PAX6 upstream antisense RNA (PAUPAR) inhibits colorectal cancer progression through modulation of the microRNA (miR)-17-5p / zinc finger protein 750 (ZNF750) axis

References

• Keum N, Giovannucci E. Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies. Nat Rev Gastroenterol Hepatol. 2019;16(12):713–732.
   PubMed Web of Science ®Google Scholar
• Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424.
   PubMed Web of Science ®Google Scholar
• Jeong S, Kim DY, Kang SH, et al. Docosahexaenoic acid enhances oxaliplatin-induced autophagic cell death via the ER Stress/Sesn2 pathway in colorectal cancer. Cancers (Basel). 2019;11(7):982.
   Web of Science ®Google Scholar
• Huang M, Xie X, Song X, et al. MiR-506 suppresses colorectal cancer development by inhibiting orphan nuclear receptor NR4A1 expression. J Cancer. 2019;10(15):3560–3570.
   PubMed Web of Science ®Google Scholar
• Robinson EK, Covarrubias S, Carpenter S. The how and why of lncRNA function: an innate immune perspective. Biochim Biophys Acta Gene Regul Mech. 2020;1863(4):194419.
   PubMed Web of Science ®Google Scholar
• Jathar S, Kumar V, Srivastava J, et al. Technological developments in lncRNA biology. Adv Exp Med Biol. 2017;1008:283–323.
   PubMed Web of Science ®Google Scholar
• Paraskevopoulou MD, Hatzigeorgiou AG. Analyzing MiRNA-LncRNA interactions. Methods Mol Biol. 2016;1402:271–286.
   PubMedGoogle Scholar
• Ghafouri-Fard S, Taheri M. A comprehensive review of non-coding RNAs functions in multiple sclerosis. Eur J Pharmacol. 2020;879:173127.
   PubMed Web of Science ®Google Scholar
• Peng WX, Koirala P, Mo YY. LncRNA-mediated regulation of cell signaling in cancer. Oncogene. 2017;36(41):5661–5667.
   PubMed Web of Science ®Google Scholar
• Bhan A, Soleimani M, Mandal SS. Long noncoding RNA and cancer: a new paradigm. Cancer Res. 2017;77(15):3965–3981.
   PubMed Web of Science ®Google Scholar
• Wu Y, Yang X, Chen Z, et al. m(6)A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1. Mol Cancer. 2019;18(1):87.
   PubMedGoogle Scholar
• Tang J, Yan T, Bao Y, et al. LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc. Nat Commun. 2019;10(1):3499.
   PubMed Web of Science ®Google Scholar
• Huang JZ, Chen M, Chen D, et al. A peptide encoded by a putative lncRNA HOXB-AS3 suppresses colon cancer growth. Mol Cell. 2017;68(1):171–84.e6.
   PubMed Web of Science ®Google Scholar
• Pavlaki I, Alammari F, Sun B, et al. The long non-coding RNA Paupar promotes KAP1-dependent chromatin changes and regulates olfactory bulb neurogenesis. Embo J. 2018;37(10). DOI:10.15252/embj.201798219
   PubMed Web of Science ®Google Scholar
• Ding X, Wang X, Lin M, et al. PAUPAR lncRNA suppresses tumourigenesis by H3K4 demethylation in uveal melanoma. FEBS Lett. 2016;590(12):1729–1738.
   PubMed Web of Science ®Google Scholar
• Shirmohamadi M, Eghbali E, Najjary S, et al. Regulatory mechanisms of microRNAs in colorectal cancer and colorectal cancer stem cells. J Cell Physiol. 2020;235(2):776–789.
   PubMed Web of Science ®Google Scholar
• Mitra R, Adams CM, Jiang W, et al. Pan-cancer analysis reveals cooperativity of both strands of microRNA that regulate tumorigenesis and patient survival. Nat Commun. 2020;11(1):968.
   PubMed Web of Science ®Google Scholar
• Liu Z, Liu X, Li Y, et al. miR-6716-5p promotes metastasis of colorectal cancer through downregulating NAT10 expression. Cancer Manag Res. 2019;11:5317–5332.
