1,869
Views
1
CrossRef citations to date
0
Altmetric
Flu – Research Paper

The protective effect of a combination of human intracellular and extracellular antibodies against the highly pathogenic avian influenza H5N1 virus

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon
Article: 2035118 | Received 27 Aug 2021, Accepted 16 Jan 2022, Published online: 03 Mar 2022

References

  • Andrade CR, Ibiapina Cda C, Champs NS, Toledo Junior AC, Picinin IF. Avian influenza: the threat of the 21st century. J Bras Pneumol. 2009;35:5.
  • Kilbourne ED. Influenza pandemics of the 20th century. Emerg Infect Dis. 2006;12(1):1. doi:10.3201/eid1201.051254.
  • Uyeki TM. Human infection with highly pathogenic avian influenza A (H5N1) virus: review of clinical issues. Clin Infect Dis. 2009;49(2):2. doi:10.1086/600035.
  • Nicholls H. Pandemic influenza: the inside story. PLoS Biol. 2006;4(2):2. doi:10.1371/journal.pbio.0040050.
  • Gregg MB, Hinman AR, Craven RB. The Russian flu. Its history and implications for this year’s influenza season. JAMA. 1978;240:21. doi:10.1001/jama.1978.03290210042022.
  • Gao R, Cao B, Hu Y, Feng Z, Wang D, Hu W, Chen J, Jie Z, Qiu H, Xu K, et al. Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med. 2013;368:20. doi:10.1056/NEJMoa1304459.
  • Wang H, Feng Z, Shu Y, Yu H, Zhou L, Zu R, Huai Y, Dong J, Bao C, Wen L, et al. Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China. Lancet. 2008;371:9622. doi:10.1016/S0140-6736(08)60493-6.
  • Doerr HW, Varwig D, Allwinn R, Cinatl J. Will the next human influenza pandemic be caused by the virus of the avian flu A/H5N1? Arguments pro and counter. Med Microbiol Immunol. 2006;195:2. doi:10.1007/s00430-005-0008-4.
  • De Clercq E, Neyts J. Avian influenza A (H5N1) infection: targets and strategies for chemotherapeutic intervention. Trends Pharmacol Sci. 2007;28:6.
  • Russell CJ, Webster RG. The genesis of a pandemic influenza virus. Cell. 2005;123:3. doi:10.1016/j.cell.2005.10.019.
  • Subbarao K, Murphy BR, Fauci AS. Development of effective vaccines against pandemic influenza. Immunity. 2006;24(1):1. doi:10.1016/j.immuni.2005.12.005.
  • Zhang X, Qi X, Zhang Q, Zeng X, Shi Z, Jin Q, Zhan F, Xu Y, Liu Z, Feng Z, et al. Human 4F5 single-chain Fv antibody recognizing a conserved HA1 epitope has broad neutralizing potency against H5N1 influenza A viruses of different clades. Antiviral Res. 2013;99:2.
  • Baltimore D. Gene therapy. Intracellular immunization. Nature. 1988;335(6189):6189. doi:10.1038/335395a0.
  • Zhang T, Wang TC, Zhao PS, Liang M, Gao YW, Yang ST, Qin C, Wang CY, Xia XZ. Antisense oligonucleotides targeting the RNA binding region of the NP gene inhibit replication of highly pathogenic avian influenza virus H5N1. Int Immunopharmacol. 2011;11:12. doi:10.1016/j.intimp.2011.08.019.
  • Nawtaisong P, Keith J, Fraser T, Balaraman V, Kolokoltsov A, Davey RA, Higgs S, Mohammed A, Rongsriyam Y, Komalamisra N, et al. Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome. Virol J. 2009;6(1). doi:10.1186/1743-422X-6-73.
  • Zhou K, He H, Wu Y, Duan M. RNA interference of avian influenza virus H5N1 by inhibiting viral mRNA with siRNA expression plasmids. J Biotechnol. 2008;135(2):2. doi:10.1016/j.jbiotec.2008.03.007.
  • Marasco WA. Intrabodies: turning the humoral immune system outside in for intracellular immunization. Gene Ther. 1997;4:1. doi:10.1038/sj.gt.3300346.
  • Niwa H, Yamamura K, Miyazaki J. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene. 1991;108:2.
  • Brondyk B. pCI and pSI Mammalian expression vectors. Promega Note. 1994;49:7-11.
