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Research Paper

Safety and efficacy of rabies immunoglobulin in pediatric patients with suspected exposure

, , , , ORCID Icon &
Pages 2090-2096 | Received 28 Sep 2020, Accepted 16 Nov 2020, Published online: 09 Feb 2021

References

  • Pieracci EG, Pearson CM, Wallace RM, Blanton JD, Whitehouse ER, Ma X, Stauffer K, Chipman RB, Olson V. Vital signs: trends in human rabies deaths and exposures - United States. MMWR Morb Mortal Wkly Rep. 2019;68(23):524–2096. doi:10.15585/mmwr.mm6823e1.
  • Ma X, Monroe BP, Cleaton JM, Orciari LA, Gigante CM, Kirby JD, Chipman RB, Fehlner-Gardiner C, Gutiérrez Cedillo V, Petersen BW, et al. Public veterinary medicine: public health: rabies surveillance in the United States during 2018. J Am Vet Med Assoc. 2020;256(2):195–208. doi:10.2460/javma.256.2.195.
  • Mahadevan A, Suja MS, Mani RS, Shankar SK. Perspectives in diagnosis and treatment of rabies viral encephalitis: insights from pathogenesis. Neurotherapeutics. 2016;13(3):477–92. doi:10.1007/s13311-016-0452-4.
  • Gluska S, Zahavi EE, Chein M, Gradus T, Bauer A, Finke S, Perlson E. Rabies virus hijacks and accelerates the p75NTR retrograde axonal transport machinery. PLoS Pathog. 2014;10(8):e1004348. doi:10.1371/journal.ppat.1004348.
  • Gluska S, Finke S, Perlson E. Receptor-mediated increase in rabies virus axonal transport. Neural Regen Res. 2015;10(6):883–84. doi:10.4103/1673-5374.158337.
  • Fu ZF, Weihe E, Zheng YM, Schäfer MK, Sheng H, Corisdeo S, Rauscher FJ, Koprowski H, Dietzschold B. Differential effects of rabies and borna disease viruses on immediate-early- and late-response gene expression in brain tissues. J Virol. 1993;67(11):6674–81. doi:10.1128/JVI.67.11.6674-6681.1993.
  • Tsiang H. Neuronal function impairment in rabies-infected rat brain. J Gen Virol. 1982;61(Pt 2):277–81. doi:10.1099/0022-1317-61-2-277.
  • Bouzamondo E, Ladogana A, Tsiang H. Alteration of potassium-evoked 5-HT release from virus-infected rat cortical synaptosomes. Neuroreport. 1993;4(5):555–58. doi:10.1097/00001756-199305000-00023.
  • Manning S, Rupprecht C, Fishbein D, Hanlon CA, Lumlertdacha B, Guerra M, Meltzer MI, Dhankhar P, Vaidya SA, Jenkins SR, et al. Human rabies prevention — United States, 2008 recommendations of the advisory committee on immunization practices. MMWR Recommendations Rep. 2008;57:1–28.
  • Madhusudana SN, Ashwin BY, Sudarshan S. Feasibility of reducing rabies immunoglobulin dosage for passive immunization against rabies: results of In vitro and In vivo studies. Hum Vaccin Immunother. 2013;9(9):1914–17. doi:10.4161/hv.25431.
  • Gadekar R, Domple V, Inamdar I, Aswar N, Doibale M. Same dog bite and different outcome in two cases - case report. J Clin Diagn Res. 2014;8:JD01–JD02.
  • Bharti OK, Madhusudana SN, Gaunta PL, Belludi AY. Local infiltration of rabies immunoglobulins without systemic intramuscular administration: an alternative cost effective approach for passive immunization against rabies. Hum Vaccin Immunother. 2016;12(3):837–42. doi:10.1080/21645515.2015.1085142.
  • Ravish H, Krishna C, Kumar P, Siddareddy I, Annadani R. Safety, immunogenicity and clinical efficacy of post exposure prophylaxis in confirmed rabies exposures. Global Vaccines Immunol. 2016;1:56–59. doi:10.15761/GVI.1000116.
  • Wilde H, Sirikawin S, Sabcharoen A, Kingnate D, Tantawichien T, Harischandra PAL, Chaiyabutr N, de Silva DGH, Fernando L, Liyanage JB, et al. Failure of postexposure treatment of rabies in children. Clin Infect Dis. 1996;22(2):228–32. doi:10.1093/clinids/22.2.228.
  • World Heath Organization (WHO). Rabies - Key Facts. 2020. [accessed 2020 Jul 22]. https://www.who.int/news-room/fact-sheets/detail/rabies.
  • Statista. World population by age and region 2019. [accessed 2020 Jul 22]. https://www.statista.com/statistics/265759/world-population-by-age-and-region/.
  • Aoki FY, Rubin ME, Fast MV. Rabies neutralizing antibody in serum of children compared to adults following post-exposure prophylaxis. Biologicals. 1992;20(4):283–87. doi:10.1016/S1045-1056(05)80048-X.
  • Blanton JD, Bowden NY, Eidson M, Wyatt JD, Hanlon CA. Rabies postexposure prophylaxis, New York, 1995-2000. Emerg Infect Dis. 2005;11(12):1921–27. doi:10.3201/eid1112.041278.
  • Dyer JL, Yager P, Orciari L, Greenberg L, Wallace R, Hanlon CA, Blanton JD. Rabies surveillance in the United States during 2013. J Am Vet Med Assoc. 2014;245(10):1111–23. doi:10.2460/javma.245.10.1111.
