Retrospective multicenter matched case–control study on the risk factors for intussusception in infants less than 1 year of age with a special focus on rotavirus vaccines – the German Intussusception Study

References

• Jiang J, Jiang B, Parashar U, Nguyen T, Bines J, Patel MM. Childhood intussusception. PLoS One. 2013;8:e68482. doi:10.1371/journal.pone.0068482.
   PubMed Web of Science ®Google Scholar
• Weiß S, Streng A, von Kries R, Liese J, Wirth S, Jenke AC. Incidence of intussusception in early infancy: a capture-recapture estimate for Germany. Klin Padiatr. 2011;223:419–23. doi:10.1055/s-0031-1279735.
   PubMed Web of Science ®Google Scholar
• Jenke AC, Klaassen-Mielke R, Zilbauer M, Heininger U, Trampisch H, Wirth S. Intussusception: incidence and treatment-insights from the nationwide German surveillance. J Pediatr Gastroenterol Nutr. 2011;52:446–51. doi:10.1097/MPG.0b013e31820e1bec.
   PubMed Web of Science ®Google Scholar
• Samad L, Marven S, El Bashir H, Sutcliffe AG, Cameron JC, Lynn R, Taylor B. Prospective surveillance study of the management of intussusception in UK and Irish infants. Br J Surg. 2012;99:411–15. doi:10.1002/bjs.v99.3.
   PubMed Web of Science ®Google Scholar
• European Centre for Disease Prevention and Control. ECDC expert opinion on rotavirus vaccination in infancy; 2017. https://ecdc.europa.eu/sites/portal/files/documents/rotavirus-vaccination-expert%20opinion-september-2017.pdf.
   Google Scholar
• Lee YW, Yang SI, Kim JM, Kim JY. Clinical features and role of viral isolates from stool samples of intussuception in children. Pediatr Gastroenterol Hepatol Nutr. 2013;16:162–70. doi:10.5223/pghn.2013.16.3.162.
   PubMedGoogle Scholar
• Bines JE, Liem NT, Justice FA, Son TN, Kirkwood CD, de Campo M, Barnett P, Bishop RF, Robins-Browne R, Carlin JB, et al. Risk factors for intussusception in infants in Vietnam and Australia: adenovirus implicated, but not rotavirus. J Pediatr. 2006;149:452–60. doi:10.1016/j.jpeds.2006.04.010.
   PubMed Web of Science ®Google Scholar
• Lappalainen S, Ylitalo S, Arola A, Halkosalo A, Räsänen S, Vesikari T. Simultaneous presence of human herpesvirus 6 and adenovirus infections in intestinal intussusception of young children. Acta Paediatr. 2012;101:663–70. doi:10.1111/apa.2012.101.issue-6.
   PubMed Web of Science ®Google Scholar
• Minney-Smith CA, Levy A, Hodge M, Jacoby P, Williams SH, Carcione D, Roczo-Farkas S, Kirkwood CD, Smith DW. Intussusception is associated with the detection of adenovirus C, enterovirus B and rotavirus in a rotavirus vaccinated population. J Clin Virol. 2014;61:579–84. doi:10.1016/j.jcv.2014.10.018.
   PubMed Web of Science ®Google Scholar
• Arbizu RA, Aljomah G, Kozielski R, Baker SS, Baker RD. Intussusception associated with adenovirus. J Pediatr Gastroenterol Nutr. 2014;59:e41. doi:10.1097/MPG.0b013e3182868971.
   PubMedGoogle Scholar
• Ukarapol N, Khamrin P, Khorana J, Singhavejsakul J, Damrongmanee A, Maneekarn N. Adenovirus infection. J Med Virol. 2016;88:1930–35. doi:10.1002/jmv.v88.11.
   PubMed Web of Science ®Google Scholar
• Asano Y, Yoshikawa T, Suga S, Hata T, Yamazaki T, Yazaki T. Simultaneous occurrence of human herpesvirus 6 infection and intussusception in three infants. Pediatr Infect Dis J. 1991;10:335–37. doi:10.1097/00006454-199104000-00015.
