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OncoImmunology Volume 5, 2016 - Issue 5
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Tetraspanin CD81, a modulator of immune suppression in cancer and metastasis

Felipe Vences-CatalánDepartment of Medicine, Division of Oncology, Stanford University Medical Center, Stanford, CA, USA
,
Ranjani RajapaksaDepartment of Medicine, Division of Oncology, Stanford University Medical Center, Stanford, CA, USA
,
Minu K. SrivastavaDepartment of Medicine, Division of Oncology, Stanford University Medical Center, Stanford, CA, USA
,
Aurelien MarabelleDepartment of Medicine, Division of Oncology, Stanford University Medical Center, Stanford, CA, USA
,
Chiung-Chi KuoDepartment of Medicine, Division of Oncology, Stanford University Medical Center, Stanford, CA, USA
,
Ronald LevyDepartment of Medicine, Division of Oncology, Stanford University Medical Center, Stanford, CA, USA
&
Shoshana LevyDepartment of Medicine, Division of Oncology, Stanford University Medical Center, Stanford, CA, USACorrespondence[email protected]
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Article: e1120399 | Received 09 Nov 2015, Accepted 09 Nov 2015, Published online: 19 Apr 2016

References

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  • Mittelbrunn M, Yanez-Mo M, Sancho D, Ursa A, Sanchez-Madrid F. Cutting edge: dynamic redistribution of tetraspanin CD81 at the central zone of the immune synapse in both T lymphocytes and APC. J Immunol 2002; 169:6691-95; PMID:12471100; http://dx.doi.org/10.4049/jimmunol.169.12.6691
  • van Zelm MC, Smet J, Adams B, Mascart F, Schandene L, Janssen F, Ferster A, Kuo CC, Levy S, van Dongen JJ, van der Burg M. CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency. J Clin Invest 2010; 120:1265-74; PMID:20237408; http://dx.doi.org/10.1172/JCI39748
  • Maecker HT, Levy S. Normal lymphocyte development but delayed humoral immune response in CD81-null mice. J Exp Med 1997; 185:1505-10; PMID:9126932; http://dx.doi.org/10.1084/jem.185.8.1505
  • Levy S. Function of the tetraspanin molecule CD81 in B and T cells. Immunol Res 2014; 58:179-85; PMID:24522698; http://dx.doi.org/10.1007/s12026-014-8490-7

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