Available evidence and potential for vaccines for reduction in antibiotic prescriptions

References

• WHO. Antimicrobial resistance. Fact sheets. 2021 Nov 17. https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance.
   Google Scholar
• WHO. WHO strategic priorities on antimicrobial resistance. Preserving antimicrobials for today and tomorrow. WHO; 2021. https://apps.who.int/iris/bitstream/handle/10665/351719/9789240041387-eng.pdf?sequence=1&isAllowed=y.
   Google Scholar
• Murray CJ, Ikuta KS, Sharara F, Swetschinski L, Robles Aguilar G, Gray A, Han C, Bisignano C, Rao P, Wool E, et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet. 2022;399(10325):629–8. doi:10.1016/S0140-6736(21)02724-0.
   PubMed Web of Science ®Google Scholar
• OECD. Stemming the superbug tide: just a few dollars more. In: OECD health policy studies. Paris: OECD Publishing; 2018. doi:10.1787/9789264307599-en.
   Google Scholar
• Tagliabue A, Rappuoli R. Changing priorities in vaccinology: antibiotic resistance moving to the top. Front Immunol. 2018;9:1068. doi:10.3389/fimmu.2018.01068.
   PubMed Web of Science ®Google Scholar
• Cassini A, Högberg LD, Plachouras D, Quattrocchi A, Hoxha A, Simonsen GS, Colomb-Cotinat M, Kretzschmar ME, Devleesschauwer B, Cecchini M, et al. Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis. Lancet Infect Dis. 2019;19(1):56–66. doi:10.1016/S1473-3099(18)30605-4.
   PubMed Web of Science ®Google Scholar
• European Centre for Disease Prevention and Control. Antimicrobial resistance in the EU/EEA (EARS-Net) - Annual Epidemiological Report 2020. Stockholm: ECDC; 2022. https://www.ecdc.europa.eu/sites/default/files/documents/AER-EARS-Net-2020.pdf.
   Google Scholar
• ECDC. Antibiotic resistance: how does antibiotic resistance spread? Infographic. [accessed 2014 Nov 18]. https://www.ecdc.europa.eu/en/publications-data/antibiotic-resistance-how-does-antibiotic-resistance-spread.
   Google Scholar
• WHO. Quadripartite Memorandum of Understanding (MoU) signed for a new era of One Health collaboration. 2022 Apr 22. https://www.who.int/news/item/29-04-2022-quadripartite-memorandum-of-understanding-mou-signed-for-a-new-era-of-one-health-collaboration.
   Google Scholar
• European Commission. Communication from the Commission to the Council and the European Parliament “A European One Health Action Plan against antimicrobial resistance (AMR)”. 2017 Jun 29. https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52017DC0339&from=IT.
   Google Scholar
• Pezzotti P, Bellino S, Prestinaci F, Iacchini S, Lucaroni F, Camoni L, Barbieri MM, Ricciardi W, Stefanelli P, Rezza G. The impact of immunization programs on 10 vaccine preventable diseases in Italy: 1900–2015. Vaccine. 2018;36(11):1435–43. doi:10.1016/j.vaccine.2018.01.065.
   PubMed Web of Science ®Google Scholar
• WHO. Leveraging vaccines to reduce antibiotic use and prevent antimicrobial resistance: an action framework. World Health; 2020.
   Google Scholar
• Alghamdi S. The role of vaccines in combating antimicrobial resistance (AMR) bacteria. Saudi J Biol Sci. 2021;28(12):7505–10. doi:10.1016/j.sjbs.2021.08.054.
   PubMed Web of Science ®Google Scholar
• Malarski M, Hasso-Agopsowicz M, Soble A, Mok W, Mathewson S, Vekemans J. Vaccine impact on antimicrobial resistance to inform Gavi, the Vaccine Alliance’s 2018 vaccine investment strategy: report from an expert survey. F1000Res. 2019;8:1685. doi:10.12688/f1000research.20100.1.
