The dynamics and association of B and T cell receptor repertoires upon antibody response to hepatitis B vaccination in healthy adults

References

• Nutt SL, Hodgkin PD, Tarlinton DM, Corcoran LM. The generation of antibody-secreting plasma cells. Nat Rev Immunol. 2015;15:160–71. doi:10.1038/nri3795.
   PubMed Web of Science ®Google Scholar
• Shlomchik MJ, Weisel F. Germinal center selection and the development of memory B and plasma cells. Immunol Rev. 2012;247:52–63. doi:10.1111/j.1600-065X.2012.01124.x.
   PubMed Web of Science ®Google Scholar
• Glanville J, Zhai W, Berka J, Telman D, Huerta G, Mehta GR, Ni I, Mei L, Sundar PD, Day GMR, et al. Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire. Proc Natl Acad Sci U S A. 2009;106(48):20216–21. doi:10.1073/pnas.0909775106.
   PubMed Web of Science ®Google Scholar
• Soto C, Bombardi RG, Branchizio A, Kose N, Matta P, Sevy AM, Sinkovits RS, Gilchuk P, Finn JA, Crowe JE, et al. High frequency of shared clonotypes in human B cell receptor repertoires. Nature. 2019;566:398–402. doi:10.1038/s41586-019-0934-8.
   PubMed Web of Science ®Google Scholar
• Galson JD, Pollard AJ, Truck J, Kelly DF. Studying the antibody repertoire after vaccination: practical applications. Trends Immunol. 2014;35:319–31. doi:10.1016/j.it.2014.04.005.
   PubMed Web of Science ®Google Scholar
• Cortina-Ceballos B, Godoy-Lozano EE, Tellez-Sosa J, Ovilla-Munoz M, Samano-Sanchez H, Aguilar-Salgado A, Gomez-Barreto RE, Valdovinos-Torres H, López-Martínez I, Aparicio-Antonio R, et al. Longitudinal analysis of the peripheral B cell repertoire reveals unique effects of immunization with a new influenza virus strain. Genome Med. 2015;7:124. doi:10.1186/s13073-015-0239-y.
   PubMed Web of Science ®Google Scholar
• Galson JD, Truck J, Clutterbuck EA, Fowler A, Cerundolo V, Pollard AJ, Lunter G, Kelly DF. B-cell repertoire dynamics after sequential hepatitis B vaccination and evidence for cross-reactive B-cell activation. Genome Med. 2016;8:68. doi:10.1186/s13073-016-0322-z.
   PubMed Web of Science ®Google Scholar
• Galson JD, Truck J, Fowler A, Clutterbuck EA, Munz M, Cerundolo V, Reinhard C, Van Der Most R, Pollard AJ, Lunter G, et al. Analysis of B cell repertoire dynamics following hepatitis B vaccination in humans, and enrichment of vaccine-specific antibody sequences. EBioMedicine. 2015;2:2070–79. doi:10.1016/j.ebiom.2015.11.034.
   PubMed Web of Science ®Google Scholar
• Jiang N, He J, Weinstein JA, Penland L, Sasaki S, He XS, Dekker CL, Zheng NY, Huang M, Sullivan M, et al. Lineage structure of the human antibody repertoire in response to influenza vaccination. Sci Transl Med. 2013;5:119r–171r. doi:10.1126/scitranslmed.3004794.
   Web of Science ®Google Scholar
• Laserson U, Vigneault F, Gadala-Maria D, Yaari G, Uduman M, Vander HJ, Kelton W, Taek Jung S, Liu Y, Laserson J, et al. High-resolution antibody dynamics of vaccine-induced immune responses. Proc Natl Acad Sci USA. 2014;111:4928–33. doi:10.1073/pnas.1323862111.
   PubMed Web of Science ®Google Scholar
• Miyasaka A, Yoshida Y, Wang T, Takikawa Y. Next-generation sequencing analysis of the human T-cell and B-cell receptor repertoire diversity before and after hepatitis B vaccination. Hum Vaccin Immunother. 2019;15:2738–53. doi:10.1080/21645515.2019.1600987.
