Fifteen years of epidemiologic, virologic and syndromic influenza surveillance: A focus on type B virus and the effects of vaccine mismatch in Liguria region, Italy

References

• Cromer D, van Hoek AJ, Jit M, Edmunds WJ, Fleming D, Miller E. The burden of influenza in England by age and clinical risk group: a statistical analysis to inform vaccine policy. J Infect 2014; 68(4):363-71; PMID:24291062; http://dx.doi.org/10.1016/j.jinf.2013.11.013
   PubMed Web of Science ®Google Scholar
• Nair H, Brooks WA, Katz M, Roca A, Berkley JA, Madhi SA, Simmerman JM, Gordon A, Sato M, Howie S, et al. Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis. Lancet 2011; 378:1917-30; PMID:22078723; http://dx.doi.org/10.1016/S0140-6736(11)61051-9
   PubMed Web of Science ®Google Scholar
• World Health Organization. Media Center. Influenza (seasonal). Fact Sheet no 211. March 2014
   Google Scholar
• Keech M, Beardsworth P. The impact of influenza on working days lost: a review of the literature. Pharmacoeconomics 2008; 26:911-24; PMID:18850761; http://dx.doi.org/10.2165/00019053-200826110-00004
   PubMed Web of Science ®Google Scholar
• Tafalla M, Buijssen M, Geets R, Vonk Noordegraaf-Schouten M. A comprehensive review of the epidemiology and disease burden of Influenza B in 9 European countries. Hum Vaccin Immunother 2016; 12(4):993-1002; PMID:26890005; http://dx.doi.org/10.1080/21645515.2015.1111494
   PubMed Web of Science ®Google Scholar
• Finkelman BS, Viboud C, Koelle K, Ferrari MJ, Bharti N, Grenfell BT. Global patterns in seasonal activity of influenza A/H3N2, A/H1N1,and B from 1997 to 2005: viral coexistence and latitudinal gradients. PLoS ONE 2007; 2:e1296; PMID:18074020; http://dx.doi.org/10.1371/journal.pone.0001296
   PubMed Web of Science ®Google Scholar
• Thompson WW, Shay DK, Weintraub E, Brammer L, Cox N, Anderson LJ, Fukuda K. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 2003; 289:179-186; PMID:12517228; http://dx.doi.org/10.1001/jama.289.2.179
   PubMed Web of Science ®Google Scholar
• Thompson WW, Shay DK, Weintraub E, Brammer L, Bridges CB, Cox NJ, Fukuda K. Influenza-associated hospitalizations in the United States. JAMA 2004; 292:1333-1340; http://dx.doi.org/10.1001/jama.292.11.1333
   PubMed Web of Science ®Google Scholar
• Kilbourne ED. Influenza pandemics of the 20th century. Emerg Infect Dis 2006; 12:9-14; PMID:16494710; http://dx.doi.org/10.3201/eid1201.051254
   PubMed Web of Science ®Google Scholar
• Paul Glezen W, Schmier JK, Kuehn CM, Ryan KJ, Oxford J. The burden of influenza B: a structured literature review. Am J Public Health 2013; 103:e43-e51; PMID:23327249; http://dx.doi.org/10.2105/AJPH.2012.301137
   PubMed Web of Science ®Google Scholar
• Camilloni B, Neri M, Lepri E, Basileo M, Sigismondi N, Puzelli S, Donatelli I, Iorio AM. An influenza B outbreak during the 2007/2008 winter among appropriately immunized elderly people living in a nursing home. Vaccine 2010; 28(47):7536-41; PMID:20846530; http://dx.doi.org/10.1016/j.vaccine.2010.08.064
   PubMed Web of Science ®Google Scholar
• Grant KA, Carville K, Fielding JE, Barr IG, Riddell MA, Tran T, Kelly HA. High proportion of influenza B characterizes the 2008 influenza season in Victoria. Communicable Diseases Intelligence Quarterly Report 2009; 33(3):328-36; PMID:20043604
   PubMedGoogle Scholar
• Yin-Coggrave M, Kadri Z. Type B influenza in Singapore. Singapore Medical J 1965; 6(2):71-4
   Google Scholar
• Burnet FM, Stone JD, Anderson SG. An epidemic of influenza B in Australia. Lancet 1946; 247(6405):807-11
   Google Scholar
• Tramuto F, Orsi A, Maida CM, Costantino C, Trucchi C, Alicino C, Vitale F, Ansaldi F. The Molecular Epidemiology and Evolutionary Dynamics of Influenza B Virus in Two Italian Regions during 2010–2015: The Experience of Sicily and Liguria. Int J Mol Sci 2016; 17(4):549; PMID:27089319; http://dx.doi.org/10.3390/ijms17040549
   PubMed Web of Science ®Google Scholar
• Matsuzaki Y, Sugawara K, Takashita E, Muraki Y, Hongo S, Katsushima N, Mizuta K, Nishimura H. Genetic diversity of influenza B virus: The frequent reassortment and cocirculation of the genetically distinct reassortant viruses in a community. J Med Virol 2004; 74:132-140; PMID:15258979; http://dx.doi.org/10.1002/jmv.20156
