The role of B. pertussis vaccine antigen gene variants in pertussis resurgence and possible consequences for vaccine development

References

• Burns DL, Meade BD, Messionnier NE. Pertussis Resurgence: Perspectives From the Working Group Meeting on Pertussis on the Causes, Possible Paths Forward, and Gaps in Our Knowledge. J Infect Dis 2014; 209:S32-S5; PMID:24626870; http://dx.doi.org/10.1093/infdis/jit491
   PubMed Web of Science ®Google Scholar
• Belcher T, Preston A. Bordetella pertussis evolution in the (functional) genomics era. Pathog Dis 2015; 73:ftv064; PMID:26297914; http://dx.doi.org/10.1093/femspd/ftv064
   PubMed Web of Science ®Google Scholar
• Rendi-Wagner P, Kundi M, Mikolasek A, Vecsei A, Fruhwirth M, Kollaritsch H. Hospital-based active surveillance of childhood pertussis in Austria from 1996 to 2003: estimates of incidence and vaccine effectiveness of whole-cell and acellular vaccine. Vaccine 2006; 24:5960-5; PMID:16757063; http://dx.doi.org/10.1016/j.vaccine.2006.05.011
   PubMed Web of Science ®Google Scholar
• Witt MA, Arias L, Katz PH, Truong ET, Witt DJ. Reduced risk of pertussis among persons ever vaccinated with whole cell pertussis vaccine compared to recipients of acellular pertussis vaccines in a large US cohort. Clin Infect Dis 2013; 56:1248-54; PMID:23487373; http://dx.doi.org/10.1093/cid/cit046
   PubMed Web of Science ®Google Scholar
• Witt MA, Katz PH, Witt DJ. Unexpectedly limited durability of immunity following acellular pertussis vaccination in preadolescents in a North American outbreak. Clin Infect Dis 2012; 54:1730-5; PMID:22423127; http://dx.doi.org/10.1093/cid/cis287
   PubMed Web of Science ®Google Scholar
• Ross PJ, Sutton CE, Higgins S, Allen AC, Walsh K, Misiak A, Lavelle EC, McLoughlin RM, Mills KH. Relative contribution of Th1 and Th17 cells in adaptive immunity to Bordetella pertussis: towards the rational design of an improved acellular pertussis vaccine. PLoS pathogens 2013; 9:e1003264; PMID:23592988; http://dx.doi.org/10.1371/journal.ppat.1003264
   PubMed Web of Science ®Google Scholar
• Warfel JM, Zimmerman LI, Merkel TJ. Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model. Proc Natl Acad of Sci 2013; 111:787-92; http://dx.doi.org/10.1073/pnas.1314688110
   PubMed Web of Science ®Google Scholar
• Poolman JT. Shortcomings of pertussis vaccines: why we need a third generation vaccine. Expert Rev Vaccines 2014; 13:1159-62; PMID:25089373; http://dx.doi.org/10.1586/14760584.2014.944902
   PubMed Web of Science ®Google Scholar
• Mooi FR. Bordetella pertussis and vaccination: the persistence of a genetically monomorphic pathogen. Infect Genet Evol 2010; 10:36-49; PMID:19879977; http://dx.doi.org/10.1016/j.meegid.2009.10.007
   PubMed Web of Science ®Google Scholar
• Mooi FR, Van Der Maas NA, De Melker HE. Pertussis resurgence: waning immunity and pathogen adaptation - two sides of the same coin. Epidemiol Infect 2014; 142:685-94; PMID:23406868; http://dx.doi.org/10.1017/S0950268813000071
   PubMed Web of Science ®Google Scholar
• Bart MJ, Harris SR, Advani A, Arakawa Y, Bottero D, Bouchez V, Cassiday PK, Chiang CS, Dalby T, Fry NK, et al. Global population structure and evolution of Bordetella pertussis and their relationship with vaccination. Mbio 2014; 5:e01074; PMID:24757216; http://dx.doi.org/10.1128/mBio.01074-14
   PubMed Web of Science ®Google Scholar
• Sealey KL, Harris SR, Fry NK, Hurst LD, Gorringe AR, Parkhill J, Preston A. Genomic Analysis of Isolates From the United Kingdom 2012 Pertussis Outbreak Reveals That Vaccine Antigen Genes Are Unusually Fast Evolving. J Infect Dis 2015; 212:294-301; PMID:25489002; http://dx.doi.org/10.1093/infdis/jiu665