   PubMed Web of Science ®Google Scholar
• Park H, Park S, Hong YJ, Lee SW, Cho M-S. Cytomegalovirus-associated intussusception with florid vascular proliferation in an infant. J Pathol Transl Med. 2015;49:270–73. doi:10.4132/jptm.2015.04.01.
   PubMedGoogle Scholar
• Aminu M, Ameh EA, Geyer A, Esona MD, Taylor MB, Steele AD. Role of astrovirus in intussusception in Nigerian infants. J Trop Pediatr. 2009;55:192–94. doi:10.1093/tropej/fmn101.
   PubMed Web of Science ®Google Scholar
• Moore FO, Berne JD, Slamon NB, Penfil SH, Dunn SP. Intussusception in a child with respiratory syncytial virus. Del Med J. 2006;78:185–87.
   PubMedGoogle Scholar
• Velázquez FR, Luna G, Cedillo R, Torres J, Muñoz O. Natural rotavirus infection is not associated to intussusception in Mexican children. Pediatr Infect Dis J. 2004;23:S173–8. doi:10.1097/01.inf.0000142467.50724.de.
   PubMedGoogle Scholar
• El-Hodhod MA, Nassar MF, Ezz El-Arab S, Ahmed EF. Rotavirus fecal antigen retrieval in infantile intussusception. Eur J Clin Microbiol Infect Dis. 2008;27:879–81. doi:10.1007/s10096-008-0506-6.
   PubMed Web of Science ®Google Scholar
• Chang EJ, Zangwill KM, Lee H, Ward JI, et al. Lack of association between rotavirus infection and intussusception. Pediatr Infect Dis J. 2002;21:97–102. doi:10.1097/00006454-200202000-00003.
   PubMed Web of Science ®Google Scholar
• Ruiz-Palacios GM, Pérez-Schael I, Velázquez FR, Abate H, Breuer T, Clemens SC, Cheuvart B, Espinoza F, Gillard P, Innis BL, et al. Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis. N Engl J Med. 2006;354:11–22. doi:10.1056/NEJMoa052434.
   PubMed Web of Science ®Google Scholar
• Vesikari T, Matson DO, Dennehy P, Van Damme P, Santosham M, Rodriguez Z, Dallas MJ, Heyse JF, Goveia MG, Black SB, et al. Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine. N Engl J Med. 2006;354:23–33. doi:10.1056/NEJMoa052664.
   PubMed Web of Science ®Google Scholar
• Bergman H, Henschke N, Pitan F, Cunliffe, N, Soares‐Weiser, K, et al. Vaccines for preventing rotavirus diarrhoea: vaccines in use. Cochrane Database Syst Rev. 2019 (10). doi: 10.1002/14651858.CD008521.pub5.
   Google Scholar
• Buttery JP, Danchin MH, Lee KJ, Carlin JB, McIntyre PB, Elliott EJ, Booy R, Bines JE. Intussusception following rotavirus vaccine administration: post-marketing surveillance in the national immunization program in Australia. Vaccine. 2011;29:3061–66. doi:10.1016/j.vaccine.2011.01.088.
   PubMed Web of Science ®Google Scholar
• Patel MM, Lopez-Collada VR, Bulhoes MM, De Oliveira LH, Márquez AB, Flannery B, Esparza-Aguilar M, Montenegro Renoiner EI, Luna-Cruz ME, Sato HK, et al. Intussusception risk and health benefits of rotavirus vaccination in Mexico and Brazil. N Engl J Med. 2011;364:2283–92. doi:10.1056/NEJMoa1012952.
   PubMed Web of Science ®Google Scholar
• Velázquez FR, Colindres RE, Grajales C, Hernández MT, Mercadillo MG, Torres FJ, Cervantes-Apolinar M, DeAntonio-Suarez R, Ortega-Barria E, Blum M, et al. Postmarketing surveillance of intussusception following mass introduction of the attenuated human rotavirus vaccine in Mexico. Pediatr Infect Dis J. 2012;31:736–44. doi:10.1097/INF.0b013e318253add3.