   PubMed Web of Science ®Google Scholar
• Vollmers C, Sit RV, Weinstein JA, Dekker CL, Quake SR. Genetic measurement of memory B-cell recall using antibody repertoire sequencing. Proc Natl Acad Sci U S A. 2013;110:13463–68. doi:10.1073/pnas.1312146110.
   PubMed Web of Science ®Google Scholar
• Xu Y, Liu Y, Zhao M, Chen Y, Xie C, Gong M, Deng H, Li X, Sun J, Hou J, et al. Dynamic perturbations of CD4 and CD8 T cell receptor repertoires in chronic hepatitis B patients upon oral antiviral therapy. Front Immunol. 2017;8:1142. doi:10.3389/fimmu.2017.01142.
   PubMed Web of Science ®Google Scholar
• Mamedov IZ, Britanova OV, Zvyagin IV, Turchaninova MA, Bolotin DA, Putintseva EV, Lebedev YB, Chudakov DM. Preparing unbiased T-cell receptor and antibody cDNA libraries for the deep next generation sequencing profiling. Front Immunol. 2013;4:456. doi:10.3389/fimmu.2013.00456.
   PubMed Web of Science ®Google Scholar
• Chen Y, Xu Y, Zhao M, Liu Y, Gong M, Xie C, Wu H, Wang Z. High-throughput T cell receptor sequencing reveals distinct repertoires between tumor and adjacent non-tumor tissues in HBV-associated HCC. Oncoimmunology. 2016;5(10):e1219010. doi:10.1080/2162402X.2016.1219010.
   PubMed Web of Science ®Google Scholar
• Bolotin DA, Poslavsky S, Mitrophanov I, Shugay M, Mamedov IZ, Putintseva EV, Chudakov DM. MiXCR: software for comprehensive adaptive immunity profiling. Nat Methods. 2015;12:380–81. doi:10.1038/nmeth.3364.
   PubMed Web of Science ®Google Scholar
• Krzywinski M, Schein J, Birol I, Connors J, Gascoyne R, Horsman D, Jones SJ, Marra MA. Circos: an information aesthetic for comparative genomics. Genome Res. 2009;19:1639–45. doi:10.1101/gr.092759.109.
   PubMed Web of Science ®Google Scholar
• Sherwood AM, Emerson RO, Scherer D, Habermann N, Buck K, Staffa J, Desmarais C, Halama N, Jaeger D, Schirmacher P, et al. Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue. Cancer Immunol Immunother. 2013;62:1453–61. doi:10.1007/s00262-013-1446-2.
   PubMed Web of Science ®Google Scholar
• Surova E, Jumaa H. The role of BCR isotype in B-cell development and activation. Adv Immunol. 2014;123:101–39.
   PubMed Web of Science ®Google Scholar
• Kometani K, Nakagawa R, Shinnakasu R, Kaji T, Rybouchkin A, Moriyama S, Furukawa K, Koseki H, Takemori T, Kurosaki T, et al. Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation. Immunity. 2013;39:136–47. doi:10.1016/j.immuni.2013.06.011.
   PubMed Web of Science ®Google Scholar
• Giesecke C, Meyer T, Durek P, Maul J, Preiss J, Jacobs J, Thiel A, Radbruch A, Ullrich R, Dörner T, et al. Simultaneous presence of non- and highly mutated Keyhole Limpet Hemocyanin (KLH)-specific plasmablasts early after primary KLH immunization suggests cross-reactive memory B cell activation. J Immunol. 2018;200:3981–92. doi:10.4049/jimmunol.1701728.
   PubMed Web of Science ®Google Scholar
• Wang L, Zhang W, Lin L, Li X, Saksena NK, Wu J, Wang S, Joyce JG, Zhang X, Yang H, et al. A comprehensive analysis of the T and B lymphocytes repertoire shaped by HIV vaccines. Front Immunol. 2018;9:2194. doi:10.3389/fimmu.2018.02194.
   PubMed Web of Science ®Google Scholar
• Ochsenbein AF, Pinschewer DD, Sierro S, Horvath E, Hengartner H, Zinkernagel RM. Protective long-term antibody memory by antigen-driven and T help-dependent differentiation of long-lived memory B cells to short-lived plasma cells independent of secondary lymphoid organs. Proc Natl Acad Sci U S A. 2000;97:13263–68. doi:10.1073/pnas.230417497.