   PubMed Web of Science ®Google Scholar
• van Gent M, Bart MJ, van der Heide HG, Heuvelman KJ, Mooi FR. Small mutations in Bordetella pertussis are associated with selective sweeps. PloS One 2012; 7:e46407; PMID:23029513; http://dx.doi.org/10.1371/journal.pone.0046407
   PubMed Web of Science ®Google Scholar
• Martin SW, Pawloski L, Williams M, Weening K, DeBolt C, Qin X, Reynolds L, Kenyon C, Giambrone G, Kudish K, et al. Pertactin-negative Bordetella pertussis strains: evidence for a possible selective advantage. Clin Infect Dis 2015; 60:223-7; PMID:25301209; http://dx.doi.org/10.1093/cid/ciu788
   PubMed Web of Science ®Google Scholar
• Hegerle N, Dore G, Guiso N. Pertactin deficient Bordetella pertussis present a better fitness in mice immunized with an acellular pertussis vaccine. Vaccine 2014; 32:6597-600; PMID:25312274; http://dx.doi.org/10.1016/j.vaccine.2014.09.068
   PubMed Web of Science ®Google Scholar
• Safarchi A, Octavia S, Luu LD, Tay CY, Sintchenko V, Wood N, Marshall H, McIntyre P, Lan R. Pertactin negative Bordetella pertussis demonstrates higher fitness under vaccine selection pressure in a mixed infection model. Vaccine 2015; 33:6277-81; PMID:26432908; http://dx.doi.org/10.1016/j.vaccine.2015.09.064
   PubMed Web of Science ®Google Scholar
• Vaughan K, Seymour E, Peters B, Sette A. Substantial gaps in knowledge of Bordetella pertussis antibody and T cell epitopes relevant for natural immunity and vaccine efficacy. Hum Immunol 2014; 75:440-51; PMID:24530743; http://dx.doi.org/10.1016/j.humimm.2014.02.013
   PubMed Web of Science ®Google Scholar
• Shuel M, Jamieson FB, Tang P, Brown S, Farrell D, Martin I, Stoltz J, Tsang RS. Genetic analysis of Bordetella pertussis in Ontario, Canada reveals one predominant clone. Int J Infect Dis 2013; 17:e413-7; PMID:23352492; http://dx.doi.org/10.1016/j.ijid.2012.12.015
   PubMedGoogle Scholar
• Vaughan TE, Pratt CB, Sealey K, Preston A, Fry NK, Gorringe AR. Plasticity of fimbrial genotype and serotype within populations of Bordetella pertussis: analysis by paired flow cytometry and genome sequencing. Microbiol 2014; 160:2030-44; PMID:25028460; http://dx.doi.org/10.1099/mic.0.079251-0
   PubMed Web of Science ®Google Scholar
• da Silva FR, Napoleao-Pego P, De-Simone SG. Identification of linear B epitopes of pertactin of Bordetella pertussis induced by immunization with whole and acellular vaccine. Vaccine 2014; 32:6251-8; PMID:25252193; http://dx.doi.org/10.1016/j.vaccine.2014.09.019
   PubMed Web of Science ®Google Scholar
• Han WG, Helm K, Poelen MM, Otten HG, van Els CA. Ex vivo peptide-MHC II tetramer analysis reveals distinct end-differentiation patterns of human pertussis-specific CD4(+) T cells following clinical infection. Clin Immunol 2015; 157:205-15; PMID:25728491; http://dx.doi.org/10.1016/j.clim.2015.02.009
   PubMed Web of Science ®Google Scholar
• Valentini D, Ferrara G, Advani R, Hallander HO, Maeurer MJ. Serum reactome induced by Bordetella pertussis infection and Pertussis vaccines: qualitative differences in serum antibody recognition patterns revealed by peptide microarray analysis. BMC Immunol 2015; 16:40; PMID:26129684; http://dx.doi.org/10.1186/s12865-015-0090-3
   PubMed Web of Science ®Google Scholar
• Higgs R, Higgins SC, Ross PJ, Mills KH. Immunity to the respiratory pathogen Bordetella pertussis. Mucosal Immunol 2012; 5:485-500; PMID:22718262
   PubMed Web of Science ®Google Scholar