   PubMed Web of Science ®Google Scholar
• Bedford T, Riley S, Barr IG, Broor S, Chadha M, Cox NJ, Daniels RS, Gunasekaran CP, Hurt AC, Kelso A, et al. Global circulation patterns of seasonal influenza viruses vary with antigenic drift. Nature 2015; 523(7559):217-20; PMID:26053121; http://dx.doi.org/10.1038/nature14460
   PubMed Web of Science ®Google Scholar
• Irving SA, Patel DC, Kieke BA, Donahue JG, Vandermause MF, Shay DK, Belongia EA. Comparison of clinical features and outcomes of medically attended influenza A and influenza B in a defined population over four seasons: 2004–2005 through 2007–2008. Influenza Other Respir Viruses 2012; 6:37-43; PMID:21668663; http://dx.doi.org/10.1111/j.1750-2659.2011.00263.x
   PubMed Web of Science ®Google Scholar
• Biere B, Bauer B, Schweiger B. Differentiation of influenza B virus lineages Yamagata and Victoria by real-time PCR. J Clin Microbiol 2010; 48:1425-1427; PMID:20107085; http://dx.doi.org/10.1128/JCM.02116-09
   PubMed Web of Science ®Google Scholar
• Moa AM, Muscatello DJ, Turner RM, MacIntyre CR. Epidemiology of Influenza B in Australia: 2001–2014 Influenza Seasons. Influenza Other Respir Viruses 2016 (in press); PMID:27650482; http://dx.doi.org/10.1111/irv.12432
   PubMed Web of Science ®Google Scholar
• Belshe RB, Coelingh K, Ambrose CS, Woo JC, Wu X. Efficacy of live attenuated influenza vaccine in children against influenza B viruses by lineage and antigenic similarity. Vaccine 2010; 28:2149-56; PMID:20003926; http://dx.doi.org/10.1016/j.vaccine.2009.11.068
   PubMed Web of Science ®Google Scholar
• Belshe RB. The need for quadrivalent vaccine against seasonal influenza. Vaccine 2010; 28(Suppl 4):D45-53; PMID:20713260; http://dx.doi.org/10.1016/j.vaccine.2010.08.028
   PubMed Web of Science ®Google Scholar
• Puzelli S, Frezza F, Fabiani C, Ansaldi F, Campitelli L, Lin YP, Gregory V, Bennett M, D'Agaro P, Campello C, et al. Changes in the hemagglutinins and neuraminidases of human influenza B viruses isolated in Italy during the 2001–2002, 2002–2003, and 2003–2004 seasons. J Med Virol 2004; 74:29-40; PMID:15258965; http://dx.doi.org/10.1002/jmv.20225
   PubMed Web of Science ®Google Scholar
• Skowronski DM, Janjua NZ, Sabaiduc S, de Serres G, Winter AL, Gubbay JB, Dickinson JA, Fonseca K, Charest H, Bastien N, et al. Influenza A/subtype and B/lineage effectiveness estimates for the 2011–2012 trivalent vaccine: Cross-season and cross-lineage protection with unchanged vaccine. J Infect Dis 2014; 210:126-137; PMID:24446529; http://dx.doi.org/10.1093/infdis/jiu048
   PubMed Web of Science ®Google Scholar
• Lo YC, Chuang JH, Kuo HW, Huang WT, Hsu YF, Liu MT, Chen CH, Huang HH, Chang CH, Chou JH, et al. Surveillance and vaccine effectiveness of an influenza epidemic predominated by vaccine-mismatched influenza B/Yamagata-lineage viruses in Taiwan, 2011–2012 season. PLoS One 2013; 8:e58222; PMID:23472161; http://dx.doi.org/10.1371/journal.pone.0058222
   PubMed Web of Science ®Google Scholar
• Trucchi C, Paganino C, Orsi A, De Florentiis D, Ansaldi F. Influenza vaccination in the elderly: why are the overall benefits still hotly debated? J Prev Med Hyg 2015; 56(1):E37-43
   PubMedGoogle Scholar
• Rizzo C, Bella A. The impact of influenza virus B in Italy: myth or reality? J Prev Med Hyg 2016; 57(1):E23-7
   Google Scholar
• Caini S, Huang QS, Ciblak MA, Kusznierz G, Owen R, Wangchuk S, Henriques CM, Njouom R, Fasce RA, Yu H, et al. Global Influenza B Study. Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study. Influenza Other Respir Viruses 2015; 9(Suppl 1):3-12; PMID:26256290
   PubMed Web of Science ®Google Scholar
• Ansaldi F, D'Agaro P, De Florentiis D, Puzelli S, Lin YP, Gregory V, Bennett M, Donatelli I, Gasparini R, Crovari P, et al. Molecular characterization of influenza B viruses circulating in northern Italy during the 2001–2002 epidemic season. J Med Virol 2003; 70(3):463-9; PMID:12767012; http://dx.doi.org/10.1002/jmv.10418
