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Letter

Epithelioid granulomatous lesions express abundant programmed death ligand-1 (PD-L1): a discussion of adverse events in anti-PD-1 antibody-based cancer immunotherapy

ORCID Icon, , , , , & show all
Pages 1940-1942 | Received 01 Dec 2020, Accepted 21 Dec 2020, Published online: 11 Feb 2021

References

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  • Chorti E, Kanaki T, Zimmer L, Hadaschik E, Ugurel S, Gratsias E, Roesch A, Bonella F, Wessendorf TE, Wälscher J, et al. Drug-induced sarcoidosis-like reaction in adjuvant immunotherapy: increased rate and mimicker of metastasis. Eur J Cancer. 2020;131:18–26. doi:10.1016/j.ejca.2020.02.024.
  • Lazar-Molnar E, Chen B, Sweeney KA, Wang EJ, Liu W, Lin J, Porcelli SA, Almo SC, Nathenson SG, Jacobs WR, et al. Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis. Proc Natl Acad Sci U S A. 2010;107(30):13402–07. doi:10.1073/pnas.1007394107.
  • Molloy A, Laochumroonvorapong P, Kaplan G. Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guerin. J Exp Med. 1994;180:1499–509. doi:10.1084/jem.180.4.1499.
  • Suarez GV, CDC MG, Vecchione MB, Trifone CA, Marín Franco JL, Genoula M, Moraña EJ, Balboa L, Quiroga MF. PD-1/PD-L1 pathway modulates macrophage susceptibility to mycobacterium tuberculosis specific CD8(+) T cell induced death. Sci Rep. 2019;9:187. doi:10.1038/s41598-018-36403-2.

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