Preclinical development of HIvax: Human survivin highly immunogenic vaccines

References

• Melief CJ, Kast WM. T-cell immunotherapy of tumors by adoptive transfer of cytotoxic T lymphocytes and by vaccination with minimal essential epitopes. Immunol Rev 1995; 145:167-77; PMID:7590825; http://dx.doi.org/10.1111/j.1600-065X.1995.tb00081.x.
   PubMed Web of Science ®Google Scholar
• Hung K, Hayashi R, Lafond-Walker A, Lowenstein C, Pardoll D, Levitsky H. The central role of CD4(+) T cells in the antitumor immune response. J Exp Med 1998; 188:2357-68; PMID:9858522; http://dx.doi.org/10.1084/jem.188.12.2357.
   PubMed Web of Science ®Google Scholar
• Oka Y, Tsuboi A, Elisseeva OA, Nakajima H, Fujiki F, Kawakami M, Shirakata T, Nishida S, Hosen N, Oji Y, et al. WT1 peptide cancer vaccine for patients with hematopoietic malignancies and solid cancers. Sci World J 2007; 7:649-65; PMID:17619750; http://dx.doi.org/10.1100/tsw.2007.119.
   PubMed Web of Science ®Google Scholar
• Hazama S, Nakamura Y, Takenouchi H, Suzuki N, Tsunedomi R, Inoue Y, Tokuhisa Y, Iizuka N, Yoshino S, Takeda K, et al. A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome. J Transl Med 2014; 12:63; PMID:24612787; http://dx.doi.org/10.1186/1479-5876-12-63.
   PubMed Web of Science ®Google Scholar
• Lennerz V, Gross S, Gallerani E, Sessa C, Mach N, Boehm S, Hess D, von Boehmer L, Knuth A, Ochsenbein AF, et al. Immunologic response to the survivin-derived multi-epitope vaccine EMD640744 in patients with advanced solid tumors. Cancer Immunol Immunother 2014; 63:381-94; PMID:24487961; http://dx.doi.org/10.1007/s00262-013-1516-5.
   PubMed Web of Science ®Google Scholar
• Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997; 3:917-21; PMID:9256286; http://dx.doi.org/10.1038/nm0897-917.
   PubMed Web of Science ®Google Scholar
• Velculescu VE, Madden SL, Zhang L, Lash AE, Yu J, Rago C, Lal A, Wang CJ, Beaudry GA, Ciriello KM, et al. Analysis of human transcriptomes. Nat Genet 1999; 23:387-8; PMID:10581018; http://dx.doi.org/10.1038/70487.
   PubMed Web of Science ®Google Scholar
• Grossman D, McNiff JM, Li F, Altieri DC. Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma. J Invest Dermatol 1999; 113:1076-81; PMID:10594755; http://dx.doi.org/10.1046/j.1523-1747.1999.00776.x.
   PubMed Web of Science ®Google Scholar
• Altieri DC. Survivin, versatile modulation of cell division and apoptosis in cancer. Oncogene 2003; 22:8581-9; PMID:14634620; http://dx.doi.org/10.1038/sj.onc.1207113.
   PubMed Web of Science ®Google Scholar
• Swana HS, Grossman D, Anthony JN, Weiss RM, Altieri DC. Tumor content of the antiapoptosis molecule survivin and recurrence of bladder cancer. N Engl J Med 1999; 341:452-3; PMID:10438269; http://dx.doi.org/10.1056/NEJM199908053410614.
   PubMed Web of Science ®Google Scholar
• Rohayem J, Diestelkoetter P, Weigle B, Oehmichen A, Schmitz M, Mehlhorn J, Conrad K, Rieber EP. Antibody response to the tumor-associated inhibitor of apoptosis protein survivin in cancer patients. Cancer Res 2000; 60:1815-7; PMID:10766164.
