1,156
Views
18
CrossRef citations to date
0
Altmetric
Author's View

HIF-1 is a critical target of pancreatic cancer

Article: e1026535 | Received 27 Feb 2015, Accepted 27 Feb 2015, Published online: 27 Jul 2015

References

  • Zhao X, Gao S, Ren H, Sun W, Zhang H, Sun J, Yang S, Hao J. Hypoxia-inducible factor-1 promotes pancreatic ductal adenocarcinoma invasion and metastasis by activating transcription of the actin-bundling protein fascin. Cancer Res 2014; 74(9):2455-64; PMID:24599125; http://dx.doi.org/10.1158/0008-5472.CAN-13-3009
  • Zhao T, Ren H, Li J, Chen J, Zhang H, Xin W, Sun Y, Sun L, Yang Y, Sun J, et al. LASP1 Is a HIF1alpha Target Gene Critical for Metastasis of Pancreatic Cancer. Cancer Res 2015; 75(1):111-9; PMID:25385028; http://dx.doi.org/10.1158/0008-5472.CAN-14-2040
  • Zhao T, Gao S, Wang X, Liu J, Duan Y, Yuan Z, Sheng J, Li S, Wang F, Yu M, et al. Hypoxia-inducible factor-1alpha regulates chemotactic migration of pancreatic ductal adenocarcinoma cells through directly transactivating the CX3CR1 gene. PloS One 2012; 7(8):e43399; PMID:22952674; http://dx.doi.org/10.1371/journal.pone.0043399
  • Ren H, Zhao T, Sun J, Wang X, Liu J, Gao S, Yu M, Hao J. The CX3CL1/CX3CR1 reprograms glucose metabolism through HIF-1 pathway in pancreatic adenocarcinoma. J Cell Biochem 2013; 114(11):2603-11; PMID:23857671; http://dx.doi.org/10.1002/jcb.24608
  • Zhang H, Chen J, Liu F, Gao C, Wang X, Zhao T, Liu J, Gao S, Zhao X, Ren H, et al. CypA, a gene downstream of HIF-1alpha, promotes the development of PDAC. PloS One 2014; 9(3):e92824; PMID:24662981; http://dx.doi.org/10.1371/journal.pone.0092824
  • Somasundar P, Yu AK, Vona-Davis L, McFadden DW. Differential effects of leptin on cancer in vitro. J Surgical Res 2003; 113(1):50-5; PMID:12943810; http://dx.doi.org/10.1016/S0022-4804(03)00166-5
  • Ren H, Jia L, Zhao T, Zhang H, Chen J, Yang S, Liu J, Yu M, Hao J. Hypoxia inducible factor (HIF)-1alpha directly activates leptin receptor (Ob-R) in pancreatic cancer cells. Cancer Lett 2014; 354(1):172-80; PMID:25130171; http://dx.doi.org/10.1016/j.canlet.2014.08.001
  • Wang X, Liu Y, Ren H, Yuan Z, Li S, Sheng J, Zhao T, Chen Y, Liu F, Wang F, et al. Polymorphisms in the hypoxia-inducible factor-1alpha gene confer susceptibility to pancreatic cancer. Cancer Biol Therapy 2011; 12(5):383-7; PMID:21709439; http://dx.doi.org/10.4161/cbt.12.5.15982
  • Koh MY, Spivak-Kroizman T, Venturini S, Welsh S, Williams RR, Kirkpatrick DL, Powis G. Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1alpha. Mol Cancer Therapeut 2008; 7(1):90-100; PMID:18202012; http://dx.doi.org/10.1158/1535-7163.MCT-07-0463
  • Kepp O, Senovilla L, Kroemer G. Immunogenic cell death inducers as anticancer agents. Oncotarget 2014; 5(14):5190-1; PMID:25114034

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.