   PubMedGoogle Scholar
• Jansen KU, Anderson AS. The role of vaccines in fighting antimicrobial resistance (AMR). Hum Vaccin Immunother. 2018;14(9):2142–49. doi:10.1080/21645515.2018.1476814.
   PubMed Web of Science ®Google Scholar
• Jit M, Cooper B. The role of vaccines in combating antimicrobial resistance. In: North J, Anderson M, Cecchini M, and Mossialos E, editors. Challenges to tackling antimicrobial resistance: economic and policy responses (European Observatory on Health Systems and Policies). Cambridge: Cambridge University Press; 2020. p. 181–206. doi:10.1017/9781108864121.009.
   Google Scholar
• Andrejko K, Ratnasiri B, Hausdorff WP, Laxminarayan R, Lewnard JA. Antimicrobial resistance in paediatric Streptococcus pneumoniae isolates amid global implementation of pneumococcal conjugate vaccines: a systematic review and meta-regression analysis. Lancet Microbe. 2021;2(9):e450–60. PMID: 34485957; PMCID: PMC8410609. doi:10.1016/S2666-5247(21)00064-1.
   PubMedGoogle Scholar
• Micoli F, Bagnoli F, Rappuoli R, Serruto D. The role of vaccines in combatting antimicrobial resistance. Nat Rev Microbiol. 2021;19(5):287–302. doi:10.1038/s41579-020-00506-3.
   PubMed Web of Science ®Google Scholar
• Oliver SE. Chapter 2: Haemophilus influenzae invasive disease. In: VPD Surveillance Manual. [ accessed 2019 Oct 25]. https://www.cdc.gov/vaccines/pubs/surv-manual/chpt02-hib.html.
   Google Scholar
• Slack M, Esposito S, Haas H, Mihalyi A, Nissen M, Mukherjee P, Harrington L. Haemophilus influenzae type b disease in the era of conjugate vaccines: critical factors for successful eradication. Expert Rev Vaccines. 2020;19(10):903–17. doi:10.1080/14760584.2020.1825948.
   PubMed Web of Science ®Google Scholar
• Heliodoro CIM, Bettencourt CR, Bajanca-Lavado MP, Portuguese Group for the Study of Haemophilus influenzae invasive infection. Molecular epidemiology of invasive Haemophilus influenzae disease in Portugal: an update of the post-vaccine period, 2011–2018. Eur J Clin Microbiol Infect Dis. 2020;39(8):1471–80. doi:10.1007/s10096-020-03865-0.
   PubMedGoogle Scholar
• McElligott M, Meyler K, Bennett D, Mulhall R, Drew RJ, Cunney R. Epidemiology of Haemophilus influenzae in the Republic of Ireland, 2010–2018. Eur J Clin Microbiol Infect Dis. 2020;39(12):2335–44. doi:10.1007/s10096-020-03971-z.
   PubMedGoogle Scholar
• Wen S, Feng D, Chen D, Yang L, Xu Z. Molecular epidemiology and evolution of Haemophilus influenzae. Infect Genet Evol. 2020;80:104205. doi:10.1016/j.meegid.2020.104205.
   PubMed Web of Science ®Google Scholar
• Gierke R, McGee L, Beall B, Pilishvili T. Chapter 11: pneumococcal. In: VPD surveillance manual. [accessed 2020 Jun 29]. https://www.cdc.gov/vaccines/pubs/surv-manual/chpt11-pneumo.html.
   Google Scholar
• Laxminarayan R, Matsoso P, Pant S, Brower C, Røttingen JA, Klugman K, Davies S. Access to effective antimicrobials: a worldwide challenge. Lancet. 2016;387(10014):168–75. doi:10.1016/S0140-6736(15)00474-2.
