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Regulatory T cells do not suppress rather activate human basophils by IL-3 and STAT5-dependent mechanisms

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Article: 1773193 | Received 19 May 2020, Accepted 20 May 2020, Published online: 05 Jun 2020

References

  • Karasuyama H, Miyake K, Yoshikawa S, Yamanishi Y. Multifaceted roles of basophils in health and disease. J Allergy Clin Immunol. 2018;142:370–3. PMID: 29247714. doi:10.1016/j.jaci.2017.10.042.
  • Pere H, Tanchot C, Bayry J, Terme M, Taieb J, Badoual C, Adotevi O, Merillon N, Marcheteau E, Quillien VR, et al. Comprehensive analysis of current approaches to inhibit regulatory T cells in cancer. Oncoimmunology. 2012;1:326–333. PMID: 22737608. doi:10.4161/onci.18852.
  • Romano M, Fanelli G, Albany CJ, Giganti G, Past LG. Present, and future of regulatory T cell therapy in transplantation and autoimmunity. Front Immunol. 2019;10:43. PMID: 30804926. doi:10.3389/fimmu.2019.00043.
  • Wing JB, Tanaka A, Sakaguchi S. Human FOXP3(+) regulatory T cell heterogeneity and function in autoimmunity and cancer. Immunity. 2019;50:302–316. PMID: 30784578. doi:10.1016/j.immuni.2019.01.020.
  • Sharma M, Das M, Stephen-Victor E, Galeotti C, Karnam A, Maddur MS, Bruneval P, Kaveri SV, Bayry J. Regulatory T cells induce activation rather than suppression of human basophils. Sci Immunol. 2018;3:eaan0829. PMID: 29802207. doi:10.1126/sciimmunol.aan0829.
  • Stephen-Victor E, Das M, Sharma M, Galeotti C, Fohrer-Ting H, Sendid B, Darnige L, Terris B, Badoual C, Bruneval P, et al. Demystification of enigma on antigen-presenting cell features of human basophils: data from secondary lymphoid organs. Haematologica. 2017;102:e233–e237. PMID: 28209657. doi:10.3324/haematol.2016.163451.
  • De Monte L, Reni M, Tassi E, Clavenna D, Papa I, Recalde H, Braga M, Di Carlo V, Doglioni C, Protti MP. Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer. J Exp Med. 2011;208:469–478. PMID: 21339327. doi:10.1084/jem.20101876.
  • De Monte L, Wörmann S, Brunetto E, Heltai S, Magliacane G, Reni M, Paganoni AM, Recalde H, Mondino A, Falconi M, et al. Basophil recruitment into tumor-draining lymph nodes correlates with Th2 inflammation and reduced survival in pancreatic cancer patients. Cancer Res. 2016;76:1792–1803. PMID: 26873846. doi:10.1158/0008-5472.CAN-15-1801-T.
  • Bromley SK, Mempel TR, Luster AD. Orchestrating the orchestrators: chemokines in control of T cell traffic. Nat Immunol. 2008;9:970–980. PMID: 18711434. doi:10.1038/ni.f.213.
  • Li F, Sutherland MK, Yu C, Walter RB, Westendorf L, Valliere-Douglass J, Pan L, Cronkite A, Sussman D, Klussman K, et al. Characterization of SGN-CD123A, A potent CD123-directed antibody-drug conjugate for acute myeloid leukemia. Mol Cancer Ther. 2018;17:554–564. PMID: 29142066. doi:10.1158/1535-7163.MCT-17-0742.