   PubMed Web of Science ®Google Scholar
• Bruce MG, Bruden D, Hurlburt D, Zanis C, Thompson G, Rea L, Toomey M, Townshend-Bulson L, Rudolph K, Bulkow L, et al. Antibody levels and protection after hepatitis B vaccine: results of a 30-year follow-up study and response to a booster dose. J Infect Dis. 2016;214:16–22. doi:10.1093/infdis/jiv748.
   PubMed Web of Science ®Google Scholar
• Zanetti AR, Mariano A, Romano L, D’Amelio R, Chironna M, Coppola RC, Cuccia M, Mangione R, Marrone F, Negrone FS, et al. Long-term immunogenicity of hepatitis B vaccination and policy for booster: an Italian multicentre study. Lancet. 2005;366:1379–84. doi:10.1016/S0140-6736(05)67568-X.
   PubMed Web of Science ®Google Scholar
• Manz RA, Hauser AE, Hiepe F, Radbruch A. Maintenance of serum antibody levels. Annu Rev Immunol. 2005;23:367–86. doi:10.1146/annurev.immunol.23.021704.115723.
   PubMed Web of Science ®Google Scholar
• Fairfax KA, Kallies A, Nutt SL, Tarlinton DM. Plasma cell development: from B-cell subsets to long-term survival niches. Semin Immunol. 2008;20:49–58. doi:10.1016/j.smim.2007.12.002.
   PubMed Web of Science ®Google Scholar
• Galson JD, Truck J, Fowler A, Munz M, Cerundolo V, Pollard AJ, Lunter G, Kelly DF. In-depth assessment of within-individual and inter-individual variation in the B cell receptor repertoire. Front Immunol. 2015;6:531. doi:10.3389/fimmu.2015.00531.
   PubMed Web of Science ®Google Scholar
• Ma L, Wang X, Bi X, Yang J, Shi B, He X, Ma R, Ma Q, Yao X. Characteristics peripheral blood IgG and IgM heavy chain complementarity determining region 3 repertoire before and after immunization with recombinant HBV vaccine. PLoS One. 2017;12:e170479.
   PubMed Web of Science ®Google Scholar
• Tajiri K, Ozawa T, Jin A, Tokimitsu Y, Minemura M, Kishi H, Sugiyama T, Muraguchi A. Analysis of the epitope and neutralizing capacity of human monoclonal antibodies induced by hepatitis B vaccine. Antiviral Res. 2010;87:40–49. doi:10.1016/j.antiviral.2010.04.006.
   PubMed Web of Science ®Google Scholar
• Merkenschlager J, Ploquin MJ, Eksmond U, Andargachew R, Thorborn G, Filby A, Pepper M, Evavold B, Kassiotis G. Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response. Nat Commun. 2016;7:10281. doi:10.1038/ncomms10281.
   PubMed Web of Science ®Google Scholar
• Vidan-Jeras B, Brinovec V, Jurca B, Stezinar SL, Jeras M, Bohinjec M. The contribution of HLA-Class II antigens in humoral non-response and delayed response to HBsAg vaccination. Pflugers Arch. 2000;440:R188–R189. doi:10.1007/s004240000059.
   Web of Science ®Google Scholar
• Sakai A, Noguchi E, Fukushima T, Tagawa M, Iwabuchi A, Kita M, Kakisaka K, Miyasaka A, Takikawa Y, Sumazaki R, et al. Identification of amino acids in antigen-binding site of class II HLA proteins independently associated with hepatitis B vaccine response. Vaccine. 2017;35:703–10. doi:10.1016/j.vaccine.2016.08.068.
   PubMed Web of Science ®Google Scholar
• Nishida N, Sugiyama M, Sawai H, Nishina S, Sakai A, Ohashi J, Khor SS, Kakisaka K, Tsuchiura T, Hino K, et al. Key HLA-DRB1-DQB1 haplotypes and role of the BTNL2 gene for response to a hepatitis B vaccine. Hepatology. 2018;68:848–58. doi:10.1002/hep.29876.
   PubMed Web of Science ®Google Scholar