   PubMed Web of Science ®Google Scholar
• Lu EY, Chen HH, Zhao H, Ozawa S. Health and economic impact of the pneumococcal conjugate vaccine in hindering antimicrobial resistance in China. Proc Natl Acad Sci USA. 2021;118(13):e2004933118. doi:10.1073/pnas.2004933118.
   PubMedGoogle Scholar
• Blasi F, Bonanni P, Braido F, Gabutti G, Marchetti F, Centanni S. The unmet need for pertussis prevention in patients with chronic obstructive pulmonary disease in the Italian context. Hum Vaccin Immunother. 2020;16(2):340–48. doi:10.1080/21645515.2019.1652517.
   PubMed Web of Science ®Google Scholar
• Lee GM, Lett S, Schauer S, LeBaron C, Murphy TV, Rusinak D, Lieu TA, Massachusetts Pertussis Study Group. Societal costs and morbidity of pertussis in adolescents and adults. Clin Infect Dis. 2004;39(11):1572–80. doi:10.1086/425006.
   PubMed Web of Science ®Google Scholar
• Moore A, Harnden A, Grant CC, Patel S, Irwin RS, Altman KW, Azoulay E, Barker AF, Bolser DC, Birring SS, CHEST Expert Cough Panel. Clinically diagnosing pertussis-associated cough in adults and children: CHEST Guideline and Expert Panel Report. Chest. 2019;155(1):147–54. doi:10.1016/j.chest.2018.09.027.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention (CDC). Diagnosis confirmation. 2019. [ accesso 2022 Gennaio]. https://www.cdc.gov/pertussis/clinical/diagnostic-testing/diagnosis-confirmation.html.
   Google Scholar
• Kinkade S, Long NA. Acute bronchitis. Am Fam Physician. 2016;94(7):560–65. PMID: 27929206.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention (CDC). Cold vs Flu. https://www.cdc.gov/flu/symptoms/coldflu.htm.
   Google Scholar
• Bhavsar A, Aris E, Harrington L, Simeone JC, Ramond A, Lambrelli D, Papi A, Boulet LP, Meszaros K, Jamet N, et al. Burden of pertussis in individuals with a diagnosis of asthma: a retrospective database study in England. J Asthma Allergy. 2022;15:35–51. doi:10.2147/JAA.S335960.
   PubMed Web of Science ®Google Scholar
• Marchetti F, Prato R, Viale P. Survey among Italian experts on existing vaccines’ role in limiting antibiotic resistance. Human Vaccin Immunother. 2021;17(11):4283–90. doi:10.1080/21645515.2021.1969853.
   PubMed Web of Science ®Google Scholar
• Buchy P, Ascioglu S, Buisson Y, Datta S, Nissen M, Tambyah PA, Vong S. Impact of vaccines on antimicrobial resistance. Int J Infect Dis. 2020;90:188–96. doi:10.1016/j.ijid.2019.10.005.
   PubMed Web of Science ®Google Scholar
• Klugman KP, Black S. Impact of existing vaccines in reducing antibiotic resistance: primary and secondary effects. Proc Natl Acad Sci USA. 2018;115(51):12896–901. doi:10.1073/pnas.1721095115.
   PubMed Web of Science ®Google Scholar
• Giacchetta I, Primieri C, Cavalieri R, Domnich A, de Waure C. The burden of seasonal influenza in Italy: a systematic review of influenza-related complications, hospitalizations, and mortality. Influenza Other Respir Viruses. 2022;16(2):351–65. doi:10.1111/irv.12925.
   PubMed Web of Science ®Google Scholar
• Grohskopf LA, Alyanak E, Broder KR, Blanton LH, Fry AM, Jernigan DB, Atmar RL. Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices — United States, 2020–21 influenza season. MMWR Recomm Rep. 2020;69(8):1–24. doi:10.15585/mmwr.rr6908a1.
