellite cell expansion. Exp Cell Res 2015; 331:200-10; PMID:25218946; http://dx.doi.org/10.1016/j.yexcr.2014.08.041
  • Karpowicz P, Zhang Y, Hogenesch JB, Emery P, Perrimon N. The circadian clock gates the intestinal stem cell regenerative state. Cell Rep 2013; 3:996-1004; PMID:23583176; http://dx.doi.org/10.1016/j.celrep.2013.03.016
  • Plikus MV, Vollmers C, de la Cruz D, Chaix A, Ramos R, Panda S, Chuong CM. Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling. Proc Natl Acad Sci U S A 2013; 110:E2106-15; PMID:23690597; http://dx.doi.org/10.1073/pnas.1215935110
  • Solt LA, Wang Y, Banerjee S, Hughes T, Kojetin DJ, Lundasen T, Shin Y, Liu J, Cameron MD, Noel R, et al. Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature 2012; 485:62-8; PMID:22460951; http://dx.doi.org/10.1038/nature11030
  • Robidoux J, Martin TL, Collins S. Beta-adrenergic receptors and regulation of energy expenditure: a family affair. Annu Rev Pharmacol Toxicol 2004; 44:297-323; PMID:14744248; http://dx.doi.org/10.1146/annurev.pharmtox.44.101802.121659