   PubMed Web of Science ®Google Scholar
• Andersen MH, Pedersen LO, Becker JC, Straten PT. Identification of a cytotoxic T lymphocyte response to the apoptosis inhibitor protein survivin in cancer patients. Cancer Res 2001; 61:869-72; PMID:11221872.
   PubMed Web of Science ®Google Scholar
• Casati C, Dalerba P, Rivoltini L, Gallino G, Deho P, Rini F, Belli F, Mezzanzanica D, Costa A, Andreola S, et al. The apoptosis inhibitor protein survivin induces tumor-specific CD8+ and CD4+ T cells in colorectal cancer patients. Cancer Res 2003; 63:4507-15; PMID:12907624.
   PubMed Web of Science ®Google Scholar
• Schmitz M, Diestelkoetter P, Weigle B, Schmachtenberg F, Stevanovic S, Ockert D, Rammensee HG, Rieber EP. Generation of survivin-specific CD8+ T effector cells by dendritic cells pulsed with protein or selected peptides. Cancer Res 2000; 60:4845-9; PMID:10987296.
   PubMed Web of Science ®Google Scholar
• Karanikas V, Soukou F, Kalala F, Kerenidi T, Grammoustianou ES, Gourgoulianis KI, Germenis AE. Baseline levels of CD8+ T cells against survivin and survivin-2B in the blood of lung cancer patients and cancer-free individuals. Clin Immunol 2008; 129:230-40; PMID:18789878; http://dx.doi.org/10.1016/j.clim.2008.07.024.
   PubMed Web of Science ®Google Scholar
• Reker S, Meier A, Holten-Andersen L, Svane IM, Becker JC, thor Straten P, Andersen MH. Identification of novel survivin-derived CTL epitopes. Cancer Biol Ther 2004; 3:173-9; PMID:14726703; http://dx.doi.org/10.4161/cbt.3.2.611.
   PubMed Web of Science ®Google Scholar
• Bertino P, Panigada M, Soprana E, Bianchi V, Bertilaccio S, Sanvito F, Rose AH, Yang H, Gaudino G, Hoffmann PR, et al. Fowlpox-based survivin vaccination for malignant mesothelioma therapy. Int J Cancer 2013; 133:612-23; PMID:23335100; http://dx.doi.org/10.1002/ijc.28048.
   PubMed Web of Science ®Google Scholar
• Kleinberg L, Lie AK, Florenes VA, Nesland JM, Davidson B. Expression of inhibitor-of-apoptosis protein family members in malignant mesothelioma. Hum Pathol 2007; 38:986-94; PMID:17350081; http://dx.doi.org/10.1016/j.humpath.2006.12.013.
   PubMed Web of Science ®Google Scholar
• Gregory SH, Mott S, Phung J, Lee J, Moise L, McMurry JA, Martin W, De Groot AS. Epitope-based vaccination against pneumonic tularemia. Vaccine 2009; 27:5299-306; PMID:19616492; http://dx.doi.org/10.1016/j.vaccine.2009.06.101.
   PubMed Web of Science ®Google Scholar
• McMurry JA, Gregory SH, Moise L, Rivera D, Buus S, De Groot AS. Diversity of Francisella tularensis Schu4 antigens recognized by T lymphocytes after natural infections in humans: identification of candidate epitopes for inclusion in a rationally designed tularemia vaccine. Vaccine 2007; 25:3179-91; PMID:17291638; http://dx.doi.org/10.1016/j.vaccine.2007.01.039.
   PubMed Web of Science ®Google Scholar
• Moise L, Buller RM, Schriewer J, Lee J, Frey SE, Weiner DB, Martin W, De Groot AS. VennVax, a DNA-prime, peptide-boost multi-T-cell epitope poxvirus vaccine, induces protective immunity against vaccinia infection by T cell response alone. Vaccine 2011; 29:501-11; PMID:21055490; http://dx.doi.org/10.1016/j.vaccine.2010.10.064.
