2,258
Views
26
CrossRef citations to date
0
Altmetric
Research Paper

Rosmarinic acid inhibits proliferation and migration, promotes apoptosis and enhances cisplatin sensitivity of melanoma cells through inhibiting ADAM17/EGFR/AKT/GSK3β axis

, , &
Pages 3065-3076 | Received 02 Apr 2021, Accepted 04 Jun 2021, Published online: 05 Jul 2021

References

  • Kozovska Z, Gabrisova V, Kucerova L. Malignant melanoma: diagnosis, treatment and cancer stem cells. Neoplasma. 2016;63:510–517.
  • Pavri SN, Clune J, Ariyan S, et al. Malignant melanoma: beyond the basics. Plast Reconstr Surg. 2016;138:330e–340e.
  • Huang SK, Hoon DS. Liquid biopsy utility for the surveillance of cutaneous malignant melanoma patients. Mol Oncol. 2016;10:450–463.
  • Ngo YL, Lau CH, Chua LS. Review on rosmarinic acid extraction, fractionation and its anti-diabetic potential. Food Chem Toxicol. 2018;121:687–700.
  • Swamy MK, Sinniah UR, Ghasemzadeh A. Anticancer potential of rosmarinic acid and its improved production through biotechnological interventions and functional genomics. Appl Microbiol Biotechnol. 2018;102:7775–7793.
  • Alagawany M, Abd El-Hack ME, Farag MR, et al. Rosmarinic acid: modes of action, medicinal values and health benefits. Anim Health Res Rev. 2017;18:167–176.
  • Rahbardar MG, Amin B, Mehri S, et al. Rosmarinic acid attenuates development and existing pain in a rat model of neuropathic pain: an evidence of anti-oxidative and anti-inflammatory effects. Phytomedicine. 2018;40:59–67.
  • Lee J, Kim YS, Park D. Rosmarinic acid induces melanogenesis through protein kinase A activation signaling. Biochem Pharmacol. 2007;74(7):960–968.
  • Alcaraz M, Alcaraz-Saura M, Achel DG, Lopez-Morata JA and Castillo J. Radiosensitizing effect of rosmarinic acid in metastatic melanoma B16F10 cells. Anticancer Res. 2014;34:1913–1921.
  • Zunke F, Rose-John S. The shedding protease ADAM17: physiology and pathophysiology. Biochim biophys Acta. Mol Cell Res. 2017;1864: 2059–2070. .
  • Düsterhöft S, Lokau J, Garbers C. The metalloprotease ADAM17 in inflammation and cancer. Pathol Res Pract. 2019;215:152410.
  • Moss ML, Minond D. Recent advances in ADAM17 research: a promising target for cancer and inflammation. Mediators Inflamm. 2017;2017:9673537.
  • Zhang Q, Wang C, Han X, Ge Z and Zhang G. Knockdown of ADAM17 inhibits cell proliferation and increases oxaliplatin sensitivity in HCT-8 colorectal cancer through EGFR-PI3K-AKT activation. Biochem Biophys Res Commun. 2018;503:2333–2339.
  • Waer CN, Kaur P, Tumur Z, et al. Rosmarinic acid/ blue light combination treatment inhibits head and neck squamous cell carcinoma in vitro. Anticancer Res. 2020;40:751–758.
  • Jang Y, Hwang K, Choi K. Rosmarinic acid, a component of rosemary tea, induced the cell cycle arrest and apoptosis through modulation of HDAC2 expression in prostate cancer cell lines. Nutrients. 2018;10.
  • Chen X, Zhang B, Yuan X, et al. Isoliquiritigenin-induced differentiation in mouse melanoma B16F0 cell line. Oxid Med Cell Longev. 2012;2012:534934.
  • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25:402–408.
  • Ko YH, Kim SK, Lee SY, et al. Flavonoids as therapeutic candidates for emotional disorders such as anxiety and depression. Arch Pharm Res. 2020;43:1128–1143.
  • Kong M, Xie K, Lv M, et al. Anti-inflammatory phytochemicals for the treatment of diabetes and its complications: lessons learned and future promise. Biomed Pharmacothe. 2020;133:110975.
  • Kim GD, Park YS. Jin YH and Park CS: production and applications of rosmarinic acid and structurally related compounds. Appl Microbiol Biotechnol. 2015;99:2083–2092.
  • Petersen M, Simmonds MS. Rosmarinic acid. Phytochemistry. 2003;62:121–125.
  • Messeha SS, Zarmouh NO. Asiri A and Soliman KFA: rosmarinic acid-induced apoptosis and cell cycle arrest in triple-negative breast cancer cells. Eur J Pharmacol. 2020;885:173419.
  • Lin M, Zhang BX, Zhang C, et al. Ginsenosides Rb1 and Rg1 stimulate melanogenesis in human epidermal melanocytes via PKA/CREB/MITF signaling. Evid Based Complement Alternat Med. 2014;2014:892073.
  • Xu W, Yang F, Zhang Y, et al. Protective effects of rosmarinic acid against radiation-induced damage to the hematopoietic system in mice. J Radiat Res. 2016;57:356–362.
  • Li F, Fu Y, Jiang D, et al. Reversal effect of rosmarinic acid on multidrug resistance in SGC7901/Adr cell. J Asian Nat Prod Res. 2013;15:276–285.
  • Liao XZ, Gao Y, Sun LL, et al. Rosmarinic acid reverses non-small cell lung cancer cisplatin resistance by activating the MAPK signaling pathway. Phytother Res. 2020;34:1142–1153.
  • Lešnik S, Furlan V, Bren U. Rosemary (Rosmarinus officinalis L.): extraction techniques, analytical methods and health-promoting biological effects. Phytochem Rev. 2021.
  • Afonso AF, Pereira OR, Cardoso SM. Health-promoting effects of thymus phenolic-rich extracts: antioxidant, anti-inflammatory and antitumoral properties. Basel, Switzerland: Antioxidants;2020;9.
  • Gangemi R, Amaro A, Gino A, et al. ADAM10 correlates with uveal melanoma metastasis and promotes in vitro invasion. Pigment Cell Melanoma Res. 2014;27:1138–1148.
  • Cireap N, Narita D. Molecular profiling of ADAM12 and ADAM17 genes in human malignant melanoma. Pathol Oncol Res. 2013;19:755–762.