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Public Health – Mini-Review

Burden of vaccine-preventable diseases, trends in vaccine coverage and current challenges in the implementation of the expanded program on immunization: A situation analysis of Cameroon

ORCID Icon, , , &
Article: 1939620 | Received 25 Feb 2021, Accepted 02 Jun 2021, Published online: 01 Jul 2021

References

  • Plotkin S. History of vaccination. Proc Nat Acad Sci. 2014;111(34):12283–10. doi:10.1073/pnas.1400472111.
  • Stern AM, Markel H. The history of vaccines and immunization: familiar patterns, new challenges. Health Aff. 2005;24(3):611–21. doi:10.1377/hlthaff.24.3.611.
  • Centers for Disease Control and Prevention (CDC). Ten great public health achievements--worldwide, 2001-2010. MMWR Morb Mortal Wkly Rep. 2011;60(24):814–18. https://www.ncbi.nlm.nih.gov/pubmed/21697806.
  • Machingaidze S, Wiysonge CS, Hussey GD. Strengthening the expanded programme on immunization in Africa: looking beyond 2015. PLoS Med. 2013;10(3):e1001405. doi:10.1371/journal.pmed.1001405.
  • WHO. National programmes and systems. 2016 [cited 2020 Apr 25]; https://www.who.int/immunization/programmes_systems/en/
  • WHO. WHO department on immunization, vaccines and biologicals; 2020 [accessed 2020 Apr 25]. https://www.who.int/immunization/en/
  • Ebile Akoh W, Ateudjieu J, Nouetchognou JS, Yakum MN, Djouma Nembot F, Nafack Sonkeng S, Saah Fopa M, Watcho P. The expanded program on immunization service delivery in the Dschang health district, west region of Cameroon: a cross sectional survey. BMC Public Health. 2016;16(1):801. doi:10.1186/s12889-016-3429-7.
  • Kwedi Nolna S, Bonono C-R, Nsangou Moncher M, Bindé T, Nolna D, Ongolo Zogo P. Factors influencing the performance of routine immunization in urban areas: a comparative case study of two cities in Cameroon: douala and Yaoundé. Vaccine. 2018;36(49):7549–55. doi:10.1016/j.vaccine.2018.10.048.
  • Russo G, Miglietta A, Pezzotti P, Biguioh RM, Mayaka GB, Sobze MS, Stefanelli P, Vullo V, Rezza G. Vaccine coverage and determinants of incomplete vaccination in children aged 12–23 months in Dschang, West Region, Cameroon: a cross-sectional survey during a polio outbreak. BMC Public Health. 2015;15(1). doi:10.1186/s12889-015-2000-2.
  • Ministry of public health Cameroon. Comprehensive multi-year plan 2007-2011 of the expanded programme on immunisation; 2006. https://www.gavi.org/sites/default/files/document/cmyps-cameroon-2007-2011pdf.pdf
  • WHO. The RED strategy; 2018 [accessed 2020 May 1]. https://www.who.int/immunization/programmes_systems/service_delivery/red/en/
  • Ryman T, Macauley R, Nshimirimana D, Taylor P, Shimp L, Wilkins K. Reaching every district (RED) approach to strengthen routine immunization services: evaluation in the African region, 2005. J Public Health. 2010;32(1):18–25. doi:10.1093/pubmed/fdp048.
  • Cutts FT. Advances and challenges for the expanded programme on immunization. Br Med Bull. 1998;54(2):445–61. doi:10.1093/oxfordjournals.bmb.a011700.
  • WHO. WHO department on Immunization, Vaccines and Biologicals; 2020 [accessed 2020 Apr 28]. https://www.who.int/immunization/en/
  • Immunization programme. [accessed 2020 Jun 7]. https://www.unicef.org/immunization
  • Parpia AS, Skrip LA, Nsoesie EO, Ngwa MC, Abah Abah AS, Galvani AP, Ndeffo-Mbah ML. Spatio-temporal dynamics of measles outbreaks in Cameroon. Ann Epidemiol. 2020;42:64–72.e3. doi:10.1016/j.annepidem.2019.10.007.
  • Patel MK, Orenstein WA. Classification of global measles cases in 2013–17 as due to policy or vaccination failure: a retrospective review of global surveillance data. The Lancet Global Health. 2019;7(3):e313–20. doi:10.1016/s2214-109x(18)30492-3.