   PubMed Web of Science ®Google Scholar
• Moss SF, Moise L, Lee DS, Kim W, Zhang S, Lee J, Rogers AB, Martin W, De Groot AS. HelicoVax: epitope-based therapeutic Helicobacter pylori vaccination in a mouse model. Vaccine 2011; 29:2085-91; PMID:21236233; http://dx.doi.org/10.1016/j.vaccine.2010.12.130.
   PubMed Web of Science ®Google Scholar
• Lladser A, Ljungberg K, Tufvesson H, Tazzari M, Roos AK, Quest AF, Kiessling R. Intradermal DNA electroporation induces survivin-specific CTLs, suppresses angiogenesis and confers protection against mouse melanoma. Cancer Immunol Immunother 2010; 59:81-92; PMID:19526360; http://dx.doi.org/10.1007/s00262-009-0725-4.
   PubMed Web of Science ®Google Scholar
• Andersen MH, Soerensen RB, Becker JC, thor Straten P. HLA-A24 and survivin: possibilities in therapeutic vaccination against cancer. J Transl Med 2006; 4:38; PMID:16948867; http://dx.doi.org/10.1186/1479-5876-4-38.
   PubMed Web of Science ®Google Scholar
• Wang QM, Sun SH, Hu ZL, Zhou FJ, Yin M, Xiao CJ, Zhang JC. Epitope DNA vaccines against tuberculosis: spacers and ubiquitin modulates cellular immune responses elicited by epitope DNA vaccine. Scand J Immunol 2004; 60:219-25; PMID:15320877; http://dx.doi.org/10.1111/j.0300-9475.2004.01442.x.
   PubMed Web of Science ®Google Scholar
• Turnquist HR, Vargas SE, McIlhaney MM, Li S, Wang P, Solheim JC. Calreticulin binds to the alpha1 domain of MHC class I independently of tapasin. Tissue Antigens 2002; 59:18-24; PMID:11972874; http://dx.doi.org/10.1034/j.1399-0039.2002.590104.x.
   PubMed Web of Science ®Google Scholar
• Livingston B, Crimi C, Newman M, Higashimoto Y, Appella E, Sidney J, Sette A. A rational strategy to design multiepitope immunogens based on multiple Th lymphocyte epitopes. J Immunol 2002; 168:5499-506; http://dx.doi.org/10.4049/jimmunol.168.11.5499.
   PubMed Web of Science ®Google Scholar
• Cousens LP, Su Y, McClaine E, Li X, Terry F, Smith R, Lee J, Martin W, Scott DW, De Groot AS. Application of IgG-derived natural Treg epitopes (IgG Tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetes. J Diabetes Res 2013; 2013:621693; PMID:23710469; http://dx.doi.org/10.1155/2013/621693.
   PubMed Web of Science ®Google Scholar
• De Groot AS. Do Tregitopes have the potential to impact the current treatment landscape of autoimmune diseases? Expert Rev Clin Immunol 2013; 9:1155-7; PMID:24215404; http://dx.doi.org/10.1586/1744666X.2013.858602.
   PubMed Web of Science ®Google Scholar
• Su Y, Rossi R, De Groot AS, Scott DW. Regulatory T cell epitopes (Tregitopes) in IgG induce tolerance in vivo and lack immunogenicity per se. J Leukoc Biol 2013; 94:377-83; PMID:23729499; http://dx.doi.org/10.1189/jlb.0912441.
   PubMed Web of Science ®Google Scholar
• Nezafat N, Ghasemi Y, Javadi G, Khoshnoud MJ, Omidinia E. A novel multi-epitope peptide vaccine against cancer: an in silico approach. J Theor Biol 2014; 349:121-34; PMID:24512916; http://dx.doi.org/10.1016/j.jtbi.2014.01.018.
   PubMed Web of Science ®Google Scholar
• Thiele F, Tao S, Zhang Y, Muschaweckh A, Zollmann T, Protzer U, Abele R, Drexler I. Modified Vaccinia Virus Ankara-Infected Dendritic Cells Present CD4+ T-Cell Epitopes by Endogenous Major Histocompatibility Complex Class II Presentation Pathways. J Virol 2015; 89:2698-709; PMID:25520512; http://dx.doi.org/10.1128/JVI.03244-14.