   PubMed Web of Science ®Google Scholar
• Kanegae Y, Sugita S, Endo A, Ishida M, Senya S, Osako K, Nerome K, Oya A. Evolutionary pattern of the hemagglutinin gene of influenza B viruses isolated in Japan: cocirculating lineages in the same epidemic season. J Virol 1990; 64(6):2860-5; PMID:2335820
   PubMed Web of Science ®Google Scholar
• Rota PA, Wallis TR, Harmon MW, Rota JS, Kendal AP, Nerome K. Cocirculation of two distinct evolutionary lineages of influenza type B virus since 1983. Virology 1990; 175(1):59-68;
   PubMed Web of Science ®Google Scholar
  Rota PA, Hemphill ML, Whistler T, Regnery HL, Kendal AP. Antigenic and genetic characterization of the haemagglutinins of recent cocirculating strains of influenza B virus. J Gen Virol 1992; 73(Pt 10):2737-42; PMID:2309452; http://dx.doi.org/10.1016/0042-6822(90)90186-U
   PubMed Web of Science ®Google Scholar
• Lindstrom SE, Hiromoto Y, Nishimura H, Saito T, Nerome R, Nerome K. Comparative analysis of evolutionary mechanisms of the hemagglutinin and three internal protein genes of influenza B virus: multiple cocirculating lineages and frequent reassortment of the NP, M, and NS genes. J Virol 1999; 73(5):4413-26; PMID:10196339
   PubMed Web of Science ®Google Scholar
• Shaw MW, Xu X, Li Y, Normand S, Ueki RT, Kunimoto GY, Hall H, Klimov A, Cox NJ, Subbarao K. Reappearance and global spread of variants of influenza B/Victoria/2/87 lineage viruses in the 2000–2001 and 2001–2002 seasons. Virology 2002; 303(1):1-8; PMID:12482653; http://dx.doi.org/10.1006/viro.2002.1719
   PubMed Web of Science ®Google Scholar
• World Health Organization FluNet website. Available at: http://www.who.int/influenza/gisrs_laboratory/flunet/en/.
   Google Scholar
• Tisa V, Barberis I, Faccio V, Paganino C, Trucchi C, Martini M, Ansaldi F. Quadrivalent influenza vaccine: a new opportunity to reduce the influenza burden. J Prev Med Hyg. 2016; 57(1):E28-33; PMID:27346937
   PubMedGoogle Scholar
• Italian Ministry of Health. Operative protocol - Influenza season. 2015–2016. Available at: http://www.salute.gov.it/imgs/C_17_pubblicazioni_2418_allegato.pdf. Last access: 21/10/2016
   Google Scholar
• Gasparini R, Bonanni P, Amicizia D, Bella A, Donatelli I, Cristina ML, Panatto D, Lai PL. Influenza epidemiology in Italy two years after the 2009–2010 pandemic: need to improve vaccination coverage. Hum Vaccin Immunother 2013; 9(3):561-7; PMID:23292210; http://dx.doi.org/10.4161/hv.23235
   PubMed Web of Science ®Google Scholar
• Ansaldi F, Orsi A, Altomonte F, Bertone G, Parodi V, Carloni R, Moscatelli P, Pasero E, Oreste P, Icardi G. Emergency department syndromic surveillance system for early detection of 5 syndromes: a pilot project in a reference teaching hospital in Genoa, Italy. J Prev Med Hyg 2008; 49(4):131-5; PMID:19350960
   PubMedGoogle Scholar
• Ansaldi F, Orsi A, Trucchi C, De Florentiis D, Ceravolo A, Coppelli M, Schiaffino S, Turello V, Rosselli R, Carloni R, et al. Potential effect of PCV13 introduction on Emergency Department accesses for lower respiratory tract infections in elderly and at risk adults. Hum Vaccin Immunother 2015; 11(1):166-7; PMID:25483530; http://dx.doi.org/10.4161/hv.34419
   PubMed Web of Science ®Google Scholar
• Ansaldi F, Bacilieri S, Amicizia D, Valle L, Banfi F, Durando P, Sticchi L, Gasparini R, Icardi G, Crovari P. Antigenic characterisation of influenza B virus with a new microneutralisation assay: comparison to haemagglutination and sequence analysis. J Med Virol 2004; 74(1):141-6; PMID:15258980; http://dx.doi.org/10.1002/jmv.20157
   PubMed Web of Science ®Google Scholar
• Wiley DC, Skehel JJ. The structure and function of the hemagglutinin membrane glycoprotein of influenza virus. Annu Rev Biochem 1987; 56:365-94; PMID:3304138; http://dx.doi.org/10.1146/annurev.bi.56.070187.002053
   PubMed Web of Science ®Google Scholar
• Tamura K, Stecher G, Peterson D, Filipski A, Kumar S. MEGA6: molecular evolutionary genetics analysis version 6.0. Mol Biol Evol 2013; 30(12):2725-9; PMID:24132122; http://dx.doi.org/10.1093/molbev/mst197
   PubMed Web of Science ®Google Scholar