  • Kedrion Biopharma Inc. KEDRAB [package insert]. Fort Lee (NJ): Kedrion Biopharma Inc.; 2017.
  • Grifols Therapeutics LLC. HYPERRAB [package insert]. Research Triangle Park (NC): Grifols Therapeutics LLC; 2018.
  • Sanofi Pasteur SA. Rabies immune globulin (Human) USP, heat treated Imogam® rabies – HT [package insert]. Marcy L’Etoile (France): Sanofi Pasteur SA; 2018.
  • Rees CA, Hotez PJ, Monuteaux MC, Niescierenko M, Bourgeois FT. Neglected tropical diseases in children: an assessment of gaps in research prioritization. PLoS Negl Trop Dis. 2019;13(1):e0007111. doi:10.1371/journal.pntd.0007111.
  • Loder RT. The demographics of dog bites in the United States. Heliyon. 2019;5(3):e01360. doi:10.1016/j.heliyon.2019.e01360.
  • Rupprecht CE, Briggs D, Brown CM, Franka R, Katz SL, Kerr HD, Lett SM, Levis R, Meltzer MI, Schaffner W, et al. Use of a reduced (4-dose) vaccine schedule for postexposure prophylaxis to prevent human rabies: recommendations of the advisory committee on immunization practices. MMWR Recomm Rep. 2010;59(Rr–2):1–9.
  • Weekly epidemiological record. 2018 Apr 20;93(16):201–20. [accessed 2020 Jun 30]. https://www.who.int/wer/2018/wer9316/en/.
  • Matson MA, Schenker E, Stein M, Zamfirova V, Nguyen H-B, Bergman GE. Safety and efficacy results of simulated post-exposure prophylaxis with human immune globulin (HRIG; KEDRAB) co-administered with active vaccine in healthy subjects: a comparative phase 2/3 trial. Hum Vaccin Immunother. 2020;16(2):452–59. doi:10.1080/21645515.2019.1656967.
  • Kuwert EK, Marcus I, Werner J, Scheiermann N, Hoher PG, Thraenhart O, Hierholzer E, Wiktor TJ, Koprowski H. Post-exposure use of human diploid cell culture rabies vaccine. Dev Biol Stand. 1976;37:273–86.
  • Briggs DJ, Banzhoff A, Nicolay U, Sirikwin S, Dumavibhat B, Tongswas S, Wasi C. Antibody response of patients after postexposure rabies vaccination with small intradermal doses of purified chick embryo cell vaccine or purified Vero cell rabies vaccine. Bull World Health Organ. 2000;78(5):693–98.
  • Moran GJ, Talan DA, Mower W, Newdow M, Ong S, Nakase JY, Pinner RW, Childs JE. Appropriateness of rabies postexposure prophylaxis treatment for animal exposures. Emergency ID net study group. JAMA. 2000;284(8):1001–07. doi:10.1001/jama.284.8.1001.
  • Jerrard DA. The use of rabies immune globulin by emergency physicians. J Emerg Med. 2004;27(1):15–19. doi:10.1016/j.jemermed.2004.02.005.
  • Hwang GS, Rizk E, Bui LN, Iso T, Sartain EI, Tran AT, Swan JT. Adherence to guideline recommendations for human rabies immune globulin patient selection, dosing, timing, and anatomical site of administration in rabies postexposure prophylaxis. Hum Vaccin Immunother. 2020;16(1):51–60. doi:10.1080/21645515.2019.1632680.
  • Fein J, Bogumil D, Upperman JS, Burke RV. Pediatric dog bites: a population-based profile. Inj Prev. 2019;25(4):290–94. doi:10.1136/injuryprev-2017-042621.
  • Dendle C, Looke D. Review article: animal bites: an update for management with a focus on infections. Emerg Med Australas. 2008;20:458–67.
  • Jaindl M, Grünauer J, Platzer P, Endler G, Thallinger C, Leitgeb J, Kovar FM. The management of bite wounds in children–a retrospective analysis at a level I trauma centre. Injury. 2012;43(12):2117–21. doi:10.1016/j.injury.2012.04.016.
  • Bharti OK. Using a modified rabies immunoglobulin protocol in a crisis of unavailability: ethical and practical challenges. Indian J Med Ethics. 2019;4:139–43.
  • Cabasso VJ, Loofbourow JC, Roby RE, Anuskiewicz W. Rabies immune globulin of human origin: preparation and dosage determination in non-exposed volunteer subjects. Bull World Health Organ. 1971;45:303–15.
  • O’Brien KL, Nolan T. The WHO position on rabies immunization - 2018 updates. Vaccine. 2019;37(Suppl1):A85–a87. doi:10.1016/j.vaccine.2018.10.014.
  • Human rabies prevention–United States. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 1999;48(Rr–1):1–21.
  • Venkat H, Matthews J, Narang J, Sunenshine R, Adams LE, Bunko AM, White JR, Levy C, Sylvester T. Human rabies postexposure prophylaxis knowledge and retention among health professionals by using an online continuing education module: Arizona, 2012 to 2015. Pedagogy Health Promot. 2019;5(1):14–23. doi:10.1177/2373379918768329.
  • Gönen I, Soysal A, Topuzoğlu A, Bakir M. Clinical knowledge and attitudes of Turkish physicians toward rabies caused by animal bites. Jpn J Infect Dis. 2011;64:382–90.