Evaluation of two frailty indices, with practical application in a vaccine clinical trial

References

• Searle SD, Mitnitski A, Gahbauer EA, Gill TM, Rockwood K. A standard procedure for creating a frailty index. BMC Geriatr. 2008;8:24. doi:10.1186/1471-2318-8-24.
   PubMedGoogle Scholar
• Mitnitski A, Song X, Skoog I, Broe GA, Cox JL, Grunfeld E, Rockwood, K. Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality. J Am Geriatr Soc. 2005;53:2184–89. doi:10.1111/j.1532-5415.2005.00506.x.
   PubMed Web of Science ®Google Scholar
• Looman WM, Fabbricotti IN, Blom JW, Jansen APD, Lutomski JE, Metzelthin SF, Huijsman, R and on behalf of the TOPICS-MDS Research Consortium. The frail older person does not exist: development of frailty profiles with latent class analysis. BMC Geriatr. 2018;18:84. doi:10.1186/s12877-018-0776-5.
   PubMed Web of Science ®Google Scholar
• Rodríguez-Rodero S, Fernández-Morera JL, Menéndez-Torre E, Calvanese V, Fernández AF, Fraga MF. Aging genetics and aging. Aging Dis. 2011;2:186–95.
   PubMed Web of Science ®Google Scholar
• McElhaney JE, Dutz JP. Better influenza vaccines for older people: what will it take? J Infect Dis. 2008;198:632–34. doi:10.1086/590435.
   PubMed Web of Science ®Google Scholar
• Schmader KE, Johnson GR, Saddier P, Ciarleglio M, Wang WW, Zhang JH, Chan ISF, Yeh -S-S, Levin MJ, Harbecke RM, et al. Effect of a zoster vaccine on herpes zoster-related interference with functional status and health-related quality-of-life measures in older adults. J Am Geriatr Soc. 2010;58:1634–41. doi:10.1111/j.1532-5415.2010.03021.x.
   PubMed Web of Science ®Google Scholar
• Andrew MK, Shinde V, Ye L, Hatchette T, Haguinet F, Dos Santos G, McElhaney JE, Ambrose A, Boivin G, Bowie W, et al. The importance of frailty in the assessment of influenza vaccine effectiveness against influenza-related hospitalization in elderly people. J Infect Dis. 2017;216:405–14. doi:10.1093/infdis/jix282.
   PubMed Web of Science ®Google Scholar
• Curran D, Oostvogels L, Heineman T, Matthews S, McElhaney J, McNeil S, Diez-Domingo J, Lal H, Andrews C, Athan E, et al. Quality of life impact of a recombinant zoster vaccine in adults >/=50 years of age. J Gerontol A Biol Sci Med Sci. 2018. doi:10.1093/gerona/gly150.
   Web of Science ®Google Scholar
• European Medicines Agency: points to consider on frailty: evaluation instruments for baseline characterisation of clinical trial populations. [accessed 2019 Jan 29]. http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2015/12/WC500199243.pdf.
   Google Scholar
• Varghese L, Standaert B, Olivieri A, Curran D. The temporal impact of aging on the burden of herpes zoster. BMC Geriatr. 2017;17:30. doi:10.1186/s12877-017-0420-9.
   PubMed Web of Science ®Google Scholar
• Ryb GE, Dischinger PC, Burch CA, Kerns TJ, Kufera J, Andersen D. Frailty and injury causation. Ann Adv Automot Med. 2012;56:175–81.
   PubMedGoogle Scholar
• Mansur HN, Colugnati FA, Grincenkov FR, Bastos MG. Frailty and quality of life: a cross-sectional study of Brazilian patients with pre-dialysis chronic kidney disease. Health Qual Life Outcomes. 2014;12:27. doi:10.1186/1477-7525-12-27.
   PubMed Web of Science ®Google Scholar
• Masel MC, Graham JE, Reistetter TA, Markides KS, Ottenbacher KJ. Frailty and health related quality of life in older Mexican Americans. Health Qual Life Outcomes. 2009;7:70. doi:10.1186/1477-7525-7-70.
   PubMed Web of Science ®Google Scholar
• Saxton A, Velanovich V. Preoperative frailty and quality of life as predictors of postoperative complications. Ann Surg. 2011;253:1223–29. doi:10.1097/SLA.0b013e318214bce7.
   PubMed Web of Science ®Google Scholar
• Cohen JI. Clinical practice: herpes zoster. N Engl J Med. 2013;369:255–63. doi:10.1056/NEJMcp1302674.
   PubMed Web of Science ®Google Scholar
• Levin MJ, Oxman MN, Zhang JH, Johnson GR, Stanley H, Hayward AR, Caulfield MJ, Irwin MR, Smith JG, Clair J, et al. Varicella-zoster virus-specific immune responses in elderly recipients of a herpes zoster vaccine. J Infect Dis. 2008;197:825–35. doi:10.1086/528696.
   PubMed Web of Science ®Google Scholar
• Weinberg A, Levin MJ. VZV T cell-mediated immunity. Curr Top Microbiol Immunol. 2010;342:341–57. doi:10.1007/82_2010_31.
