Resveratrol suppresses malignant progression of oral squamous cell carcinoma cells by inducing the ZNF750/RAC1 signaling pathway

References

• Ma J, Gao W, Gao J. sCLU as prognostic biomarker and therapeutic target in osteosarcoma. Bioengineered. 2019;10(1):229–239.
   PubMed Web of Science ®Google Scholar
• Zhong L, Liu Y, Wang K, et al. Biomarkers: paving stones on the road towards the personalized precision medicine for oral squamous cell carcinoma. BMC Cancer. 2018;18:911–918.
   PubMed Web of Science ®Google Scholar
• Choi S, Myers JN. Molecular pathogenesis of oral squamous cell carcinoma: implications for therapy. J Dent Res. 2018;87:14–32.
   Google Scholar
• Junttila MR, de Sauvage FJ. Influence of tumour micro-environment heterogeneity on therapeutic response. Nature. 2013;501:346–354.
   PubMed Web of Science ®Google Scholar
• Lin DC, Hao JJ, Nagata Y, et al. Genomic and molecular characterization of esophageal squamous cell carcinoma. Nat Genet. 2014;46:467–473.
   PubMed Web of Science ®Google Scholar
• Hazawa M, Lin DC, Handral H, et al. ZNF750 is a lineage-specific tumour suppressor in squamous cell carcinoma. Oncogene. 2017;36:2243–2254.
   PubMed Web of Science ®Google Scholar
• Nambara S, Masuda T, Tobo T, et al. Clinical significance of ZNF750 gene expression, a novel tumor suppressor gene, in esophageal squamous cell carcinoma. Oncol Lett. 2017;14:1795–1801.
   PubMed Web of Science ®Google Scholar
• Otsuka R, Akutsu Y, Sakata H, et al. ZNF750 expression as a novel candidate biomarker of chemoradiosensitivity in esophageal squamous cell carcinoma. Oncology. 2017;93:197–203.
   PubMed Web of Science ®Google Scholar
• Pan L, Yang HL, Xu C, et al. ZNF750 inhibited the malignant progression of oral squamous cell carcinoma by regulating tumor vascular microenvironment. Biomed Pharmacother. 2018;105:566–572.
   PubMed Web of Science ®Google Scholar
• Acevedo A, González-Billault C. Crosstalk between Rac1-mediated actin regulation and ROS production. Free Radic Biol Med. 2018;116:101–113.
   PubMed Web of Science ®Google Scholar
• Ramírez-Ramírez D, Salgado-Lucio ML, Roa-Espitia AL, et al. Rac1 is necessary for capacitation and acrosome reaction in guinea pig spermatozoa. J Cell Biochem. 2020;121(4):2864–2876.
   PubMed Web of Science ®Google Scholar
• Bandaru S, Ala C, Ekstrand M, et al. Lack of RAC1 in macrophages protects against atherosclerosis. PLoS One. 2020;15(9):e0239284.
   PubMed Web of Science ®Google Scholar
• Winge MCG, Marinkovich MP. Epidermal activation of the small GTPase Rac1 in psoriasis pathogenesis. Small GTPases. 2019;10(3):163–168.
   PubMedGoogle Scholar
• Ma L, Ma Y, Zhang Z, et al. The signaling axis of Rac1-TFEB regulates autophagy and tumorigenesis. Anticancer Drugs. 2019;30(10):1031–1037.
   PubMed Web of Science ®Google Scholar
• Berlew EE, Kuznetsov IA, Yamada K, et al. Optogenetic Rac1 engineered from membrane lipid-binding RGS-LOV for inducible lamellipodia formation. Photochem Photobiol Sci. 2020;19(3):353–361.
   PubMed Web of Science ®Google Scholar
• Butera A, Cassandri M, Rugolo F, et al. The ZNF750-RAC1 axis as potential prognostic factor for breast cancer. Cell Death Discov. 2020;6(1):135–142.
   PubMed Web of Science ®Google Scholar
• Goel S, Duda DG, Xu L, et al. Normalization of the vasculature for treatment of cancer and other diseases. Physiol Rev. 2011;91:1071–1121.
   PubMed Web of Science ®Google Scholar
• Cho SH, Park YS, Kim HJ, et al. CD44 enhances the epithelial-mesenchymal transition in association with colon cancer invasion. Int J Oncol. 2012;41:211–218.