  • Wahl B, O’Brien KL, Greenbaum A, Majumder A, Liu L, Chu Y, Lukšić I, Nair H, McAllister DA, Campbell H, et al. Burden of streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national estimates for 2000–15. The Lancet Global Health. 2018;6(7):e744–57. doi:10.1016/s2214-109x(18)30247-x.
  • WHO. Immunization coverage; 2020 [accessed 2020 Nov 16]. https://www.who.int/immunization/monitoring_surveillance/routine/coverage/en/index4.html
  • Cummings DAT, Moss WJ, Long K, Wiysonge CS, Muluh TJ, Kollo B, Nomo E, Wolfe ND, Burke DS. Improved measles surveillance in Cameroon reveals two major dynamic patterns of incidence. Int J Infect Dis. 2006;10(2):148–55. doi:10.1016/j.ijid.2004.10.010.
  • Nguefack F. Morbidity and mortality from measles in Cameroonian children: implications for measles control. Open Area Stud J. 2011;4(1):7–13. doi:10.2174/1874914301104010007.
  • WHO. WHO vaccine-preventable diseases: monitoring system. 2019 global summary. WHO10-December-2019. [accessed 2020 Mar 5]. https://apps.who.int/immunization_monitoring/globalsummary/coverages?c=CMR
  • WHO, World Health Organization. WHO | immunization country profile. [accessed 2020 Dec 22]. https://apps.who.int/immunization_monitoring/globalsummary/estimates?c=CMR
  • Luquero FJ, Pham-Orsetti H, Cummings DAT, Ngaunji PE, Nimpa M, Fermon F, Ngoe N, Sosler S, Strebel P, Grais RF. A long-lasting measles epidemic in Maroua, Cameroon 2008–2009: mass vaccination as response to the epidemic. J Infect Dis. 2011;204(suppl_1):S243–51. doi:10.1093/infdis/jir093.
  • Sume GE, Fouda AAB, Kobela M, Nguelé S, Emah I, Atem P. A locally initiated and executed measles outbreak response immunization campaign in the nylon health district, Douala Cameroon 2011. BMC Res Notes. 2013;6:100. doi:10.1186/1756-0500-6-100.
  • Njim T, Agyingi K, Aminde LN, Atunji EF. Trend in mortality from a recent measles outbreak in Cameroon: a retrospective analysis of 223 measles cases in the Benakuma Health District. Pan Afr Med J. 2016;23:135. doi:10.11604/pamj.2016.23.135.8630.
  • Rudan I. Epidemiology and etiology of childhood pneumonia. Bull World Health Organ. 2008;86(5):408–16. doi:10.2471/blt.07.048769.
  • Libwea JN, Kingue SRB, Ashukem NT, Kobela M, Boula A, Sinata K-S, Ndombo PK, Boum Y. Assessing the causes of under-five mortality and proportion associated with pneumococcal diseases in Cameroon. A case-finding retrospective observational study: 2006–2012. PLOS ONE. 2019;14(4):e0212939. doi:10.1371/journal.pone.0212939.
  • Ayieko P, Griffiths UK, Ndiritu M, Moisi J, Mugoya IK, Kamau T, English M, Scott JAG. Assessment of health benefits and cost-effectiveness of 10-valent and 13-valent pneumococcal conjugate vaccination in Kenyan children. PLoS One. 2013;8:e67324. doi:10.1371/journal.pone.0067324.
  • Massenet D, Tapindjin-Gake M. Positive effect of the introduction of Haemophilus influenzae type b vaccination in the expanded program on immunization in Cameroon. Vaccine. 2010;28(39):6404–05. doi:10.1016/j.vaccine.2010.07.033.
  • Njuma Libwea J, Gröndahl-Yli-Hannuksela K, Kobela M, Toropainen M, Nyholm O, Ndombo PK, Koulla-Shiro S, Nohynek H, Nuorti JP, Vuopio J, et al. Prevalence of pneumococcal nasopharyngeal colonization and serotypes circulating in Cameroonian children after the 13-valent pneumococcal conjugate vaccine introduction. Int J Infect Dis. 2020;98:113–20. doi:10.1016/j.ijid.2020.06.048.
