Retrospective study of the use of an influenza disease two-tiered classification system to characterize clinical severity in US children

References

• Centers for Disease Control and Prevention. People at high risk of developing flu-related complications. 2018 Jan 23 [accessed 2018 May 21]. https://www.cdc.gov/flu/groups.htm.
   Google Scholar
• Centers for Disease Control and Prevention. What are the benefits of flu vaccination? 2019 Jan 24 [accessed 2019 Nov 21]. https://www.cdc.gov/flu/prevent/vaccine-benefits.htm.
   Google Scholar
• Prymula R, Bergsaker MR, Esposito S, Gothefors L, Man S, Snegova N, Štefkovičova M, Usonis V, Wysocki J, Douha M, et al. Protection against varicella with two doses of combined measles-mumps-rubella-varicella vaccine versus one dose of monovalent varicella vaccine: a multicentre, observer-blind, randomised, controlled trial. Lancet. 2014;383:1313–24. doi:10.1016/S0140-6736(12)61461-5.
   PubMed Web of Science ®Google Scholar
• Ruiz-Palacios GM, Perez-Schael I, Velazquez FR, Abate H, Breuer T, Clemens SC, Cheuvart B, Espinoza F, Gillard P, Innis BL, et al. Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis. N Engl J Med. 2006;354:11–22. doi:10.1056/NEJMoa052434.
   PubMed Web of Science ®Google Scholar
• Jain VK, Rivera L, Zaman K, Espos RA, Sirivichayakul C, Quiambao BP, Rivera-Medina DM, Kerdpanich P, Ceyhan M, Dinleyici EC, et al. Vaccine for prevention of mild and moderate-to-severe influenza in children. N Engl J Med. 2013;369:2481–91. doi:10.1056/NEJMoa1215817.
   PubMed Web of Science ®Google Scholar
• Claeys C, Zaman K, Dbaibo G, Li P, Izu A, Kosalaraksa P, Rivera L, Acosta B, Arroba Basanta ML, Aziz A, et al. Prevention of vaccine-matched and mismatched influenza in children aged 6–35 months: a multinational randomised trial across five influenza seasons. Lancet Child Adolesc Health. 2018;2:338–49. doi:10.1016/S2352-4642(18)30062-2.
   PubMedGoogle Scholar
• Heikkinen T, Silvennoinen H, Heinonen S, Vuorinen T. Clinical and socioeconomic impact of moderate-to-severe versus mild influenza in children. Eur J Clin Microbiol Infect Dis. 2016;35:1107–13. doi:10.1007/s10096-016-2641-9.
   PubMed Web of Science ®Google Scholar
• Streng A, Prifert C, Weissbrich B, Sauerbrei A, Schmidt-Ott R, Liese JG. Subtype-specific clinical presentation, medical treatment and family impact of influenza in children one to five years of age treated in outpatient practices in germany during three post-pandemic years, 2013–2015. Pediatr Infect Dis J. 2018;37(9):861–67. doi:10.1097/INF.0000000000001935.
   PubMed Web of Science ®Google Scholar
• McNutt LA, Wu C, Xue X, Hafner JP. Estimating relative risk in cohort studies and clinical trials of common events. Am J Epidemiol. 2003;157:940–43. doi:10.1093/aje/kwg074.
   PubMed Web of Science ®Google Scholar
• Dawood FS, Chaves SS, Perez A, Reingold A, Meek J, Farley MM, Ryan P, Lynfield R, Morin C, Baumbach J, Emerging Infections Program Network. Complications and associated bacterial coinfections among children hospitalized with seasonal or pandemic influenza, United States, 2003–2010. J Infect Dis. 2014;209:686–94. doi:10.1093/infdis/jit473.
