PTB domain and leucine zipper motif 1 (APPL1) inhibits myocardial ischemia/hypoxia-reperfusion injury via inactivation of apoptotic protease activating factor-1 (APAF-1)/Caspase9 signaling pathway

References

• Hentia C, Rizzato A, Camporesi E, et al. Sﺅ√ndesc D and Bosco G. An overview of protective strategies against ischemia/reperfusion injury: the role of hyperbaric oxygen preconditioning. Brain Behav. 2018;8:e00959.
   PubMed Web of Science ®Google Scholar
• Duan L, Liang C, Li X, et al. Wu N and Jia D. Lycopene restores the effect of ischemic postconditioning on myocardial ischemiaﻗ°∞reperfusion injury in hypercholesterolemic rats. Int J Mol Med. 2019;43:2451–2461.
   PubMed Web of Science ®Google Scholar
• Paradies V, Chan MHH, Hausenloy DJ. Strategies for Reducing Myocardial Infarct Size Following STEMI. In: Watson TJ, Ong PJL, Tcheng JE, editors. Primary Angioplasty: a Practical Guide. Singapore: 2018, The Author(s); 2018. p. 307–322.
   Google Scholar
• Jubair S, Li J, Dehlin HM, et al. Levick SP and Janicki JS. Substance P induces cardioprotection in ischemia-reperfusion via activation of AKT. Am J Physiol Heart Circ Physiol. 2015;309(4):H676–684.
   PubMed Web of Science ®Google Scholar
• Pu Y, Wu D. Lu X and Yang L. Effects of GCN2/eIF2ﺧ١ on myocardial ischemia/hypoxia reperfusion and myocardial cells injury. Am J Transl Res. 2019;11:5586–5598.
   PubMed Web of Science ®Google Scholar
• Thind GS, Agrawal PR, Hirsh B, et al. Mechanisms of myocardial ischemia-reperfusion injury and the cytoprotective role of minocycline: scope and limitations. Future Cardiol. 2015;11(1):61–76.
   PubMed Web of Science ®Google Scholar
• Martin Del Campo SE, Latchana N, Levine KM, et al. 3rd. MiR-21 enhances melanoma invasiveness via inhibition of tissue inhibitor of metalloproteinases 3 expression: in vivo effects of MiR-21 inhibitor. PLoS One. 2015;10(1): e0115919.
   PubMedGoogle Scholar
• Chen L, Zhang D, Yu L, et al. MIAT reduces apoptosis of cardiomyocytes after ischemia/reperfusion injury. Bioengineered. 2019;10(1):121–132.
   PubMed Web of Science ®Google Scholar
• Jiao H, Chen R, Jiang Z, et al. miR-22 protect PC12 from ischemia/reperfusion-induced injury by targeting p53 upregulated modulator of apoptosis (PUMA). Bioengineered. 2020;11(1):209–218.
   PubMed Web of Science ®Google Scholar
• Liu K, Zhao D, Wang D. LINC00528 regulates myocardial infarction by targeting the miR-143-3p/COX-2 axis. Bioengineered. 2020;11(1):11–18.
   PubMed Web of Science ®Google Scholar
• Mao S, Tian S, Luo X, et al. Overexpression of PLK1 relieved the myocardial ischemia-reperfusion injury of rats through inducing the mitophagy and regulating the p-AMPK/FUNDC1 axis. Bioengineered. 2021;12(1):2676–2687.
   PubMed Web of Science ®Google Scholar
• Artimani T, Najafi R. APPL1 as an important regulator of insulin and adiponectin-signaling pathways in the PCOS: a narrative review. Cell Biol Int. 2020;44(8):1577–1587.
   PubMed Web of Science ®Google Scholar
• Fang H, Judd RL. Adiponectin Regulation and Function. Compr Physiol. 2018;8:1031–1063.
   PubMed Web of Science ®Google Scholar
• Hongtao C, Youling F, Fang H, et al. Curcumin alleviates ischemia reperfusion-induced late kidney fibrosis through the APPL1/Akt signaling pathway. J Cell Physiol. 2018;233(11):8588–8596.
   PubMed Web of Science ®Google Scholar
• Xu N, Zhang Y, Doycheva DM, et al. Adiponectin attenuates neuronal apoptosis induced by hypoxia-ischemia via the activation of AdipoR1/APPL1/LKB1/AMPK pathway in neonatal rats. Neuropharmacology. 2018;133:415–428.
   PubMed Web of Science ®Google Scholar
• Park M, Youn B, Zheng X-L, et al. Globular adiponectin, acting via AdipoR1/APPL1, protects H9c2 cells from hypoxia/reoxygenation-induced apoptosis. PLoS One. 2011;6(4):e19143.
   PubMed Web of Science ®Google Scholar
• Shakeri R, Kheirollahi A, Davoodi J. Apaf-1: regulation and function in cell death. Biochimie. 2017;135:111–125.
