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Research Paper - Solicited

Component-resolved evaluation of the content of major allergens in therapeutic extracts for specific immunotherapy of honeybee venom allergy

, , , , , , , , , & show all
Pages 2482-2489 | Received 16 Mar 2017, Accepted 24 Apr 2017, Published online: 09 Jun 2017

References

  • Golden DB. Insect sting anaphylaxis. Immunol Allergy Clin North Am 2007; 27:261-72, vii; PMID:17493502; https://doi.org/10.1016/j.iac.2007.03.008
  • Rueff F , Przybilla B , Bilo MB , Muller U , Scheipl F , Seitz MJ , Aberer W , Bodzenta-Lukaszyk A , Bonifazi F , Campi P , et al. Clinical effectiveness of hymenoptera venom immunotherapy: a prospective observational multicenter study of the European academy of allergology and clinical immunology interest group on insect venom hypersensitivity. PloS one 2013; 8:e63233; PMID:23700415; https://doi.org/10.1371/journal.pone.0063233
  • Ollert M , Blank S . Anaphylaxis to Insect Venom Allergens: Role of Molecular Diagnostics. Curr Allergy Asthma Rep 2015; 15:527; https://doi.org/10.1007/s11882-015-0527-z
  • Bilo MB , Cinti B , Brianzoni MF , Braschi MC , Bonifazi M , Antonicelli L . Honeybee venom immunotherapy: a comparative study using purified and nonpurified aqueous extracts in patients with normal Basal serum tryptase concentrations. J Allergy 2012; 2012:869243; PMID:22287975; https://doi.org/10.1155/2012/869243
  • Bilo BM , Bonifazi F . Hymenoptera venom immunotherapy. Immunotherapy 2011; 3:229-46; PMID:21322761; https://doi.org/10.2217/imt.10.88
  • Van Vaerenbergh M , Debyser G , Devreese B , de Graaf DC . Exploring the hidden honeybee (Apis mellifera) venom proteome by integrating a combinatorial peptide ligand library approach with FTMS. J Proteomics 2014; 99:169-78; PMID:24606962; https://doi.org/10.1016/j.jprot.2013.04.039
  • Bilo MB , Antonicelli L , Bonifazi F . Purified vs. nonpurified venom immunotherapy. Curr Opin Allergy Clin Immunol 2010; 10:330-6; https://doi.org/10.1097/ACI.0b013e328339f2d1
  • Bilo MB , Severino M , Cilia M , Pio A , Casino G , Ferrarini E , Campodonico P , Milani M . The VISYT trial: Venom Immunotherapy Safety and Tolerability with purified vs nonpurified extracts. Ann Allergy Asthma Immunol 2009; 103:57-61; https://doi.org/10.1016/S1081-1206(10)60173-1 10.1016/S1081-1206(10)60144-5 10.1016/S1081-1206(10)60823-X
  • Larsen JN , Dreborg S . Standardization of allergen extracts. Methods Mol Med 2008; 138:133-45; PMID:18612605
  • Spillner E , Blank S , Jakob T . Hymenoptera allergens: from venom to “venome.” Front Immunol 2014; 5:77; PMID:24616722; https://doi.org/10.3389/fimmu.2014.00077
  • Frick M , Fischer J , Helbling A , Rueff F , Wieczorek D , Ollert M , Pfützner W , Müller S , Huss-Marp J , Dorn B , et al. Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy. J Allergy Clin Immunol 2016; 138:1663-71 e9; PMID:27372568; https://doi.org/10.1016/j.jaci.2016.04.024
  • Kohler J , Blank S , Muller S , Bantleon F , Frick M , Huss-Marp J , Lidholm J , Spillner E , Jakob T . Component resolution reveals additional major allergens in patients with honeybee venom allergy. J Allergy Clin Immunol 2014; 133:1383-9, 9 e1–6
  • Blank S , Seismann H , Michel Y , McIntyre M , Cifuentes L , Braren I , Grunwald T , Darsow U , Ring J , Bredehorst R , et al. Api m 10, a genuine A. mellifera venom allergen, is clinically relevant but underrepresented in therapeutic extracts. Allergy 2011; 66:1322-9
  • Müller UR . Insektenstichallergie: Klinik, Diagnostik und Therapie. Stuttgart, New York: Gustav Fischer Verlag, 1988
  • Grunwald T , Bockisch B , Spillner E , Ring J , Bredehorst R , Ollert MW . Molecular cloning and expression in insect cells of honeybee venom allergen acid phosphatase (Api m 3). J Allergy Clin Immunol 2006; 117:848-54; PMID:16630944; https://doi.org/10.1016/j.jaci.2005.12.1331
