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Bioengineered Volume 11, 2020 - Issue 1
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Research Paper

Peroxisome proliferator-activated receptor γ (PPARγ) suppresses the proliferation and metastasis of patients with urothelial carcinoma after renal transplantation by inhibiting LEF1/β-catenin signaling

Donghao Shanga Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaORCID Iconhttps://orcid.org/0000-0002-3782-6514View further author information
ORCID Icon,
Yuting Liub Department of Pathology, Capital Medical University, Beijing, ChinaCorrespondence[email protected]
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,
Jian Zhanga Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaView further author information
&
Xinyi Hua Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaView further author information
Pages 1350-1367 | Received 26 May 2020, Accepted 26 Oct 2020, Published online: 08 Dec 2020

References

  • Shang D, Zheng T, Zhang J, et al. Profiling of mRNA and long non-coding RNA of urothelial cancer in recipients after renal transplantation. Tumour Biol. 2016;37(9):12673–12684.
  • Santiago L, Daniels G, Wang D, et al. Wnt signaling pathway protein LEF1 in cancer, as a biomarker for prognosis and a target for treatment. Am J Cancer Res. 2017;7(6):1389–1406.
  • Nusse R, Clevers H. Wnt/beta-catenin signaling, disease, and emerging therapeutic modalities. Cell. 2017;169(6):985–999.
  • Clevers H, Nusse R. Wnt/beta-catenin signaling and disease. Cell. 2012;149(6):1192–1205.
  • Cheng Z, Limbu MH, Wang Z, et al. MMP-2 and 9 in chronic kidney disease. Int J Mol Sci. 2017;18(4):776.
  • Sato H, Takino T. Coordinate action of membrane-type matrix metalloproteinase-1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion. Cancer Sci. 2010;101(4):843–847.
  • Belo VA, Guimaraes DA, Castro MM. Matrix metalloproteinase 2 as a potential mediator of vascular smooth muscle cell migration and chronic vascular remodeling in hypertension. J Vasc Res. 2015;52(4):221–231.
  • Macqueen DJ, Wilcox AH. Characterization of the definitive classical calpain family of vertebrates using phylogenetic, evolutionary and expression analyses. Open Biol. 2014;4:130219.
  • Jang HS, Lal S, Greenwood JA. Calpain 2 is required for glioblastoma cell invasion: regulation of matrix metalloproteinase 2. Neurochem Res. 2010;35(11):1796–1804.
  • Li TW, Ting JH, Yokoyama NN, et al. Wnt activation and alternative promoter repression of LEF1 in colon cancer. Mol Cell Biol. 2006;26(14):5284–5299.
  • Shang D, Bi R, Han T, et al. Expression and proliferation-promoting role of lymphoid enhancer-binding factor 1 in human clear cell renal carcinoma. Cancer Invest. 2014;32(7):368–374.
  • Eichhoff OM, Weeraratna A, Zipser MC, et al. Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching. Pigment Cell Melanoma Res. 2011;24(4):631–642.
  • Nguyen DX, Chiang AC, Zhang XH, et al. WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. Cell. 2009;138(1):51–62.
  • Bi JB, Zhu Y, Chen XL, et al. The role of fascin in migration and invasion of urothelial carcinoma of the bladder. Urol Int. 2013;91(2):227–235.
  • Lecarpentier Y, Claes V, Vallée A, et al. Interactions between PPAR gamma and the canonical Wnt/Beta-catenin pathway in type 2 diabetes and colon cancer. Hindawi. 2017;5:1–9.
  • Kasiske BL, Snyder JJ, Gilbertson DT, et al. Cancer after kidney transplantation in the United States. Am J Transplant. 2004;4(6):905–913.
  • Li HZ, Xia M, Han Y, et al. De novo urothelial carcinoma in kidney transplantation patients with end-stage aristolochic acid nephropathy in China. Urol Int. 2009;83(2):200–205.
  • Stiborova M, Frei E, Schmeiser HH, et al. Mechanisms of enzyme-catalyzed reduction of two carcinogenic nitro-aromatics, 3-nitrobenzanthrone and aristolochic acid I: experimental and theoretical approaches. Int J Mol Sci. 2014;15(6):10271–10295.

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