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Bioengineered Volume 12, 2021 - Issue 1
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Research Paper

Long non-coding RNA histone deacetylase 4 antisense RNA 1 (HDAC4-AS1) inhibits HDAC4 expression in human ARPE-19 cells with hypoxic stress

Jie PanDepartment of Ophthalmology, ZiBo Central Hospital, Zibo City, People’s Republic of China
&
Luxin ZhaoDepartment of Ophthalmology, ZiBo Central Hospital, Zibo City, People’s Republic of ChinaCorrespondence[email protected]
Pages 2228-2237 | Received 17 Mar 2021, Accepted 19 May 2021, Published online: 30 May 2021

References

  • Fritsche LG, Chen W, Schu M, et al. Seven new loci associated with age-related macular degeneration. Nat Genet. 2013;45:433–9, 9e1-2.
  • Song P, Du Y, Chan KY, et al. The national and subnational prevalence and burden of age-related macular degeneration in China. J Glob Health. 2017;7:020703.
  • Ohno-Matsui K, Ikuno Y, Lai TYY, et al. Diagnosis and treatment guideline for myopic choroidal neovascularization due to pathologic myopia. Prog Retin Eye Res. 2018;63:92–106.
  • Klettner A, Kaya L, Flach J, et al. Basal and apical regulation of VEGF-A and placenta growth factor in the RPE/choroid and primary RPE. Mol Vis. 2015;21:736–748.
  • Schlingemann RO. Role of growth factors and the wound healing response in age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2004;242:91–101.
  • Zhu M, Liu X, Wang S, et al. PKR promotes choroidal neovascularization via upregulating the PI3K/Akt signaling pathway in VEGF expression. Mol Vis. 2016;22:1361–1374.
  • Sun YZ, Cai N, Liu NN. Celecoxib down-regulates the hypoxia-induced expression of HIF-1alpha and VEGF through the PI3K/AKT pathway in retinal pigment epithelial cells. Cell Physiol Biochem. 2017;44:1640–1650.
  • Ke Q, Costa M. Hypoxia-inducible factor-1 (HIF-1). Mol Pharmacol. 2006;70:1469–1480.
  • Janardhan HP. The HIF-1 alpha-C/EBP alpha axis. Sci Signal. 2008;1:jc2.
  • Schmitz SU, Grote P, Herrmann BG. Mechanisms of long noncoding RNA function in development and disease. Cell Mol Life Sci. 2016;73:2491–2509.
  • Zhu W, Meng YF, Xing Q, et al. Identification of lncRNAs involved in biological regulation in early age-related macular degeneration. Int J Nanomedicine. 2017;12:7589–7602.
  • Chen X, Jiang C, Qin B, et al. LncRNA ZNF503-AS1 promotes RPE differentiation by downregulating ZNF503 expression. Cell Death Dis. 2017;8:e3046.
  • Yu X, Luo Y, Chen G, et al. Long non-coding RNA PWRN2 regulates cytotoxicity in an in vitro model of age-related macular degeneration. Biochem Biophys Res Commun. 2021;535:39–46.
  • Bolger AM, Lohse M, Usadel B. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics. 2014;30:2114–2120.
  • de Sena Brandine, G, Smith AD. Falco: high-speed FastQC emulation for quality control of sequencing data. F1000Res. 2019; 8:1874.
  • Kim D, Langmead B, Salzberg SL. HISAT: a fast spliced aligner with low memory requirements. Nat Methods. 2015;12:357–360.
  • Pertea M, Pertea GM, Antonescu CM, et al. StringTie enables improved reconstruction of a transcriptome from RNA-seq reads. Nat Biotechnol. 2015;33:290–295.
  • Frazee AC, Pertea G, Jaffe AE, et al. Ballgown bridges the gap between transcriptome assembly and expression analysis. Nat Biotechnol. 2015;33:243–246.
  • Yu G, Wang LG, Han Y, et al. clusterProfiler: an R package for comparing biological themes among gene clusters. OMICS. 2012;16:284–287.
  • He S, Zhang H, Liu H, et al. LongTarget: a tool to predict lncRNA DNA-binding motifs and binding sites via Hoogsteen base-pairing analysis. Bioinformatics. 2015;31:178–186.
  • Kurihara T. Roles of hypoxia response in retinal development and pathophysiology. Keio J Med. 2018;67:1–9.
  • Yang F, Zhang H, Mei Y, et al. Reciprocal regulation of HIF-1alpha and lincRNA-p21 modulates the Warburg effect. Mol Cell. 2014;53:88–100.
  • Yokota K, Tanaka Y, Harada H, et al. WiNTRLINC1/ASCL2/c-Myc axis characteristics of colon cancer with differentiated histology at young onset and essential for cell viability. Ann Surg Oncol. 2019;26:4826–4834.
  • Yan F, Wang X, Zeng Y. 3D genomic regulation of lncRNA and Xist in X chromosome. Semin Cell Dev Biol. 2019;90:174–180.
  • Pinto D, Delaby E, Merico D, et al. Convergence of genes and cellular pathways dysregulated in autism spectrum disorders. Am J Hum Genet. 2014;94:677–694.
  • Dahbash M, Sella R, Megiddo-Barnir E, et al. The histone deacetylase inhibitor AN7, attenuates choroidal neovascularization in a mouse model. Int J Mol Sci. 2019:20. doi:10.3390/ijms20030714.
  • Chen B, Cepko CL. HDAC4 regulates neuronal survival in normal and diseased retinas. Science. 2009;323:256–259.
  • Geng H, Harvey CT, Pittsenbarger J, et al. HDAC4 protein regulates HIF1alpha protein lysine acetylation and cancer cell response to hypoxia. J Biol Chem. 2011;286:38095–38102.
  • Seo HW, Kim EJ, Na H, et al. Transcriptional activation of hypoxia-inducible factor-1alpha by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1. FEBS Lett. 2009;583:55–60.

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