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Human Vaccines & Immunotherapeutics Volume 11, 2015 - Issue 3
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Case Report

Successful therapy with bevacizumab in a case of hereditary hemorrhagic telangiectasia

J KochanowskiDepartment of Internal Diseases; Voivodship Hospital; Opole, Poland
,
M SobieszczańskaDepartment of Pathophysiology; Wroclaw Medical University; Wroclaw, Poland
,
S TubekDepartment of Internal Diseases; Voivodship Hospital; Opole, PolandCorrespondence[email protected]
,
M ŻurekDepartment of Internal Diseases; Voivodship Hospital; Opole, Poland
&
J PawełczakDepartment of Internal Diseases; Voivodship Hospital; Opole, Poland
Pages 680-681 | Received 04 Aug 2014, Accepted 27 Nov 2014, Published online: 03 Apr 2015

References

  • Shovlin CL, Guttmacher AE, Buscarini E, Faughnan ME, Hyland RH, Westermann CJ, Kjeldsen AD, Plauchu H. Diagnostic criteria for hereditary hemorrhagic telangiectasia (rendu-osler-weber syndrome). Am J Med Genet 2000; 91:66-67; PMID:10751092
  • Dupuis-Girod S, Ginon I, Saurin JC, Marion D, Guillot E, Decullier E, Roux A, Carette MF, Gilbert-Dussardier B, Hatron PY, et al. Bevacizumab in patients with hereditary hemorrhagic telangiectasia and severe hepatic vascular malformations and high cardiac output. JAMA 2012 Mar 7; 307(9):948-55; PMID:22396517; http://dx.doi.org/10.1001/jama.2012.250
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  • Sadick H, Riedel F, Naim R, Goessler U, Hörmann K, Hafner M, Lux A. Patients with hereditary hemorrhagic telangiectasia have increased plasma levels of vascular endothelial growth factor and transforming growth factor-beta1 as well as high ALK1 tissue expression. Haematologica 2005 Jun; 90(6):818-28; PMID:15951295
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  • Tam BY, Wei K, Rudge JS, Hoffman J, Holash J, Park SK, Yuan J, Hefner C, Chartier C, Lee JS, et al. VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis. Nat Med 2006 Jul; 12(7):793-800; Epub 2006 Jun 25; PMID:16799557; http://dx.doi.org/10.1038/nm1428
  • Kelly RJ, Rixe O. Axitinib - a selective inhibitor of the vascular endothelial growth factor (VEGF) receptor. Target Oncol 2009 Dec; 4(4):297-305; Epub 2009 Oct 30; PMID:19876699; http://dx.doi.org/10.1007/s11523-009-0126-9
  • www.ema.europa.eu

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