   PubMed Web of Science ®Google Scholar
• Ferraro E, Pesaresi MG, De Zio D, et al. Apaf1 plays a pro-survival role by regulating centrosome morphology and function. J Cell Sci. 2011;124(20):3450–3463.
   PubMed Web of Science ®Google Scholar
• Li Y, Liang P, Jiang B, et al. Liu Z and Xiao X. CARD9 inhibits mitochondria-dependent apoptosis of cardiomyocytes under oxidative stress via interacting with Apaf-1. Free Radic Biol Med. 2019;141:172–181.
   PubMed Web of Science ®Google Scholar
• Wang Y, Zhang Q, Zhong L, et al. Apoptotic Protease Activating Factor-1 Inhibitor Mitigates Myocardial Ischemia Injury via Disturbing Procaspase-9 Recruitment by Apaf-1. Oxid Med Cell Longev. 2017;2017:9747296.
   PubMed Web of Science ®Google Scholar
• Fang J, Hu F, Ke D, et al. N,N-dimethylsphingosine attenuates myocardial ischemia–reperfusion injury by recruiting regulatory T cells through PI3K/Akt pathway in mice. Basic Res Cardiol. 2016;111(3):32.
   PubMed Web of Science ®Google Scholar
• Li W, Li W, Leng Y, et al. Ferroptosis Is Involved in Diabetes Myocardial Ischemia/Reperfusion Injury Through Endoplasmic Reticulum Stress. DNA Cell Biol. 2020;39(2):210–225.
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25(4):402–408.
   PubMed Web of Science ®Google Scholar
• Li W, Li Y, Chu Y, et al. PLCE1 promotes myocardial ischemia-reperfusion injury in H/R H9c2 cells and I/R rats by promoting inflammation. Biosci Rep. 2019;39(7).
   Web of Science ®Google Scholar
• CaﺅŸlayan F, CaﺅŸlayan O, Gunel E, et al. Intestinal ischemia-reperfusion and plasma enzyme levels. Pediatr Surg Int. 2002;18(4):255–257.
   PubMed Web of Science ®Google Scholar
• Zou Y, Kim D, Yagi M, et al. Application of LDH-release assay to cellular-level evaluation of the toxic potential of harmful algal species. Biosci Biotechnol Biochem. 2013;77(2):345–352.
   PubMed Web of Science ®Google Scholar
• Sue Y-M, Cheng C-F, Chang -C-C, et al. Antioxidation and anti-inflammation by haem oxygenase-1 contribute to protection by tetramethylpyrazine against gentamicin-induced apoptosis in murine renal tubular cells. Nephrol Dial Transplant. 2008;24(3):769–777.
   PubMed Web of Science ®Google Scholar
• Viswanadha VP, Dhivya V, Beeraka NM, et al. The protective effect of piperine against isoproterenol-induced inflammation in experimental models of myocardial toxicity. Eur J Pharmacol. 2020;885:173524.
   PubMed Web of Science ®Google Scholar
• Gan J, Qian W, Lin S. Umbelliferone Alleviates Myocardial Ischemia: the Role of Inflammation and Apoptosis. Inflammation. 2018;41(2):464–473.
   PubMed Web of Science ®Google Scholar
• Wang X, Guo Z, Ding Z, et al. Inflammation, Autophagy, and Apoptosis After Myocardial Infarction. J Am Heart Assoc. 2018;7(9):e008024..
   Google Scholar
• Yao L, Chen H, Wu Q, et al. Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial I/Rﺁ injury via PINK-mediated autophagy. Int J Mol Med. 2019;44:1048–1062.
   PubMed Web of Science ®Google Scholar
• Du Toit EF, Tai WS, Cox A, et al. Synergistic effects of low-level stress and a Western diet on metabolic homeostasis, mood, and myocardial ischemic tolerance. Am J Physiol Regul Integr Comp Physiol. 2020;319(3):R347–r357.
   PubMed Web of Science ®Google Scholar
• Zhang W, Zhang Y, Ding K, et al. Involvement of JNK1/2-NF-κBp65 in the regulation of HMGB2 in myocardial ischemia/reperfusion-induced apoptosis in human AC16 cardiomyocytes. Biomed Pharmacother. 2018;106:1063–1071.
   PubMed Web of Science ®Google Scholar
• Lv S, Ju C, Peng J, et al. 25-Hydroxycholesterol protects against myocardial ischemia-reperfusion injury via inhibiting PARP activity. Int J Biol Sci. 2020;16(2):298–308.
   PubMed Web of Science ®Google Scholar
• Lim B, Jung K, Gwon Y, et al. Cardioprotective role of APIP in myocardial infarction through ADORA2B. Cell Death Dis. 2019;10(7):511.
   PubMedGoogle Scholar