   PubMed Web of Science ®Google Scholar
• Kwong JC, Maaten S, Upshur RE, Patrick DM, Marra F. The effect of universal influenza immunization on antibiotic prescriptions: an ecological study. Clin Infect Dis. 2009;49(5):750–56. doi:10.1086/605087.
   PubMed Web of Science ®Google Scholar
• Piltcher OB, Kosugi EM, Sakano E, Mion O, Testa JRG, Romano FR, Santos MCJ, Di Francesco RC, Mitre EI, Bezerra TFP, et al. How to avoid the inappropriate use of antibiotics in upper respiratory tract infections? A position statement from an expert panel. Braz J Otorhinolaryngol. 2018;84(3):265–79. doi:10.1016/j.bjorl.2018.02.001.
   PubMed Web of Science ®Google Scholar
• Jackson ML, Phillips CH, Benoit J, Jackson LA, Gaglani M, Murthy K, McLean HQ, Belongia EA, Malosh R, Zimmerman R, et al. Burden of medically attended influenza infection and cases averted by vaccination – United States, 2013/14 through 2015/16 influenza seasons. Vaccine. 2018;36(4):467–72. doi:10.1016/j.vaccine.2017.12.014.
   PubMed Web of Science ®Google Scholar
• Klein EY, Schueller E, Tseng KK, Morgan DJ, Laxminarayan R, Nandi A. The impact of influenza vaccination on antibiotic use in the United States, 2010-2017. Open Forum Infect Dis. 2020;7(7):ofaa223. PMID: 32665959; PMCID: PMC7336555. doi:10.1093/ofid/ofaa223.
   PubMed Web of Science ®Google Scholar
• Knight GM, Clarkson M, de Silva TI. Potential impact of influenza vaccine roll-out on antibiotic use in Africa. J Antimicrob Chemother. 2018;73(8):2197–200. doi:10.1093/jac/dky172.
   PubMed Web of Science ®Google Scholar
• Esposito S, Principi N, European Society of Clinical Microbiology Infectious Diseases (ESCMID) Vaccine Study Group (EVASG). Influenza vaccination and prevention of antimicrobial resistance. Expert Rev Vaccines. 2018;17(10):881–88. doi:10.1080/14760584.2018.1525298.
   PubMed Web of Science ®Google Scholar
• Muller-Pebody B, Sinnathamby MA, Warburton F, Rooney G, Andrews N, Whitaker H, Henderson KL, Tsang C, Hopkins S, Pebody RG. Impact of the childhood influenza vaccine programme on antibiotic prescribing rates in primary care in England. Vaccine. 2021;39(45):6622–27. doi:10.1016/j.vaccine.2021.09.069.
   PubMed Web of Science ®Google Scholar
• Barchitta M, Maugeri A, Vinci R, Agodi A. The inverse relationship between influenza vaccination and antimicrobial resistance: an ecological analysis of Italian data. Vaccines (Basel). 2022;10(4):554. doi:10.3390/vaccines10040554.
   PubMed Web of Science ®Google Scholar
• Yin M, Huang L, Zhang Y, Yu N, Xu X, Liang Y, Ni J. Effectiveness and safety of dual influenza and pneumococcal vaccination versus separate administration or no vaccination in older adults: a meta-analysis. Expert Rev Vaccines. 2018;17(7):653–63. doi:10.1080/14760584.2018.1495077.
   PubMed Web of Science ®Google Scholar
• Vandenhaute J, Tsakeu E, Chevalier P, Pawaskar M, Benčina G, Vertriest J. Assessing the use of antibiotics and the burden of varicella in Belgium using a retrospective GP database analysis. BMC Infect Dis. 2021;21(1):1150. doi:10.1186/s12879-021-06848-4.
   PubMed Web of Science ®Google Scholar
• Pawaskar M, Fergie J, Harley C, Samant S, Veeranki P, Diaz O, Conway JH. Impact of universal varicella vaccination on the use and cost of antibiotics and antivirals for varicella management in the United States. PLoS One. 2022;17(6):e0269916. doi:10.1371/journal.pone.0269916.