   PubMed Web of Science ®Google Scholar
• Weinberg A, Lazar AA, Zerbe GO, Hayward AR, Chan IS, Vessey R, Silber JL, MacGregor RR, Chan K, Gershon AA, et al. Influence of age and nature of primary infection on varicella-zoster virus-specific cell-mediated immune responses. J Infect Dis. 2010;201:1024–30. doi:10.1086/651199.
   PubMed Web of Science ®Google Scholar
• Cunningham AL, Lal H, Kovac M, Chlibek R, Hwang SJ, Diez-Domingo J, Godeaux O, Levin MJ, McElhaney JE, Puig-Barberà J, et al. Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older. N Engl J Med. 2016;375:1019–32. doi:10.1056/NEJMoa1603800.
   PubMed Web of Science ®Google Scholar
• Lal H, Cunningham AL, Godeaux O, Chlibek R, Diez-Domingo J, Hwang SJ, Levin MJ, McElhaney JE, Poder A, Puig-Barberà J, et al. Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults. N Engl J Med. 2015;372:2087–96. doi:10.1056/NEJMoa1501184.
   PubMed Web of Science ®Google Scholar
• Schmader KE, Levin MJ, Grupping K, Matthews S, Butuk D, Chen M, Idrissi ME, Fissette LA, Fogarty C, Hartley P, et al. The impact of reactogenicity after the first dose of recombinant zoster vaccine upon the physical functioning and quality of life of older adults: an open phase III trial. J Gerontol A Biol Sci Med Sci. 2018. doi:10.1093/gerona/gly218.
   PubMed Web of Science ®Google Scholar
• Mitnitski AB, Mogilner AJ, Rockwood K. Accumulation of deficits as a proxy measure of aging. ScientificWorldJournal. 2001;1:323–36. doi:10.1100/tsw.2001.58.
   PubMedGoogle Scholar
• Song X, Mitnitski A, Rockwood K. Prevalence and 10-year outcomes of frailty in older adults in relation to deficit accumulation. J Am Geriatr Soc. 2010;58:681–87. doi:10.1111/j.1532-5415.2010.02764.x.
   PubMed Web of Science ®Google Scholar
• Nasreddine ZS, Phillips NA, Bedirian V, Charbonneau S, Whitehead V, Collin I, Cummings, J L., Chertkow, H. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005;53:695–99. doi:10.1111/j.1532-5415.2005.53221.x.
   PubMed Web of Science ®Google Scholar
• Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:M146–56. doi:10.1093/gerona/56.3.m146.
   PubMed Web of Science ®Google Scholar
• Bjorgvinsson T, Kertz SJ, Bigda-Peyton JS, McCoy KL, Aderka IM. Psychometric properties of the CES-D-10 in a psychiatric sample. Assessment. 2013;20:429–36. doi:10.1177/1073191113481998.
   PubMed Web of Science ®Google Scholar
• Ware JE Jr, Kosinski M. SF-36 Physical and mental health summary scales: a manual for users of Version 1. 2nd. Lincoln (RI): Quality Metric Incorporated; 2001.
   Google Scholar
• Kind P. The EuroQL instrument: an index of health-related quality of life. In: Spilker B, editor. Quality of life and pharmacoeconomics in clinical trials. 2nd ed. Philadelphia, New York: Lippincott-Raven Publishers; 1996:191.
   Google Scholar
• Angst F, Aeschlimann A, Stucki G. Smallest detectable and minimal clinically important differences of rehabilitation intervention with their implications for required sample sizes using WOMAC and SF-36 quality of life measurement instruments in patients with osteoarthritis of the lower extremities. Arthritis Rheum. 2001;45:384–91. doi:10.1002/1529-0131(200108)45:4<384::aid-art352>3.0.co;2-0.
   PubMed Web of Science ®Google Scholar
• Walters SJ, Brazier JE. Comparison of the minimally important difference for two health state utility measures: EQ-5D and SF-6D. Qual Life Res. 2005;14:1523–32. doi:10.1007/s11136-004-7713-0.
   PubMed Web of Science ®Google Scholar
• Barker WH, Borisute H, Cox C. A study of the impact of influenza on the functional status of frail older people. Arch Intern Med. 1998;158:645–50. doi:10.1001/archinte.158.6.645.
   PubMedGoogle Scholar
• Zorzoli E, Pica F, Masetti G, Franco E, Volpi A, Gabutti G. Herpes zoster in frail elderly patients: prevalence, impact, management, and preventive strategies. Aging Clin Exp Res. 2018;30:693–702. doi:10.1007/s40520-018-0956-3.
   PubMed Web of Science ®Google Scholar
• Lionis C, Midlov P. Prevention in the elderly: A necessary priority for general practitioners. Eur J Gen Pract. 2017;23:202–07. doi:10.1080/13814788.2017.1350646.
   PubMed Web of Science ®Google Scholar
• Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, Scherr, P A., Wallace, R B. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol. 1994;49:M85–94.
   PubMedGoogle Scholar
• Cesari M, Gambassi G, van Kan GA, Vellas B. The frailty phenotype and the frailty index: different instruments for different purposes. Age Ageing. 2014;43:10–12. doi:10.1093/ageing/aft160.
   PubMed Web of Science ®Google Scholar