Advanced search
Publication Cover
Human Vaccines & Immunotherapeutics Volume 16, 2020 - Issue 10
Submit an article Journal homepage
3,005
Views
48
CrossRef citations to date
0
Altmetric
Commentary

Cytokines and COVID-19: friends or foes?

Mohsen Roknia Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
,
Michael R Hamblinb Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA;c Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Boston, MA, USA
&
Nima Rezaeia Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran;d Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran;e Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, IranCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3836-1827
, MD, PhDORCID Icon
Pages 2363-2365 | Received 21 May 2020, Accepted 17 Jul 2020, Published online: 25 Aug 2020

References

  • Hanaei S, Rezaei N. COVID-19: developing from an outbreak to a pandemic. Archives of Medical Research. 2020. doi:10.1016/j.arcmed.2020.04.021.
  • Saghazadeh A, Rezaei N. Immune-epidemiological parameters of the novel coronavirus–a perspective. Expert Review of Clinical Immunology. 2020;16:465–70. doi:10.1080/1744666X.2020.1750954.
  • Lotfi M, Hamblin MR, Rezaei N. COVID-19: transmission, prevention, and potential therapeutic opportunities. Clinica Chimica Acta. 2020;508:254–66. doi:10.1016/j.cca.2020.05.044.
  • Yazdanpanah F, Hamblin MR, Rezaei N. The immune system and COVID-19: friend or foe? Life Sciences. 2020;256:117900. doi:10.1016/j.lfs.2020.117900.
  • Liu WJ, Zhao M, Liu K, Xu K, Wong G, Tan W, Gao GF. T-cell immunity of SARS-CoV: implications for vaccine development against MERS-CoV. Antiviral Research. 2017;137:82–92. doi:10.1016/j.antiviral.2016.11.006.
  • Xu H, Zhong L, Deng J, Peng J, Dan H, Zeng X, Li T, Chen Q. High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. International Journal of Oral Science. 2020;12:1–5. doi:10.1038/s41368-020-0074-x.
  • Rokni M, Ghasemi V, Tavakoli Z. Immune responses and pathogenesis of SARS‐CoV‐2 during an outbreak in Iran: comparison with SARS and MERS. Reviews in Medical Virology. 2020. doi:10.1002/rmv.2107.
  • He F, Deng Y, Li W. Coronavirus disease 2019 (COVID‐19): what we know? Journal of Medical Virology. 2020;92:719–25. doi:10.1002/jmv.25766.
  • Chen J, Lau YF, Lamirande EW, Paddock CD, Bartlett JH, Zaki SR, Subbarao K. Cellular immune responses to severe acute respiratory syndrome coronavirus (SARS-CoV) infection in senescent BALB/c mice: CD4+ T cells are important in control of SARS-CoV infection. Journal of Virology. 2010;84:1289–301. doi:10.1128/JVI.01281-09.
  • Xu Z, Shi L, Wang Y, Zhang J, Huang L, Zhang C, Liu S, Zhao P, Liu H, Zhu L. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. The Lancet Respiratory Medicine. 2020;8(4):420–22. doi:10.1016/S2213-2600(20)30076-X.
  • Ruan Q, Yang K, Wang W, Jiang L, Song J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive Care Medicine. 2020;1–3.
  • Williams AE, Chambers RC. The mercurial nature of neutrophils: still an enigma in ARDS? American Journal of Physiology-Lung Cellular and Molecular Physiology. 2014;306:L217–L30. doi:10.1152/ajplung.00311.2013.
  • Cameron MJ, Bermejo-Martin JF, Danesh A, Muller MP, Kelvin DJ. Human immunopathogenesis of severe acute respiratory syndrome (SARS). Virus Research. 2008;133:13–19. doi:10.1016/j.virusres.2007.02.014.
  • Channappanavar R, Perlman S editors. Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology. Springer; 2017. Seminars in immunopathology.
  • Min C-K, Cheon S, Ha N-Y, Sohn KM, Kim Y, Aigerim A, Shin HM, Choi J-Y, Inn K-S, Kim J-H. Comparative and kinetic analysis of viral shedding and immunological responses in MERS patients representing a broad spectrum of disease severity. Scientific Reports. 2016;6:1–12. doi:10.1038/srep25359.
  • Golshani M, Saghazadeh A, Rezaei N. SARS-CoV-2–a tough opponent for the immune system. Archives of Medical Research. 2020.
  • Shakoory B, Carcillo JA, Chatham WW, Amdur RL, Zhao H, Dinarello CA, Cron RQ, Opal SM. Interleukin-1 receptor blockade is associated with reduced mortality in sepsis patients with features of the macrophage activation syndrome: re-analysis of a prior Phase III trial. Critical Care Medicine. 2016;44:275. doi:10.1097/CCM.0000000000001402.
  • Saghazadeh A, Rezaei N. Towards treatment planning of COVID-19: rationale and hypothesis for the use of multiple immunosuppressive agents: anti-antibodies, immunoglobulins, and corticosteroids. International Immunopharmacology. 2020;84:1–6. doi:10.1016/j.intimp.2020.106560.
  • Coomes EA, Haghbayan H. Interleukin-6 in COVID-19: a systematic review and meta-analysis. medRxiv. 2020.
  • Richardson P, Griffin I, Tucker C, Smith D, Oechsle O, Phelan A, Stebbing J. Baricitinib as potential treatment for 2019-nCoV acute respiratory disease. The Lancet. 2020;395:e30–e1. doi:10.1016/S0140-6736(20)30304-4.
  • Fardet L, Galicier L, Lambotte O, Marzac C, Aumont C, Chahwan D, Coppo P, Hejblum G. Development and validation of the HScore, a score for the diagnosis of reactive hemophagocytic syndrome. Arthritis & Rheumatology. 2014;66:2613–20. doi:10.1002/art.38690.
  • Wang Y, Chen X, Cao W, Shi Y. Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications. Nature Immunology. 2014;15:1009. doi:10.1038/ni.3002.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.