  • Wallén B. Pneumonia among children less than 5 years in Cameroon following introduction of a 13-valent pneumococcal conjugate vaccine;2014.
  • Tazinya AA, Halle-Ekane GE, Mbuagbaw LT, Abanda M, Atashili J, Obama MT. Risk factors for acute respiratory infections in children under five years attending the Bamenda Regional Hospital in Cameroon. BMC Pulm Med. 2018;18(1):7. doi:10.1186/s12890-018-0579-7.
  • Seidu -A-A, Dickson KS, Ahinkorah BO, Amu H, Darteh EKM, Kumi-Kyereme A. Prevalence and determinants of acute lower respiratory Infections among children under-five years in sub–Saharan Africa: evidence from demographic and health surveys. SSM - Pop Health. 2019;8:100443. doi:10.1016/j.ssmph.2019.100443.
  • Tchatchouang S, Nzouankeu A, Kenmoe S, Ngando L, Penlap V, Fonkoua M-C, Pefura-Yone E-W, Njouom R. Bacterial aetiologies of lower respiratory tract infections among adults in Yaoundé, Cameroon. Biomed Res Int. 2019;2019:4834396. doi:10.1155/2019/4834396.
  • Koulla-Shiro S, Kuaban C, Bélec L. Microbial etiology of acute community-acquired pneumonia in adult hospitalized patients in Yaounde-Cameroon. Clin Microbiol Infect. 1997;3(2):180–86. doi:10.1111/j.1469-0691.1997.tb00595.x.
  • Bigna JJ, Amougou MA, Asangbeh SL, Kenne AM, Noumegni SRN, Ngo-Malabo ET, Noubiap JJ. Seroprevalence of hepatitis B virus infection in Cameroon: a systematic review and meta-analysis. BMJ Open. 2017;7(6):e015298. doi:10.1136/bmjopen-2016-015298.
  • Joseph F, Rodrigue KW, Serges T, Salomon NP, Christian TN, Carlos TTM, Samuel F, Anne-Esther -N-N, Colizzi V, Celine NN. Hepatitis B infection and risk factors among children living with HIV in Yaounde, Cameroon: an integrated management. BMC Pediatr. 2019;19(1):366. doi:10.1186/s12887-019-1750-x.
  • Njouom R, Tejiokem M. Épidémiologie des hépatites virales b, c, et delta au Cameroun: analyse des échantillons de l’enquête démographique de santé 2011. ANRS INSERM; 2015. https://www.anrs-cameroun.org/wp-content/uploads/2018/01/ANRS12289-Njouom-Oct-2016_0.pdf .
  • Bilounga Ndongo C, Eteki L, Siedner M, Mbaye R, Chen J, Ntone R, Donfack O, Bongwong B, Essaka Evoue R, Zeh F, et al. Prevalence and vaccination coverage of Hepatitis B among healthcare workers in Cameroon: a national seroprevalence survey. J Viral Hepat. 2018;25(12):1582–87. doi:10.1111/jvh.12974.
  • Fomulu NJ, Morfaw FLI, Torimiro JN, Nana P, Koh MV, William T. Prevalence, correlates and pattern of Hepatitis B among antenatal clinic attenders in Yaounde-Cameroon: is perinatal transmission of HBV neglected in Cameroon? BMC Pregnancy Childbirth. 2013;13(1):158. doi:10.1186/1471-2393-13-158.
  • Nelson NP, Easterbrook PJ, McMahon BJ. Epidemiology of Hepatitis B virus infection and impact of vaccination on disease. Clin Liver Dis. 2016;20(4):607–28. doi:10.1016/j.cld.2016.06.006.
  • Tsague MK, Fotio AL, Bomgning CLK, Nguefack-Tsague G, Fopa F, Nguelefack TB. Prevalence of viral and non-viral hepatitis in Menoua Division, West Region, Cameroon: a retrospective hospital-based study. Pan Afr Med J. 2019;32:212. doi:10.11604/pamj.2019.32.212.16495.
  • Meriki HD, Tufon KA, Anong DN, Tony NJ, Kwenti TE, Bolimo AF, Kouanou YS, Nkuo-Akenji T, Bansal GP. Vaccine uptake and immune responses to HBV infection amongst vaccinated and non-vaccinated healthcare workers, household and sexual contacts to chronically infected HBV individuals in the South West Region of Cameroon. PLOS ONE. 2018;13(7):e0200157. doi:10.1371/journal.pone.0200157.