   PubMed Web of Science ®Google Scholar
• Xiao Y, Li ZH, Bi YH. MicroRNA-889 promotes cell proliferation in colorectal cancer by targeting DAB2IP. Eur Rev Med Pharmacol Sci. 2019;23(8):3326–3334.
   PubMed Web of Science ®Google Scholar
• Zhang H, Zhu M, Shan X, et al. A panel of seven-miRNA signature in plasma as potential biomarker for colorectal cancer diagnosis. Gene. 2019;687:246–254.
   PubMed Web of Science ®Google Scholar
• Qu J, Zhang X, Lv X. Zinc finger protein 750(ZNF750), negatively regulated by miR-17-5p, inhibits proliferation, motility and invasion of colonic cancer cells. J Gene Med. 2020;22:e3195.
   PubMed Web of Science ®Google Scholar
• Zhang P, He Q, Lei Y, et al. m(6)A-mediated ZNF750 repression facilitates nasopharyngeal carcinoma progression. Cell Death Dis. 2018;9(12):1169.
   PubMed Web of Science ®Google Scholar
• Li J, Chen Y, Xu X, et al. HNRNPK maintains epidermal progenitor function through transcription of proliferation genes and degrading differentiation promoting mRNAs. Nat Commun. 2019;10(1):4198.
   PubMed Web of Science ®Google Scholar
• Otsuka R, Akutsu Y, Sakata H, et al. ZNF750 expression is a potential prognostic biomarker in esophageal squamous cell carcinoma. Oncology. 2018;94(3):142–148.
   PubMed Web of Science ®Google Scholar
• Hazawa M, Lin DC, Handral H, et al. ZNF750 is a lineage-specific tumor suppressor in squamous cell carcinoma. Oncogene. 2017;36(16):2243–2254.
   PubMed Web of Science ®Google Scholar
• Javed Z, Khan K, Sadia H, et al. LncRNA & Wnt signaling in colorectal cancer. Cancer Cell Int. 2020;20:326.
   PubMed Web of Science ®Google Scholar
• Singer RA, Arnes L, Cui Y, et al. The long noncoding RNA paupar modulates pax6 regulatory activities to promote alpha cell development and function. Cell Metab. 2019;30(6):1091–106.e8.
   PubMed Web of Science ®Google Scholar
• Zhang LL, Qi LN, Yao ZY. The role of long chain non-coding RNA-paupar in the process of bupivacaine induced neurotoxicity. Sichuan Da Xue Xue Bao Yi Xue Ban. 2017;48(6):873–876.
   PubMedGoogle Scholar
• Cai N, Hu L, Xie Y, et al. MiR-17-5p promotes cervical cancer cell proliferation and metastasis by targeting transforming growth factor-β receptor 2. Eur Rev Med Pharmacol Sci. 2018;22(7):1899–1906.
   PubMed Web of Science ®Google Scholar
• Zhao X, Xu Y, Sun X, et al. miR-17-5p promotes proliferation and epithelial-mesenchymal transition in human osteosarcoma cells by targeting SRC kinase signaling inhibitor 1. J Cell Biochem. 2019;120(4):5495–5504.
   PubMed Web of Science ®Google Scholar
• Sen GL, Boxer LD, Webster DE, et al. ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation. Dev Cell. 2012;22(3):669–677.
   PubMed Web of Science ®Google Scholar
• Pan L, Yang H, Xu C, et al. ZNF750 inhibited the malignant progression of oral squamous cell carcinoma by regulating tumor vascular microenvironment. Biomed Pharmacother. 2018;105:566–572.
   PubMed Web of Science ®Google Scholar
• Kong P, Xu E, Bi Y, et al. Novel ESCC-related gene ZNF750 as potential prognostic biomarker and inhibits epithelial-mesenchymal transition through directly depressing SNAI1 promoter in ESCC. Theranostics. 2020;10(4):1798–1813.
   PubMed Web of Science ®Google Scholar
• Neagu M, Albulescu R, Tanase C. New marker related to cancer neoangiogenesis: RGS5. Biomark Med. 2012;6(2):197–198.
   Web of Science ®Google Scholar
• Sethakorn N, Dulin NO. RGS expression in cancer: oncomining the cancer microarray data. J Recept Signal Transduct Res. 2013;33(3):166–171.
   PubMed Web of Science ®Google Scholar