   PubMed Web of Science ®Google Scholar
• Jaraquemada D, Marti M, Long EO. An endogenous processing pathway in vaccinia virus-infected cells for presentation of cytoplasmic antigens to class II-restricted T cells. J Exp Med 1990; 172:947-54; PMID:2388037; http://dx.doi.org/10.1084/jem.172.3.947.
   PubMed Web of Science ®Google Scholar
• Nuchtern JG, Biddison WE, Klausner RD. Class II MHC molecules can use the endogenous pathway of antigen presentation. Nature 1990; 343:74-6; PMID:1967486; http://dx.doi.org/10.1038/343074a0.
   PubMed Web of Science ®Google Scholar
• Chen JL, Dawoodji A, Tarlton A, Gnjatic S, Tajar A, Karydis I, Browning J, Pratap S, Verfaille C, Venhaus RR, et al. NY-ESO-1 specific antibody and cellular responses in melanoma patients primed with NY-ESO-1 protein in ISCOMATRIX and boosted with recombinant NY-ESO-1 fowlpox virus. Int J Cancer 2014; 136(6):E590-601.
   PubMed Web of Science ®Google Scholar
• Odunsi K, Matsuzaki J, Karbach J, Neumann A, Mhawech-Fauceglia P, Miller A, Beck A, Morrison CD, Ritter G, Godoy H, et al. Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients. Proc Natl Acad Sci U S A 2012; 109:5797-802; PMID:22454499; http://dx.doi.org/10.1073/pnas.1117208109.
   PubMed Web of Science ®Google Scholar
• Cohen T, Moise L, Ardito M, Martin W, De Groot AS. A method for individualizing the prediction of immunogenicity of protein vaccines and biologic therapeutics: individualized T cell epitope measure (iTEM). J Biomed Biotechnol 2010; 2010; PMID:20706613.
   PubMedGoogle Scholar
• Pass HI, Stevens EJ, Oie H, Tsokos MG, Abati AD, Fetsch PA, Mew DJ, Pogrebniak HW, Matthews WJ. Characteristics of nine newly derived mesothelioma cell lines. Ann Thorac Surg 1995; 59:835-44; PMID:7695406; http://dx.doi.org/10.1016/0003-4975(95)00045-M.
   PubMed Web of Science ®Google Scholar
• Di Lullo G, Soprana E, Panigada M, Palini A, Agresti A, Comunian C, Milani A, Capua I, Erfle V, Siccardi AG. The combination of marker gene swapping and fluorescence-activated cell sorting improves the efficiency of recombinant modified vaccinia virus Ankara vaccine production for human use. J Virol Methods 2010; 163:195-204; PMID:19778556; http://dx.doi.org/10.1016/j.jviromet.2009.09.016.
   PubMed Web of Science ®Google Scholar
• Soprana E, Panigada M, Knauf M, Radaelli A, Vigevani L, Palini A, Villa C, Malnati M, Cassina G, Kurth R, et al. Joint production of prime/boost pairs of Fowlpox Virus and Modified Vaccinia Ankara recombinants carrying the same transgene. J Virol Methods 2011; 174:22-8; PMID:21419167; http://dx.doi.org/10.1016/j.jviromet.2011.03.013.
   PubMed Web of Science ®Google Scholar
• Robinson J, Mistry K, McWilliam H, Lopez R, Parham P, Marsh SG. The IMGT/HLA database. Nucleic Acids Res 2011; 39:D1171-6; PMID:21071412; http://dx.doi.org/10.1093/nar/gkq998.
   PubMed Web of Science ®Google Scholar
• Edgar RC. Search and clustering orders of magnitude faster than BLAST. Bioinformatics 2010; 26:2460-1; PMID:20709691; http://dx.doi.org/10.1093/bioinformatics/btq461.
   PubMed Web of Science ®Google Scholar