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Research Paper

A novel recombinant vaccine protecting mice against abrin intoxication

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Pages 1361-1367 | Received 10 Oct 2014, Accepted 11 Dec 2014, Published online: 18 Jun 2015

References

  • Han YH, Gao S, Xin WW, Kang L, Wang JL. A recombinant mutant abrin A chain expressed in Escherichia coli can be used as an effective vaccine candidate. Hum Vaccin 2011; 7:838-44; PMID:21817853; http://dx.doi.org/10.4161/hv.7.8.16258
  • Surendranath K, Karande AA. A neutralizing antibody to the a chain of abrin inhibits abrin toxicity both in vitro and in vivo. Clin Vaccine Immunol 2008; 15:737-43; PMID:18353919; http://dx.doi.org/10.1128/CVI.00254-07
  • Balali-Mood M, Moshiri M, Etemad L. Medical aspects of bio-terrorism. Toxicon 2013; 69:131-42; PMID:23339855; http://dx.doi.org/10.1016/j.toxicon.2013.01.005
  • Kende M, Yan C, Hewetson J, Frick MA, Rill WL, Tammariello R. Oral immunization of mice with ricin toxoid vaccine encapsulated in polymeric microspheres against aerosol challenge. Vaccine 2002; 20:1681-91; PMID:11858879; http://dx.doi.org/10.1016/S0264-410X(01)00484-4
  • Griffiths GD, Lindsay CD, Allenby AC, Bailey SC, Scawin JW, Rice P, Upshall DG. Protection against inhalation toxicity of ricin and abrin by immunisation. Hum Exp Toxicol 1995; 14:155-64; PMID:7779439; http://dx.doi.org/10.1177/096032719501400201
  • Hu WG, Yin J, Chau D, Negrych LM, Cherwonogrodzky JW. Humanization and characterization of an anti-ricin neutralization monoclonal antibody. PLoS One 2012; 7:e45595; PMID:23049820; http://dx.doi.org/10.1371/journal.pone.0045595
  • Zhang T, Kang L, Gao S, Xin W, Yang H, Wang JH, Guo M, Wang J. Truncated abrin A chain expressed in Escherichia coli: A promising vaccine candidate. Hum Vaccin Immunother 2014; 10:2648-55; PMID: 25483485; http://dx.doi.org/10.4161/hv.29645
  • Vallera DA, Burns LJ, Frankel AE, Sicheneder AR, Gunther R, Gajl-Peczalska K, Pennell CA, Kersey JH. Laboratory preparation of a deglycosylated ricin toxin A chain containing immunotoxin directed against a CD7 T lineage differentiation antigen for phase I human clinical studies involving T cell malignancies. J Immunol Methods 1996; 197:69-83; PMID:8890895; http://dx.doi.org/10.1016/0022-1759(96)00127-5
  • Carra JH, Wannemacher RW, Tammariello RF, Lindsey CY, Dinterman RE, Schokman RD, Smith LA. Improved formulation of a recombinant ricin A-chain vaccine increases its stability and effective antigenicity. Vaccine 2007; 25:4149-58; PMID:17408819; http://dx.doi.org/10.1016/j.vaccine.2007.03.011
  • Kende M, Tan X, Wlazlowski C, Williams R, Lindsey C, Del Giudice G. Enhancement of intranasal vaccination with recombinant chain A ricin vaccine (rRV) in mice by the mucosal adjuvants LTK63 and LTR72. Vaccine 2007; 25:3219-27; PMID:17343960; http://dx.doi.org/10.1016/j.vaccine.2007.01.036
  • Schindler J, Gajavelli S, Ravandi F, Shen Y, Parekh S, Braunchweig I, Barta S, Ghetie V, Vitetta E, Verma A. A phase I study of a combination of anti-CD19 and anti-CD22 immunotoxins (Combotox) in adult patients with refractory B-lineage acute lymphoblastic leukaemia. Br J Haematol 2011; 154:471-6; PMID:21732928; http://dx.doi.org/10.1111/j.1365-2141.2011.08762.x