  • Rader C, Popkov M, Neves JA, Barbas CF 3rd. Integrin alpha(v)beta3 targeted therapy for Kaposi’s sarcoma with an in vitro evolved antibody. FASEB J. 2002;16:14. doi:10.1096/fj.02-0281fje.
  • Reed LJ, Muench HA. A simple method of estimating fifty percent endpoints. Am J Hyg. 1938;27:493–12.
  • Krah DL. A simplified multiwell plate assay for the measurement of hepatitis A virus infectivity. Biologicals. 1991;19:3. doi:10.1016/1045-1056(91)90039-M.
  • Prausnitz MR, Mikszta JA, Cormier M, and Andrianov AK. Microneedle-based vaccines. Curr Top Microbiol Immunol. 2009;333:369-93.
  • Sui J, Hwang WC, Perez S, Wei G, Aird D, Chen LM, Santelli E, Stec B, Cadwell G, Ali M, et al. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat Struct Mol Biol. 2009;16:3. doi:10.1038/nsmb.1566.
  • Oh HL, Akerstrom S, Shen S, Bereczky S, Karlberg H, Klingstrom J, Lal SK, Mirazimi A, Tan YJ. An antibody against a novel and conserved epitope in the hemagglutinin 1 subunit neutralizes numerous H5N1 influenza viruses. J Virol. 2010;84:16. doi:10.1128/JVI.02593-09.
  • Ekiert DC, Bhabha G, Elsliger MA, Friesen RH, Jongeneelen M, Throsby M, Goudsmit J, Wilson IA. Antibody recognition of a highly conserved influenza virus epitope. Science. 2009;324:5924. doi:10.1126/science.1171491.
  • Sakabe S, Iwatsuki-Horimoto K, Horimoto T, Nidom CA, Le M, Takano R, Kubota-Koketsu R, Okuno Y, Ozawa M, Kawaoka Y. A cross-reactive neutralizing monoclonal antibody protects mice from H5N1 and pandemic (H1N1) 2009 virus infection. Antiviral Res. 2010;88(3):3. doi:10.1016/j.antiviral.2010.09.007.
  • Richard S, Agnes MH, And James PB. Cell penetrating antibodies for intracellular targets: expanding the antibody-based treatments for cancer. Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research. Chicago, IL. Philadelphia (PA) 2012 Mar 31-Apr 4. p. 4637
  • Kaku Y, Noguchi A, Hotta K, Yamada A, Inoue S. Inhibition of rabies virus propagation in mouse neuroblastoma cells by an intrabody against the viral phosphoprotein. Antiviral Res. 2011;91(1):1. doi:10.1016/j.antiviral.2011.04.016.
  • Goncalves J, Silva F, Freitas-Vieira A, Santa-Marta M, Malho R, Yang X, Gabuzda D, Barbas C 3rd. Functional neutralization of HIV-1 Vif protein by intracellular immunization inhibits reverse transcription and viral replication. J Biol Chem. 2002;277(35):35. doi:10.1074/jbc.M201906200.
  • Xun Y, Pan Q, Tang Z, Chen X, Yu Y, Xi M, Zang G. Intracellular-delivery of a single-chain antibody against hepatitis B core protein via cell-penetrating peptide inhibits hepatitis B virus replication in vitro. Int J Mol Med. 2013;31(2):2. doi:10.3892/ijmm.2012.1210.
  • Karthe J, Tessmann K, Li J, Machida R, Daleman M, Haussinger D, Heintges T. Specific targeting of hepatitis C virus core protein by an intracellular single-chain antibody of human origin. Hepatology. 2008;48(3):3. doi:10.1002/hep.22366.
  • Vascotto F, Campagna M, Visintin M, Cattaneo A, Burrone OR. Effects of intrabodies specific for rotavirus NSP5 during the virus replicative cycle. J Gen Virol. 2004;85(11):3285–90. Pt 11. doi:10.1099/vir.0.80075-0.
  • Corte-Real S, Collins C, Aires da Silva F, Simas JP, Barbas CF 3rd, Chang Y, Moore P, Goncalves J. Intrabodies targeting the Kaposi sarcoma-associated herpesvirus latency antigen inhibit viral persistence in lymphoma cells. Blood. 2005;106:12. doi:10.1182/blood-2005-04-1627.
  • Ashour J, Schmidt FI, Hanke L, Cragnolini J, Cavallari M, Altenburg A, Brewer R, Ingram J, Shoemaker C, Ploegh HL. Intracellular expression of camelid single-domain antibodies specific for influenza virus nucleoprotein uncovers distinct features of its nuclear localization. J Virol. 2015;89(5):5. doi:10.1128/JVI.02693-14.