  • Tatsilong HOP, Noubiap JJN, Nansseu JRN, Aminde LN, Bigna JJR, Ndze VN, Moyou RS. Hepatitis B infection awareness, vaccine perceptions and uptake, and serological profile of a group of health care workers in Yaoundé, Cameroon. BMC Public Health. 2016;15:706. doi:10.1186/s12889-016-3388-z.
  • Ngwa CH, Ngoh EA, Cumber SN. Assessment of the knowledge, attitude and practice of health care workers in Fako Division on post exposure prophylaxis to blood borne viruses: a hospital based cross-sectional study. Pan Afr Med J. 2018;31:108. doi:10.11604/pamj.2018.31.108.15658.
  • Kyu HH, Mumford JE, Stanaway JD, Barber RM, Hancock JR, Vos T, Murray CJL, Naghavi M. Mortality from tetanus between 1990 and 2015: findings from the global burden of disease study 2015. BMC Public Health. 2017;17:179. doi:10.1186/s12889-017-4111-4.
  • Mosser JF, Gagne-Maynard W, Rao PC, Osgood-Zimmerman A, Fullman N, Graetz N, Burstein R, Updike RL, Liu PY, Ray SE, et al. Mapping diphtheria-pertussis-tetanus vaccine coverage in Africa, 2000–2016: a spatial and temporal modelling study. Lancet. 2019;393(10183):1843–55. doi:10.1016/S0140-6736(19)30226-0.
  • WHO. World Health Organization. Validation of maternal and neonatal tetanus elimination in Cameroon, 2012 = Validation de l’élimination du tétanos maternel et néonatal au Cameroun, 2012. WHO; 2013. https://apps.who.int/iris/handle/10665/242144
  • Center TNCB. The national catholic bioethics center. Moral reflections on vaccines prepared from cells derived from aborted human fetuses. Natl Cathol Bioeth Q. 2006;6(3):541–50. doi:10.5840/ncbq20066334.
  • Feldman-Savelsberg P, Ndonko FT, Schmidt-Ehry B. Sterilizing vaccines or the politics of the womb: retrospective study of a rumor in Cameroon. Med Anthropol Q. 2000;14:159–79. https://anthrosource.onlinelibrary.wiley.com/doi/abs/10.1525/maq.2000.14.2.159?casa_token=yUkU__MoQDEAAAAA:4G2uFS3V1Dr_-NatjvxLUkfaH7EIDTrEs9M2sInRztuYpin-bOlpTADxUU1WsgRzPVegQsHPlMtKVm5G .
  • Selove R, Foster M, Mack R, Sanderson M, Hull PC. Using an implementation research framework to identify potential facilitators and barriers of an intervention to increase HPV vaccine uptake. J Public Health Manag Pract. 2017;23(3):e1–9. doi:10.1097/PHH.0000000000000367.
  • Cameroon TL. John Benjamins publishing; 1982. https://play.google.com/store/books/details?id=8Y1nLo6hvPAC
  • Nda’chi Deffo R, Fomba Kamga B. Do the dynamics of vaccine programs improve the full immunization of children under the age of five in Cameroon? BMC Health Serv Res. 2020;20(1):953. doi:10.1186/s12913-020-05745-x.
  • Karafillakis E, Simas C, Jarrett C, Verger P, Peretti-Watel P, Dib F, De Angelis S, Takacs J, Ali KA, Pastore Celentano L, et al. HPV vaccination in a context of public mistrust and uncertainty: a systematic literature review of determinants of HPV vaccine hesitancy in Europe. Hum Vaccin Immunother. 2019;15(7–8):1615–27. doi:10.1080/21645515.2018.1564436.
  • Mupandawana ET, Cross R. Attitudes towards human papillomavirus vaccination among African parents in a city in the north of England: a qualitative study. Reprod Health. 2016;13(1):97. doi:10.1186/s12978-016-0209-x.