  • Seismann H , Blank S , Braren I , Greunke K , Cifuentes L , Grunwald T , Bredehorst R , Ollert M , Spillner E . Dissecting cross-reactivity in hymenoptera venom allergy by circumvention of alpha-1,3-core fucosylation. Mol Immunol 2010; 47:799-808; PMID:19896717; https://doi.org/10.1016/j.molimm.2009.10.005
  • Blank S , Seismann H , Bockisch B , Braren I , Cifuentes L , McIntyre M , Rühl D , Ring J , Bredehorst R , Ollert MW , et al. Identification, recombinant expression, and characterization of the 100 kDa high molecular weight hymenoptera venom allergens Api m 5 and Ves v 3. Journal of immunology 2010; 184:5403-13; https://doi.org/10.4049/jimmunol.0803709
  • Casset A , Mari A , Purohit A , Resch Y , Weghofer M , Ferrara R , Thomas WR , Alessandri C , Chen KW , de Blay F , et al. Varying allergen composition and content affects the in vivo allergenic activity of commercial Dermatophagoides pteronyssinus extracts. Int Arch Allergy Immunol 2012; 159:253-62; PMID:22722650; https://doi.org/10.1159/000337654
  • Curin M , Reininger R , Swoboda I , Focke M , Valenta R , Spitzauer S . Skin prick test extracts for dog allergy diagnosis show considerable variations regarding the content of major and minor dog allergens. Int Arch Allergy Immunol 2011; 154:258-63; PMID:20861648; https://doi.org/10.1159/000321113
  • Focke M , Marth K , Valenta R . Molecular composition and biological activity of commercial birch pollen allergen extracts. Eur J Clin Invest 2009; 39:429-36; PMID:19302561; https://doi.org/10.1111/j.1365-2362.2009.02109.x
  • Kespohl S , Maryska S , Zahradnik E , Sander I , Bruning T , Raulf-Heimsoth M . Biochemical and immunological analysis of mould skin prick test solution: current status of standardization. Clin Exp Allergy 2013; 43:1286-96; PMID:24152161; https://doi.org/10.1111/cea.12186
  • Schmidt H , Gelhaus C , Nebendahl M , Janssen O , Petersen A . Characterization of Phleum pratense pollen extracts by 2-D DIGE and allergen immunoreactivity. Proteomics 2010; 10:4352-62; PMID:21136590; https://doi.org/10.1002/pmic.201000451 10.1002/pmic.201000045
  • Van Vaerenbergh M , Cardoen D , Formesyn EM , Brunain M , Van Driessche G , Blank S , Spillner E , Verleyen P , Wenseleers T , Schoofs L , et al. Extending the honey bee venome with the antimicrobial peptide apidaecin and a protein resembling wasp antigen 5. Insect Mol Biol 2013; 22:199-210; PMID:23350689; https://doi.org/10.1111/imb.12013
  • Frick M , Muller S , Bantleon F , Huss-Marp J , Lidholm J , Spillner E , Jakob T . rApi m 3 and rApi m 10 improve detection of honey bee sensitization in Hymenoptera venom-allergic patients with double sensitization to honey bee and yellow jacket venom. Allergy 2015; 70:1665-8; PMID:26259841; https://doi.org/10.1111/all.12725
  • Sturm GJ , Hemmer W , Hawranek T , Lang R , Ollert M , Spillner E , Blank S , Bokanovic D , Aberer W . Detection of IgE to recombinant Api m 1 and rVes v 5 is valuable but not sufficient to distinguish bee from wasp venom allergy. J Allergy Clin Immunol 2011; 128:247-8; author reply 8; PMID:21439627; https://doi.org/10.1016/j.jaci.2011.02.021
  • Hofmann SC , Pfender N , Weckesser S , Huss-Marp J , Jakob T . Added value of IgE detection to rApi m 1 and rVes v 5 in patients with Hymenoptera venom allergy. J Allergy Clin Immunol 2011; 127:265-7; PMID:20719373; https://doi.org/10.1016/j.jaci.2010.12.529 10.1016/j.jaci.2010.06.042
  • Christensen L , Larsen J , Monsalve R . Identification of allergens in honeybee venom and confirmation of Api m 10 in immunotherapy products as dertermined by LC-MS/MS. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 2016; 71:71
  • Nelson HS . Allergen immunotherapy: where is it now? J Allergy Clin Immunol 2007; 119:769-79; PMID:17337297; https://doi.org/10.1016/j.jaci.2006.08.026 10.1016/j.jaci.2006.12.332 10.1016/j.jaci.2006.12.613 10.1016/j.jaci.2007.01.036 10.1016/j.jaci.2006.11.589
  • Braren I , Blank S , Seismann H , Deckers S , Ollert M , Grunwald T , Spillner E . Generation of human monoclonal allergen-specific IgE and IgG antibodies from synthetic antibody libraries. Clin Chem 2007; 53:837-44; PMID:17395713; https://doi.org/10.1373/clinchem.2006.078360