   PubMed Web of Science ®Google Scholar
• Ampofo K, Herbener A, Blaschke AJ, Heyrend C, Poritz M, Korgenski K, Rolfs R, Jain S, Carvalho Mda G, Pimenta FC, et al. Association of 2009 pandemic influenza A (H1N1) infection and increased hospitalization with parapneumonic empyema in children in Utah. Pediatr Infect Dis J. 2010;29:905–09. doi:10.1097/INF.0b013e3181df2c70.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention. Surveillance for pediatric deaths associated with 2009 pandemic influenza A (H1N1) virus infection: United States, April–August 2009. MMWR Morb Mortal Wkly Rep. 2009;58:941–47.
   PubMedGoogle Scholar
• Keren R, Zaoutis TE, Bridges CB, Herrera G, Watson BM, Wheeler AB, Licht DJ, Luan XQ, Coffin SE. Neurological and neuromuscular disease as a risk factor for respiartory failure in children hospitalized with influenza infection. JAMA. 2005;294:2188–94. doi:10.1001/jama.294.17.2188.
   PubMed Web of Science ®Google Scholar
• Malosh RE, Martin ET, Heikkinen T, Brooks WA, Whitley RJ, Monto AS. Efficacy and safety of oseltamivir in children: systematic review and individual patient data meta-analysis of randomized controlled trials. Clin Infect Dis. 2018 May 2;66(10):1492–500. doi:10.1093/cid/cix1040.
   PubMed Web of Science ®Google Scholar
• Garcia MN, Philpott DC, Murray KO, Ontiveros A, Revell PA, Chandramohan L, Munoz FM. Clinical predictors of disease severity during the 2009–2010 A(HIN1) influenza virus pandemic in a paediatric population. Epidmiol Infect. 2015 Oct;143(14):2939–49. doi:10.1017/S0950268815000114.
   PubMed Web of Science ®Google Scholar
• Doyle JD, Campbell AP. Pediatric influenza and illness severity: what is known and what questions remain? Curr Opin Pediatr. 2019;31:119–26. doi:10.1097/MOP.0000000000000721.
   PubMed Web of Science ®Google Scholar
• American Academy of Pediatrics. Influenza. In: Kimberlin D, Brady M, Jackson M, Long S, editors. Red book: 2015 report of the committee on infectious diseases. 30th ed. Elk Grove Village (IL): American Academy of Pediatrics; 2015. p. 481.
   Google Scholar
• Brownstein JS, Kleinman K, Mandl KD. Identifying pediatric age groups for influenza vaccination using a real-time regional surveillance system. Am J Epidemiol. 2005;162(7):686–93. doi:10.1093/aje/kwi257.
   PubMed Web of Science ®Google Scholar
• Mossong J, Hens N, Jit M, Beutels P, Auranen K, Mikolajczyk R, Massari M, Salmaso S, Tomba GS, Wallinga J, et al. Social contacts and mixing patterns relevant to the spread of infectious diseases. PLoS Med. 2008;5(3):e74. doi:10.1371/journal.pmed.0050074.
   PubMed Web of Science ®Google Scholar
• Worby CJ, Chaves SS, Wallinga J, Lipsitch M, Finelli L, Goldstein E. On the relative role of different age groups in influenza epidemics. Epidemics. 2015;13:10–16. doi:10.1016/j.epidem.2015.04.003.
   PubMed Web of Science ®Google Scholar
• Flannery B, Reynolds SB, Blanton L, Santibanez TA, O’Halloran A, Lu P-J, Chen J, Foppa IM, Gargiullo P, Bresee J, et al. Influenza vaccine effectiveness against pediatric deaths: 2010–2014. Pediatrics. 2017;139:e20164244. doi:10.1542/peds.2016-4244.
   PubMed Web of Science ®Google Scholar
• Ambrose CS, Wu X, Caspard H, Belshe RB. Efficacy of live attenuated influenza vaccine against influenza illness in children as a function of illness severity. Vaccine. 2014;32(43):5546–48. doi:10.1016/j.vaccine.2014.07.097.
   PubMed Web of Science ®Google Scholar