  • Kindzeka ME. Cameroon: millions of girls at risk for cervical cancer as parents reject HPV vaccination. [accessed 2020 Dec 27]. https://www.voanews.com/africa/cameroon-millions-girls-risk-cervical-cancer-parents-reject-hpv-vaccination
  • Jegede AS. What led to the Nigerian boycott of the polio vaccination campaign? PLoS Med. 2007;4(3):e73. doi:10.1371/journal.pmed.0040073.
  • Bangura JB, Xiao S, Qiu D, Ouyang F, Chen L. Barriers to childhood immunization in sub-Saharan Africa: a systematic review. BMC Public Health. 2020;20(1):1108. doi:10.1186/s12889-020-09169-4.
  • Tefera YA, Wagner AL, Mekonen EB, Carlson BF, Boulton ML. Predictors and barriers to full vaccination among children in Ethiopia. Vaccines (Basel). 2018;6. http://dx.doi.org/10.3390/vaccines6020022 .
  • Lim SS, Stein DB, Charrow A, Murray CJL. Tracking progress towards universal childhood immunisation and the impact of global initiatives: a systematic analysis of three-dose diphtheria, tetanus, and pertussis immunisation coverage. Lancet. 2008;372:2031–46. http://www.sciencedirect.com/science/article/pii/S0140673608618693 .
  • Ateudjieu J, Kenfack B, Nkontchou BW, Demanou M. Program on immunization and cold chain monitoring: the status in eight health districts in Cameroon. BMC Res Notes. 2013;6(1):101. doi:10.1186/1756-0500-6-101.
  • Fisher-Borne M, Preiss AJ, Black M, Roberts K, Saslow D. Early outcomes of a multilevel human papillomavirus vaccination pilot intervention in federally qualified health centers. Acad Pediatr. 2018;18(2):S79–84. doi:10.1016/j.acap.2017.11.001.
  • Wallace A, Ryman T, Mihigo R, Ndoutabe M, Tounkara B, Grant G, Anya B, Kiawi EC, Kone S, Tesfaye H, et al. Strengthening evidence-based planning of integrated health service delivery through local measures of health intervention delivery times. J Infect Dis. 2012;205(Suppl 1):S40–8. doi:10.1093/infdis/jir775.
  • Hamid H, Mallhi TH, Naseer MS, Younas I, Rashid MA, Pervaiz A, Ain NU. The COVID-19 pandemic threatens the expanded program on Immunization: recommendations for sustaining vaccination goals. Drugs Ther Perspect. 2020:1–3. doi:10.1007/s40267-020-00774-2.
  • Oyaro K. Taking health services to remote areas. Africa Renewal. 2017;30(3):22–23. [accessed 2021 May 6]. https://www.un.org/africarenewal/magazine/december-2016-march-2017/taking-health-services-remote-areas .
  • Libwea JN, Kobela M, Ollgren J, Emah I, Tchio R, Nohynek H. Predictors to parental knowledge about childhood immunisation/EPI vaccines in two health districts in Cameroon prior to the introduction of 13-valent Pneumococcal Conjugate Vaccines (PCV-13). Pan Afr Med J. 2014;17. doi:10.11604/pamj.2014.17.187.1911.
  • Oyo-Ita A, Wiysonge CS, Oringanje C, Nwachukwu CE, Oduwole O, Meremikwu MM. Interventions for improving coverage of childhood immunisation in low- and middle-income countries. Cochrane Database Syst Rev. 2016;7:CD008145. doi:10.1002/14651858.CD008145.pub3.
  • Ngo NV, Pemunta NV, Muluh NE, Adedze M, Basil N, Agwale S. Armed conflict, a neglected determinant of childhood vaccination: some children are left behind. Hum Vaccin Immunother. 2020;16(6):1454–63. doi:10.1080/21645515.2019.1688043.
  • Metuge A, Omam L-A, Jarman E, Njomo EO. Humanitarian led community-based surveillance: case study in Ekondo-titi, Cameroon. Confl Health. 2021;15:17. doi:10.1186/s13031-021-00354-9.
  • Adepoju P. Hospital attack in anglophone Cameroon kills four patients. Lancet. 2019;393:731. doi:10.1016/S0140-6736(19)30407-6.
  • Saso A, Skirrow H, Kampmann B. Impact of COVID-19 on immunization services for maternal and infant vaccines: results of a survey conducted by imprint-the immunising pregnant women and infants network. Vaccines (Basel). 2020;8. doi:10.3390/vaccines8030556.