   PubMed Web of Science ®Google Scholar
• Yen C, Tate JE, Steiner CA, Cortese MM, Patel MM, Parashar UD. Trends in intussusception hospitalizations among US infants before and after implementation of the rotavirus vaccination program, 2000-2009. J Infect Dis. 2012;206:41–48. doi:10.1093/infdis/jis314.
   PubMed Web of Science ®Google Scholar
• Carlin JB, Macartney KK, Lee KJ, Quinn HE, Buttery J, Lopert R, Bines J, McIntyre PB. Intussusception risk and disease prevention associated with rotavirus vaccines in Australia’s national immunization program. Clin Infect Dis. 2013;57:1427–34. doi:10.1093/cid/cit520.
   PubMed Web of Science ®Google Scholar
• Haber P, Patel M, Pan Y, Baggs J, Haber M, Museru O, Yue X, Lewis P, DeStefano F, Parashar UD, et al. Intussusception after rotavirus vaccines reported to US VAERS, 2006-2012. Pediatrics. 2013;131:1042–49. doi:10.1542/peds.2012-2554.
   PubMed Web of Science ®Google Scholar
• Weintraub ES, Baggs J, Duffy J, Vellozzi C, Belongia EA, Irving S, Klein NP, Glanz JM, Jacobsen SJ, Naleway A, et al. Risk of intussusception after monovalent rotavirus vaccination. N Engl J Med. 2014;370:513–19. doi:10.1056/NEJMoa1311738.
   PubMed Web of Science ®Google Scholar
• Yih WK, Lieu TA, Kulldorff M, Martin D, McMahill-Walraven CN, Platt R, Selvam N, Selvan M, Lee GM, Nguyen M, et al. Intussusception risk after rotavirus vaccination in U.S. Infants N Engl J Med. 2014;370:503–12. doi:10.1056/NEJMoa1303164.
   PubMed Web of Science ®Google Scholar
• Quinn HE, Wood NJ, Cannings KL, Dey A, Wang H, Menzies RI, Moberley S, Reid S, McIntyre PB, Macartney KK, et al. Intussusception after monovalent human rotavirus vaccine in Australia. Pediatr Infect Dis J. 2014;33:959–65. doi:10.1097/INF.0000000000000362.
   PubMed Web of Science ®Google Scholar
• Pérez-Vilar S, Díez-Domingo J, Puig-Barberà J, Gil-Prieto R, Romio S. Intussusception following rotavirus vaccination in the Valencia Region, Spain. Hum Vaccin Immunother. 2015;11:1848–52. doi:10.1080/21645515.2015.1049787.
   PubMed Web of Science ®Google Scholar
• Bauchau V, van Holle L, Mahaux O, Holl K, Sugiyama K, Buyse H. Post-marketing monitoring of intussusception after rotavirus vaccination in Japan. Pharmacoepidemiol Drug Saf. 2015;24:765–70. doi:10.1002/pds.3800.
   PubMed Web of Science ®Google Scholar
• Contopoulos-Ioannidis DG, Halpern MS, Maldonado Y. Trends in hospitalizations for intussusception in California in relationship to the introduction of new rotavirus vaccines, 1985-2010. Pediatr Infect Dis J. 2015;34:712–17. doi:10.1097/INF.0000000000000653.
   PubMed Web of Science ®Google Scholar
• Haber P, Parashar UD, Haber M, DeStefano F. Intussusception after monovalent rotavirus vaccine-United States, vaccine adverse event reporting system (VAERS), 2008-2014. Vaccine. 2015;33:4873–77. doi:10.1016/j.vaccine.2015.07.054.
   PubMed Web of Science ®Google Scholar
• Stowe J, Andrews N, Ladhani S, Miller E. The risk of intussusception following monovalent rotavirus vaccination in England. Vaccine. 2016;34:3684–89. doi:10.1016/j.vaccine.2016.04.050.