  • Legler PM, Brey RN, Smallshaw JE, Vitetta ES, Millard CB. Structure of RiVax: a recombinant ricin vaccine. Acta Crystallogr D Biol Crystallogr 2011; 67:826-30; PMID:21904036; http://dx.doi.org/10.1107/S0907444911026771
  • McLain DE, Lewis BS, Chapman JL, Wannemacher RW, Lindsey CY, Smith LA. Protective effect of two recombinant ricin subunit vaccines in the New Zealand white rabbit subjected to a lethal aerosolized ricin challenge: survival, immunological response, and histopathological findings. Toxicol Sci 2012; 126:72-83; PMID:21987460; http://dx.doi.org/10.1093/toxsci/kfr274
  • Vitetta ES, Smallshaw JE, Schindler J. Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine. Clin Vaccine Immunol 2012; 19:1697-9; PMID:22914366; http://dx.doi.org/10.1128/CVI.00381-12
  • Thomas JC, O'Hara JM, Hu L, Gao FP, Joshi SB, Volkin DB, Brey RN, Fang J, Karanicolas J, Mantis NJ, et al. Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigen. Hum Vaccin Immunother 2013; 9:744-52; PMID:23563512; http://dx.doi.org/10.4161/hv.22998
  • O'Hara JM, Brey RN, 3rd, Mantis NJ. Comparative efficacy of two leading candidate ricin toxin a subunit vaccines in mice. Clin Vaccine Immunol 2013; 20:789-94; PMID:23515013; http://dx.doi.org/10.1128/CVI.00098-13
  • Lemley PV, Wright DC. Mice are actively immunized after passive monoclonal antibody prophylaxis and ricin toxin challenge. Immunology 1992; 76:511-3; PMID:1526657
  • McGuinness CR, Mantis NJ. Characterization of a novel high-affinity monoclonal immunoglobulin G antibody against the ricin B subunit. Infect Immun 2006; 74:3463-70; PMID:16714577; http://dx.doi.org/10.1128/IAI.00324-06
  • Mantis NJ, McGuinness CR, Sonuyi O, Edwards G, Farrant SA. Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxication. Infect Immun 2006; 74:3455-62; PMID:16714576; http://dx.doi.org/10.1128/IAI.02088-05
  • Yermakova A, Mantis NJ. Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB). Vaccine 2011; 29:7925-35; PMID:21872634; http://dx.doi.org/10.1016/j.vaccine.2011.08.075
  • Hu WG, Yin J, Chau D, Hu CC, Lillico D, Yu J, Negrych LM, Cherwonogrodzky JW. Conformation-dependent high-affinity potent ricin-neutralizing monoclonal antibodies. Biomed Res Int 2013; 2013:471346; PMID:23484120
  • Mantis NJ. Vaccines against the category B toxins: Staphylococcal enterotoxin B, epsilon toxin and ricin. Adv Drug Deliv Rev 2005; 57:1424-39; PMID:15935880; http://dx.doi.org/10.1016/j.addr.2005.01.017
  • Smallshaw JE, Richardson JA, Pincus S, Schindler J, Vitetta ES. Preclinical toxicity and efficacy testing of RiVax, a recombinant protein vaccine against ricin. Vaccine 2005; 23:4775-84; PMID:15961194; http://dx.doi.org/10.1016/j.vaccine.2005.04.037
  • Pincus SH, Smallshaw JE, Song K, Berry J, Vitetta ES. Passive and active vaccination strategies to prevent ricin poisoning. Toxins (Basel) 2011; 3:1163-84; PMID:22069761; http://dx.doi.org/10.3390/toxins3091163
  • Medina-Bolivar F, Wright R, Funk V, Sentz D, Barroso L, Wilkins TD, Petri W Jr, Cramer CL. A non-toxic lectin for antigen delivery of plant-based mucosal vaccines. Vaccine 2003; 21:997-1005; PMID:12547614; http://dx.doi.org/10.1016/S0264-410X(02)00551-0
  • Liu W, Xu N, Yuan H, Li S, Liu L, Pu Z, Wan J, Wang H, Chang Y, Li R. Immunomodulatory Activity of Recombinant Ricin Toxin Binding Subunit B (RTB). Int J Mol Sci 2013; 14:12401-10; PMID:23765218; http://dx.doi.org/10.3390/ijms140612401