   PubMed Web of Science ®Google Scholar
• Hall EW, Tippett A, Fridkin S, Anderson EJ, Lopman B, Benkeser D, Baker JM. Association between rotavirus vaccination and antibiotic prescribing among commercially insured US children, 2007-2018. Open Forum Infect Dis. 2022;9(7):ofac276. doi:10.1093/ofid/ofac276.
   PubMed Web of Science ®Google Scholar
• Burke RM, Tate JE, Kirkwood CD, Steele AD, Parashar UD. Current and new rotavirus vaccines. Curr Opin Infect Dis. 2019 Oct;32(5):435–44. doi:10.1097/QCO.0000000000000572.
   PubMed Web of Science ®Google Scholar
• CDC. Rotavirus. https://www.cdc.gov/rotavirus/index.html.
   Google Scholar
• Nam HH, Ison MG. Respiratory syncytial virus. Semin Respir Crit Care Med. 2021;42(6):788–99. Epub 2021 Dec 16. PMID: 34918321. doi:10.1055/s-0041-1736182.
   PubMedGoogle Scholar
• Obolski U, Kassem E, Na’Amnih W, Tannous S, Kagan V, Muhsen K. Unnecessary antibiotic treatment of children hospitalised with respiratory syncytial virus (RSV) bronchiolitis: risk factors and prescription patterns. J Glob Antimicrob Resist. 2021;27:303–08. doi:10.1016/j.jgar.2021.10.015.
   PubMed Web of Science ®Google Scholar
• Fitzpatrick T, Malcolm W, McMenamin J, Reynolds A, Guttmann A, Hardelid P. Community-based antibiotic prescribing attributable to Respiratory Syncytial Virus and other common respiratory viruses in young children: a population-based time-series study of Scottish children. Clin Infect Dis. 2021;72(12):2144–53. doi:10.1093/cid/ciaa403.
   PubMed Web of Science ®Google Scholar
• Hartnett J, Donga P, Ispas G, Vandendijck Y, Anderson D, House S, Suner S. Risk factors and medical resource utilization in US adults hospitalized with influenza or respiratory syncytial virus in the hospitalized acute respiratory tract infection study. Influenza Other Respir Viruses. 2022;16(5):906–15. doi:10.1111/irv.12994.
   PubMed Web of Science ®Google Scholar
• Walsh E, Lee N, Sander I, Stolper R, Zakar J, Wyffels V, Myers D, Fleischhackl R. RSV-associated hospitalization in adults in the USA: a retrospective chart review investigating burden, management strategies, and outcomes. Health Sci Rep. 2022;5(3):e556. doi:10.1002/hsr2.556.
   PubMedGoogle Scholar
• Mazur NI, Terstappen J, Baral R, Bardají A, Beutels P, Buchholz UJ, Cohen C, Crowe JE Jr, Cutland CL, Eckert L, et al. Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape. Lancet Infect Dis. 2022;S1473-3099(22):00291–2. doi:10.1016/S1473-3099(22)00291-2.
   Google Scholar
• Jansen KU, Gruber WC, Simon R, Wassil J, Anderson AS. The impact of human vaccines on bacterial antimicrobial resistance. A review. Environ Chem Lett. 2021;19(6):4031–62. doi:10.1007/s10311-021-01274-z.
   PubMed Web of Science ®Google Scholar
• Doherty TM, Hausdorff WP, Kristinsson KG. Effect of vaccination on the use of antimicrobial agents: a systematic literature review. Ann Med. 2020;52(6):283–99. Epub 2020 Jun 29. PMID: 32597236; PMCID: PMC7880080. doi:10.1080/07853890.2020.1782460. .
   PubMed Web of Science ®Google Scholar
• WHO. Global action plan on antimicrobial resistance. 2015. https://www.who.int/publications/i/item/9789241509763.
   Google Scholar