   PubMed Web of Science ®Google Scholar
• Zhao Y, Miao G, Li Y, et al. MicroRNA- 130b suppresses migration and invasion of colorectal cancer cells through downregulation of integrin beta1. PLoS One. 2014;9(2):e87938.
   PubMed Web of Science ®Google Scholar
• Ohyagi-Hara C, Sawada K, Kamiura S, et al. miR-92a inhibits peritoneal dissemination of ovarian cancer cells by inhibiting integrin alpha5 expression. Am J Pathol. 2013;182:1876–1889.
   PubMed Web of Science ®Google Scholar
• Valenzano DR, Terzibasi E, Genade T, et al. Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate. Curr Biol. 2006;16:296–300.
   PubMed Web of Science ®Google Scholar
• Jie Y, Ye L, Chen H, et al. ELFN1-AS1 accelerates cell proliferation, invasion and migration via regulating miR-497-3p/CLDN4 axis in ovarian cancer. Bioengineered. 2020;11(1):872–882.
   PubMed Web of Science ®Google Scholar
• Treasure J. Herbal medicine and cancer: an introductory overview. Semin Oncol Nurs. 2005;21:177–183.
   PubMedGoogle Scholar
• Cao YJ, Pu ZJ, Tang YP, et al. Advances in bio-active constituents, pharmacology and clinical applications of rhubarb. Chin Med. 2017;12:36–46.
   PubMed Web of Science ®Google Scholar
• Rauf A, Imran M, Suleria HAR, et al. A comprehensive review of the health perspectives of resveratrol. Food Funct. 2017;8:4284–4305.
   PubMed Web of Science ®Google Scholar
• Thaung Zaw JJ, Howe PRC, Wong RHX, et al. Does phytoestrogen supplementation improve cognition in humans? A systematic review. Ann N Y Acad Sci. 2017;1403:150–163.
   PubMed Web of Science ®Google Scholar
• Xia N, Daiber A, Förstermann U, et al. Antioxidant effects of resveratrol in the cardiovascular system. Br J Pharmacol. 2017;174:1633–1646.
   PubMed Web of Science ®Google Scholar
• Wu JY, Yi C, Chung HR, et al. Potential biomarkers in saliva for oral squamous cell carcinoma. Oral Oncol. 2010;46:226–231.
   PubMed Web of Science ®Google Scholar
• Jiang Z, Chen K, Cheng L, et al. Resveratrol and cancer treatment: updates. Format. 2017;1403:59–69.
   Google Scholar
• Yousef M, Vlachogiannis IA, Tsiani E, et al. Effects of Resveratrol against Lung Cancer: in Vitro and In Vivo Studies. Nutrients. 2017;9:E1231.
   PubMed Web of Science ®Google Scholar
• Kim YN, Choe SR, Cho KH, et al. Resveratrol suppresses breast cancer cell invasion by inactivating a RhoA/YAP signaling axis. Exp Mol Med. 2017;49:e296.
   PubMed Web of Science ®Google Scholar
• D’Asti E, Huang A, Kool M, et al. Tissue factor regulation by miR-520g in primitive neuronal brain tumor cells: a possible link between oncomirs and the vascular tumor microenvironment. Am J Pathol. 2016;186:446–459.
   PubMed Web of Science ®Google Scholar
• Okuno Y, Varela AM, Ding LW, et al. Genomic and molecular characterization of esophageal squamous cell carcinoma. Nat Genet. 2014;46:467–473.
   PubMed Web of Science ®Google Scholar
• Yamazaki M, Maruyama S, Abé T, et al. Rac1-dependent phagocytosis of apoptotic cells by oral squamous cell carcinoma cells: a possible driving force for tumor progression. Exp Cell Res. 2020;392(1):112013.
   PubMed Web of Science ®Google Scholar
• Chen YL, Wu WL, Jang CW, et al. Interferon-stimulated gene 15 modulates cell migration by interacting with Rac1 and contributes to lymph node metastasis of oral squamous cell carcinoma cells. Oncogen. 2019;38(23):4480–4495.
   PubMed Web of Science ®Google Scholar
• Su YF, Liang CY, Huang CY, et al. A putative novel protein, DEPDC1B, is overexpressed in oral cancer patients, and enhanced anchorage-independent growth in oral cancer cells that is mediated b Rac1 and ERK. J Biomed Sci. 2014;21(1):67–72.
   PubMedGoogle Scholar