   PubMed Web of Science ®Google Scholar
• Leino T, Ollgren J, Strömberg N, Elonsalo U. Evaluation of the intussusception risk after pentavalent rotavirus vaccination in Finnish infants. PLoS One. 2016;11:e0144812. doi:10.1371/journal.pone.0144812.
   PubMed Web of Science ®Google Scholar
• Rotarix - Summary of product characteristics. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000639/WC500054789.pdf.
   Google Scholar
• RotaTeq - summary of product characteristics. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000669/WC500054185.pdf.
   Google Scholar
• Murphy TV, Gargiullo PM, Massoudi MS, Nelson DB, Jumaan AO, Okoro CA, Zanardi LR, Setia S, Fair E, LeBaron CW, et al. Intussusception among infants given an oral rotavirus vaccine. N Engl J Med. 2001;344:564–72. doi:10.1056/NEJM200102223440804.
   PubMed Web of Science ®Google Scholar
• Robert Koch-Institut. Empfehlungen der Ständigen Impfkommission (STIKO) beim Robert Koch-Institut - 2018/2019. Epi Bull; 2018. p. 351.
   Google Scholar
• Dudareva-Vizule S, Koch J, der Heiden M, Oberle D, Keller-Stanislawski B, Wichmann O. Impact of rotavirus vaccination in regions with low and moderate vaccine uptake in Germany. Hum Vaccin Immunother. 2012;8:1407–15. doi:10.4161/hv.21593.
   PubMed Web of Science ®Google Scholar
• Bennett A, Pollock L, Jere KC, Pitzer VE, Lopman B, Parashar U, Everett D, Heyderman RS, Bar-Zeev N, Cunliffe NA, et al. Infrequent transmission of monovalent human rotavirus vaccine virus to household contacts of vaccinated infants in Malawi. J Infect Dis. 2019;219:1730–34. doi:10.1093/infdis/jiz002.
   PubMed Web of Science ®Google Scholar
• Ye S, Whiley DM, Ware RS, Kirkwood CD, Lambert SB, Grimwood K. Multivalent rotavirus vaccine and wild-type rotavirus strain shedding in Australian infants: a birth cohort study. Clin Infect Dis. 2018;66:1411–18. doi:10.1093/cid/cix1022.
   PubMed Web of Science ®Google Scholar
• Rosillon D, Buyse H, Friedland LR, Ng S-P, Velázquez FR, Breuer T. Risk of intussusception after rotavirus vaccination. Pediatr Infect Dis J. 2015;34:763–68. doi:10.1097/INF.0000000000000715.
   PubMed Web of Science ®Google Scholar
• Simonsen L, Morens DM, Elixhauser A, Gerber M, Van Raden M, Blackwelder WC. Effect of rotavirus vaccination programme on trends in admission of infants to hospital for intussusception. The Lancet. 2001;358:1224–29. doi:10.1016/S0140-6736(01)06346-2.
   PubMed Web of Science ®Google Scholar
• Konno T, Suzuki H, Kutsuzawa T, Imai A, Katsushima N, Sakamoto M, Kitaoka S, Tsuboi R, Adachi M. Human rotavirus infection in infants and young children with intussusception. J Med Virol. 1978;2:265–69. doi:10.1002/(ISSN)1096-9071.
   PubMed Web of Science ®Google Scholar
• Burke RM, Tate JE, Dahl RM, Aliabadi, N and Parashar, UD, et al. Does rotavirus vaccination affect longer-term intussusception risk in US infants? J Pediatric Infect Dis Soc. 2019. doi: 10.1093/jpids/piz035.
   PubMed Web of Science ®Google Scholar
• Kurzbart E, Cohen Z, Yerushalmi B, Yulevich A, Newman-Heiman N, Mares AJ. Familial idiopathic intussusception. J Pediatr Surg. 1999;34:493–94. doi:10.1016/S0022-3468(99)90510-9.
   PubMed Web of Science ®Google Scholar
• Papadopoulou F, Efremidis SC. Familial intussusception. J Pediatr Surg. 2002;37:1549–51. doi:10.1053/jpsu.2002.36182.
   PubMed Web of Science ®Google Scholar
• Oshio T, Ogata H, Takano S, Ishibashi H. Familial intussusception. J Pediatr Surg. 2007;42:1509–14. doi:10.1016/j.jpedsurg.2007.04.012.
   PubMed Web of Science ®Google Scholar
• Restivo V, Costantino C, Giorgianni G, Cuccia M, Tramuto F, Corsello G, Casuccio A, Vitale F. Case-control study on intestinal intussusception: implications for anti-rotavirus vaccination. Expert Rev Vaccines. 2018;17:1135–41. doi:10.1080/14760584.2018.1546122.
   PubMed Web of Science ®Google Scholar
• Fotso Kamdem A, Vidal C, Pazart L, Leroux F, Pugin A, Savet C, Sainte-Claire Deville G, Guillemot D, Massol J. A case-control study of risk factors for intussusception among infants in eastern France after the introduction of the rotavirus vaccine. Vaccine. 2019;37:4587–93. doi:10.1016/j.vaccine.2019.02.053.
   PubMed Web of Science ®Google Scholar
• Ong NT, Beasley SW. The leadpoint in intussusception. J Pediatr Surg. 1990;25:640–43. doi:10.1016/0022-3468(90)90353-B.
   PubMed Web of Science ®Google Scholar
• Navarro O, Dugougeat F, Kornecki A, Shuckett B, Alton DJ, Daneman A. The impact of imaging in the management of intussusception owing to pathologic lead points in children. A review of 43 cases. Pediatr Radiol. 2000;30:594–603. doi:10.1007/s002470000261.
   PubMed Web of Science ®Google Scholar
• Lin XK, Xia QZ, Huang XZ, Han YJ, He GR, Zheng N. Clinical characteristics of intussusception secondary to pathologic lead points in children. Pediatr Surg Int. 2017;33:793–97. doi:10.1007/s00383-017-4101-8.
   PubMed Web of Science ®Google Scholar
• Fewell Z, Davey Smith G, Sterne JAC. The impact of residual and unmeasured confounding in epidemiologic studies. Am J Epidemiol. 2007;166:646–55. doi:10.1093/aje/kwm165.
   PubMed Web of Science ®Google Scholar
• Bines JE, Kohl KS, Forster J, Zanardi LR, Davis RL, Hansen J, Murphy TM, Music S, Niu M, Varricchio F, et al. Acute intussusception in infants and children as an adverse event following immunization. Vaccine. 2004;22:569–74. doi:10.1016/j.vaccine.2003.09.016.
   PubMed Web of Science ®Google Scholar
• Voigt M, Rochow N, Schneider KTM, Hagenah HP, Scholz R, Hesse V, Wittwer-Backofen U, Straube S, Olbertz D. Neue Perzentilwerte für die Körpermaße neugeborener Einlinge. Z Geburtshilfe Neonatol. 2014;218:210–17. doi:10.1055/s-00000095.
   PubMedGoogle Scholar
• Petersen CGJ. The yearly immigration of young plaice into the Limfiord from the German sea. Rep Dan Biol Stn. 1896;6:5–84.
   Google Scholar
• Hook EB, Regal RR. Capture-recapture methods in epidemiology: methods and limitations. Epidemiol Rev. 1995;17:243–64. doi:10.1093/oxfordjournals.epirev.a036192.
   PubMed Web of Science ®Google Scholar
• Chapman DG. Some properties of the hypergeometric distribution with applications to zoological sample censuses. Univ California Publ Stat. 1951;1:1131–60.
   Google Scholar
• Lincoln FC. Calculating waterfowl abundance on the basis of banding returns. Circular No. 118. Washington (DC): US Department of Agriculture; 1972. p. 1–4.
   Google Scholar
• Wittes JT. On the bias and estimated variance of Chapman’s two-sample capture-recapture population estimate. Biometrics. 1972;592–97. doi:10.2307/2556173.
   Web of Science ®Google Scholar